Phosphate starvation: a novel signal that triggers ESX-5 secretion in Mycobacterium tuberculosis

scientific article published on 22 January 2016

Phosphate starvation: a novel signal that triggers ESX-5 secretion in Mycobacterium tuberculosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/MMI.13332
P932PMC publication ID4863468
P698PubMed publication ID26800324

P50authorAnna D. TischlerQ43013732
P2093author name stringSarah R Elliott
P2860cites workDeciphering the biology of Mycobacterium tuberculosis from the complete genome sequenceQ22122411
The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteriaQ24805932
Foamy macrophages and the progression of the human tuberculosis granulomaQ28255669
The phosphate regulon and bacterial virulence: a regulatory network connecting phosphate homeostasis and pathogenesisQ28267290
The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulenceQ28486347
Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulonQ28486821
Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosisQ28486852
ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress responseQ28486874
Secreted transcription factor controls Mycobacterium tuberculosis virulenceQ28487057
Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisitionQ28487139
Phosphate depletion: a novel trigger for Mycobacterium tuberculosis persistenceQ28487208
A mycobacterium ESX-1-secreted virulence factor with unique requirements for exportQ28487220
Molecular characterization of the mycobacterial SenX3-RegX3 two-component system: evidence for autoregulationQ28487370
Mutually dependent secretion of proteins required for mycobacterial virulence.Q28487400
Characterization of a Mycobacterium tuberculosis ESX-3 conditional mutant: essentiality and rescue by iron and zincQ28487459
Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion systemQ28941163
Mycobacterial PE/PPE proteins at the host-pathogen interfaceQ30399629
PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulenceQ33346189
Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistenceQ33383817
A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinumQ33570244
Mycobacterium tuberculosis wears what it eatsQ34089860
EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosisQ34115756
Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophagesQ34275913
Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimerQ34315690
Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretionQ34384191
Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosisQ35051702
Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis.Q35426482
The Roles and Regulation of Potassium in BacteriaQ35578284
Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape.Q35832097
Specific chaperones for the type VII protein secretion pathway.Q36234754
The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissueQ36350501
Mycobacterium tuberculosis requires phosphate-responsive gene regulation to resist host immunity.Q36506132
MprAB regulates the espA operon in Mycobacterium tuberculosis and modulates ESX-1 function and host cytokine response.Q36506250
Mycobacterium tuberculosis Resists Stress by Regulating PE19 ExpressionQ36631326
The ins and outs of Mycobacterium tuberculosis protein exportQ37970858
Tubercle bacilli rely on a type VII army for pathogenicityQ38031704
Take five - Type VII secretion systems of MycobacteriaQ38165002
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.Q39123504
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteriaQ39360723
Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activationQ39466150
ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activityQ42158023
Composition of the type VII secretion system membrane complex.Q45296085
Strong immunogenicity and cross-reactivity of Mycobacterium tuberculosis ESX-5 type VII secretion: encoded PE-PPE proteins predicts vaccine potentialQ45855190
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuationQ46837987
Elemental analysis of the Mycobacterium avium phagosome in Balb/c mouse macrophages.Q53625003
Elemental analysis of Mycobacterium avium-, Mycobacterium tuberculosis-, and Mycobacterium smegmatis-containing phagosomes indicates pathogen-induced microenvironments within the host cell's endosomal systemQ81300400
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium tuberculosisQ130971
P304page(s)510-526
P577publication date2016-01-22
P1433published inMolecular MicrobiologyQ6895967
P1476titlePhosphate starvation: a novel signal that triggers ESX-5 secretion in Mycobacterium tuberculosis
P478volume100

Reverse relations

cites work (P2860)
Q92659581Dual RNA-Seq of Mtb-Infected Macrophages In Vivo Reveals Ontologically Distinct Host-Pathogen Interactions
Q38963878ESX secretion systems: mycobacterial evolution to counter host immunity
Q63361584Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?
Q46254880Haem-iron plays a key role in the regulation of the Ess/type VII secretion system of Staphylococcus aureus RN6390.
Q39863834Inorganic Phosphate Limitation Modulates Capsular Polysaccharide Composition in Mycobacteria
Q26747272Modular Organization of the ESX-5 Secretion System in Mycobacterium tuberculosis
Q33911275Mycobacterium tuberculosis PhoY Proteins Promote Persister Formation by Mediating Pst/SenX3-RegX3 Phosphate Sensing.
Q55380367Mycobacterium tuberculosis Pst/SenX3-RegX3 Regulates Membrane Vesicle Production Independently of ESX-5 Activity.
Q93220808Mycobacterium tuberculosis Requires Regulation of ESX-5 Secretion for Virulence in Irgm1-Deficient Mice
Q90646017PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner
Q38815073Phosphate responsive regulation provides insights for ESX-5 function in Mycobacterium tuberculosis.
Q36372063Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence
Q46253295WhiB6 regulation of ESX-1 gene expression is controlled by a negative feedback loop in Mycobacterium marinum

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