Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?

scientific article

Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0165-6147(02)02138-7
P698PubMed publication ID12413807
P5875ResearchGate publication ID11051150

P50authorHeinrich BetzQ1558372
P2093author name stringGábor Maksay
Bodo Laube
Rudolf Schemm
P2860cites workCrystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptorsQ27631812
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturationQ28296169
Distinct agonist- and antagonist-binding sites on the glycine receptorQ28326776
Activation of human alpha1 and alpha2 homomeric glycine receptors by taurine and GABAQ28354074
Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channelsQ28369450
Selective blocking effects of tropisetron and atropine on recombinant glycine receptorsQ28369836
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomersQ28378647
Glycine receptor beta subunits play a critical role in potentiation of glycine responses by ICS-205,930.Q31440487
Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamerQ33653057
Acute effects of ethanol on GABAA and glycine receptor functionQ33687185
Direct inhibition of glycine receptors by genistein, a tyrosine kinase inhibitorQ74238290
The glycine receptorQ34424350
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.Q34440513
Specific binding sites for alcohols and anesthetics on ligand-gated ion channelsQ34509821
Strychnine binding associated with glycine receptors of the central nervous systemQ34737634
Receptor classes and the transmitter-gated ion channelsQ35272725
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neuronesQ35871767
Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytesQ35873846
Potentiation of chloride responses to glycine by three 5-HT3 antagonists in rat spinal neuronesQ35874187
Enhancement of homomeric glycine receptor function by long-chain alcohols and anaestheticsQ35884602
Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding siteQ36858761
Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channelsQ40386612
Modulation of inhibitory and excitatory amino acid receptor ion channels by zincQ40391600
Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurineQ40769530
Ivermectin, an unconventional agonist of the glycine receptor chloride channelQ40816595
Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channelsQ40817864
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptorsQ40905699
Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit.Q40923579
The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gatingQ40976356
Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathwaysQ40997673
Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.Q41062053
Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brainQ41081995
The non-antiemetic uses of serotonin 5-HT3 receptor antagonists. Clinical pharmacology and therapeutic applicationsQ41331950
Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonistsQ41391248
Actions of 3-[2-phosphonomethyl[1,1-biphenyl]-3-yl]alanine (PMBA) on cloned glycine receptorsQ41932131
The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study.Q41962541
Inhibition of glycine currents by dextromethorphan in neurones dissociated from the guinea-pig nucleus tractus solitariiQ42122608
Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.Q42279580
Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA.Q42286099
Colchicine competitively antagonizes glycine receptors expressed in Xenopus oocytesQ42540772
Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region.Q43504216
Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor functionQ43603089
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neuronsQ43674620
Subunit-specific modulation of glycine receptors by neurosteroidsQ43719547
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibitionQ43770981
A novel domain of the inhibitory glycine receptor determining antagonist efficacies: further evidence for partial agonism resulting from self-inhibitionQ48127009
Cocaine decreases the glycine-induced Cl- current of acutely dissociated rat hippocampal neuronsQ48260522
Bidirectional allosteric modulation of strychnine-sensitive glycine receptors by tropeines and 5-HT3 serotonin receptor ligandsQ48307073
Development of glycinergic synaptic transmission to rat brain stem motoneuronsQ48348839
Glycine-receptor activation is required for receptor clustering in spinal neuronsQ48471322
Action of furosemide on GABA- and glycine currents in rat septal cholinergic neurons in cultureQ48557900
Release of endogenous Zn2+ from brain tissue during activityQ48682530
Interaction of thiocolchicoside with [3H]strychnine binding sites in rat spinal cord and brainstemQ48826835
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptorsQ49060987
Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channelsQ49161290
A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit.Q50803232
Acetylcholine receptor channel imaged in the open stateQ59067615
Modulation of GABAA and glycine receptors by chlormethiazoleQ67490510
Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptorQ69366000
Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neuronsQ72122157
Glycine receptors: a startling connectionQ72751014
Glycine receptor: light microscopic autoradiographic localization with [3H]strychnineQ72941178
P433issue11
P304page(s)519-527
P577publication date2002-11-01
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titleModulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?
P478volume23

Reverse relations

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