A grand challenge for genetics of aging: adding healthy years to our lives.

scientific article published on 7 November 2011

A grand challenge for genetics of aging: adding healthy years to our lives. is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

External links are
P356DOI10.3389/FGENE.2011.00079
P932PMC publication ID3268632
P698PubMed publication ID22303373
P5875ResearchGate publication ID221804069

P50authorBlanka RoginaQ52687930
P2093author name stringBlanka Rogina
P2860cites workA method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial resultsQ28271230
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegansQ28611331
The genetics of ageingQ29547430
Sirtuin activators mimic caloric restriction and delay ageing in metazoansQ29547766
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegansQ29617059
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine functionQ29618026
The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935Q29620325
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogasterQ33665807
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MicroRNAs both promote and antagonize longevity in C. elegans.Q34502279
Genetic studies reveal the role of the endocrine and metabolic systems in agingQ34630640
Brain IRS2 signaling coordinates life span and nutrient homeostasisQ34653913
Gain of survival signaling by down-regulation of three key miRNAs in brain of calorie-restricted miceQ34966622
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old ageQ57268199
A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertilityQ24532227
The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanismsQ24597989
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathwayQ24643816
Association of FOXO3A variation with human longevity confirmed in German centenariansQ24646035
FOXO3A genotype is strongly associated with human longevityQ24647408
Rapamycin fed late in life extends lifespan in genetically heterogeneous miceQ24647805
A C. elegans mutant that lives twice as long as wild typeQ27861054
Regulation of longevity and stress resistance by Sch9 in yeastQ27929987
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanQ28203572
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate proteinQ28211215
P304page(s)79
P577publication date2011-11-07
P1433published inFrontiers in GeneticsQ2499875
P1476titleA grand challenge for genetics of aging: adding healthy years to our lives
P478volume2

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