| Q35222221 | A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus |
| Q96435393 | A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis |
| Q50657985 | A green GEM: intriguing analogies with animal geminin. |
| Q34547412 | ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks |
| Q47110172 | Ablation of an Ovarian Tumor Family Deubiquitinase Exposes the Underlying Regulation Governing the Plasticity of Cell Cycle Progression in Toxoplasma gondii |
| Q30440621 | An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication |
| Q35808481 | An inactive geminin mutant that binds cdt1 |
| Q34436446 | Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis |
| Q36189251 | Behavior of replication origins in Eukaryota - spatio-temporal dynamics of licensing and firing |
| Q34801657 | CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis. |
| Q34610953 | CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit |
| Q48144078 | Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development |
| Q42162912 | Cathepsin L inhibitor I blocks mitotic chromosomes decondensation during cleavage cell cycles of sea urchin embryos |
| Q35948990 | Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage |
| Q35107397 | Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells. |
| Q46252946 | Cell Cycle Synchronization in Xenopus Egg Extracts. |
| Q33312107 | Checkpoint effects and telomere amplification during DNA re-replication in fission yeast |
| Q104611664 | Comparative genomic analysis reveals evolutionary and structural attributes of MCM gene family in Arabidopsis thaliana and Oryza sativa |
| Q64250001 | Control of Eukaryotic DNA Replication Initiation-Mechanisms to Ensure Smooth Transitions |
| Q33255742 | DDB1 maintains genome integrity through regulation of Cdt1 |
| Q38213228 | DNA replication and oncogene-induced replicative stress |
| Q24312094 | DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint |
| Q40430425 | Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase |
| Q58133838 | Depletion of the pre‐RC proteins induces Chk1/Chk2 independent checkpoint responses and apoptotic cell death in HeLa cells |
| Q41965807 | Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision. |
| Q40256586 | Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability. |
| Q39129632 | Distinct action of the retinoblastoma pathway on the DNA replication machinery defines specific roles for cyclin-dependent kinase complexes in prereplication complex assembly and S-phase progression |
| Q38035836 | Dormant origins, the licensing checkpoint, and the response to replicative stresses |
| Q39340066 | Dynamic association of ORCA with prereplicative complex components regulates DNA replication initiation. |
| Q36382165 | Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos. |
| Q30995725 | Dynamic recruitment of licensing factor Cdt1 to sites of DNA damage |
| Q42161292 | ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing |
| Q35878801 | Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity |
| Q35895768 | Excess Cdt1 inhibits nascent strand elongation by repressing the progression of replication forks in Xenopus egg extracts |
| Q38103251 | Flipping the switch from g1 to s phase with e3 ubiquitin ligases |
| Q24794160 | Functional domains of the Xenopus replication licensing factor Cdt1 |
| Q28590548 | GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication |
| Q34360187 | Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice |
| Q36716372 | Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility |
| Q42668770 | Geminin deletion in pre-meiotic DNA replication stage causes spermatogenesis defect and infertility |
| Q48641925 | Geminin is required for mitotic proliferation of spermatogonia |
| Q35558059 | Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells |
| Q36173402 | Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis |
| Q47845446 | Geminin prevents rereplication during xenopus development |
| Q42630636 | Geminin restrains mesendodermal fate acquisition of embryonic stem cells and is associated with antagonism of Wnt signaling and enhanced polycomb-mediated repression |
| Q37447957 | Geminin stabilizes Cdt1 during meiosis in Xenopus oocytes |
| Q33847145 | Geminin-deficient neural stem cells exhibit normal cell division and normal neurogenesis |
| Q38913723 | Genome Duplication at the Beginning of Mammalian Development |
| Q37245727 | Genome Duplication: The Heartbeat of Developing Organisms |
| Q24544016 | Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant |
| Q34355626 | Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication |
| Q39909069 | Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase |
| Q53506242 | Human Cdt1 lacking the evolutionarily conserved region that interacts with MCM2-7 is capable of inducing re-replication. |
| Q36489137 | Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1 |
| Q39417419 | Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents. |
| Q51588092 | Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing. |
| Q48788536 | Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress |
| Q36403871 | MCM proteins and DNA replication |
| Q45621348 | MCM9 binds Cdt1 and is required for the assembly of prereplication complexes |
| Q42141837 | Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation |
| Q35237385 | Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase |
| Q46891225 | Microinjection of an antibody against the cysteine-protease involved in male chromatin remodeling blocks the development of sea urchin embryos at the initial cell cycle |
| Q37689837 | Molecular mechanisms of DNA replication checkpoint activation |
| Q50898750 | Mutant analysis of Cdt1's function in suppressing nascent strand elongation during DNA replication in Xenopus egg extracts. |
| Q53442115 | New cell or new cycle? |
| Q41311707 | Overexpression of CDT1 Is a Predictor of Poor Survival in Patients with Hepatocellular Carcinoma |
| Q81640024 | PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication |
| Q35984222 | Polo-like kinase 1 (Plk1): an Unexpected Player in DNA Replication |
| Q60633551 | Polyubiquitylation drives replisome disassembly at the termination of DNA replication |
| Q36220565 | Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins |
| Q24653685 | Preventing re-replication of chromosomal DNA. |
| Q24632601 | Prevention of DNA re-replication in eukaryotic cells |
| Q27658141 | Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing |
| Q36348378 | Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation. |
| Q51740356 | Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells. |
| Q38120365 | Regulating DNA replication in eukarya |
| Q36464843 | Regulating the licensing of DNA replication origins in metazoa |
| Q37628282 | Regulation of DNA Replication in Early Embryonic Cleavages. |
| Q36563149 | Regulation of S phase. |
| Q24537658 | Regulation of replication licensing by acetyltransferase Hbo1. |
| Q24644766 | Replication licensing and cancer--a fatal entanglement? |
| Q34473453 | Replication stress and cancer |
| Q37078588 | Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts |
| Q30438278 | Right place, right time, and only once: replication initiation in metazoans |
| Q53626522 | Role of geminin: from normal control of DNA replication to cancer formation and progression? |
| Q34073816 | SCF-FBXO31 E3 ligase targets DNA replication factor Cdt1 for proteolysis in the G2 phase of cell cycle to prevent re-replication |
| Q24648529 | Selective killing of cancer cells by suppression of geminin activity |
| Q40072036 | Site-specific interaction of the murine pre-replicative complex with origin DNA: assembly and disassembly during cell cycle transit and differentiation |
| Q34377589 | Sororin cooperates with the acetyltransferase Eco2 to ensure DNA replication-dependent sister chromatid cohesion |
| Q36012750 | Sororin is a master regulator of sister chromatid cohesion and separation |
| Q41967501 | Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation |
| Q28291913 | Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells |
| Q36149319 | The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted. |
| Q36898085 | The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing |
| Q33294960 | The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells |
| Q38613394 | The Toxoplasma Centrocone Houses Cell Cycle Regulatory Factors |
| Q24537591 | The chromosome cycle: coordinating replication and segregation. Second in the cycles review series |
| Q35694176 | The dynamics of replication licensing in live Caenorhabditis elegans embryos. |
| Q98510244 | The role of Anaphase Promoting Complex activation, inhibition and substrates in cancer development and progression |
| Q34661644 | The role of pre-replicative complex (pre-RC) components in oncogenesis |
| Q37187972 | To cell cycle, swing the APC/C. |
| Q24304921 | Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis. |