Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues

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Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M906554199
P698PubMed publication ID10807926
P5875ResearchGate publication ID12509747

P50authorHarald StenmarkQ17109045
P2093author name stringGaullier JM
Gillooly DJ
Ronning E
P2860cites workSARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptorQ22008583
The Rab5 effector EEA1 interacts directly with syntaxin-6Q22010591
Syntaxin-16, a putative Golgi t-SNAREQ24316198
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motifQ24320229
EEA1 links PI(3)K function to Rab5 regulation of endosome fusionQ24322668
Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factorQ24336343
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1Q24531380
Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27pQ27618582
Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transductionQ27621560
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene productQ27860841
The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.Q27930387
Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosomeQ27931703
Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domainsQ27933286
Signalling through phosphoinositide 3-kinases: the lipids take centre stageQ28141934
Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13Q28142791
FYVE fingers bind PtdIns(3)PQ28279043
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE fingerQ28289331
Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular bodyQ29547922
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiaeQ29620184
The role of phosphoinositide 3-kinase lipid products in cell functionQ33543235
Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesisQ35198297
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimerQ38328008
Expression of Rab GTPases using recombinant vaccinia virusesQ41386387
The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localizationQ42806047
A functional PtdIns(3)P-binding motifQ47713511
Non-replicating vaccinia vector efficiently expresses bacteriophage T7 RNA polymeraseQ57081505
Phosphatidylinositol 3-Phosphate Recognition by the FYVE DomainQ57800410
High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase ActivityQ57986498
P433issue32
P407language of work or nameEnglishQ1860
P304page(s)24595-24600
P577publication date2000-08-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleInteraction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
P478volume275

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cites work (P2860)
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