review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Heinrich Betz | Q1558372 |
P2093 | author name string | Gábor Maksay | |
Bodo Laube | |||
Rudolf Schemm | |||
P2860 | cites work | Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors | Q27631812 |
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation | Q28296169 | ||
Distinct agonist- and antagonist-binding sites on the glycine receptor | Q28326776 | ||
Activation of human alpha1 and alpha2 homomeric glycine receptors by taurine and GABA | Q28354074 | ||
Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channels | Q28369450 | ||
Selective blocking effects of tropisetron and atropine on recombinant glycine receptors | Q28369836 | ||
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers | Q28378647 | ||
Glycine receptor beta subunits play a critical role in potentiation of glycine responses by ICS-205,930. | Q31440487 | ||
Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer | Q33653057 | ||
Acute effects of ethanol on GABAA and glycine receptor function | Q33687185 | ||
Direct inhibition of glycine receptors by genistein, a tyrosine kinase inhibitor | Q74238290 | ||
The glycine receptor | Q34424350 | ||
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. | Q34440513 | ||
Specific binding sites for alcohols and anesthetics on ligand-gated ion channels | Q34509821 | ||
Strychnine binding associated with glycine receptors of the central nervous system | Q34737634 | ||
Receptor classes and the transmitter-gated ion channels | Q35272725 | ||
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones | Q35871767 | ||
Effects of inhalational general anaesthetics on native glycine receptors in rat medullary neurones and recombinant glycine receptors in Xenopus oocytes | Q35873846 | ||
Potentiation of chloride responses to glycine by three 5-HT3 antagonists in rat spinal neurones | Q35874187 | ||
Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics | Q35884602 | ||
Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site | Q36858761 | ||
Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels | Q40386612 | ||
Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc | Q40391600 | ||
Characterization of a glycine receptor domain that controls the binding and gating mechanisms of the beta-amino acid agonist, taurine | Q40769530 | ||
Ivermectin, an unconventional agonist of the glycine receptor chloride channel | Q40816595 | ||
Interaction of the neuroprotective drug riluzole with GABA(A) and glycine receptor channels | Q40817864 | ||
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors | Q40905699 | ||
Identification of an inhibitory Zn2+ binding site on the human glycine receptor alpha1 subunit. | Q40923579 | ||
The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating | Q40976356 | ||
Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways | Q40997673 | ||
Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. | Q41062053 | ||
Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain | Q41081995 | ||
The non-antiemetic uses of serotonin 5-HT3 receptor antagonists. Clinical pharmacology and therapeutic applications | Q41331950 | ||
Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonists | Q41391248 | ||
Actions of 3-[2-phosphonomethyl[1,1-biphenyl]-3-yl]alanine (PMBA) on cloned glycine receptors | Q41932131 | ||
The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study. | Q41962541 | ||
Inhibition of glycine currents by dextromethorphan in neurones dissociated from the guinea-pig nucleus tractus solitarii | Q42122608 | ||
Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator. | Q42279580 | ||
Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA. | Q42286099 | ||
Colchicine competitively antagonizes glycine receptors expressed in Xenopus oocytes | Q42540772 | ||
Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region. | Q43504216 | ||
Antagonism of inhalant and volatile anesthetic enhancement of glycine receptor function | Q43603089 | ||
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons | Q43674620 | ||
Subunit-specific modulation of glycine receptors by neurosteroids | Q43719547 | ||
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition | Q43770981 | ||
A novel domain of the inhibitory glycine receptor determining antagonist efficacies: further evidence for partial agonism resulting from self-inhibition | Q48127009 | ||
Cocaine decreases the glycine-induced Cl- current of acutely dissociated rat hippocampal neurons | Q48260522 | ||
Bidirectional allosteric modulation of strychnine-sensitive glycine receptors by tropeines and 5-HT3 serotonin receptor ligands | Q48307073 | ||
Development of glycinergic synaptic transmission to rat brain stem motoneurons | Q48348839 | ||
Glycine-receptor activation is required for receptor clustering in spinal neurons | Q48471322 | ||
Action of furosemide on GABA- and glycine currents in rat septal cholinergic neurons in culture | Q48557900 | ||
Release of endogenous Zn2+ from brain tissue during activity | Q48682530 | ||
Interaction of thiocolchicoside with [3H]strychnine binding sites in rat spinal cord and brainstem | Q48826835 | ||
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors | Q49060987 | ||
Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channels | Q49161290 | ||
A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit. | Q50803232 | ||
Acetylcholine receptor channel imaged in the open state | Q59067615 | ||
Modulation of GABAA and glycine receptors by chlormethiazole | Q67490510 | ||
Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptor | Q69366000 | ||
Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons | Q72122157 | ||
Glycine receptors: a startling connection | Q72751014 | ||
Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine | Q72941178 | ||
P433 | issue | 11 | |
P304 | page(s) | 519-527 | |
P577 | publication date | 2002-11-01 | |
P1433 | published in | Trends in Pharmacological Sciences | Q2451474 |
P1476 | title | Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses? | |
P478 | volume | 23 |
Q30459984 | 4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors |
Q43101508 | 4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance |
Q37112929 | A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue |
Q34715543 | A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists |
Q42910327 | A class of novel conjugates of substituted purine and Gly-AA-OBzl: Synthesis and evaluation of orally analgesic activity |
Q44832235 | A novel hyperekplexia-causing mutation in the pre-transmembrane segment 1 of the human glycine receptor alpha1 subunit reduces membrane expression and impairs gating by agonists. |
Q21145775 | A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors |
Q46938486 | Acute high-dose glycine attenuates mismatch negativity (MMN) in healthy human controls |
Q36364416 | Agonist-activated ion channels |
Q64060716 | Alfaxalone Causes Reduction of Glycinergic IPSCs, but Not Glutamatergic EPSCs, and Activates a Depolarizing Current in Rat Hypoglossal Motor Neurons |
Q30464018 | Allosteric modulation of glycine receptors |
Q34257782 | Atomistic insights into human Cys-loop receptors by solution NMR. |
Q34277790 | Binding interactions of antagonists with 5-hydroxytryptamine3A receptor models |
Q24658074 | Caffeine inhibition of ionotropic glycine receptors |
Q36072716 | Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. |
Q46599573 | Characterization of strychnine-sensitive glycine receptor in the intact frog retina: modulation by protein kinases |
Q33976839 | Chemistry and biology of terpene trilactones from Ginkgo biloba |
Q44774848 | Comparison of taurine- and glycine-induced conformational changes in the M2-M3 domain of the glycine receptor |
Q44639270 | Conserved High Affinity Ligand Binding and Membrane Association in the Native and Refolded Extracellular Domain of the Human Glycine Receptor α1-Subunit |
Q35197866 | Control of ethanol sensitivity of the glycine receptor α3 subunit by transmembrane 2, the intracellular splice cassette and C-terminal domains |
Q34419574 | Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors. |
Q27702217 | Crystal structure of human glycine receptor-α3 bound to antagonist strychnine |
Q46542399 | Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. |
Q44658571 | Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality |
Q36492400 | Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse. |
Q45030849 | Diversity of glycine receptors in the mouse retina: localization of the alpha2 subunit |
Q44585719 | Diversity of glycine receptors in the mouse retina: localization of the alpha3 subunit |
Q35551619 | Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain |
Q37954330 | From toxins targeting ligand gated ion channels to therapeutic molecules |
Q44530702 | Glycine facilitates transmitter release at developing synapses: a patch clamp study from Purkinje neurons of the newborn rat. |
Q37117223 | Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-beta-estradiol. |
Q44572995 | Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. |
Q30426940 | Glycine receptor mouse mutants: model systems for human hyperekplexia |
Q44516286 | Glycine receptors and glycinergic synaptic transmission in the deep cerebellar nuclei of the rat: a patch-clamp study |
Q36148124 | Glycine receptors contribute to hypnosis induced by ethanol |
Q36521927 | Glycine receptors: recent insights into their structural organization and functional diversity |
Q49011515 | Glycine release provoked by disturbed Na⁺, Na⁺ and Ca²⁺ homeostasis in cerebellar nerve endings: roles of Ca²⁺ channels, Na⁺/Ca²⁺ exchangers and GlyT2 transporter reversal |
Q48045943 | Glycinergic inhibition of BAT sympathetic premotor neurons in rostral raphe pallidus. |
Q48097419 | High-dose glycine inhibits the loudness dependence of the auditory evoked potential (LDAEP) in healthy humans |
Q46647562 | Hydrogen peroxide modulates synaptic transmission in ventral horn neurons of the rat spinal cord |
Q36418772 | Inhibitory glycine receptors: an update |
Q40648725 | Insights into the structural basis for zinc inhibition of the glycine receptor |
Q39808675 | Interaction of androsterone and progesterone with inhibitory ligand-gated ion channels: a patch clamp study. |
Q39722508 | Lack of positive allosteric modulation of mutated alpha(1)S267I glycine receptors by cannabinoids |
Q46517240 | Localization of glycine receptor alpha subunits on bipolar and amacrine cells in primate retina |
Q28686906 | Marine Toxins Targeting Ion Channels |
Q46943475 | Mechanisms of [(3)H]glycine release from mouse spinal cord synaptosomes selectively labeled through GLYT2 transporters |
Q37002640 | Mechanisms of homomeric alpha1 glycine receptor endocytosis |
Q36516836 | Modulating inhibitory ligand-gated ion channels |
Q34270612 | Molecular Determinants of Proton Modulation of Glycine Receptors |
Q37249405 | Molecular architecture of glycinergic synapses |
Q28115785 | Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors |
Q40220363 | Molecular determinants for G protein betagamma modulation of ionotropic glycine receptors. |
Q40419997 | Molecular determinants of glycine receptor alphabeta subunit sensitivities to Zn2+-mediated inhibition |
Q30391650 | Molecular requirements for ethanol differential allosteric modulation of glycine receptors based on selective Gbetagamma modulation |
Q34212824 | Molecular tuning of fast gating in pentameric ligand-gated ion channels |
Q28512079 | Nmf11 is a novel ENU-induced mutation in the mouse glycine receptor alpha 1 subunit |
Q39272135 | Paracetamol fails to positively modulate and directly activate chloride currents in human α1-glycine receptors |
Q37042321 | Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. |
Q34116031 | Pore conformations and gating mechanism of a Cys-loop receptor |
Q38298333 | Positive Modulation of the Glycine Receptor by Means of Glycine Receptor-Binding Aptamers |
Q39921211 | Positive allosteric modulatory effects of ajulemic acid at strychnine-sensitive glycine alpha1- and alpha1beta-receptors |
Q45105996 | Presynaptic glycine receptors on GABAergic terminals facilitate discharge of dopaminergic neurons in ventral tegmental area. |
Q48578242 | Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist-binding site |
Q44785529 | Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice. |
Q39897555 | Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives |
Q37395290 | Salicylate, an aspirin metabolite, specifically inhibits the current mediated by glycine receptors containing alpha1-subunits. |
Q41997810 | Selective potentiation of alpha 1 glycine receptors by ginkgolic acid. |
Q28576583 | Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens |
Q36248043 | Sites of alcohol and volatile anesthetic action on glycine receptors |
Q91260237 | Spinal gastrin releasing peptide receptor expressing interneurons are controlled by local phasic and tonic inhibition |
Q43261419 | Structural features of phenol derivatives determining potency for activation of chloride currents via alpha(1) homomeric and alpha(1)beta heteromeric glycine receptors |
Q38893053 | Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors |
Q46699075 | Structure-activity relationships of strychnine analogs at glycine receptors |
Q34413555 | Subunit rotation models activation of serotonin 5-HT3AB receptors by agonists |
Q44524221 | Taurine activates strychnine-sensitive glycine receptors in neurons freshly isolated from nucleus accumbens of young rats |
Q30486732 | The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels. |
Q48143336 | The Glycine Receptor-A Functionally Important Primary Brain Target of Ethanol. |
Q24297403 | The beta subunit determines the ligand binding properties of synaptic glycine receptors |
Q46402520 | The glycine transporter 1 inhibitor SSR504734 enhances working memory performance in a continuous delayed alternation task in C57BL/6 mice |
Q40191984 | Tropisetron modulation of the glycine receptor: femtomolar potentiation and a molecular determinant of inhibition |
Q42369938 | Zinc as a Neuromodulator in the Central Nervous System with a Focus on the Olfactory Bulb |
Q35055079 | Zinc modulation of glycine receptors |