Butyrate and the colonocyte. Implications for neoplasia

scientific article published on April 1996

Butyrate and the colonocyte. Implications for neoplasia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF02213129
P698PubMed publication ID8674394

P2093author name stringO C Velázquez
J L Rombeau
H M Lederer
P2860cites workAcetylation and calcium-dependent phosphorylation of histone H3 in nuclei from butyrate-treated HeLa cellsQ71653902
In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-Fos and c-Jun expressionQ71671010
Stimulatory effect of short chain fatty acids on the epithelial cell proliferation in rat large intestineQ72548133
Mediation of the trophic effects of short-chain fatty acids on the rat jejunum and colonQ72754015
Manifold effects of sodium butyrate on nuclear function. Selective and reversible inhibition of phosphorylation of histones H1 and H2A and impaired methylation of lysine and arginine residues in nuclear protein fractionsQ72909015
Butyrate rapidly induces growth inhibition and differentiation in HT-29 cellsQ72927357
Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1Q24339633
Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215).Q24548152
Altered levels of laminin receptor mRNA in various human carcinoma cells that have different abilities to bind lamininQ24629632
Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structuresQ24679747
A genetic model for colorectal tumorigenesisQ27860582
Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiationQ28213713
Genetic alterations during colorectal-tumor developmentQ28281200
Molecular analysis of sodium butyrate-induced growth arrest.Q34167846
Dietary intake of fiber and decreased risk of cancers of the colon and rectum: evidence from the combined analysis of 13 case-control studiesQ34239297
Effects of sodium butyrate, a new pharmacological agent, on cells in cultureQ34249353
Alkaline phosphatase in HT-29, a human colon cancer cell line: Influence of sodium butyrate and hyperosmolalityQ34284196
Butyrate production from dietary fibre and protection against large bowel cancer in a rat modelQ34376463
Short chain fatty acids in human large intestine, portal, hepatic and venous bloodQ34529426
myc function and regulationQ35671084
Detection of the c-myc oncogene product in colonic polyps and carcinomasQ36027335
Hypomethylation of DNA during differentiation of Friend erythroleukemia cellsQ36203641
Distribution of a 69-kD laminin-binding protein in aortic and microvascular endothelial cells: modulation during cell attachment, spreading, and migrationQ36218583
Modulation of the cluster 1 and mucin antigens in human small cell lung cancer and other epithelial tumour cell lines after treatment with the differentiation inducing agent, sodium butyrateQ36389588
Butyrate suppression of histone deacetylation leads to accumulation of multiacetylated forms of histones H3 and H4 and increased DNase I sensitivity of the associated DNA sequencesQ37585853
Laminin receptor on human breast carcinoma cellsQ37601668
Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2.Q38318999
Biology of large bowel cancerQ38603288
Relationship between dietary fiber and cancer: metabolic, physiologic, and cellular mechanismsQ39506319
Role of dietary factors in cell replication and colon cancerQ39520381
Biomarkers of increased susceptibility to gastrointestinal cancer: new application to studies of cancer prevention in human subjects.Q39625435
Expression of poly(adenosine diphosphate-ribose) polymerase activity in erythroleukemic mouse cells during cell cycle and erythropoietic differentiationQ40152366
Influence of short chain fatty acids on the epithelial cell division of digestive tractQ40185579
Sodium butyrate induces new gene expression in Friend erythroleukemic cellsQ40591798
The role of carbohydrate fermentation in colon cancer prevention.Q40664116
Metabolism of the malignant cell, in vivo, is anaerobic and significantly plays a factor in the pathway to carcinogenesisQ41107591
Effect of short-chain fatty acids on the human colonic mucosa in vitroQ41142770
Malignancy may contribute to rapid evolutionQ41351770
Histochemical demonstration of alkaline phosphatase in human large intestine, normal and diseasedQ41497898
Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancerQ41526050
Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells.Q41526488
Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2.Q41542179
Differential effects of laminin, intact type IV collagen, and specific domains of type IV collagen on endothelial cell adhesion and migrationQ41546361
mdr 1 gene-expression and villin synthesis in a colon cancer cell line differentiated by sodium butyrateQ41566666
Colonic cancer cell (HT29) adhesion to laminin is altered by differentiation: adhesion may involve galactosyltransferaseQ41609694
Contrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitroQ41636593
Cell surface sialoprotein alterations in metastatic murine colon cancer cell lines selected in an animal model for colon cancer metastasisQ41743861
Effects of fatty acids on expression of genes encoding subunits of cytochrome c oxidase and cytochrome c oxidase activity in HT29 human colonic adenocarcinoma cells.Q41788567
Influence of butyrate on lipid metabolism, survival, and differentiation of colon cancer cellsQ41978788
Laminin alters cell shape and stimulates motility and proliferation of murine skeletal myoblastsQ42517748
Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cellsQ42795931
Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans.Q43647345
Cornstarch fermentation by the colonic microbial community yields more butyrate than does cabbage fiber fermentation; cornstarch fermentation rates correlate negatively with methanogenesisQ43955557
Modification of Ha-ras oncogene p21 expression and cell cycle progression in the human colonic cancer cell line HT-29.Q44365588
Stimulation of absorption of volatile fatty acids and minerals in the cecum of rats adapted to a very high fiber dietQ44400649
Determination of the levels of urokinase and its receptor in human colon carcinoma cell linesQ44582678
Comparison of fermentation reactions in different regions of the human colonQ44631063
Stimulatory effect of short-chain fatty acids on epithelial cell proliferation of isolated and denervated jejunal segment of the rat.Q44836712
Colonic mucosal atrophy induced by a liquid elemental diet in ratsQ45795415
Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents.Q45825109
Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell linesQ46115928
Transcriptional regulation of the human placental-like alkaline phosphatase gene and mechanisms involved in its induction by sodium butyrateQ46242843
Fermentation of polysaccharides and absorption of short chain fatty acids in the mammalian hindgutQ46887173
Effects of deoxycholic acid and butyrate on mucosal prostaglandin E2 release and cell proliferation in the human sigmoid colonQ53463834
Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH.Q53479310
The p21 ras C-terminus is required for transformation and membrane associationQ53551139
Effect of growth and sodium butyrate on brush border membrane-associated hydrolases in human colorectal cancer cell linesQ53759908
Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell linesQ54231075
Sensitivity of nuclear c-myc levels and induction to differentiation-inducing agents in human colon tumor cell linesQ54275436
Fermentation of dietary fibre components in the rat intestinal tractQ54518422
Nuclear oncogene amplification or rearrangement is not involved in human colorectal malignanciesQ57056556
Dietary fat and fiber modulate colonic cell proliferation in an interactive site‐specific mannerQ58450306
Prevalence of ras gene mutations in human colorectal cancersQ59088716
Suppression of histone deacetylation in vivo and in vitro by sodium butyrateQ67327928
Different accessibilities in chromatin to histone acetylaseQ67469159
Parenteral nutrition supplemented with short-chain fatty acids: effect on the small-bowel mucosa in normal ratsQ67656292
Effect of Short-Chain Fatty Acids on Colonic Function and StructureQ67750196
Fermentability of various fiber sources by human fecal bacteria in vitroQ67916549
Brush border hydrolases in normal and neoplastic colonic epitheliumQ68031865
Increased cell surface EGF receptor expression during the butyrate-induced differentiation of human HCT-116 colon tumor cell clonesQ68093798
Oncogene expression in adenocarcinomas of the colon and in colon tumor-derived cell linesQ68133276
DNA hypermethylation in sodium butyrate-treated WI-38 fibroblastsQ68955298
Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cellsQ69100955
Stimulation of intestinal mucosal growth with intracolonic infusion of short-chain fatty acidsQ69191254
Expression of the c-myc gene in human gastrointestinal malignanciesQ69198318
Stimulatory effect of short-chain fatty acids on epithelial cell proliferation in the rat intestine: a possible explanation for trophic effects of fermentable fibre, gut microbes and luminal trophic factorsQ69200886
Tritiated-thymidine labeling of rectal epithelial cells in 'non-prep' biopsies of individuals at increased risk for colonic neoplasiaQ69442598
Expression of the myc gene family in different stages of human colorectal cancerQ69527858
Localization of plasminogen activators in human colon cancer by immunoperoxidase stainingQ69885785
Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell linesQ69936062
Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary noteQ69938754
Butyrate induced reduction of tumor cell laminin receptorsQ69981949
Differential effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on membrane-associated antigen, enzymes, and glycoproteins of human rectal adenocarcinoma cellsQ70282524
The cellular interactions of laminin fragments. Cell adhesion correlates with two fragment-specific high affinity binding sitesQ70355578
Utilization of nutrients by isolated epithelial cells of the rat colonQ70370636
Oat bran but not a beta-glucan-enriched oat fraction enhances butyrate production in the large intestine of pigsQ70463145
Relationship of colonic luminal short-chain fatty acids and pH to in vivo cell proliferation in ratsQ70472322
Effect of sodium butyrate on alkaline phosphatase in HRT-18, a human rectal cancer cell lineQ70474819
Induction of protein phosphorylation, protein synthesis, immediate-early-gene expression and cellular proliferation by intracellular pH modulation. Implications for the role of hydrogen ions in signal transductionQ70669713
Fermentation in the Rumen and Human Large IntestineQ70924745
Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cellsQ71140148
Induction of placental alkaline phosphatase biosynthesis by sodium butyrateQ71275772
Butyrate is a potent inhibitor of urokinase secretion by normal colonic epithelium in vitroQ71635394
P433issue4
P304page(s)727-739
P577publication date1996-04-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inDigestive Diseases and SciencesQ15716711
P1476titleButyrate and the colonocyte. Implications for neoplasia
P478volume41

Reverse relations

cites work (P2860)
Q45135713A novel high-amylose barley cultivar (Hordeum vulgare var. Himalaya 292) lowers plasma cholesterol and alters indices of large-bowel fermentation in pigs
Q46438949A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans.
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Q41828839Butyrate induced Caco-2 cell apoptosis is mediated via the mitochondrial pathway
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Q40905894Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells
Q43980803Butyrate strongly inhibits in vitro stimulated release of cytokines in blood.
Q40778493Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity
Q36898037Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1
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