Evaluation of a human monocytic cell line THP-1 model for assay of the intracellular activities of antimicrobial agents against Legionella pneumophila

scientific article

Evaluation of a human monocytic cell line THP-1 model for assay of the intracellular activities of antimicrobial agents against Legionella pneumophila is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/JAC/46.4.589
P698PubMed publication ID11020257

P2093author name stringYamamoto H
Kaku M
Hara T
Shimada J
Takemura H
Shoji Y
Ikejima H
Kanemitsu K
Kunishima H
Terakubo S
P2860cites workThe in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella sppQ28263396
Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)Q28276146
Antimicrobial activities of benzoxazinorifamycin (KRM-1648) and clarithromycin against Mycobacterium avium-intracellulare complex within murine peritoneal macrophages, human macrophage-like cells and human alveolar epithelial cellsQ28374518
In vitro activity of sparfloxacin (CI-978; AT-4140) for clinical Legionella isolates, pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumoniaQ35280841
Inhibition of Legionella pneumophila multiplication within human macrophages by antimicrobial agentsQ35575694
Susceptibility of Legionella pneumophila to ofloxacin in vitro and in experimental Legionella pneumonia in guinea pigsQ39834038
Activity of azithromycin, clarithromycin, roxithromycin, dirithromycin, quinupristin/dalfopristin and erythromycin against Legionella species by intracellular susceptibility testing in HL-60 cellsQ41052699
Comparative study of the bactericidal activity of ampicillin/sulbactam and erythromycin against intracellular Legionella pneumophila.Q41545734
A simple method for counting adherent cells: application to cultured human monocytes, macrophages and multinucleated giant cells.Q50930433
Legionella pneumophilaQ58419050
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectLegionella pneumophilaQ147885
P304page(s)589-594
P577publication date2000-10-01
P1433published inJournal of Antimicrobial ChemotherapyQ6294770
P1476titleEvaluation of a human monocytic cell line THP-1 model for assay of the intracellular activities of antimicrobial agents against Legionella pneumophila
P478volume46

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cites work (P2860)
Q40066419Differential expression of virulence genes in Legionella pneumophila growing in Acanthamoeba and human monocytes.
Q28533449Exploring anti-bacterial compounds against intracellular Legionella
Q58573611Influence of the protein kinase C activator phorbol myristate acetate on the intracellular activity of antibiotics against hemin- and menadione-auxotrophic small-colony variant mutants of Staphylococcus aureus and their wild-type parental strain in h
Q39352419Pharmacodynamic evaluation of the activity of antibiotics against hemin- and menadione-dependent small-colony variants of Staphylococcus aureus in models of extracellular (broth) and intracellular (THP-1 monocytes) infections
Q24798106Screening of compounds toxicity against human Monocytic cell line-THP-1 by flow cytometry

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