| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M209155200 |
| P698 | PubMed publication ID | 12370176 |
| P50 | author | Michael Toft Overgaard | Q47805032 |
| Claus Oxvig | Q56430506 | ||
| Kathrin Weyer | Q56950804 | ||
| Lisbeth S Laursen | Q64681314 | ||
| Linda Giudice | Q91869487 | ||
| P2093 | author name string | Henning B Boldt | |
| Lars Sottrup-Jensen | |||
| Peter Ebbesen | |||
| Michael Christiansen | |||
| P2860 | cites work | The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A | Q22009032 |
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| Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase | Q24290962 | ||
| The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases | Q24675153 | ||
| Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans | Q27629908 | ||
| Three-dimensional structure of a complement control protein module in solution | Q27649903 | ||
| Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
| Amino acid sequence of human pregnancy-associated plasma protein-A derived from cloned cDNA | Q28115174 | ||
| Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissues | Q28144716 | ||
| Structure and flexibility of the multiple domain proteins that regulate complement activation | Q28202582 | ||
| Matrix metalloproteinase-19 is expressed in myeloid cells in an adhesion-dependent manner and associates with the cell surface | Q28216019 | ||
| Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins' | Q28264338 | ||
| Complete cDNA sequence of the preproform of human pregnancy-associated plasma protein-A. Evidence for expression in the brain and induction by cAMP | Q28277527 | ||
| Insulin-like growth factors and their binding proteins: biological actions | Q28301853 | ||
| Heparan sulfate proteoglycans as extracellular docking molecules for matrilysin (matrix metalloproteinase 7) | Q28564762 | ||
| Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A | Q28616725 | ||
| Functions of cell surface heparan sulfate proteoglycans | Q29618521 | ||
| Expression of haptoglobin-related protein and its potential role as a tumor antigen | Q33837149 | ||
| Pregnancy-associated plasma protein-E (PAPP-E). | Q33920234 | ||
| Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters | Q33994817 | ||
| Order out of complexity--protein structures that interact with heparin | Q34489551 | ||
| Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. | Q34733220 | ||
| CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling | Q35005223 | ||
| Experimental support for a beta-propeller domain in integrin alpha-subunits and a calcium binding site on its lower surface | Q36058293 | ||
| Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis | Q37306486 | ||
| Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations | Q38667678 | ||
| Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? | Q40922726 | ||
| Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro | Q42514222 | ||
| Pregnancy-associated plasma protein A as a marker of acute coronary syndromes | Q43756514 | ||
| Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane. | Q44204070 | ||
| Involvement of the plasmin system in dissociation of the insulin-like growth factor-binding protein complex | Q44921204 | ||
| Early-pregnancy origins of low birth weight | Q47182924 | ||
| Insulinlike growth factor-binding protein proteolysis an emerging paradigm in insulinlike growth factor physiology. | Q53484761 | ||
| Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ovine, Bovine, Porcine, and Equine Ovarian Follicles: Involvement in IGF Binding Protein-4 Proteolytic Degradation and mRNA Expression During Follicular Development | Q58610879 | ||
| P433 | issue | 49 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | proteolysis | Q33123 |
| P304 | page(s) | 47225-47234 | |
| P577 | publication date | 2002-10-04 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats | |
| P478 | volume | 277 |
| Q59882159 | A characteristic signature of insulin-like growth factor (IGF) axis expression during osteogenic differentiation of human dental pulp cells (hDPCs): Potential co-ordinated regulation of IGF action |
| Q90100849 | A common variant of the pregnancy-associated plasma protein-A (PAPPA) gene encodes a protein with reduced proteolytic activity towards IGF-binding proteins |
| Q30388151 | A genome-wide screen identifies PAPP-AA-mediated IGFR signaling as a novel regulator of habituation learning |
| Q40168513 | A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module |
| Q33304677 | Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP protease. |
| Q42864496 | Analysis of pregnancy-associated plasma protein A production in human adult cardiac progenitor cells |
| Q40569861 | Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module |
| Q90343308 | Characterization of mouse pericardial fat: regulation by PAPP-A |
| Q28214228 | Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment |
| Q42487658 | Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol. |
| Q36486160 | Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice |
| Q47280931 | Formation of high-molecular-weight angiotensinogen during pregnancy is a result of competing redox reactions with the proform of eosinophil major basic protein. |
| Q64120330 | IGF-axis confers transformation and regeneration of fallopian tube fimbria epithelium upon ovulation |
| Q33572235 | Indirect targeting of IGF receptor signaling in vivo by substrate-selective inhibition of PAPP-A proteolytic activity |
| Q33330587 | Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding |
| Q38164837 | Insulin growth factor binding proteins as therapeutic targets in type 2 diabetes |
| Q52728979 | Insulin- like Growth Factor-Binding Protein Action in Bone Tissue: A Key Role for Pregnancy- Associated Plasma Protein-A. |
| Q54960663 | Insulin-Like Growth Factor Binding Proteins and IGFBP Proteases: A Dynamic System Regulating the Ovarian Folliculogenesis. |
| Q36629279 | Insulin-like growth factor (IGF) binding protein-4 is both a positive and negative regulator of IGF activity in vivo |
| Q35947007 | Key questions and answers about pregnancy-associated plasma protein-A. |
| Q53764548 | Myocardial and Peripheral Ischemia Causes an Increase in Circulating Pregnancy-Associated Plasma Protein-A in Non-atherosclerotic, Non-heparinized Pigs. |
| Q42288349 | One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology |
| Q90093908 | PAPP-A and the IGF system in atherosclerosis: what's up, what's down? |
| Q37696962 | PAPP-A as a marker of increased long-term risk in patients with chest pain |
| Q34617964 | PAPP-A: a new anti-aging target? |
| Q42040539 | Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo. |
| Q37832610 | Placental regulation of peptide hormone and growth factor activity by proMBP. |
| Q36742290 | Pregnancy-associated plasma protein A (PAPP-A) modulates the early developmental rate in zebrafish independently of its proteolytic activity |
| Q33989224 | Pregnancy-associated plasma protein-A regulates myoblast proliferation and differentiation through an insulin-like growth factor-dependent mechanism |
| Q41601838 | Role of Insulin-like Growth Factor, Insulin-like Growth Factor Receptors, and Insulin-like Growth Factor-binding Proteins in Ovarian Cancer |
| Q40220343 | Surface association of pregnancy-associated plasma protein-A accounts for its colocalization with activated macrophages |
| Q40533687 | The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity |
| Q39593616 | The activity of pregnancy-associated plasma protein A (PAPP-A) as expressed by immunohistochemistry in atherothrombotic plaques obtained by aspiration thrombectomy in patients presenting with a ST-elevation myocardial infarction: a brief communicati |
| Q35187571 | The insulin-like growth factor system: a key determinant role in the growth and selection of ovarian follicles? a comparative species study |
| Q91951608 | The metalloproteinase Papp-aa controls epithelial cell quiescence-proliferation transition |
| Q38908472 | The proteolytic activity of pregnancy-associated plasma protein-A is potentially regulated by stanniocalcin-1 and -2 during human ovarian follicle development |
| Q35690633 | The role of PAPP-A in the IGF system: location, location, location. |
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