The first intron of the myelin proteolipid protein gene confers cell type-specific expression by a transcriptional repression mechanism in non-expressing cell types

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The first intron of the myelin proteolipid protein gene confers cell type-specific expression by a transcriptional repression mechanism in non-expressing cell types is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0378-1119(97)00435-6
P698PubMed publication ID9409778

P2093author name stringDobretsova A
Wight PA
P2860cites workMyelin-specific proteolipid protein is expressed in myelinating Schwann cells but is not incorporated into myelin sheathsQ44136853
Mutations in the myelin proteolipid protein gene alter oligodendrocyte gene expression in jimpy and jimpymsd mice.Q52054165
Structure and expression of the mouse myelin proteolipid protein gene.Q52076828
Expression of the myelin proteolipid protein gene in the human fetal thymus.Q52200894
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Identification and characterization of a human CD4 silencerQ71047954
Dual luminescence-based reporter gene assay for luciferase and beta-galactosidaseQ71702702
Introns: evolution and functionQ30419541
Structure and expression of proteolipid protein in the peripheral nervous systemQ30989179
DM20 mRNA splice product of the myelin proteolipid protein gene is expressed in the murine heartQ31146358
Interaction of origin binding protein with an origin of replication of herpes simplex virus 1.Q33569553
A relational database of transcription factorsQ35834981
A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirementsQ35885778
A consensus sequence for cleavage by vertebrate DNA topoisomerase II.Q36010020
A myelin proteolipid protein-LacZ fusion protein is developmentally regulated and targeted to the myelin membrane in transgenic miceQ36233433
Striking similarities between the regulatory mechanisms governing yeast mating-type genes and mammalian major histocompatibility complex genesQ36729166
An S1 nuclease-sensitive region in the first intron of human platelet-derived growth factor A-chain gene contains a negatively acting cell type-specific regulatory elementQ40225927
Compilation of vertebrate-encoded transcription factorsQ40411319
An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1.Q40523037
Evolution of the intron-exon structure of eukaryotic genesQ41068207
Transcriptional silencer of the Wilms' tumor gene WT1 contains an Alu repeatQ41323263
Identification and characterization of a novel transcriptional silencer in the human collagen type IV gene COL4A2.Q41346074
Expression of Myelin Protein Genes and Other Myelin Components in an Oligodendrocytic Cell Line Conditionally Immortalized with a Temperature‐Sensitive RetrovirusQ41577658
Regulation of rodent myelin proteolipid protein gene expressionQ41634472
Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant miceQ42638631
Silencer elements modulate the expression of the gene for the neuron-glia cell adhesion molecule, Ng-CAM.Q42824506
Developmental Expression of Proteolipid Protein and DM20 mRNAs and Proteins in the Rat BrainQ43735105
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)111-117
P577publication date1997-11-01
P1433published inGeneQ5531065
P1476titleThe first intron of the myelin proteolipid protein gene confers cell type-specific expression by a transcriptional repression mechanism in non-expressing cell types
P478volume201

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cites work (P2860)
Q40951500Antisilencing: myelin proteolipid protein gene expression in oligodendrocytes is regulated via derepression
Q35126306Control of human PLP1 expression through transcriptional regulatory elements and alternatively spliced exons in intron 1
Q47808566Current concepts of PLP and its role in the nervous system
Q42993424Down-regulation of rat mitochondrial branched-chain 2-oxoacid dehydrogenase kinase gene expression by glucocorticoids
Q34939701Expression of myelin genes: comparative analysis of Oli-neu and N20.1 oligodendroglial cell lines
Q40855115Functional characterization of a cis-acting DNA antisilencer region that modulates myelin proteolipid protein gene expression
Q31402007Identification of a new exon in the myelin proteolipid protein gene encoding novel protein isoforms that are restricted to the somata of oligodendrocytes and neurons
Q28571064LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.
Q37151226Leydig cells express the myelin proteolipid protein gene and incorporate a new alternatively spliced exon
Q28202760Molecular cloning and characterization of the human budding uninhibited by benomyl (BUB3) promoter
Q48477173Myelin proteolipid protein (Plp) intron 1 DNA is required to temporally regulate Plp gene expression in the brain
Q22009103Organization of the gene for gelatin-binding protein (GBP28)
Q34192362Perspective: transposable elements, parasitic DNA, and genome evolution
Q36252501Proteomic analysis of nuclear factors binding to an intronic enhancer in the myelin proteolipid protein gene
Q28513625Repression of myelin proteolipid protein gene expression is mediated through both general and cell type-specific negative regulatory elements in nonexpressing cells
Q47859045Structural analysis and transcript processing of the bovine proteolipid protein (PLP) gene.
Q28202101Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells
Q36569224Targeted deletion of the antisilencer/enhancer (ASE) element from intron 1 of the myelin proteolipid protein gene (Plp1) in mouse reveals that the element is dispensable for Plp1 expression in brain during development and remyelination
Q48219039The oligodendrocyte-myelin glycoprotein gene is highly expressed during the late stages of myelination in the rat central nervous system.
Q52570602The wmN1 enhancer region in intron 1 is required for expression of human PLP1.
Q35513380YY1 negatively regulates mouse myelin proteolipid protein (Plp1) gene expression in oligodendroglial cells

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