| P50 | author | Marco Pagni | Q47097366 |
| | Leonardo Scapozza | Q58448519 |
| P2093 | author name string | Thierry Soldati | |
| | Pierre Cosson | |
| | Hubert Hilbi | |
| | Nabil Hanna | |
| | Sébastien Kicka | |
| | Christopher Harrison | |
| | Gianpaolo Chiriano | |
| | Agata Kranjc | |
| | Valentin Trofimov | |
| | Hajer Ouertatani Sakouhi | |
| | Jahn Nitschke | |
| P2860 | cites work | The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection | Q61453633 |
| | Molecular basis for the polyamine-ompF porin interactions: inhibitor and mutant studies | Q73590585 |
| | Dictyostelium discoideum: a model host to measure bacterial virulence | Q83162103 |
| | Clinical Diagnosis of Legionnaire's Disease: Six Characteristic Clinical Predictors | Q85410804 |
| | How academic labs can approach the drug discovery process as a way to synergize with big pharma | Q86889793 |
| | Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen | Q87202121 |
| | Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis | Q92043792 |
| | Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel | Q24602501 |
| | Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors | Q26781334 |
| | Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine | Q27628650 |
| | The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product | Q27639134 |
| | Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors | Q27657102 |
| | Design of O -Acetylserine Sulfhydrylase Inhibitors by Mimicking Nature | Q27658287 |
| | Structural basis for human monoglyceride lipase inhibition | Q27658438 |
| | Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution | Q27666922 |
| | The crystal structure of a voltage-gated sodium channel | Q27670752 |
| | Methicillin-resistant Staphylococcus aureus (MRSA) Pyruvate Kinase as a Target for Bis-indole Alkaloids with Antibacterial Activities | Q27675245 |
| | Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings | Q27861111 |
| | Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake | Q27887122 |
| | A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases | Q28140411 |
| | Crystal structure of a mammalian voltage-dependent Shaker family K+ channel | Q28260421 |
| | Navigating chemical space for biology and medicine | Q28298611 |
| | Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening | Q28487571 |
| | Exploring anti-bacterial compounds against intracellular Legionella | Q28533449 |
| | Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system | Q28539402 |
| | Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment | Q28543551 |
| | ZINC 15--Ligand Discovery for Everyone | Q28607096 |
| | Virtual screening: an in silico tool for interlacing the chemical universe with the proteome. | Q30366496 |
| | Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions | Q30387813 |
| | Amoebae-resisting bacteria isolated from human nasal swabs by amoebal coculture | Q30925319 |
| | LINGO, an efficient holographic text based method to calculate biophysical properties and intermolecular similarities | Q30986370 |
| | ChemGPS-NP: tuned for navigation in biologically relevant chemical space | Q33282287 |
| | Scaffold composition and biological relevance of screening libraries. | Q33291102 |
| | ChemGPS-NP(Web): chemical space navigation online | Q33392980 |
| | Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner | Q33611027 |
| | Amoebae as training grounds for intracellular bacterial pathogens | Q33722169 |
| | In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA. | Q40145483 |
| | Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells | Q40410781 |
| | Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays | Q41425604 |
| | Save Antibiotics: a call for action of the World Alliance Against Antibiotic Resistance (WAAAR). | Q42353812 |
| | A marine natural product inhibitor of kinesin motors. | Q43745151 |
| | Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages | Q45306203 |
| | Impact of high-throughput screening in biomedical research | Q45352809 |
| | Three-dimensional structure-activity relationship study of belactosin A and its stereo- and regioisomers: development of potent proteasome inhibitors by a stereochemical diversity-oriented strategy. | Q45933219 |
| | A novel inhibitor of indole-3-glycerol phosphate synthase with activity against multidrug-resistant Mycobacterium tuberculosis | Q46229436 |
| | Flotillin and RacH modulate the intracellular immunity of Dictyostelium to Mycobacterium marinum infection | Q46473864 |
| | Eat Prey, Live: Dictyostelium discoideum As a Model for Cell-Autonomous Defenses. | Q47556585 |
| | Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity | Q47736263 |
| | Formation of the Legionella-containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics. | Q47865277 |
| | Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α. | Q49014747 |
| | When Dicty Met Myco, a (Not So) Romantic Story about One Amoeba and Its Intracellular Pathogen | Q49623828 |
| | Dictyostelium discoideum as a surrogate host-microbe model for antivirulence screening in Pseudomonas aeruginosa PAO1. | Q50219316 |
| | A Mycobacterium marinum TesA mutant defective for major cell wall-associated lipids is highly attenuated in Dictyostelium discoideum and zebrafish embryos | Q33837348 |
| | 2,3-Substituted quinoxalin-6-amine analogs as antiproliferatives: a structure-activity relationship study | Q33837666 |
| | Eat, kill or die: when amoeba meets bacteria | Q34012225 |
| | Medicinal plants in therapy | Q34193129 |
| | NetWalker: a contextual network analysis tool for functional genomics | Q34316790 |
| | Molecular characterization of the evolution of phagosomes | Q34344310 |
| | Fueling open-source drug discovery: 177 small-molecule leads against tuberculosis | Q34544301 |
| | ABC multidrug transporters: structure, function and role in chemoresistance. | Q34586418 |
| | Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. | Q34626231 |
| | Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts | Q34969920 |
| | Intracellular replication of Mycobacterium marinum within Dictyostelium discoideum: efficient replication in the absence of host coronin | Q35013023 |
| | A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy | Q35561761 |
| | Progress and challenges in implementing HIV care and treatment policies in Latin America following the treatment 2.0 initiative | Q35873661 |
| | Dictyostelium as host model for pathogenesis | Q36023742 |
| | Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila | Q36131365 |
| | High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistance | Q36410455 |
| | Environmental predators as models for bacterial pathogenesis. | Q36734988 |
| | Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation | Q36798747 |
| | A quantitative model of intracellular growth of Legionella pneumophila in Acanthamoeba castellanii. | Q36954660 |
| | Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506? | Q37622487 |
| | Amoebae as a tool to isolate new bacterial species, to discover new virulence factors and to study the host-pathogen interactions | Q37843856 |
| | Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 - 2010). | Q37886187 |
| | From amoeba to macrophages: exploring the molecular mechanisms of Legionella pneumophila infection in both hosts | Q38129263 |
| | Relevance of free-living amoebae as hosts for phylogenetically diverse microorganisms | Q38211766 |
| | Predicting natural product value, an exploration of anti-TB drug space. | Q38216493 |
| | Legionella pneumophila: homeward bound away from the phagosome | Q38280765 |
| | Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones. | Q38436575 |
| | Adrenergic antagonists restrict replication of Legionella | Q38887229 |
| | A model to predict anti-tuberculosis activity: value proposition for marine microorganisms | Q38894536 |
| | Synthesis and biological evaluation of benzo[4,5]imidazo[1,2-c]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrazine derivatives as anaplastic lymphoma kinase inhibitors | Q39030057 |
| | Dinitrophenol, Dicoumarol and Pentachlorophenol as Inhibitors and Parasite Substrates in the ATP Phosphoribosyltransferase Reaction | Q39394743 |
| | Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages | Q39610405 |
| | Antimetastatic effect of a small-molecule vacuolar H+-ATPase inhibitor in in vitro and in vivo preclinical studies | Q40073510 |
| | The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. | Q40110647 |
| | Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model | Q40126421 |
| | Acanthamoeba and Dictyostelium as Cellular Models for Legionella Infection. | Q52350987 |
| | Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets. | Q52676415 |
| | How To Optimize Shape-Based Virtual Screening: Choosing the Right Query and Including Chemical Information | Q53348684 |
| | A unified, probabilistic framework for structure- and ligand-based virtual screening. | Q53438912 |
| | Genome sequencing and functional characterization of the non-pathogenic Klebsiella pneumoniae KpGe bacteria. | Q54213669 |
| | Design, synthesis, and biological evaluation of fluorinated analogues of salicylihalamide. | Q54776757 |
| | High throughput evaluation of macrocyclization strategies for conformer stabilization. | Q55178656 |
| | Combined docking and molecular dynamics simulations to enlighten the capacity of Pseudomonas cepacia and Candida antarctica lipases to catalyze quercetin acetylation | Q56927779 |
| | Tuberculosis | Q57235679 |
| | Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis | Q57291166 |
| | In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors | Q58001173 |
| | Pancreatic lipase inhibition activity of trilactone terpenes ofGinkgo biloba | Q59447017 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ggplot2 | Q326489 |
| | RStudio | Q4798119 |
| | dplyr | Q104854189 |
| P304 | page(s) | 266 | |
| P577 | publication date | 2020-02-21 | |
| P1433 | published in | Frontiers in Microbiology | Q27723481 |
| P1476 | title | Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models | |
| P478 | volume | 11 | |