Towards re-purposing BH3-mimetics in Legionella and viral infections

scientific article published on 22 November 2017

Towards re-purposing BH3-mimetics in Legionella and viral infections is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

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P356DOI10.1080/14787210.2017.1409621
P8608Fatcat IDrelease_gwedapsatvhibefy4xfn22avji
P698PubMed publication ID29166790

P2093author name stringThomas Naderer
P2860cites workLegionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein familyQ24677004
Uncertainties associated with assessing the public health risk from LegionellaQ27026775
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic AcidQ27316130
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing plateletsQ27683708
Exploring anti-bacterial compounds against intracellular LegionellaQ28533449
Legionella pneumophila Strain 130b Evades Macrophage Cell Death Independent of the Effector SidF in the Absence of FlagellinQ30838773
Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.Q33841951
Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogensQ34026297
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Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansionQ35202685
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The Influence of Programmed Cell Death in Myeloid Cells on Host Resilience to Infection with Legionella pneumophila or Streptococcus pyogenes.Q36223568
NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.Q36228869
IL-1α signaling initiates the inflammatory response to virulent Legionella pneumophila in vivoQ36929384
The Legionella pneumophila replication vacuole: making a cosy niche inside host cellsQ37326393
Host translation at the nexus of infection and immunityQ38053751
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.Q38172752
Formation of a pathogen vacuole according to Legionella pneumophila: how to kill one bird with many stones.Q38436575
Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosisQ39477734
Anti-apoptotic signalling by the Dot/Icm secretion system of L. pneumophilaQ40243451
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.Q40559486
Probable Person-to-Person Transmission of Legionnaires' Disease.Q55059567
P433issue12
P304page(s)1071-1073
P577publication date2017-11-22
P1433published inExpert Review of Anti-infective TherapyQ15734432
P1476titleTowards re-purposing BH3-mimetics in Legionella and viral infections
P478volume15