Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

scientific article published on 09 September 2011

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ANIE.201102967
P698PubMed publication ID21905186

P50authorHerbert WaldmannQ1609256
Gemma TriolaQ30503863
Marco BürgerQ37619187
Frank J DekkerQ39476878
P2093author name stringIngrid R Vetter
Tobias J Zimmermann
Stephan A Sieber
Christian Hedberg
Andreas Brockmeyer
Petra Janning
Thomas Böttcher
Marion Rusch
Kristina Görmer
P2860cites workSmall-molecule inhibition of APT1 affects Ras localization and signalingQ24307840
Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivoQ27939571
A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS)Q28273568
An acylation cycle regulates localization and activity of palmitoylated Ras isoformsQ28306968
Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activitiesQ34089464
Ras proteins: different signals from different locationsQ35120159
Bioorthogonal organic chemistry in living cells: novel strategies for labeling biomoleculesQ35986054
Thematic review series: lipid posttranslational modifications. Lysosomal metabolism of lipid-modified proteinsQ36455039
Analytical platforms for activity-based protein profiling--exploiting the versatility of chemistry for functional proteomicsQ36492108
Mechanism-based profiling of enzyme familiesQ36559644
Protein acyl thioesterases (Review).Q37359990
Ras-MAPK pathway as a therapeutic target in cancer--emphasis on bladder cancer.Q37516197
Profiling enzyme activities in vivo using click chemistry methodsQ40560071
Depalmitoylation of endothelial nitric-oxide synthase by acyl-protein thioesterase 1 is potentiated by Ca(2+)-calmodulinQ45345675
Beta-lactones as specific inhibitors of ClpP attenuate the production of extracellular virulence factors of Staphylococcus aureusQ46321774
Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.Q46460108
The antiproliferative agent didemnin B uncompetitively inhibits palmitoyl protein thioesteraseQ47813181
Bioorganic synthesis of lipid-modified proteins for the study of signal transduction.Q53918579
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectcatalysisQ82264
general chemistryQ909510
P304page(s)9838-9842
P577publication date2011-09-09
P1433published inAngewandte Chemie International EditionQ62023953
P1476titleIdentification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M
P478volume50

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cites work (P2860)
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