Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength

scientific article published on 25 February 2014

Viral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00008.2014
P932PMC publication ID3989742
P698PubMed publication ID24569593
P5875ResearchGate publication ID260381264

P2093author name stringElisabeth R Barton
Becky K Brisson
SooHyun Park
Janelle Spinazzola
P2860cites workMyogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic miceQ72223472
IGF-I treatment improves the functional properties of fast- and slow-twitch skeletal muscles from dystrophic miceQ73739705
Localized infusion of IGF-I results in skeletal muscle hypertrophy in ratsQ74510959
Characterization of a rabbit antihuman mechano growth factor (MGF) polyclonal antibody against the last 24 amino acids of the E domainQ81039886
A synthetic mechano growth factor E Peptide enhances myogenic precursor cell transplantation successQ81227019
The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscleQ24307354
Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle functionQ24642759
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetesQ28345343
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)Q29619910
New insulin-like growth factor (IGF)-precursor sequences from mammalian genomes: the molecular evolution of IGFs and associated peptides in primatesQ31160029
Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscleQ31929653
Post-translational processing of insulin-like growth factorsQ33607311
Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regenerationQ33735493
The insulin-like growth factor (IGF)-I E-peptides are required for isoform-specific gene expression and muscle hypertrophy after local IGF-I productionQ33841223
Sequence of cDNA encoding human insulin-like growth factor I precursorQ34055481
Insulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptorQ34429527
Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscleQ34787562
Self-complementary AAV vectors; advances and applicationsQ34804660
Lack of myostatin results in excessive muscle growth but impaired force generationQ35629418
Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF productionQ36183694
Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissuesQ36457963
E-peptides control bioavailability of IGF-1.Q36459287
The pro-forms of insulin-like growth factor I (IGF-I) are predominant in skeletal muscle and alter IGF-I receptor activationQ36628478
Loss of muscle strength during aging studied at the gene levelQ36932676
The insulin-like growth factor (IGF)-I E-peptides modulate cell entry of the mature IGF-I proteinQ37327278
Mature IGF-I excels in promoting functional muscle recovery from disuse atrophy compared with pro-IGF-IA.Q37679375
Fiber-type discrimination in disuse and glucocorticoid-induced atrophyQ37945510
Sequences of liver cDNAs encoding two different mouse insulin-like growth factor I precursorsQ40419087
Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?Q40472290
Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiationQ40721113
Monoclonal antibodies to the carboxy-terminal Ea sequence of pro-insulin-like growth factor-IA (proIGF-IA) recognize proIGF-IA secreted by IM9 B-lymphocytesQ40794909
Isometric and eccentric force generation assessment of skeletal muscles isolated from murine models of muscular dystrophiesQ41152126
Growth hormone and the insulin-like growth factor system in myogenesisQ41192757
Contractile properties of skeletal muscles from young, adult and aged miceQ41421042
Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activationQ43297220
Expression and Splicing of the Insulin‐Like Growth Factor Gene in Rodent Muscle is Associated with Muscle Satellite (stem) Cell Activation following Local Tissue DamageQ44401232
Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids.Q44904396
Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and developmentQ45171483
Expression of IGF-1 isoforms after exercise-induced muscle damage in humans: characterization of the MGF E peptide actions in vitro.Q45945739
Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.Q46007172
Antiserum developed for the E peptide region of insulin-like growth factor IA prohormone recognizes a serum protein by both immunoblot and radioimmunoassay.Q46031705
Viral expression of insulin-like growth factor-I isoforms promotes different responses in skeletal muscleQ46913649
Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides: evidence for differential processing and regulation in liverQ68511364
Alternative splicing produces messenger RNAs encoding insulin-like growth factor-I prohormones that are differentially glycosylated in vitroQ68592945
P433issue8
P921main subjectpreproinsulinQ7240673
P304page(s)E965-74
P577publication date2014-02-25
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleViral expression of insulin-like growth factor I E-peptides increases skeletal muscle mass but at the expense of strength
P478volume306

Reverse relations

cites work (P2860)
Q92889289Effects of IGF-1 isoforms on muscle growth and sarcopenia
Q40218139Effects of sustained exercise on GH-IGFs axis in gilthead sea bream (Sparus aurata).
Q92022211Functional muscle hypertrophy by increased insulin-like growth factor 1 does not require dysferlin
Q50916181Human IGF-I Eb-peptide induces cell attachment and lamellipodia outspread of metastatic breast carcinoma cells (MDA-MB-231).
Q90482471Insulin-Like Growth Factor I Regulation and Its Actions in Skeletal Muscle
Q54309806Lack of the serum- and glucocorticoid-inducible kinase SGK1 improves muscle force characteristics and attenuates fibrosis in dystrophic mdx mouse muscle.
Q35083679Localized delivery of mechano-growth factor E-domain peptide via polymeric microstructures improves cardiac function following myocardial infarction
Q26825444Optimizing IGF-I for skeletal muscle therapeutics
Q28082188Role of IGF-I signaling in muscle bone interactions

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