Exploring anti-bacterial compounds against intracellular Legionella

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Exploring anti-bacterial compounds against intracellular Legionella is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...874813H
P356DOI10.1371/JOURNAL.PONE.0074813
P932PMC publication ID3772892
P698PubMed publication ID24058631
P5875ResearchGate publication ID256931575

P50authorHubert HilbiQ58981515
Thierry SoldatiQ40295458
Hajer Ouertatani-SakouhiQ43376212
P2093author name stringNikolaus Ackermann
Christian Hedberg
Pierre Cosson
Hajer Ouertatani-Sakouhi
Sébastien Kicka
Christopher F Harrison
Valentin Trofimov
Kathrin Berschl
P2860cites workLegionella spp. outdoors: colonization, communication and persistence.Q50913097
Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and MQ57006811
Intracellular multiplication and human macrophage killing byLegionella pneumophilaare inhibited by conjugal components of IncQ plasmid RSF1010Q62673794
The Legionella pneumophila phosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuoleQ81730696
Insights into Structural Network Responsible for Oligomerization and Activity of Bacterial Virulence Regulator Caseinolytic Protease P (ClpP) ProteinQ27676956
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysQ28145712
A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hitQ28479211
Drugs for bad bugs: confronting the challenges of antibacterial discoveryQ29547723
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ERQ29615171
Dynasore, a cell-permeable inhibitor of dynaminQ29619881
Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuoleQ33243973
The ClpP protease homologue is required for the transmission traits and cell division of the pathogen Legionella pneumophilaQ33532315
Molecular pathogenesis of infections caused by Legionella pneumophilaQ33825611
Inhibition of retrograde transport protects mice from lethal ricin challengeQ34022109
Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisoneQ34613387
Ras/Raf signalling and emerging pharmacotherapeutic targetsQ34660771
Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hostsQ34969920
Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampinQ35202108
Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansionQ35202685
Inhibition of Legionella pneumophila multiplication within human macrophages by antimicrobial agentsQ35575694
Subversion of membrane transport pathways by vacuolar pathogensQ35621027
Antimicrobial Susceptibility of Intracellular Legionella pneumophilaQ35672355
Microorganisms resistant to free-living amoebaeQ35745838
Dictyostelium as host model for pathogenesisQ36023742
The biology and future prospects of antivirulence therapiesQ36397902
Legionella: macrolides or quinolones?Q36466638
Exploiting quorum sensing to confuse bacterial pathogensQ36667376
Legionella pneumophila - a human pathogen that co-evolved with fresh water protozoa.Q36694141
Targeting virulence: a new paradigm for antimicrobial therapyQ36914994
The Legionella pneumophila replication vacuole: making a cosy niche inside host cellsQ37326393
Legionella, protozoa, and biofilms: interactions within complex microbial systems.Q37443935
Modulation of Host Cell Function byLegionella pneumophilaType IV EffectorsQ37798551
Secretive bacterial pathogens and the secretory pathway.Q37849309
Tuberculosis pathogenesis and immunityQ37952831
Pathogen vacuole purification from legionella-infected amoeba and macrophagesQ39245223
Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity designQ39476739
The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellaniiQ39496795
Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cellsQ39519213
Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophilaQ39780962
The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE.Q39914102
The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA.Q40110647
Validation of the essential ClpP protease in Mycobacterium tuberculosis as a novel drug targetQ40596851
Evaluation of a human monocytic cell line THP-1 model for assay of the intracellular activities of antimicrobial agents against Legionella pneumophilaQ40851098
Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic cultureQ41826297
New life for an old drug: the anthelmintic drug niclosamide inhibits Pseudomonas aeruginosa quorum sensingQ42790739
Acanthamoeba polyphaga resuscitates viable non-culturable Legionella pneumophila after disinfection.Q43347182
Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuoleQ43515773
Sequence and genome context analysis of a new molecular class D beta-lactamase gene from Legionella pneumophila.Q44121022
The mechanism of caseinolytic protease (ClpP) inhibitionQ44175173
Interactions of legionella effector proteins with host phosphoinositide lipidsQ44977588
Analysis of legionella infection by flow cytometryQ45760946
Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infectionQ46473864
Bioactive natural and semisynthetic latrunculinsQ46961520
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)e74813
P577publication date2013-01-01
P1433published inPLOS OneQ564954
P1476titleExploring anti-bacterial compounds against intracellular Legionella
P478volume8

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cites work (P2860)
Q52350987Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection.
Q52676415Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets.
Q90176619Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models
Q40126421Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model
Q37622087Intra-Species and Inter-Kingdom Signaling of Legionella pneumophila.
Q37142298Metabolism of myo-Inositol by Legionella pneumophila Promotes Infection of Amoebae and Macrophages
Q41577063Potent antimicrobial peptides against Legionella pneumophila and its environmental host, Acanthamoeba castellanii
Q47736263Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity
Q38156244The natural alternative: protozoa as cellular models for Legionella infection
Q36381839Thymoquinone (TQ) inhibits the replication of intracellular Mycobacterium tuberculosis in macrophages and modulates nitric oxide production
Q47573828Towards re-purposing BH3-mimetics in Legionella and viral infections

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