Deletion of fabN in Enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines

scientific article published on 22 March 2016

Deletion of fabN in Enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/1753425916639669
P698PubMed publication ID27009913

P2093author name stringOtto Holst
Johannes Huebner
Ann-Kristin Diederich
Katarzyna A Duda
Regina Engel
Felipe Romero-Saavedra
P2860cites workDomain swapping between Enterococcus faecalis FabN and FabZ proteins localizes the structural determinants for isomerase activityQ38324444
Skin-Specific Unsaturated Fatty Acids Boost the Staphylococcus aureus Innate Immune Response.Q38824843
Alanine esters of enterococcal lipoteichoic acid play a role in biofilm formation and resistance to antimicrobial peptidesQ41476984
Enterococcus faecalis constitutes an unusual bacterial model in lysozyme resistanceQ41904091
Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutansQ42066522
Incorporation of exogenous fatty acids protects Enterococcus faecalis from membrane-damaging agentsQ42920252
Serum fatty acid levels, dietary style and coronary heart disease in three neighbouring areas in Japan: the Kumihama studyQ44307887
A comparison of pyrrolidide and picolinyl ester derivatives for the identification of fatty acids in natural samples by gas chromatography-mass spectrometryQ45152832
High efficiency introduction of plasmid DNA into glycine treated Enterococcus faecalis by electroporationQ45858708
Identification, characterization, and inhibition of Plasmodium falciparum beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ).Q47934927
Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogensQ57244151
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Bacterial lipids: metabolism and membrane homeostasisQ26829512
Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteriaQ27673052
Antibacterial targets in fatty acid biosynthesisQ28241394
Enterococcus faecalis Glycolipids Modulate Lipoprotein-Content of the Bacterial Cell Membrane and Host Immune ResponseQ28546519
Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesisQ33459561
Role of glycolipids in the pathogenesis of Enterococcus faecalis urinary tract infectionQ33577912
Deletion of the glycosyltransferase bgsB of Enterococcus faecalis leads to a complete loss of glycolipids from the cell membrane and to impaired biofilm formationQ33864218
Functional replacement of the FabA and FabB proteins of Escherichia coli fatty acid synthesis by Enterococcus faecalis FabZ and FabF homologuesQ33979089
Role of mprF1 and mprF2 in the pathogenicity of Enterococcus faecalis.Q34313862
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functionsQ34323476
FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureusQ35105888
Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.Q35216999
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptidesQ36099284
Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysineQ36369306
The biology and future prospects of antivirulence therapiesQ36397902
Inhibiting bacterial fatty acid synthesisQ36464020
Antimycobacterial Activity and Mechanism of Action of NAS-91Q36482806
TLR2 - promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificityQ37136130
The use of platensimycin and platencin to fight antibiotic resistanceQ37203095
The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistanceQ37218845
New vector for efficient allelic replacement in naturally nontransformable, low-GC-content, gram-positive bacteria.Q37597487
P433issue4
P921main subjectfatty acidQ61476
Enterococcus faecalisQ140014
P304page(s)284-293
P577publication date2016-03-22
P1433published inInnate ImmunityQ6035271
P1476titleDeletion of fabN in Enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines
P478volume22

Search more.