Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels

scientific article published on March 2001

Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0014-2999(01)00847-0
P698PubMed publication ID11274991

P2093author name stringDengler R
Bufler J
Mohammadi B
Krampfl K
Moschref H
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GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblastsQ77610176
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Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of actionQ42154486
Riluzole specifically blocks inactivated Na channels in myelinated nerve fibreQ43795777
Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on D-[3H]aspartate release from cultured cerebellar granule cellsQ45368638
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A reluctant gating mode of glycine receptor channels determines the time course of inhibitory miniature synaptic events in zebrafish hindbrain neurons.Q48487235
Impaired motor cortex inhibition in patients with amyotrophic lateral sclerosis. Evidence from paired transcranial magnetic stimulationQ48579454
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.Q51422993
Open channel block by physostigmine and procaine in embryonic-like nicotinic receptors of mouse muscle.Q51573583
The effect of riluzole in amyotrophic lateral sclerosis: a study with cortical stimulation.Q53920861
Desensitized states prolong GABAA channel responses to brief agonist pulses.Q54007822
Liquid filament switch for ultra-fast exchanges of solutions at excised patches of synaptic membrane of crayfish muscleQ68997543
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group IIQ71177245
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study GroupQ72759362
P433issue2-3
P407language of work or nameEnglishQ1860
P304page(s)135-140
P577publication date2001-03-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleInteraction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels
P478volume415

Reverse relations

cites work (P2860)
Q34104378A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade?
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Q45014668INaP underlies intrinsic spiking and rhythm generation in networks of cultured rat spinal cord neurons
Q40699967Interaction of high concentrations of riluzole with recombinant skeletal muscle sodium channels and adult-type nicotinic receptor channels
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