Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

scientific article published on July 2002

Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-5793(02)02918-6
P698PubMed publication ID12095637

P2093author name stringShi Yu Yang
Geoffrey Goldspink
P2860cites workSerial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscleQ29615169
Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscleQ31929653
Changes in muscle mass and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overloadQ33674248
Sequence of cDNA encoding human insulin-like growth factor I precursorQ34055481
C2C12 cells: biophysical, biochemical, and immunocytochemical propertiesQ34329764
Prevention of vascular and neural dysfunction in diabetic rats by C-peptide.Q34433058
The potential of muscle stem cellsQ34434476
Exon duplication and divergence in the human preproglucagon geneQ34713786
Two insulin-like growth factor I messenger RNAs are expressed in human liverQ35583911
Identification and analysis of discrete functional domains in the pro region of pre-pro-transforming growth factor beta 1.Q36532809
A mitogenic peptide amide encoded within the E peptide domain of the insulin-like growth factor IB prohormoneQ37178897
Insulin-like growth factor-mediated muscle differentiation: collaboration between phosphatidylinositol 3-kinase-Akt-signaling pathways and myogeninQ40786763
Identification and purification of an intrinsic human muscle myogenic factor that enhances muscle repair and regenerationQ40804383
Insulin and insulin-like growth factor-I responsiveness and signalling mechanisms in C2C12 satellite cells: effect of differentiation and fusionQ41128395
Growth factors in skeletal muscle regenerationQ41276495
Effects of aging on skeletal muscle regenerationQ43490339
Skeletal muscle regeneration in very old ratsQ43586952
Identification of pro-epidermal growth factor and high molecular weight epidermal growth factors in adult mouse urineQ43589833
Insulin-like growth factor I accelerates gastric ulcer healing by stimulating cell proliferation and by inhibiting gastric acid secretionQ43719235
ECM is required for skeletal muscle differentiation independently of muscle regulatory factor expressionQ43852566
Functional inactivation of the IGF-I receptor delays differentiation of skeletal muscle cellsQ46577736
Age-related loss of skeletal muscle function and the inability to express the autocrine form of insulin-like growth factor-1 (MGF) in response to mechanical overload.Q52129352
Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation.Q52178500
Changes in muscle fibre type, muscle mass and IGF-I gene expression in rabbit skeletal muscle subjected to stretch.Q52194733
Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch.Q52200362
IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscleQ73010272
Skeletal muscle satellite cell populations in healthy young and older men and womenQ73179574
P433issue1-3
P407language of work or nameEnglishQ1860
P921main subjectmyoblastQ1956694
P304page(s)156-160
P577publication date2002-07-01
P1433published inFEBS LettersQ1388051
P1476titleDifferent roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation
P478volume522

Reverse relations

cites work (P2860)
Q79420599A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor
Q38253594A review on the mechanisms of blood-flow restriction resistance training-induced muscle hypertrophy
Q40013231A study of the induction of mechano growth factor expression in an in vitro system
Q87113170A synthetic mechano-growth factor E peptide promotes rat tenocyte migration by lessening cell stiffness and increasing F-actin formation via the FAK-ERK1/2 signaling pathway
Q35852683Age-related loss of muscle mass and strength
Q45826802Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle.
Q28575065Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy
Q34234465Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions.
Q45146066Antisense oligonucleotides and short interfering RNAs silencing the cyclin-dependent kinase inhibitor p21 improve proliferation of Duchenne muscular dystrophy patients' primary skeletal myoblasts
Q21143763Association of interleukin-6 signalling with the muscle stem cell response following muscle-lengthening contractions in humans
Q58749611Can Plasma Rich in Growth Factors Be Safe for Parental Use? A Safety Study in the Canine Model
Q37056291Cellular and molecular events controlling skeletal muscle mass in response to altered use.
Q44719055Characterization and identification of a C-terminal amidated mechano growth factor (MGF) analogue in black market products.
Q38110504Characterization and regulation of mechanical loading-induced compensatory muscle hypertrophy
Q59134960Chronic infection stunts macrophage heterogeneity and disrupts immune-mediated myogenesis
Q63805310Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans
Q41891522Design and fabrication of a biodegradable, covalently crosslinked shape-memory alginate scaffold for cell and growth factor delivery
Q48106817Detection and in vitro metabolism of the confiscated peptides BPC 157 and MGF R23H.
Q39664593Differential induction of cellular proliferation, hypertrophy and apoptosis in H9c2 cardiomyocytes by exogenous tissue factor
Q36459287E-peptides control bioavailability of IGF-1.
Q87450734Effect of MGF E-peptide on anabolic and proteolytic signaling pathways in rat m. gastrocnemius medialis
Q31129740Effects of strain on contractile force and number of sarcomeres in series of Xenopus laevis single muscle fibres during long-term culture.
Q28295716Emerging drugs for sarcopenia: age-related muscle wasting
Q63478106Enhanced satellite cell proliferation with resistance training in elderly men and women
Q38945114Examination of alternate codon bias solutions for expression and purification of recombinant mechano-growth factor in Escherichia coli
Q36068056Exercise and circulating insulin-like growth factor I.
Q57476677Exercise and the control of muscle mass in human
Q44401232Expression and Splicing of the Insulin‐Like Growth Factor Gene in Rodent Muscle is Associated with Muscle Satellite (stem) Cell Activation following Local Tissue Damage
Q39463770Expression and purification of two alternative peptides for mechano-growth factor in Escherichia coli
Q42462943Expression and subcellular localization of mechano-growth factor in osteoblasts under mechanical stretch
Q53942483Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise.
Q57024418Expression of insulin-like growth factor I, insulin-like growth factor binding proteins, and collagen mRNA in mechanically loaded plantaris tendon
Q39437832Expression of muscle anabolic and metabolic factors in mechanically loaded MLO-Y4 osteocytes
Q54490830Expression of specific IGFBPs is associated with those of the proliferating and differentiating markers in regenerating rat plantaris muscle.
Q34135241Extrinsic regulation of satellite cell specification
Q36234586Fiber-type composition of the human jaw muscles--(part 1) origin and functional significance of fiber-type diversity
Q36956383Functional deficits and insulin-like growth factor-I gene expression following tourniquet-induced injury of skeletal muscle in young and old rats
Q34275723Gene expression in muscle in response to exercise
Q34576814Gene therapy progress and prospects: Duchenne muscular dystrophy
Q44048126Generation and evaluation of antibodies against human MGF E-peptide by reverse phase protein microarray and reverse competitive ELISA.
Q26746405Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing
Q33569163Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?
Q36333933Human Eb peptide: not just a by-product of pre-pro-IGF1b processing?
Q47366049Human IGF-I propeptide A promotes articular chondrocyte biosynthesis and employs glycosylation-dependent heparin binding
Q38554891Human sports drug testing by mass spectrometry
Q54282437IGF-1 colocalizes with muscle satellite cells following acute exercise in humans.
Q36320501IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors.
Q27024703IL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism?
Q51779098Impact of treadmill locomotor training on skeletal muscle IGF1 and myogenic regulatory factors in spinal cord injured rats.
Q42701900Impairment of IGF-I expression and anabolic signaling following ischemia/reperfusion in skeletal muscle of old mice
Q90482471Insulin-Like Growth Factor I Regulation and Its Actions in Skeletal Muscle
Q35022643Insulin-like growth factor I (IGF-1) Ec/Mechano Growth factor--a splice variant of IGF-1 within the growth plate.
Q35587426Insulin-like growth factor action and skeletal muscle growth, an in vivo perspective
Q34429527Insulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptor
Q63342601Insulin-like growth factors effects on the expression of myogenic regulatory factors in gilthead sea bream muscle cells
Q40335819Intranasal, siRNA Delivery to the Brain by TAT/MGF Tagged PEGylated Chitosan Nanoparticles.
Q53165439Is the -174 C/G polymorphism of the IL6 gene associated with elite power performance? A replication study with two different Caucasian cohorts.
Q91687596Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats
Q43568840Mechano growth factor (MGF) promotes proliferation and inhibits differentiation of porcine satellite cells (PSCs) by down-regulation of key myogenic transcriptional factors
Q33883445Mechano growth factor, a splice variant of IGF-1, promotes neurogenesis in the aging mouse brain
Q50210424Mechano-growth factor enhances differentiation of bone marrow-derived mesenchymal stem cells.
Q46007172Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.
Q38133542Mechano-regulation of alternative splicing
Q47701394Mechanobiology of young and aging tendons: In vivo studies with treadmill running
Q41683501Migration and proliferation of human mesenchymal stem cells is stimulated by different regions of the mechano-growth factor prohormone
Q38761926Mimicking exercise in three-dimensional bioengineered skeletal muscle to investigate cellular and molecular mechanisms of physiological adaptation
Q33735493Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration
Q39571282Modelling in vivo skeletal muscle ageing in vitro using three-dimensional bioengineered constructs.
Q37257924Modulation of GH/IGF-1 axis: potential strategies to counteract sarcopenia in older adults
Q36756794Monocyte/Macrophage-derived IGF-1 Orchestrates Murine Skeletal Muscle Regeneration and Modulates Autocrine Polarization
Q80186853Muscle IGF-I Ea, MGF, and myostatin mRNA expressions after compensatory overload in hypophysectomized rats
Q30434197Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice
Q44533330Muscle satellite (stem) cell activation during local tissue injury and repair
Q33752882Myoferlin is required for insulin-like growth factor response and muscle growth
Q93050407Myoferlin, a multifunctional protein in normal cells, has novel and key roles in various cancers
Q38094701New Modulators for IGF-I Activity within IGF-I Processing Products
Q36538153New fundamental resistance exercise determinants of molecular and cellular muscle adaptations
Q47754257Overload training inhibits phagocytosis and ROS generation of peritoneal macrophages: role of IGF-1 and MGF.
Q34047251PDGF-BB does not accelerate healing in diabetic mice with splinted skin wounds.
Q43195170Passive mechanical forces upregulate the fast myosin heavy chain IId/x via integrin and p38 MAP kinase activation in a primary muscle cell culture
Q83150778Peripheral venous occlusion causing cardiac hypertrophy and changes in biological parameters in rats
Q26778654Physiological and Neural Adaptations to Eccentric Exercise: Mechanisms and Considerations for Training
Q36881964Plasticity of human skeletal muscle: gene expression to in vivo function.
Q35962591Potency of Full-Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Equimolar Concentrations
Q38075849Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training
Q58615342Regulation of Muscle Growth in Early Postnatal Life in a Swine Model
Q42102725Research on mechano growth factor: its potential for optimising physical training as well as misuse in doping
Q36066585Role of IGF-I in follistatin-induced skeletal muscle hypertrophy
Q30446473Running on empty: how p53 controls INS/IGF signaling and affects life span
Q90325612Satellite cell function, intramuscular inflammation and exercise in chronic kidney disease
Q33816665Satellite cells and the muscle stem cell niche
Q26777962Satellite cells in human skeletal muscle plasticity
Q35003261Sequenced response of extracellular matrix deadhesion and fibrotic regulators after muscle damage is involved in protection against future injury in human skeletal muscle
Q35145583Skeletal muscle as an artificial endocrine tissue
Q38095767Skeletal muscle hypertrophy and regeneration: interplay between the myogenic regulatory factors (MRFs) and insulin-like growth factors (IGFs) pathways
Q36325014Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.
Q34322871Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications
Q41682420Specific titin and myomesin domains stimulate myoblast proliferation.
Q35547307Stem cell activation in skeletal muscle regeneration.
Q34097153Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes.
Q54572065Suppression of testosterone does not blunt mRNA expression of myoD, myogenin, IGF, myostatin or androgen receptor post strength training in humans.
Q35567203Sustained delivery of MGF peptide from microrods attracts stem cells and reduces apoptosis of myocytes
Q45732506Synthesis, characterization, and biocompatibility of a novel biomimetic material based on MGF-Ct24E modified poly(D, L-lactic acid).
Q37039373The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction
Q24307354The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle
Q37789610The Mechanisms of Muscle Hypertrophy and Their Application to Resistance Training
Q34548920The Role of GH and IGF-I in Mediating Anabolic Effects of Testosterone on Androgen-Responsive Muscle
Q36224171The behaviour of satellite cells in response to exercise: what have we learned from human studies?
Q33619027The complexity of the IGF1 gene splicing, posttranslational modification and bioactivity
Q36915911The effect of muscle loading on skeletal muscle regenerative potential: an update of current research findings relating to aging and neuromuscular pathology
Q44622913The effect of recombinant human growth hormone and resistance training on IGF-I mRNA expression in the muscles of elderly men.
Q39432413The emerging role of alternative splicing in senescence and aging.
Q33841223The insulin-like growth factor (IGF)-I E-peptides are required for isoform-specific gene expression and muscle hypertrophy after local IGF-I production
Q37327278The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I protein
Q34213640The muscle fiber type-fiber size paradox: hypertrophy or oxidative metabolism?
Q48104841The novel finding of four distinct prepro-IGF-I E domains in a perciform fish, Sciaenops ocellatus, during ontogeny
Q34323600The nuclear localization of MGF receptor in osteoblasts under mechanical stimulation
Q35937545The splicing of the IGF-I gene to yield different muscle growth factors
Q38805077The structure-function relationships of insulin-like growth factor 1 Ec in C2C12 cells
Q38046671The use of nonsteroidal anti-inflammatory drugs for exercise-induced muscle damage: implications for skeletal muscle development
Q53230711Therapeutic ultrasound affects IGF-1 splice variant expression in human skeletal muscle.
Q44963948Transcriptional regulation of IGF-I expression in skeletal muscle
Q37573464Validated treatments and therapeutics prospectives regarding pharmacological products for sarcopenia
Q37707643Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength
Q62655508Zelluläre Regulation des Anabolismus und Katabolismus der Skelettmuskulatur bei Immobilität, im Alter und bei kritisch Kranken

Search more.