Sildenafil has no effect on portal pressure but lowers arterial pressure in patients with compensated cirrhosis

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Sildenafil has no effect on portal pressure but lowers arterial pressure in patients with compensated cirrhosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CGH.2010.01.017
P932PMC publication ID2879450
P698PubMed publication ID20144739
P5875ResearchGate publication ID41419135

P2093author name stringPuneeta Tandon
Guadalupe Garcia-Tsao
Roberto J Groszmann
Michael Tal
Irteza Inayat
Marcelo Spector
Martha Shea
P2860cites workPotency, selectivity, and consequences of nonselectivity of PDE inhibitionQ28269129
Evidence for expression and function of phosphodiesterase type 5 (PDE-V) in rat resistance arteriesQ28345798
Increased phosphodiesterase-5 expression is involved in the decreased vasodilator response to nitric oxide in cirrhotic rat liversQ28582476
Hepatic vein pressure gradient reduction and prevention of variceal bleeding in cirrhosis: a systematic reviewQ33263463
Molecular mechanism of cGMP-mediated smooth muscle relaxationQ33980649
Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis.Q34469981
Molecular biology and pharmacology of PDE-5-inhibitor therapy for erectile dysfunction.Q35569263
The hepatic venous pressure gradient: anything worth doing should be done rightQ35651680
Sildenafil does not influence hepatic venous pressure gradient in patients with cirrhosisQ37386601
Rapid nitric oxide-induced desensitization of the cGMP response is caused by increased activity of phosphodiesterase type 5 paralleled by phosphorylation of the enzymeQ42951390
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.Q44385938
Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites.Q45197565
Acute administration of sildenafil enhances hepatic cyclic guanosine monophosphate production and reduces hepatic sinusoid resistance in cirrhotic patientsQ46480928
Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver -- results of a pilot studyQ46879609
Ca/CaM-stimulated and cGMP-specific phosphodiesterases in vascular and non-vascular tissues.Q48828424
Low-dose midazolam sedation: an option for patients undergoing serial hepatic venous pressure measurements.Q51091239
Relaxation induced by cGMP phosphodiesterase inhibitors sildenafil and zaprinast in human vesselsQ73198479
Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic ratsQ77355535
Pharmacological reduction of portal pressure and long-term risk of first variceal bleeding in patients with cirrhosisQ82853308
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)546-549
P577publication date2010-02-06
P1433published inClinical Gastroenterology and HepatologyQ5133759
P1476titleSildenafil has no effect on portal pressure but lowers arterial pressure in patients with compensated cirrhosis
P478volume8