| scholarly article | Q13442814 |
| P2093 | author name string | J Julian Blow | |
| Maren Oehlmann | |||
| M Gloria Luciani | |||
| P2860 | cites work | Regulation and mechanisms of mammalian double-strand break repair | Q22121978 |
| The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis | Q24291114 | ||
| Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase cdk | Q24533333 | ||
| Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing | Q24535710 | ||
| Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint | Q24604730 | ||
| The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase | Q24682656 | ||
| Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication | Q24685710 | ||
| Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA | Q24806674 | ||
| Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition | Q27641764 | ||
| The crystal structure of cyclin A | Q27732570 | ||
| CLB5-dependent activation of late replication origins in S. cerevisiae. | Q27932788 | ||
| Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin | Q27933399 | ||
| Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair | Q27935229 | ||
| Cdc7 is required throughout the yeast S phase to activate replication origins. | Q27936667 | ||
| RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. | Q27937465 | ||
| Checkpoints: controls that ensure the order of cell cycle events | Q28131705 | ||
| The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
| An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication | Q28204037 | ||
| DNA double-strand breaks: signaling, repair and the cancer connection | Q28204231 | ||
| ATR and ATRIP: Partners in Checkpoint Signaling | Q28207471 | ||
| Caffeine inhibits the checkpoint kinase ATM | Q28374785 | ||
| Cell cycle checkpoints: preventing an identity crisis | Q29547644 | ||
| Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint | Q29614219 | ||
| The DNA replication checkpoint response stabilizes stalled replication forks | Q29618306 | ||
| A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication | Q29618307 | ||
| Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway | Q29976888 | ||
| A requirement for replication in activation of the ATR-dependent DNA damage checkpoint | Q30848079 | ||
| Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis | Q30939848 | ||
| Cell cycle regulation of Dfp1, an activator of the Hsk1 protein kinase | Q33868514 | ||
| Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system. | Q33929318 | ||
| Control of chromosomal DNA replication in the early Xenopus embryo | Q34080275 | ||
| Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs | Q34190376 | ||
| Control of DNA replication licensing in a cell cycle | Q34523944 | ||
| Replication licensing--defining the proliferative state? | Q34534992 | ||
| Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin | Q34663629 | ||
| Replication timing and transcriptional control: beyond cause and effect | Q34688494 | ||
| Checking on the fork: the DNA-replication stress-response pathway | Q35006441 | ||
| Paradoxes of eukaryotic DNA replication: MCM proteins and the random completion problem. | Q35050088 | ||
| A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication | Q35204315 | ||
| Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts | Q35206290 | ||
| Many fingers on the mitotic trigger: post-translational regulation of the Cdc25C phosphatase. | Q35601099 | ||
| Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II. | Q36124945 | ||
| The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts | Q36276718 | ||
| DNA damage-induced replication arrest in Xenopus egg extracts | Q36324538 | ||
| Replication origins in Xenopus egg extract Are 5-15 kilobases apart and are activated in clusters that fire at different times | Q36370052 | ||
| Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control | Q36490482 | ||
| Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity. | Q39456364 | ||
| DNA replication initiates at multiple sites on plasmid DNA in Xenopus egg extracts. | Q40421421 | ||
| The Cdc7 protein kinase is required for origin firing during S phase | Q40442830 | ||
| Xenopus cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading | Q40443609 | ||
| Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest | Q40692379 | ||
| Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. | Q40816316 | ||
| Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints | Q41063544 | ||
| Cell cycle regulation of the replication licensing system: involvement of a Cdk-dependent inhibitor | Q41836897 | ||
| Eucaryotic DNA: organization of the genome for replication | Q41891888 | ||
| Aphidicolin triggers a block to replication origin firing in Xenopus egg extracts | Q43560219 | ||
| Xenopus Drf1, a regulator of Cdc7, displays checkpoint-dependent accumulation on chromatin during an S-phase arrest | Q44277681 | ||
| A central role for DNA replication forks in checkpoint activation and response | Q44455872 | ||
| Activation of the DNA replication checkpoint through RNA synthesis by primase | Q46682507 | ||
| Replication fork density increases during DNA synthesis in X. laevis egg extracts | Q48886447 | ||
| Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. | Q48965240 | ||
| Characterization of the Xenopus replication licensing system. | Q48966851 | ||
| Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage | Q50722584 | ||
| Evidence for sequential action of cdc7 and cdk2 protein kinases during initiation of DNA replication in Xenopus egg extracts | Q50723158 | ||
| Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. | Q52536369 | ||
| Ensuring the stability of the genome: DNA damage checkpoints | Q53378764 | ||
| Replication control: Choreographing replication origins | Q60482307 | ||
| Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts | Q71517255 | ||
| Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases | Q72531722 | ||
| Mechanisms ensuring rapid and complete DNA replication despite random initiation in Xenopus early embryos | Q73454606 | ||
| Regulation of DNA-replication origins during cell-cycle progression | Q77448213 | ||
| P433 | issue | Pt 25 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6019-6030 | |
| P577 | publication date | 2004-11-09 | |
| P1433 | published in | Journal of Cell Science | Q1524177 |
| P1476 | title | Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus | |
| P478 | volume | 117 |
| Q35728207 | 5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint |
| Q28289710 | A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta |
| Q37558633 | A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers |
| Q28271944 | A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancers |
| Q38955450 | A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function |
| Q34547412 | ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks |
| Q33522555 | ATR activation and replication fork restart are defective in FANCM-deficient cells |
| Q52730124 | ATR kinase regulates its attenuation via PPM1D phosphatase recruitment to chromatin during recovery from DNA replication stress signalling |
| Q47622968 | ATR/CHK1 inhibitors and cancer therapy |
| Q37132609 | Analyzing the ATR-mediated checkpoint using Xenopus egg extracts |
| Q98775882 | C17orf53 is identified as a novel gene involved in inter-strand crosslink repair |
| Q38805276 | Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities |
| Q43073374 | Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus |
| Q40949803 | Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus |
| Q46252946 | Cell Cycle Synchronization in Xenopus Egg Extracts. |
| Q40285417 | Checkpoint kinase 1-mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine-induced G2/M phase cell-cycle arrest and apoptosis |
| Q53589100 | Chromatin loading of Smc5/6 is induced by DNA replication but not by DNA double-strand breaks |
| Q42227954 | Claspin and Chk1 regulate replication fork stability by different mechanisms |
| Q41813815 | Clusters, factories and domains: The complex structure of S-phase comes into focus. |
| Q33799163 | Continued primer synthesis at stalled replication forks contributes to checkpoint activation. |
| Q37226102 | Control of DNA replication by the nucleus/cytoplasm ratio in Xenopus |
| Q37122063 | DNA topoisomerase IIα controls replication origin cluster licensing and firing time in Xenopus egg extracts |
| Q42585685 | Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts |
| Q41965807 | Deregulated replication licensing causes DNA fragmentation consistent with head-to-tail fork collision. |
| Q37327314 | Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival |
| Q40035632 | Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. |
| Q35878801 | Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity |
| Q39729829 | Excess Mcm2-7 license dormant origins of replication that can be used under conditions of replicative stress. |
| Q34301932 | Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks |
| Q28590548 | GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication |
| Q33344279 | H2AX foci in late S/G2- and M-phase cells after hydroxyurea- and aphidicolin-induced DNA replication stress in Vicia. |
| Q42488766 | Inactivation of a macronuclear intra-S-phase checkpoint in Tetrahymena thermophila with caffeine affects the integrity of the micronuclear genome |
| Q47578230 | Inheritance of Histones H3 and H4 during DNA Replication In Vitro |
| Q38923378 | Interaction of Chk1 with Treslin negatively regulates the initiation of chromosomal DNA replication. |
| Q37983095 | Mechanisms of replication fork protection: a safeguard for genome stability |
| Q92229730 | Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements |
| Q34324063 | Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes |
| Q57755546 | NCOA4 transcriptional coactivator inhibits activation of DNA replication origins |
| Q64251963 | On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway |
| Q36096056 | Open Sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus |
| Q64268034 | RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR |
| Q33721233 | Rad17 plays a central role in establishment of the interaction between TopBP1 and the Rad9-Hus1-Rad1 complex at stalled replication forks |
| Q42929219 | Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels. |
| Q36778772 | Replication origin plasticity, Taylor-made: inhibition vs recruitment of origins under conditions of replication stress |
| Q44294870 | Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases |
| Q37078588 | Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts |
| Q42136223 | Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1. |
| Q35911163 | Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts |
| Q36906799 | SUMO2/3 modification of cyclin E contributes to the control of replication origin firing |
| Q37956284 | Surviving chromosome replication: the many roles of the S-phase checkpoint pathway |
| Q52811875 | Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in BRCA-Mutant Ovarian Cancer Models |
| Q39598250 | Temporal profiling of the chromatin proteome reveals system-wide responses to replication inhibition |
| Q33704991 | The DNA unwinding element binding protein DUE-B interacts with Cdc45 in preinitiation complex formation |
| Q30986500 | The Effect of a DNA Damaging Agent on Embryonic Cell Cycles of the Cnidarian Hydractinia echinata |
| Q37676255 | The Intra-S Checkpoint Responses to DNA Damage |
| Q30430707 | The effect of the intra-S-phase checkpoint on origins of replication in human cells |
| Q34590385 | The functional role of Cdc6 in S-G2/M in mammalian cells |
| Q39069982 | The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing |
| Q111442196 | The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation |
| Q38404075 | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome |
| Q35653663 | Tight Chk1 Levels Control Replication Cluster Activation in Xenopus |
| Q35989104 | Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts |
| Q37234359 | TopBP1 and DNA polymerase-alpha directly recruit the 9-1-1 complex to stalled DNA replication forks. |
| Q41809632 | Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1. |
| Q39666879 | Xenopus Mcm10 is a CDK-substrate required for replication fork stability. |
| Q42834998 | Y RNA functions at the initiation step of mammalian chromosomal DNA replication |
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