scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0896-6273(01)00487-1 |
P698 | PubMed publication ID | 11719205 |
P2093 | author name string | G Yellen | |
D del Camino | |||
P2860 | cites work | The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity | Q22337058 |
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches | Q22337395 | ||
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors | Q27632398 | ||
Biophysical and molecular mechanisms of Shaker potassium channel inactivation | Q29617879 | ||
Silver as a probe of pore-forming residues in a potassium channel | Q30193514 | ||
Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy | Q30472195 | ||
The moving parts of voltage-gated ion channels | Q33671684 | ||
The barium site in a potassium channel by x-ray crystallography | Q33891602 | ||
Activation-dependent subconductance levels in the drk1 K channel suggest a subunit basis for ion permeation and gating | Q33916837 | ||
Potassium blocks barium permeation through a calcium-activated potassium channel | Q34170721 | ||
The internal quaternary ammonium receptor site of Shaker potassium channels | Q34362419 | ||
Multi-ion occupancy alters gating in high-conductance, Ca(2+)-activated K+ channels | Q36410821 | ||
Trapping of organic blockers by closing of voltage-dependent K+ channels: evidence for a trap door mechanism of activation gating. | Q36411850 | ||
Time course of TEA(+)-induced anomalous rectification in squid giant axons | Q36427295 | ||
N-type inactivation and the S4-S5 region of the Shaker K+ channel | Q36435725 | ||
Anomalous effect of permeant ion concentration on peak open probability of cardiac Na+ channels | Q36435845 | ||
Intermediate conductances during deactivation of heteromultimeric Shaker potassium channels | Q36436105 | ||
Selectivity changes during activation of mutant Shaker potassium channels | Q36445050 | ||
Voltage gating of ion channels | Q40391780 | ||
The activation gate of a voltage-gated K+ channel can be trapped in the open state by an intersubunit metal bridge | Q41003350 | ||
Ion effects on gating of the Ca(2+)-activated K+ channel correlate with occupancy of the pore | Q41108691 | ||
Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons | Q41761074 | ||
Conformational changes in S6 coupled to the opening of cyclic nucleotide-gated channels | Q42653386 | ||
The inner quaternary ammonium ion receptor in potassium channels of the node of Ranvier | Q42958073 | ||
Multiple products of the Drosophila Shaker gene may contribute to potassium channel diversity | Q46403606 | ||
Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel. | Q52448076 | ||
Immobilisation of gating charge by a substance that simulates inactivation. | Q52705734 | ||
Ionic pores, gates, and gating currents. | Q52724151 | ||
K+ channels close more slowly in the presence of external K+ and Rb+ | Q59079933 | ||
Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates | Q72520684 | ||
Voltage clamp experiments on internally perfused giant axons | Q72695318 | ||
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications | Q73412357 | ||
Gated access to the pore of a voltage-dependent K+ channel | Q73564876 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | voltage | Q25428 |
P304 | page(s) | 649-656 | |
P577 | publication date | 2001-11-01 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | Tight steric closure at the intracellular activation gate of a voltage-gated K(+) channel | |
P478 | volume | 32 |
Q39995529 | A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. |
Q34188472 | A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation |
Q37730860 | A slick, slack pathway through the pore |
Q36295688 | Access of quaternary ammonium blockers to the internal pore of cyclic nucleotide-gated channels: implications for the location of the gate |
Q42621571 | Activation properties of Kv4.3 channels: time, voltage and [K+]o dependence |
Q42035760 | Allosteric coupling of the inner activation gate to the outer pore of a potassium channel |
Q44575118 | Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate |
Q40086058 | An activation gating switch in Kv1.2 is localized to a threonine residue in the S2-S3 linker. |
Q36610027 | An external sodium ion binding site controls allosteric gating in TRPV1 channels |
Q44243367 | Aqueous access channels in subunit a of rotary ATP synthase |
Q37474795 | BK channel opening involves side-chain reorientation of multiple deep-pore residues |
Q42192885 | Base of pore loop is important for rectification, activation, permeation, and block of Kir3.1/Kir3.4. |
Q38044898 | Being flexible: the voltage-controllable activation gate of kv channels. |
Q35549225 | Cadmium-cysteine coordination in the BK inner pore region and its structural and functional implications |
Q35044650 | Channel gating of NMDA receptors |
Q42009472 | Characterization of five RNA editing sites in Shab potassium channels |
Q35145307 | Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating |
Q37040647 | Closed state-coupled C-type inactivation in BK channels |
Q42047997 | Closed-channel block of BK potassium channels by bbTBA requires partial activation. |
Q34185246 | Concerted gating mechanism underlying KATP channel inhibition by ATP. |
Q42078363 | Conformational changes of pore helix coupled to gating of TRPV5 by protons |
Q42775177 | Congruent pattern of accessibility identifies minimal pore gate in a non-symmetric voltage-gated sodium channel |
Q36436648 | Constitutive activation of the Shaker Kv channel |
Q34925195 | Coupled movements in voltage-gated ion channels |
Q36070158 | Coupling between the voltage-sensing and pore domains in a voltage-gated potassium channel. |
Q36436552 | Coupling between voltage sensors and activation gate in voltage-gated K+ channels |
Q42183400 | Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations of mutated Kv channels |
Q36412572 | Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels |
Q36121859 | Coupling of voltage-sensors to the channel pore: a comparative view |
Q36295859 | Cross talk between activation and slow inactivation gates of Shaker potassium channels |
Q36558180 | Cysteine mutagenesis and computer modeling of the S6 region of an intermediate conductance IKCa channel |
Q35123192 | Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region. |
Q37999317 | Cytoplasmic domains and voltage-dependent potassium channel gating. |
Q48830418 | Defining the Conductance of the Closed State in a Voltage-Gated K+ Channel |
Q36295873 | Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction |
Q30484864 | Determinants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity. |
Q44557623 | Different gating mechanisms in glutamate receptor and K+ channels. |
Q33755245 | Differential effect of L-cysteine in isolated whole-bladder preparations from neonatal and adult rats |
Q35240329 | Domain-domain interactions determine the gating, permeation, pharmacology, and subunit modulation of the IKs ion channel |
Q27675968 | Domain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel |
Q34180133 | Effect of S6 tail mutations on charge movement in Shaker potassium channels |
Q40293341 | Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels. |
Q34632406 | Elucidating the molecular basis of action of a classic drug: guanidine compounds as inhibitors of voltage-gated potassium channels |
Q90711493 | Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening |
Q36296111 | Evidence for a deep pore activation gate in small conductance Ca2+-activated K+ channels |
Q44527174 | Evidence for intersubunit interactions between S4 and S5 transmembrane segments of the Shaker potassium channel |
Q37646643 | Evolutionarily conserved intracellular gate of voltage-dependent sodium channels. |
Q36436477 | Extracellular sodium interacts with the HERG channel at an outer pore site |
Q36493546 | Functional architecture of the inner pore of a voltage-gated Ca2+ channel |
Q36299689 | Gating and inward rectifying properties of the MthK K+ channel with and without the gating ring |
Q36491086 | Gating at the selectivity filter in cyclic nucleotide-gated channels |
Q40659405 | Gating dependence of inner pore access in inward rectifier K(+) channels |
Q35569293 | Gating mechanism of KATP channels: function fits form |
Q92859901 | Gating modules of the AMPA receptor pore domain revealed by unnatural amino acid mutagenesis |
Q44588580 | Gating of shaker-type channels requires the flexibility of S6 caused by prolines |
Q37069023 | Gating the pore of P2X receptor channels |
Q28290774 | Glutamate receptor ion channels: structure, regulation, and function |
Q42961365 | How S4 segments move charge. Let me count the ways |
Q24644565 | Inactivation of BK channels by the NH2 terminus of the beta2 auxiliary subunit: an essential role of a terminal peptide segment of three hydrophobic residues |
Q28817852 | Independent movement of the voltage sensors in KV2.1/KV6.4 heterotetramers |
Q24644498 | Influence of permeant ions on voltage sensor function in the Kv2.1 potassium channel |
Q34309921 | Inhibition of large-conductance Ca2+-activated K+ channels by nanomolar concentrations of Ag+. |
Q36140665 | Initial steps in the opening of a Shaker potassium channel |
Q33983069 | Inositol trisphosphate receptor Ca2+ release channels. |
Q90746743 | Insights into the molecular mechanism for hyperpolarization-dependent activation of HCN channels |
Q44671454 | Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels |
Q27674791 | Interactions of Cations with the Cytoplasmic Pores of Inward Rectifier K+ Channels in the Closed State |
Q34315701 | Intracellular gate opening in Shaker K+ channels defined by high-affinity metal bridges. |
Q36493535 | Investigating the putative glycine hinge in Shaker potassium channel. |
Q34311621 | Ion channel associated diseases: overview of molecular mechanisms |
Q38247898 | Ion channel engineering: perspectives and strategies |
Q30539929 | K channel gating by an affinity-switching selectivity filter |
Q36493498 | K channel subconductance levels result from heteromeric pore conformations |
Q43240829 | Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues |
Q36438058 | Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization |
Q28654247 | K⁺ channel gating: C-type inactivation is enhanced by calcium or lanthanum outside |
Q59084719 | Life's transistors |
Q36436660 | Ligand-induced closure of inward rectifier Kir6.2 channels traps spermine in the pore |
Q27681473 | Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1. |
Q37023303 | Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel. |
Q42603548 | Localization of PIP2 activation gate in inward rectifier K+ channels |
Q40713986 | Localization of the activation gate for small conductance Ca2+-activated K+ channels. |
Q36493538 | Localization of the activation gate of a voltage-gated Ca2+ channel |
Q48823550 | Mechanisms of the inhibition of Shaker potassium channels by protons |
Q35584086 | Merging functional studies with structures of inward-rectifier K+ channels |
Q37039299 | Modification of K+ channel-drug interactions by ancillary subunits. |
Q42686706 | Modulation of MthK potassium channel activity at the intracellular entrance to the pore. |
Q36445000 | Molecular Coupling between Voltage Sensor and Pore Opening in the Arabidopsis Inward Rectifier K+ Channel KAT1 |
Q34800154 | Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels |
Q30482832 | Molecular dynamics simulation of Kv channel voltage sensor helix in a lipid membrane with applied electric field |
Q36353448 | Molecular mechanism for depolarization-induced modulation of Kv channel closure |
Q36436615 | Movements near the gate of a hyperpolarization-activated cation channel |
Q33922826 | Multi-scale electrophysiology modeling: from atom to organ |
Q61797851 | New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question |
Q51129304 | Nitric oxide activates TRP channels by cysteine S-nitrosylation. |
Q40157311 | On the mechanism of TBA block of the TRPV1 channel. |
Q47427190 | Opening the gate in potassium channels |
Q36568507 | Opening the shaker K+ channel with hanatoxin |
Q36380573 | Patch fluorometry: shedding new light on ion channels |
Q36446389 | Perspectives on: conformational coupling in ion channels: conformational coupling in BK potassium channels |
Q36539721 | Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel |
Q42152315 | Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel |
Q37385262 | Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome |
Q34313783 | Pore-opening mechanism in trimeric P2X receptor channels |
Q34368444 | Position and motions of the S4 helix during opening of the Shaker potassium channel |
Q34446397 | Potassium channel mechanics |
Q35589981 | Potassium channels |
Q38151974 | Potassium channels: structures, diseases, and modulators |
Q34985100 | Potassium channels: structures, models, simulations. |
Q24600608 | Principles of conduction and hydrophobic gating in K+ channels |
Q39704220 | Probing pore constriction in a ligand-gated ion channel by trapping a metal ion in the pore upon agonist dissociation |
Q36299751 | Probing the cavity of the slow inactivated conformation of shaker potassium channels |
Q33634079 | Proline scan of the HERG channel S6 helix reveals the location of the intracellular pore gate. |
Q34196066 | Redox-sensitive extracellular gates formed by auxiliary β subunits of calcium-activated potassium channels |
Q43233633 | Regulatory role of the extreme C-terminal end of the S6 inner helix in C-terminal-truncated Kv1.2 channel activation |
Q36295815 | Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6. |
Q34546935 | Role of conserved glycines in pH gating of Kir1.1 (ROMK) |
Q42634179 | Role of the S6 C-terminus in KCNQ1 channel gating |
Q42152089 | STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate |
Q40115311 | Saturation and microsecond gating of current indicate depletion-induced instability of the MaxiK selectivity filter |
Q36445276 | Scanning the intracellular S6 activation gate in the shaker K+ channel |
Q36412653 | Secondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels |
Q35789217 | Selectivity filter gating in large-conductance Ca(2+)-activated K+ channels |
Q56529660 | Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs |
Q36837526 | Spatial positioning of CFTR's pore-lining residues affirms an asymmetrical contribution of transmembrane segments to the anion permeation pathway |
Q40092801 | Stability of the Shab K+ channel conductance in 0 K+ solutions: the role of the membrane potential |
Q36445416 | Stabilizing the closed S6 gate in the Shaker Kv channel through modification of a hydrophobic seal. |
Q36295841 | State-dependent block of BK channels by synthesized shaker ball peptides |
Q35629078 | Status of the intracellular gate in the activated-not-open state of shaker K+ channels |
Q27318375 | Structural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments |
Q100395410 | Structural basis for pH gating of the two-pore domain K+ channel TASK2 |
Q35503245 | Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7). |
Q45949168 | Structural determinants of gating in the TRPV1 channel. |
Q42861247 | Structural determinants of the closed KCa3.1 channel pore in relation to channel gating: results from a substituted cysteine accessibility analysis |
Q42595144 | Structural determinants of the regulation of the voltage-gated potassium channel Kv2.1 by the modulatory α-subunit Kv9.3. |
Q36493622 | Structure and anticipatory movements of the S6 gate in Kv channels |
Q38039087 | TRP channels: sensors and transducers of gasotransmitter signals. |
Q38222944 | TRPs as chemosensors (ROS, RNS, RCS, gasotransmitters). |
Q36558208 | Tail end of the s6 segment: role in permeation in shaker potassium channels |
Q42686974 | The (beta)gamma subunits of G proteins gate a K(+) channel by pivoted bending of a transmembrane segment |
Q94464114 | The EAG Voltage-Dependent K+ Channel Subfamily: Similarities and Differences in Structural Organization and Gating |
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Q41558471 | The S4-S5 linker of KCNQ1 channels forms a structural scaffold with the S6 segment controlling gate closure |
Q57463886 | The S6 gate in regulatory Kv6 subunits restricts heteromeric K channel stoichiometry |
Q44606572 | The Selectivity Filter May Act as the Agonist-activated Gate in the G Protein-activated Kir3.1/Kir3.4 K+ Channel |
Q61135723 | The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel |
Q34277792 | The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels. |
Q26771787 | The hitchhiker's guide to the voltage-gated sodium channel galaxy |
Q83226302 | The ion selectivity filter is not an activation gate in TRPV1-3 channels |
Q34227906 | The ligand-sensitive gate of a potassium channel lies close to the selectivity filter |
Q42677283 | The open pore conformation of potassium channels |
Q34181912 | The pore helix is involved in stabilizing the open state of inwardly rectifying K+ channels |
Q34925261 | The search is on for the voltage sensor-to-gate coupling |
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Q22337264 | The voltage-gated potassium channels and their relatives |
Q47449784 | Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel. |
Q35954286 | Towards a structural view of gating in potassium channels |
Q28188178 | Two arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamily |
Q35808791 | Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel |
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