Transition metals in control of gene expression

scientific article

Transition metals in control of gene expression is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P819ADS bibcode1993Sci...261..715O
P356DOI10.1126/SCIENCE.8342038
P698PubMed publication ID8342038

P2093author name stringT V O'Halloran
P433issue5122
P407language of work or nameEnglishQ1860
P921main subjecttransition metalQ19588
P304page(s)715-725
P577publication date1993-08-01
P1433published inScienceQ192864
P1476titleTransition metals in control of gene expression
P478volume261

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cites work (P2860)
Q37008124A Cu(I)-sensing ArsR family metal sensor protein with a relaxed metal selectivity profile.
Q27642378A Metal–Ligand-mediated Intersubunit Allosteric Switch in Related SmtB/ArsR Zinc Sensor Proteins
Q38785110A Three-Photon Active Organic Fluorophore for Deep Tissue Ratiometric Imaging of Intracellular Divalent Zinc
Q31039064A Turn-on Fluorescent Chemosensor for Zn(2+) Based on Quinoline in Aqueous Media
Q47724063A carboxyl-terminal Cys2/His2-type zinc-finger motif in DNA primase influences DNA content in Synechococcus PCC 7942.
Q27932889A dual role for zinc fingers in both DNA binding and zinc sensing by the Zap1 transcriptional activator.
Q39647385A highly selective OFF–ON fluorescent sensor for zinc in aqueous solution and living cells
Q44090741A nickel-cobalt-sensing ArsR-SmtB family repressor. Contributions of cytosol and effector binding sites to metal selectivity
Q50470140A novel chemosensor with visible light excitability for sensing Zn2+ in physiological medium and in HeLa cells.
Q42632108A novel gene cluster including the Rhodococcus rhodochrous J1 nhlBA genes encoding a low molecular mass nitrile hydratase (L-NHase) induced by its reaction product
Q36800457A novel iron-regulated metal transporter from plants identified by functional expression in yeast.
Q48044071A novel protein with DNA binding activity from tobacco chloroplast nucleoids.
Q48071569A pAO1-encoded molybdopterin cofactor gene (moaA) of Arthrobacter nicotinovorans: characterization and site-directed mutagenesis of the encoded protein
Q58105485A ratiometric fluorescent core-shell nanoprobe for sensing and imaging of zinc(II) in living cell and zebrafish
Q35626546A rubrerythrin operon and nigerythrin gene in Desulfovibrio vulgaris (Hildenborough).
Q41626547A systems view of haloarchaeal strategies to withstand stress from transition metals
Q36016794A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc
Q46960058A theoretical study of zinc(II) interactions with amino acid models and peptide fragments
Q35918279A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes
Q43759774Activation of ADAM 12 protease by copper
Q95719585Activation of silent gal genes in the lac-gal regulon of Streptococcus thermophilus
Q46290305Affinity purification of plasmid DNA by temperature-triggered precipitation
Q92131339Allosteric control of metal-responsive transcriptional regulators in bacteria
Q38955294An overview of the biological metal uptake pathways in Pseudomonas aeruginosa.
Q36279049Application of immobilized metal affinity chromatography in proteomics
Q43324564Assessment of mercury(II) bioavailability using a bioluminescent bacterial biosensor: practical and theoretical challenges.
Q36557213Autoactivation by a Candida glabrata copper metalloregulatory transcription factor requires critical minor groove interactions
Q40536101Bacterial resistance mechanisms for heavy metals of environmental concern
Q41305858Bacterial resistances to toxic metal ions--a review
Q77161280Binding and the nature of Cu(II) ion interaction with nucleosomes
Q47883907Bioinorganic chemistry and drug design: here comes zinc again
Q34243472Biological consequences of zinc deficiency in the pathomechanisms of selected diseases
Q39837783CadC, the transcriptional regulatory protein of the cadmium resistance system of Staphylococcus aureus plasmid pI258
Q43891566Cadmium-induced DNA synthesis and cell proliferation in macrophages: the role of intracellular calcium and signal transduction mechanisms
Q33992161Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR.
Q35204289Cell-density-dependent sensitivity of a mer-lux bioassay.
Q41841616Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells
Q27932968Characterization of a unique protein component of yeast RNase MRP: an RNA-binding protein with a zinc-cluster domain
Q80546586Chiral CE of aromatic amino acids by ligand-exchange with zinc(II)-L-lysine complex
Q33649794Clioquinol inhibits zinc-triggered caspase activation in the hippocampal CA1 region of a global ischemic gerbil model
Q33548215Cobalt proteins
Q52536197Cobalt-dependent transcriptional switching by a dual-effector MerR-like protein regulates a cobalt-exporting variant CPx-type ATPase.
Q42185460Comparative study of the different mechanisms for zinc ion stress sensing in two cyanobacterial strains, Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.
Q50732189Computational design of zinc-ion-responsive two-photon fluorescent probes with conjugated multi-structures.
Q39869177Condensation Product of Phenylalanine and Salicylaldehyde: Fluorescent Sensor for Zn(2.).
Q41892840Conformational and thermodynamic hallmarks of DNA operator site specificity in the copper sensitive operon repressor from Streptomyces lividans
Q30360194Conformational studies of the manganese transport regulator (MntR) from Bacillus subtilis using deuterium exchange mass spectrometry.
Q35158093Construction of a self-luminescent cyanobacterial bioreporter that detects a broad range of bioavailable heavy metals in aquatic environments.
Q88876742Convergent Use of Heptacoordination for Cation Selectivity by RNA and Protein Metalloregulators
Q35005569Coordination chemistry of bacterial metal transport and sensing
Q40356707Copper and nickel bind via two distinct kinetic mechanisms to a CsoR metalloregulator
Q36676521Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster
Q27675582Crystal Structure of the Zinc-Dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-Bound State
Q27642396Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor
Q27742471Crystal structures of the copper and nickel complexes of RNase A: metal-induced interprotein interactions and identification of a novel copper binding motif
Q100316448CueR activates transcription through a DNA distortion mechanism
Q38317199DNA distortion mechanism for transcriptional activation by ZntR, a Zn(II)-responsive MerR homologue in Escherichia coli
Q34464580Design of clinically useful iron(III)-selective chelators
Q37471045Differential display of intestinal mRNAs regulated by dietary zinc
Q42549649Differential gene expression in response to exposure to antimycobacterial agents and other stress conditions among seven Mycobacterium tuberculosis whiB-like genes
Q44475448Differential regulation of genes encoding manganese peroxidase (MnP) in the basidiomycete Ceriporiopsis subvermispora
Q41706945Early copper-induced leakage of K(+) from Arabidopsis seedlings is mediated by ion channels and coupled to citrate efflux
Q28378867Effect of non-toxic mercury, zinc or cadmium pretreatment on the capacity of human monocytes to undergo lipopolysaccharide-induced activation
Q52532763Effect of redox conditions on the DNA-binding efficiency of the retinoic acid receptor zinc-finger.
Q39303413Effect of zinc deprivation on the lipid metabolism of budding yeast
Q39248566Effects of exogenous zinc on the cellular zinc distribution and cell cycle of A549 cells
Q36800994Electron probe X-ray microanalysis of the elemental composition of the pineal gland of young adults and aged rats
Q64383237Excess copper and ceruloplasmin biosynthesis in long-term cultured hepatocytes from Long-Evans Cinnamon (LEC) rats, a model of Wilson disease
Q36136599Expression of the zinc finger gene EVI-1 in ovarian and other cancers
Q57996311Expression, Purification, and Metal Binding Properties of the N-terminal Domain from the Wilson Disease Putative Copper-transporting ATPase (ATP7B)
Q28476065Fast growth increases the selective advantage of a mutation arising recurrently during evolution under metal limitation
Q38256791FeON-FeOFF: the Helicobacter pylori Fur regulator commutates iron-responsive transcription by discriminative readout of opposed DNA grooves
Q35008922Fluorescence lifetime imaging of physiological free Cu(II) levels in live cells with a Cu(II)-selective carbonic anhydrase-based biosensor
Q58730326Fluorescent Zn Chemosensor Mediated by a 1,8-Naphthyridine Derivative and It's Photophysical Properties
Q36697295Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of Plasmodium falciparum
Q72243628Functional domains of the Escherichia coli ferric uptake regulator protein (Fur)
Q24548476Genome of the extremely radiation-resistant bacterium Deinococcus radiodurans viewed from the perspective of comparative genomics
Q77993164Geographical variation in rate of schizophrenia in rural Ireland by place at birth vs place at onset
Q28486821Global analysis of the Mycobacterium tuberculosis Zur (FurB) regulon
Q42545982HgCl2-induced interleukin-4 gene expression in T cells involves a protein kinase C-dependent calcium influx through L-type calcium channels
Q50278911Highly photostable zinc selective molecular marker bearing flexible pivotal unit: opto-fluorescence enhancement effect and imaging applications in living systems.
Q57204410Highly water-soluble BODIPY-based fluorescent probes for sensitive fluorescent sensing of zinc(ii)
Q41551899IP6: a novel anti-cancer agent
Q34718541Identification of a copper-inducible promoter for use in ectopic expression in the fungal pathogen Histoplasma capsulatum
Q39095806In vitro protection by pyruvate against cadmium-induced cytotoxicity in hippocampal HT-22 cells
Q28584119Induction of cellular prion protein gene expression by copper in neurons
Q38358822Induction of ferritin synthesis in cells infected with Mengo virus
Q40633539Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+
Q27666944Insights into Metalloregulation by M-box Riboswitch RNAs via Structural Analysis of Manganese-Bound Complexes
Q41170225Intermediate steps in cellular iron uptake from transferrin. II. A cytoplasmic pool of iron is released from cultured cells via temperature-dependent mechanical wounding
Q39494943Iron reductase for magnetite synthesis in the magnetotactic bacterium Magnetospirillum magnetotacticum.
Q27936505Iron-regulated DNA binding by the AFT1 protein controls the iron regulon in yeast.
Q36692145Isolation and characterization of mosquito ferritin and cloning of a cDNA that encodes one subunit
Q40837015L-type Ca(2+) channel-mediated Zn(2+) toxicity and modulation by ZnT-1 in PC12 cells
Q34990695Manganese: elemental defence for a life with oxygen
Q38504074Mapping essential domains of Mycobacterium smegmatis WhmD: insights into WhiB structure and function
Q34406903Maternally-derived zinc transporters ZIP6 and ZIP10 drive the mammalian oocyte-to-egg transition
Q48567839Measurement of intracellular free zinc in living cortical neurons: routes of entry
Q40456801Mechanisms of metalloregulation of an anion-translocating ATPase
Q44519078Membrane-permeant chelators can attenuate Zn2+-induced cortical neuronal death
Q78653720Mercury in vaccines--reassuring news
Q39498019Mercury resistance in Bacillus cereus RC607: transcriptional organization and two new open reading frames
Q52047728Mercury-reactive lymphocytes in peripheral blood are not a marker for dental amalgam associated disease.
Q36922597Metal binding studies and EPR spectroscopy of the manganese transport regulator MntR
Q39312476Metal homeostasis in bacteria: the role of ArsR-SmtB family of transcriptional repressors in combating varying metal concentrations in the environment
Q41838123Metal- and DNA-binding properties and mutational analysis of the transcription activating factor, B, of coliphage 186: a prokaryotic C4 zinc-finger protein
Q40488678Metalloenzymes, Structural Motifs, and Inorganic Models
Q73230395Metalloprotein analysis by capillary isoelectric focusing
Q34997092Metalloproteins and metal sensing
Q36268551Metalloregulator CueR biases RNA polymerase's kinetic sampling of dead-end or open complex to repress or activate transcription
Q53970053MntR modulates expression of the PerR regulon and superoxide resistance in Staphylococcus aureus through control of manganese uptake.
Q40491992Modulation of iron on mitochondrial aconitase expression in human prostatic carcinoma cells
Q40473960Molecular Regulation of Heme Biosynthesis in Higher Vertebrates
Q24609696Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein
Q34932216Molecular dynamics study of zinc binding to cysteines in a peptide mimic of the alcohol dehydrogenase structural zinc site.
Q44509256Molecular simulations to determine the chelating mechanisms of various metal ions to the His-tag motif: a preliminary study
Q48456912Normalization of zinc intake enhances neurological retrieval of patients suffering from ischemic strokes
Q28237919Nutrition for brain recovery after ischemic stroke: an added value to rehabilitation
Q45145749On the competition for available zinc
Q38330221Oxidation of guanines in the iron-responsive element RNA: similar structures from chemical modification and recent NMR studies
Q34931641Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange
Q34007737PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus
Q72054812Phorbol Esters Stimulate Non-transferrin Iron Uptake by K562 Cells
Q43734045Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.
Q43625444Physical interaction of CcmC with heme and the heme chaperone CcmE during cytochrome c maturation
Q71860402Post-transcriptional regulation of plant ferritin accumulation in response to iron as observed in the maize mutant ys1
Q30619545Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks
Q38944584ROS-mediated cytotoxic effect of copper(II) hydrazone complexes against human glioma cells.
Q52526577Redox modulation of iron regulatory proteins by peroxynitrite.
Q54276484Redox-dependent DNA distortion in a SoxR protein-promoter complex studied using fluorescent probes.
Q41625191Regulation of bacterial gene expression by metals.
Q36572865Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper.
Q29346706Regulation of the Bacillus subtilis fur and perR genes by PerR: not all members of the PerR regulon are peroxide inducible
Q77577918Repeated fed-batch operations for microbial detoxification of mercury using wild-type and recombinant mercury-resistant bacteria
Q58068517Responsive polymer-based multicolor fluorescent probes for temperature and Zn2+ ions in aqueous media
Q38261004Review: Zinc's functional significance in the vertebrate retina
Q79107845Role and regulation of the superoxide dismutases of Staphylococcus aureus
Q40324092Role of V protein RNA binding in inhibition of measles virus minigenome replication
Q71823780Selective Oxidative Modification and Affinity Cleavage of Pigeon Liver Malic Enzyme by the Cu2+-Ascorbate System
Q35783590Simulations of allosteric motions in the zinc sensor CzrA.
Q27001348Single-molecule dynamics and mechanisms of metalloregulators and metallochaperones
Q37281924Single-molecule study of metalloregulator CueR-DNA interactions using engineered Holliday junctions.
Q24295147Splicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleus
Q27690190Structural analysis and insight into metal-ion activation of the iron-dependent regulator from Thermoplasma acidophilum
Q35050242Structural and functional insights of Wilson disease copper-transporting ATPase
Q34915683Structural elements of metal selectivity in metal sensor proteins.
Q27702046Structural insights into conformational switching in the copper metalloregulator CsoR from Streptomyces lividans
Q35813681Structurally Characterized Zn2+ Selective Ratiometric Fluorescence Probe in 100 % Water for HeLa Cell Imaging: Experimental and Computational Studies
Q42605158Structure analysis of a class II transposon encoding the mercury resistance of the Gram-positive Bacterium bacillus megaterium MB1, a strain isolated from minamata bay, Japan
Q39006966Structure and Differential Expression of two Maize Ferritin Genes in Response to Iron and Abscisic Acid
Q24562918Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae
Q50222393Synthesis and sensor activity of a PET-based 1,8-naphthalimide Probe for Zn(2+) and pH determination
Q47304365Synthetic biology for microbial heavy metal biosensors
Q34355607Tackling metal regulation and transport at the single-molecule level
Q35164001The SmtB/ArsR family of metalloregulatory transcriptional repressors: Structural insights into prokaryotic metal resistance
Q34348941The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene
Q29346529The Zur regulon of Corynebacterium glutamicum ATCC 13032.
Q24315696The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation
Q38047152The complex architecture of mycobacterial promoters.
Q42829334The mammalian transferrin-independent iron transport system may involve a surface ferrireductase activity
Q41608115The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
Q33891435The role of the membrane-bound tumour antigen, melanotransferrin (p97), in iron uptake by the human malignant melanoma cell
Q26860290The roles of metal ions in regulation by riboswitches
Q33786918The yin and yang of nitric oxide: reflections on the physiology and pathophysiology of NO.
Q29346569The zinc-responsive regulon of Neisseria meningitidis comprises 17 genes under control of a Zur element
Q24648949The zntA gene of Escherichia coli encodes a Zn(II)-translocating P-type ATPase
Q33994441Tissue-specific gene expression identifies a gene in the lysogenic phage Gifsy-1 that affects Salmonella enterica serovar typhimurium survival in Peyer's patches.
Q35183885Transcriptional involvement in neurotoxicity
Q28203407Transition Metal Speciation in the Cell: Insights from the Chemistry of Metal Ion Receptors
Q57365603Ultra metal ions and pH sensing characteristics of thermoresponsive luminescent electrospun nanofibers prepared from poly(HPBO-co-NIPAAm-co-SA)
Q36350886Ultrastructural and morphometrical changes of mice ovaries following experimentally induced copper poisoning.
Q39547650Use of heme-protein complexes by the Yersinia enterocolitica HemR receptor: histidine residues are essential for receptor function.
Q28646226Why reversing the sequence of the alpha domain of human metallothionein-2 does not change its metal-binding and folding characteristics
Q41358072X-ray crystal structures of the pheromone-binding domains of two quorum-hindered transcription factors, YenR of Yersinia enterocolitica and CepR2 of Burkholderia cenocepacia.
Q53476327X-ray structurally characterized sensors for ratiometric detection of Zn(2+) and Al(3+) in human breast cancer cells (MCF7): development of a binary logic gate as a molecular switch.
Q73369561Zinc and Alzheimer's disease: is there a direct link?
Q28374397Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1
Q34520167Zinc and disease of the brain
Q27013656Zinc and neurogenesis: making new neurons from development to adulthood
Q33928055Zinc and the immune system
Q39380426Zinc at cytotoxic concentrations affects posttranscriptional events of gene expression in cancer cells
Q39123752Zinc at sub-cytotoxic concentrations induces heme oxygenase-1 expression in human cancer cells
Q34076166Zinc availability regulates exit from meiosis in maturing mammalian oocytes
Q70830917Zinc binding in proteins and solution: a simple but accurate nonbonded representation
Q34462187Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression
Q27937786Zinc fingers can act as Zn2+ sensors to regulate transcriptional activation domain function
Q52702579Zinc inhibition of pyruvate kinase of M-type isozyme.
Q36980255Zinc modulation of calcium activity at the photoreceptor terminal: a calcium imaging study.
Q34734112Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis
Q44219027Zinc translocation accelerates infarction after mild transient focal ischemia.
Q39184979Zinc(II) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells.
Q27733354Zinc- and iron-rubredoxins from Clostridium pasteurianum at atomic resolution: a high-precision model of a ZnS4 coordination unit in a protein
Q36969045Zinc-mediated feedback at the synaptic terminals of vertebrate photoreceptors
Q30333096Zn(II) metabolism in prokaryotes.

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