TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function.

scientific article published on 12 November 2019

TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MBIO.02638-19
P932PMC publication ID6851287
P698PubMed publication ID31719184

P50authorGrant R. CampbellQ37372968
P2093author name stringStephen A Spector
Rachel K To
P2860cites workHIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cellsQ91509532
HIV-1 Tat protein enhances microtubule polymerizationQ21093229
Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1Q21133706
Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosisQ21144780
The C Terminus of HIV-1 Tat Modulates the Extent of CD178-mediated Apoptosis of T CellsQ22248066
The Glutamine-rich Region of the HIV-1 Tat Protein Is Involved in T-cell ApoptosisQ22248069
Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytesQ22254042
HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim.Q24543241
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosisQ24554008
Triggering receptor expressed on myeloid cells receptor family modulators: a patent reviewQ26999265
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complexQ28141249
A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune responseQ28185000
TREM-1 amplifies inflammation and is a crucial mediator of septic shockQ28185818
Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: differential regulation of activation and survivalQ28254937
Complete nucleotide sequence of the AIDS virus, HTLV-IIIQ28259080
Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humansQ28345408
Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates.Q28378727
Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoproteinQ28472613
Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagyQ28483647
The role of mononuclear phagocytes in HTLV-III/LAV infectionQ29618676
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.Q29619254
High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.Q30570557
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statisticsQ31016898
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptorsQ31057747
Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by marburg and ebola virusesQ34717923
Differential induction of rat neuronal excitotoxic cell death by human immunodeficiency virus type 1 clade B and C tat proteins.Q35003533
Eradication of HIV-1 from the macrophage reservoir: an uncertain goal?Q35544355
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations.Q35720063
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivationQ36409885
Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.Q36477755
A systems biology approach reveals that tissue tropism to West Nile virus is regulated by antiviral genes and innate immune cellular processesQ36594860
The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral productionQ36685165
Macrophages sustain HIV replication in vivo independently of T cellsQ36737917
Overcoming pharmacologic sanctuariesQ36915933
The Effect of Latency Reversal Agents on Primary CD8+ T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus EradicationQ37034469
Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 regionQ37111282
Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef proteinQ37620634
New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.Q37695001
Plasma membrane signaling in HIV-1 infectionQ38117477
HIV-1 Eradication: Early Trials (and Tribulations).Q38675631
HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1.Q38970292
Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survivalQ39006664
Extracellular regulated kinase phosphorylates mitofusin 1 to control mitochondrial morphology and apoptosis.Q39847516
TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1.Q40106582
Serum sTREM-1 level is quite higher in Crimean Congo Hemorrhagic Fever, a viral infectionQ40118172
Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxinQ40119859
TREM-1 modulation during early stages of dengue virus infectionQ40220598
TREM-1 ligand expression on platelets enhances neutrophil activationQ40220719
HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapyQ40240401
Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteinsQ40641586
Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophilsQ40689296
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signalsQ40770875
HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim.Q41921236
Enzyme-linked immunosorbent assay (ELISA) for the specific detection of apoptotic cells and its application to rapid drug screeningQ43625135
Human immunodeficiency virus 1 favors the persistence of infection by activating macrophages through TNF.Q45556491
Human Primary Macrophages Derived In Vitro from Circulating Monocytes Comprise Adherent and Non-Adherent Subsets with Differential Expression of Siglec-1 and CD4 and Permissiveness to HIV-1 InfectionQ47141069
Resistance of HIV-infected macrophages to CD8+ T lymphocyte-mediated killing drives activation of the immune system.Q53693959
Triggering receptor expressed on myeloid cells (TREM-1) is regulated post-transcriptionally and its ligand is present in the sera of some septic patients.Q54587602
Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epitheliumQ56000938
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptorsQ57184686
SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T CellsQ57814134
Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophagesQ64115299
HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapyQ91341307
P4510describes a project that usesImageJQ1659584
P433issue6
P577publication date2019-11-12
P1433published inmBioQ15817061
P1476titleTREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function.
P478volume10

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cites work (P2860)
Q98197761Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults
Q99550889CD4+ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy
Q106453158SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway
Q97904775SMAC mimetics induce autophagy-dependent apoptosis of HIV-1-infected macrophages
Q89983634TREM-1 activation is a potential key regulator in driving severe pathogenesis of enterovirus A71 infection

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