Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis

scientific article published on 3 September 2017

Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.7150/IJBS.21206
P932PMC publication ID5599913
P698PubMed publication ID28924389

P2093author name stringYing Zhang
Fei Yi
Liu Cao
Xiaoman Li
Zhijun Wang
Zhuo Wang
Jingwei Liu
Xiaoyu Song
Ning Bai
Hongde Xu
P2860cites workThe ATM-SMC1 pathway is essential for activation of the chromium[VI]-induced S-phase checkpointQ64388881
Analysis of the mammalian recombination protein complex RC-1Q71133329
Interaction between Rae1 and cohesin subunit SMC1 is required for proper spindle formationQ82267967
Re: whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregationQ86904390
Knocking down SMC1A inhibits growth and leads to G2/M arrest in human glioma cellsQ28611427
The origin and evolution of mutations in acute myeloid leukemiaQ29614630
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemiaQ29615735
Cohesin: its roles and mechanismsQ29616226
Specific recruitment of human cohesin to laser-induced DNA damageQ30847802
Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatinQ30882231
Changes in incidence and survival of Ewing sarcoma patients over the past 3 decades: Surveillance Epidemiology and End Results data.Q31157886
Review: SMCs in the world of chromosome biology- from prokaryotes to higher eukaryotesQ33915691
Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.Q34057826
Increased invasiveness and aggressiveness in breast epithelia with cytoplasmic p63 expressionQ34061980
Shaping the metaphase chromosome: coordination of cohesion and condensationQ34095025
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.Q34414087
Sisters unbound is required for meiotic centromeric cohesion in Drosophila melanogasterQ34471725
Cohesin complexes with a potential to link mammalian meiosis to cancerQ34503710
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasmsQ34655449
Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosisQ35006432
Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISAQ35069624
Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions.Q35079862
Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancerQ35155536
Time-course analysis of DNA damage response-related genes after in vitro radiation in H460 and H1229 lung cancer cell linesQ35171865
Protein deep sequencing applied to biobank samples from patients with pancreatic cancerQ35250650
Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulatorsQ35601883
Cohesin Smc1beta determines meiotic chromatin axis loop organizationQ36404923
The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tetheringQ36452407
SMC1-mediated intra-S-phase arrest facilitates bocavirus DNA replicationQ36759739
Cohesin subunit SMC1 associates with mitotic microtubules at the spindle poleQ36917033
PTIP regulates 53BP1 and SMC1 at the DNA damage sitesQ37258492
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.Q37341453
Cohesin SMC1beta protects telomeres in meiocytesQ37402354
A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair fociQ37525823
Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6.Q38319717
SMC1 involvement in fragile site expression.Q38332240
Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal human fibroblastsQ38354013
SMC1 promotes epithelial-mesenchymal transition in triple-negative breast cancer through upregulating BrachyuryQ38802114
Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamicsQ22004016
Hallmarks of Cancer: The Next GenerationQ22252312
Characterization of vertebrate cohesin complexes and their regulation in prophaseQ24290512
A potential role for human cohesin in mitotic spindle aster assemblyQ24291762
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpointQ24292395
Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaksQ24295050
Molecular architecture of SMC proteins and the yeast cohesin complexQ24296209
MDC1 is a mediator of the mammalian DNA damage checkpointQ24296229
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylationQ24301197
Localization of human SMC1 protein at kinetochoresQ24305359
The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cellsQ24317260
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding foldQ24556499
MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancerQ24629078
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancersQ24656162
A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiaeQ24657816
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damageQ24672492
The genomic landscape of pediatric Ewing sarcomaQ27853063
SMC1 coordinates DNA double-strand break repair pathwaysQ27931613
ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure.Q27932431
SMC1: an essential yeast gene encoding a putative head-rod-tail protein is required for nuclear division and defines a new ubiquitous protein familyQ27932753
Cohesins: chromosomal proteins that prevent premature separation of sister chromatidsQ27934146
Structural maintenance of chromosomes protein C-terminal domains bind preferentially to DNA with secondary structureQ27937303
Condensin and cohesin display different arm conformations with characteristic hinge anglesQ28216842
Condensins, chromosome condensation protein complexes containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren proteinQ28238784
Dynamic molecular linkers of the genome: the first decade of SMC proteinsQ28254733
Identification of Xenopus SMC protein complexes required for sister chromatid cohesionQ28275242
Role of SMC1 in overcoming drug resistance in triple negative breast cancerQ28533198
The cohesion protein SOLO associates with SMC1 and is required for synapsis, recombination, homolog bias and cohesion and pairing of centromeres in Drosophila MeiosisQ28534710
Downregulation of SMC1A inhibits growth and increases apoptosis and chemosensitivity of colorectal cancer cellsQ38814296
siRNA-mediated knockdown of SMC1A expression suppresses the proliferation of glioblastoma cellsQ39141299
Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesisQ39677519
Conserved disruptions in the predicted coiled-coil domains of eukaryotic SMC complexes: implications for structure and function.Q39860948
Cohesin protein SMC1 is a centrosomal proteinQ39976703
SMC1B is present in mammalian somatic cells and interacts with mitotic cohesin proteins.Q40206464
ATR regulates hexavalent chromium-induced S-phase checkpoint through phosphorylation of SMC1.Q40250053
A Reversible Association between Smc Coiled Coils Is Regulated by Lysine Acetylation and Is Required for Cohesin Association with the DNA.Q40585702
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathwayQ40916856
SMC proteins constitute two subunits of the mammalian recombination complex RC-1.Q41076499
Prophase pathway-dependent removal of cohesin from human chromosomes requires opening of the Smc3-Scc1 gateQ41489197
Imbalance of SMC1 and SMC3 cohesins causes specific and distinct effectsQ42028196
Characterization of a DNA exit gate in the human cohesin ring.Q42694247
Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cellsQ42726606
Cohesin is needed for bipolar mitosis in human cells.Q44240896
Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implicationsQ45041099
Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombinationQ45875368
Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1.Q47981697
Chromosome dynamics: the SMC protein familyQ48018554
SMC1beta-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction.Q50656030
Impairing Cohesin Smc1/3 Head Engagement Compensates for the Lack of Eco1 Function.Q51113178
Mutant cohesin drives chromosomal instability in early colorectal adenomas.Q53030454
The landscape of somatic mutations in Down syndrome-related myeloid disorders.Q53089292
Point mutation at the Nbs1 Threonine 278 site does not affect mouse development, but compromises the Chk2 and Smc1 phosphorylation after DNA damage.Q53241406
Low SMC1A protein expression predicts poor survival in acute myeloid leukemia.Q53321036
NBS1 prevents chromatid-type aberrations through ATM-dependent interactions with SMC1.Q53456827
Reoxygenation following hypoxia activates DNA-damage checkpoint signaling pathways that suppress cell-cycle progression in cultured human lymphocytes.Q53549095
The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.Q53677010
Cohesion between sister chromatids must be established during DNA replicationQ57270146
A mutant of Saccharomyces cerevisiae with impaired maintenance of centromeric plasmidsQ62270992
P275copyright licenseCreative Commons Attribution-NonCommercialQ6936496
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectnuclear proteinQ16860021
genetic variationQ349856
nucleoproteinQ419245
carcinogenesisQ1637543
cell cycle proteinsQ76598519
genome stabilityQ98655700
P304page(s)1092-1099
P577publication date2017-09-03
P1433published inInternational Journal of Biological SciencesQ6051326
P1476titleStructural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis
P478volume13

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cites work (P2860)
Q91027561Association mapping of magnesium and manganese concentrations in the seeds of C. arietinum and C. reticulatum
Q92733633Fresh and ozonized black carbon promoted DNA damage and repair responses in A549 cells
Q55513225Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration.
Q90119575SMC1 promotes proliferation and inhibits apoptosis through the NF‑κB signaling pathway in colorectal cancer

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