In Vivo and in Vitro Effects of Thymosin and Adenosine Deaminase on Adenosine-Deaminase-Deficient Lymphocytes

scientific article published on February 22, 1979

In Vivo and in Vitro Effects of Thymosin and Adenosine Deaminase on Adenosine-Deaminase-Deficient Lymphocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1056/NEJM197902223000802
P953full work available at URLhttp://www.nejm.org/doi/pdf/10.1056/NEJM197902223000802
P698PubMed publication ID310515

P2093author name stringMurphy RA
Rubinstein A
Hirschhorn R
Sicklick M
P2860cites workProgress in clinical immunologyQ27712795
Adenosine deaminase deficiency: disappearance of adenine deoxynucleotides from a patient's erythrocytes after successful marrow transplantationQ28324717
Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiencyQ33957895
Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiencyQ35200011
Adenosine-deaminase deficiency in a child diagnosed prenatallyQ39313034
Restoration of in-vitro lymphocyte responses with exogenous adenosine deaminase in a patient with severe combined immunodeficiencyQ39351548
Successful fetal liver transplantation in a child with severe combined immunodeficiencyQ39354527
Fractionation of the non-histone proteins of antigen-reactive human lymphocytes: criteria for the specificity of antigen uptakeQ39371504
Circulating thymic-hormone activity in congenital immunodeficiencyQ39450626
Lymphocyte differentiation from precursor cells in vitroQ39931226
Adenosine Inhibition of Lymphocyte-Mediated Cytolysis: Possible Role of Cyclic Adenosine MonophosphateQ39939596
Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic diseaseQ40019292
Analysis of human thymocyte subpopulations using discontinuous gradients of albumin: precursor lymphocytes in human thymusQ40019822
Enhancement of sheep red blood cell human lymphocyte rosette formation by the sulfhydryl compound 2-amino ethylisothiouronium bromideQ40303467
Human lymphocytic metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutininQ40324395
Toxicities of adenosine and 2'-deoxyadrenosine in L cells treated with inhibitors of adenosine deaminaseQ40640534
Limited effect of erythrocyte and plasma infusions in adenosine deaminase deficiencyQ40690916
Toward enzyme therapy for lysosomal storage diseasesQ40727508
Effect of cyclic 3',5'-adenosine monophosphate and theophylline on lymphocyte transformation.Q44048535
Immune cell function and recycling of purinesQ44178033
Enzyme replacement therapy for adenosine deaminase deficiency and severe combined immunodeficiencyQ44190198
Severe Combined Immunodeficiency and Adenosine Deaminase DeficiencyQ44231607
Thymosin: effects on normal human blood T-cellsQ48475128
Morphological and functional maturation of human thymic epithelium in culture.Q53710880
Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase.Q54474324
Demonstration of an Intrathymic Defect in a Case of Severe Combined Immunodeficiency DiseaseQ66898341
Hereditary Severe Combined Immunodeficiency and Adenosine Deaminase DeficiencyQ67433448
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)387-392
P577publication date1979-02-01
1979-02-22
P1433published inThe New England Journal of MedicineQ582728
P1476titleIn Vivo and in Vitro Effects of Thymosin and Adenosine Deaminase on Adenosine-Deaminase-Deficient Lymphocytes
P478volume300

Reverse relations

cites work (P2860)
Q40122869Adenosine Deaminase Deficiency and Severe Combined Immunodeficiency Disease
Q36592027Amplification and molecular cloning of murine adenosine deaminase gene sequences
Q40921784Augmentation of antitumor activity of 5'-deoxy-5-fluorouridine by thymosin fraction 5 in mouse bladder cancer cells in vitro and in vivo
Q42121137Capping and adenosine metabolism. Genetic and pharmacologic studies
Q70146458Circulating thymulin and thymosin-alpha 1 activity in pediatric acquired immune deficiency syndrome: in vivo and in vitro studies
Q39812186Clinical Delineation of Adenosine Deaminase Deficiency
Q39836472Complete and partial adenosine deaminase deficiency. Relationship of immune function to metabolite concentrations, enzyme activity, and effects of therapy
Q35889409Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency.
Q70978754Deoxyadenosine blockade of G0 to G1 transition in lymphocytes: possible involvement of protein kinases
Q28263925Ecto-5-′-nucleotidase deficiency: Association with adenosine deaminase deficiency and nonassociation with deoxyadenosine toxicity
Q72119969Effect of red cell transfusions, thymic hormone and deoxycytidine in severe combined immunodeficiency due to adenosine deaminase deficiency
Q38024130Enzyme Replacement and Other Biochemical Approaches to the Therapy of Adenosine Deaminase Deficiency
Q37042810Erythrocyte adenosine deaminase deficiency without immunodeficiency. Evidence for an unstable mutant enzyme
Q39847433Immunodeficiencies associated with errors in purine metabolism
Q66958073Immunological and biochemical profiles in response to transfusion therapy in an adenosine deaminase-deficient patient with severe combined immunodeficiency disease
Q39908323In vitro and in vivo enhancement of mixed lymphocyte culture reactivity by thymosin in patients with primary immunodeficiency disease
Q40105961Inhibitors of adenosine deaminase
Q72891855Metabolic basis for disorders of purine nucleotide degradation
Q40131415Metabolic defects in immunodeficiency diseases.
Q34257919Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency
Q28367646Plasma deoxyadenosine, adenosine, and erythrocyte deoxyATP are elevated at birth in an adenosine deaminase-deficient child
Q40107870Purine metabolism in relation to leukemia and lymphoid cell differentiation
Q72625834The role of adenosine in the control of immune function
Q40207598Therapy in adenosine deaminase and purine nucleoside phosphorylase deficient patients
Q39831882Thymic peptide hormones: basic properties and clinical applications in cancer
Q41975791Thymosin and the spontaneously diabetic BB rat.

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