Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils

scientific article published on 22 June 2016

Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP28556
P932PMC publication ID4916511
P698PubMed publication ID27328755

P2093author name stringMarc Lütgehetmann
Till Krech
Joerg Heeren
Antonella Carambia
Johannes Herkel
Christiane Wiegard
Max Preti
Jan-Hendrik Kozik
Tanja Trautmann
P2860cites workCutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytesQ22254042
Immune responses to HCV and other hepatitis virusesQ26866955
Control of adaptive immunity by the innate immune systemQ27026513
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitisQ27349825
A new mathematical model for relative quantification in real-time RT-PCRQ27860781
TREM-1 amplifies inflammation and is a crucial mediator of septic shockQ28185818
EASL clinical practice guidelines: Management of chronic hepatitis B virus infectionQ29615868
Histological grading and staging of chronic hepatitisQ29619625
The burden of liver disease in Europe: a review of available epidemiological dataQ30590517
Soluble form of the triggering receptor expressed on myeloid cells-1 as a marker of microbial infectionQ33723537
Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cellsQ58130729
Susceptibility to murine lymphocytic choriomeningitis maps to class I MHC genes—a model for MHC/disease associationsQ59064490
Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytesQ59324295
Use of Ly6G-specific monoclonal antibody to deplete neutrophils in miceQ81332054
Defective T helper response of hepatocyte-stimulated CD4 T cells impairs antiviral CD8 response and viral clearanceQ81514229
Expression of TREM-1 in hepatic stellate cells and prognostic value in hepatitis B-related hepatocellular carcinomaQ83644015
EASL Clinical Practice Guidelines: management of hepatitis C virus infectionQ86939378
Triggering receptor expressed on myeloid cells-1 (TREM-1): a new player in antiviral immunity?Q34573916
Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by marburg and ebola virusesQ34717923
TREMs in the immune system and beyondQ35140795
CD8 T cell-initiated blood-brain barrier disruption is independent of neutrophil supportQ36139810
The TREM receptor family and signal integrationQ36655903
Neutrophils mediate immunopathology and negatively regulate protective immune responses during fatal bacterial infection-induced toxic shockQ36826912
The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinomaQ36959905
Immunobiology and pathogenesis of viral hepatitisQ37014739
TREM and TREM-like receptors in inflammation and diseaseQ37297533
Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemiaQ37363311
TREM-1 deficiency can attenuate disease severity without affecting pathogen clearanceQ37488144
CD4+ T-cell help is required for effective CD8+ T cell-mediated resolution of acute viral hepatitis in miceQ37500448
Host mechanisms in viral hepatitisQ37749260
TREM-1: intracellular signaling pathways and interaction with pattern recognition receptorsQ38056337
TREM-1 modulation during early stages of dengue virus infectionQ40220598
TREM-1 ligand expression on platelets enhances neutrophil activationQ40220719
Regulation of immunopathology in hepatitis B virus infectionQ41182688
Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well platesQ41681194
Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1.Q41986614
Contributions of the lymphocytic choriomeningitis virus glycoprotein and polymerase to strain-specific differences in murine liver pathogenicityQ45407918
Measurement of polyclonal and antigen-specific cytotoxic T cell functionQ46630058
IL-17 neutralization significantly ameliorates hepatic granulomatous inflammation and liver damage in Schistosoma japonicum infected miceQ47649658
Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumoniaQ48025823
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectviral hepatitisQ1983841
P304page(s)28556
P577publication date2016-06-22
P1433published inScientific ReportsQ2261792
P1476titleAttenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils
P478volume6

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cites work (P2860)
Q90249953Mechanisms of action of ruxolitinib in murine models of hemophagocytic lymphohistiocytosis
Q101410005Neutrophils in liver diseases: pathogenesis and therapeutic targets
Q78177362TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function.
Q40044627The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis.

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