Relaxation induced by cGMP phosphodiesterase inhibitors sildenafil and zaprinast in human vessels

scientific article published on 01 October 2000

Relaxation induced by cGMP phosphodiesterase inhibitors sildenafil and zaprinast in human vessels is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0003-4975(00)01914-7
P698PubMed publication ID11081893

P50authorPascual MedinaQ44272030
P2093author name stringG Segarra
J M Vila
S Lluch
M Aldasoro
E Otero
J B Martínez-León
P2860cites workEffects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymesQ74582058
Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitroQ74607760
Cyclic guanosine monophosphate as a mediator of vasodilationQ24623087
Cyclic nucleotide phosphodiesterases: functional implications of multiple isoformsQ29619683
Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonistQ33855125
Clinical pharmacology, physiology and pathophysiology of superficial veins--1.Q34346245
Use of sildenafil (Viagra) in patients with cardiovascular disease. Technology and Practice Executive CommitteeQ34486937
Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study GroupQ34747116
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitorsQ37876904
Intracellular cyclic GMP receptor proteinsQ40485121
Pleiotropic regulation of vascular smooth muscle tone by cyclic GMP-dependent protein kinaseQ40764514
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivoQ42562507
Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart diseaseQ42595070
Effects of sildenafil citrate on human hemodynamics.Q54102642
Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aortaQ70142026
Sildenafil, a novel effective oral therapy for male erectile dysfunctionQ71547678
Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging StudyQ72641848
Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitroQ73457349
Does severity of ischemic coronary disease correlate with erectile function?Q73744280
Effects of sildenafil on human penile blood vesselsQ74234057
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1327-1331
P577publication date2000-10-01
P1433published inThe Annals of Thoracic SurgeryQ1939819
P1476titleRelaxation induced by cGMP phosphodiesterase inhibitors sildenafil and zaprinast in human vessels
P478volume70

Reverse relations

cites work (P2860)
Q24798647Coronary artery flow reserve in diabetics with erectile dysfunction using sildenafil
Q40594131Effect of sildenafil (Viagra®) on cerebral blood flow velocity: a pilot study
Q43264465Inhibition of neuroeffector transmission in human vas deferens by sildenafil
Q43915744Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery
Q46833811Relaxant effect of sildenafil in the rabbit basilar artery
Q44111212Relaxation induced by milrinone and rolipram in human penile arteries and veins.
Q43962913Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta
Q79991337Sildenafil decreased pulmonary arterial pressure but may have exacerbated portal hypertension in a patient with cirrhosis and portopulmonary hypertension
Q37472745Sildenafil does not enhance but rather attenuates vasorelaxant effects of antidiabetic agents
Q40841503Sildenafil has no effect on portal pressure but lowers arterial pressure in patients with compensated cirrhosis
Q43786525Sildenafil inhibits agonist-evoked rat uterine contractility: influence of guanylyl cyclase inhibition
Q44318890The effect of chronic renal failure on phosphodiesterase inhibitor-induced relaxation responses in rabbit cavernosal strips

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