scholarly article | Q13442814 |
P2093 | author name string | Peter J McKinnon | |
Christopher J Bakkenist | |||
Michael B Kastan | |||
Risa Kitagawa | |||
P2860 | cites work | Fragments of ATM which have dominant-negative or complementing activity | Q36567594 |
BRCA1 is a cell cycle-regulated nuclear phosphoprotein | Q36648552 | ||
A mammalian protein complex that repairs double-strand breaks and deletions by recombination. | Q38317518 | ||
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism | Q39896119 | ||
Monoclonal antibodies generated against recombinant ATM support kinase activity | Q40853073 | ||
Independence of R/M/N focus formation and the presence of intact BRCA1. | Q40864224 | ||
SMC proteins constitute two subunits of the mammalian recombination complex RC-1. | Q41076499 | ||
The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia | Q41609540 | ||
Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation | Q44817175 | ||
Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage | Q47759653 | ||
Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1. | Q47981697 | ||
DNA replication-dependent nuclear dynamics of the Mre11 complex. | Q53942975 | ||
The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia | Q62746091 | ||
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage | Q72910633 | ||
Influence of ATM function on telomere metabolism | Q73945587 | ||
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest | Q74355482 | ||
In vivo site-directed mutagenesis of yeast plasmids using a three-fragment homologous recombination system | Q74630929 | ||
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway | Q22253899 | ||
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint | Q24292395 | ||
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
BRCA1 supports XIST RNA concentration on the inactive X chromosome | Q24316340 | ||
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro | Q24656275 | ||
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage | Q24672492 | ||
Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. | Q27933169 | ||
Cohesins: chromosomal proteins that prevent premature separation of sister chromatids | Q27934146 | ||
The DNA damage response: putting checkpoints in perspective | Q28131713 | ||
Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX | Q28139663 | ||
ATM: genome stability, neuronal development, and cancer cross paths | Q28201456 | ||
The many substrates and functions of ATM | Q28205055 | ||
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways | Q28207549 | ||
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage | Q28236024 | ||
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice | Q28509807 | ||
Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks | Q28609912 | ||
Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation | Q33558779 | ||
DNA damage-dependent nuclear dynamics of the Mre11 complex | Q33975168 | ||
The Mre11 complex is required for ATM activation and the G2/M checkpoint | Q34052273 | ||
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation | Q34300338 | ||
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex | Q34311086 | ||
DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
Requirement of the MRN complex for ATM activation by DNA damage | Q36267304 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 1423-1438 | |
P577 | publication date | 2004-06-02 | |
P1433 | published in | Genes & Development | Q1524533 |
P1476 | title | Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway | |
P478 | volume | 18 |
Q39352316 | 53BP1 promotes ATM activity through direct interactions with the MRN complex |
Q28817178 | A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming |
Q34728646 | A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex |
Q35092564 | A positive role for c-Abl in Atm and Atr activation in DNA damage response. |
Q53555573 | A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. |
Q28270543 | A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM |
Q37525823 | A small ubiquitin binding domain inhibits ubiquitin-dependent protein recruitment to DNA repair foci |
Q48719100 | A spontaneous smc1b mutation causes cohesin protein dysfunction and sterility in mice |
Q39381847 | A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest |
Q40114943 | ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke |
Q33863002 | ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. |
Q34166198 | ATM and ataxia telangiectasia |
Q34722732 | ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks |
Q58804970 | ATM in breast and brain tumors: a comprehensive review |
Q33667539 | ATM is down-regulated by N-Myc-regulated microRNA-421. |
Q34298505 | ATM promotes apoptosis and suppresses tumorigenesis in response to Myc. |
Q37870855 | ATM protein kinase: the linchpin of cellular defenses to stress |
Q35213158 | ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control |
Q38846492 | ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. |
Q36023707 | ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability |
Q41971846 | ATR signaling at a glance |
Q29547883 | ATR: an essential regulator of genome integrity |
Q34722727 | Activation and regulation of ATM kinase activity in response to DNA double-strand breaks |
Q34519762 | Active role for nibrin in the kinetics of atm activation |
Q36684796 | An autonomous chromatin/DNA-PK mechanism for localized DNA damage signaling in mammalian cells |
Q33948911 | Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry |
Q37033635 | Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability |
Q33884511 | Aspergillus nidulans uvsBATR and scaANBS1 genes show genetic interactions during recovery from replication stress and DNA damage |
Q40146768 | Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents |
Q47649609 | Ataxia telangiectasia syndrome: moonlighting ATM. |
Q36617706 | Ataxia-telangiectasia and related diseases |
Q40362631 | Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo |
Q37278036 | Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer |
Q30498797 | Autophosphorylation and ATM activation: additional sites add to the complexity |
Q33589782 | Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites |
Q59098643 | Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo |
Q37605239 | Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. |
Q33731257 | BRCA1 establishes DNA damage signaling and pericentric heterochromatin of the X chromosome in male meiosis |
Q35069624 | Blood-based detection of radiation exposure in humans based on novel phospho-Smc1 ELISA |
Q39636146 | Bocavirus Infection Induces a DNA Damage Response That Facilitates Viral DNA Replication and Mediates Cell Death |
Q54981629 | Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma. |
Q83423039 | Can corruption of chromosome cohesion create a conduit to cancer? |
Q36627909 | Candidate protein biodosimeters of human exposure to ionizing radiation. |
Q81358838 | Cell biology: holding sisters for repair |
Q36882812 | Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1. |
Q28293996 | Cell-cycle checkpoints and cancer |
Q37648742 | Cellular radiosensitivity: how much better do we understand it? |
Q35906070 | Checking on DNA damage in S phase |
Q28511458 | Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage |
Q36071839 | Chloroquine improves survival and hematopoietic recovery after lethal low-dose-rate radiation |
Q26782637 | Chromatin perturbations during the DNA damage response in higher eukaryotes |
Q36660520 | Chromatin remodeling and repair of DNA double-strand breaks |
Q53157575 | Chromosomal instability induced by mammography X-rays in primary human fibroblasts from BRCA1 and BRCA2 mutation carriers. |
Q37565121 | Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms |
Q36550391 | Cohesin and DNA damage repair |
Q42726606 | Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells |
Q30882231 | Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin |
Q34140001 | Cohesin protects genes against γH2AX Induced by DNA double-strand breaks |
Q42145939 | Cohesin protein SMC1 represses the nuclear receptor CAR-mediated synergistic activation of a human P450 gene by xenobiotics |
Q36917033 | Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole |
Q42547364 | Cohesin's dual role in the DNA damage response: repair and checkpoint activation |
Q37919509 | Cohesin: a critical chromatin organizer in mammalian gene regulation |
Q37749881 | Cohesin: a regulator of genome integrity and gene expression |
Q37416042 | Cohesins: chromatin architects in chromosome segregation, control of gene expression and much more |
Q30487741 | Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells |
Q30408244 | Comprehensive profiling of radiosensitive human cell lines with DNA damage response assays identifies the neutral comet assay as a potential surrogate for clonogenic survival |
Q29614218 | Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage |
Q37292831 | Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA |
Q33290461 | Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents |
Q36349712 | DNA Damage Response Proteins and Oxygen Modulate Prostaglandin E2 Growth Factor Release in Response to Low and High LET Ionizing Radiation. |
Q36488090 | DNA damage checkpoint, damage repair, and genome stability |
Q36325437 | DNA damage checkpoints in mammals |
Q37724792 | DNA damage response is hijacked by human papillomaviruses to complete their life cycle |
Q55188923 | DNA damage response pathways in cancer causation and treatment. |
Q36402069 | DNA damage responses and their many interactions with the replication fork |
Q38134064 | DNA damage sensing by the ATM and ATR kinases. |
Q26822413 | DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosis |
Q36316482 | DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity |
Q40457853 | DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. |
Q37027200 | DNA double-strand break repair and development |
Q37368873 | DNA repair deficiency and neurological disease |
Q34183328 | DNA repair deficiency in neurodegeneration. |
Q40350268 | DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM. |
Q37154126 | DNA strand breaks, neurodegeneration and aging in the brain |
Q42007528 | DNA-PKcs and ATM co-regulate DNA double-strand break repair |
Q37032389 | Damage-induced reactivation of cohesin in postreplicative DNA repair |
Q39476754 | Defective DNA double-strand break repair in pediatric systemic lupus erythematosus |
Q52720061 | Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes. |
Q37111110 | Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS |
Q42431176 | Differential Dynamics of ATR-Mediated Checkpoint Regulators. |
Q35275785 | Dimer monomer transition and dimer re-formation play important role for ATM cellular function during DNA repair |
Q36229366 | Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis |
Q37546841 | Distinct functions of human cohesin-SA1 and cohesin-SA2 in double-strand break repair |
Q36453329 | Dual role of Nbs1 in the ataxia telangiectasia mutated-dependent DNA damage response. |
Q33602897 | Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks |
Q24649590 | Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes |
Q37956184 | Eukaryotic DNA damage checkpoint activation in response to double-strand breaks |
Q39672854 | FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses. |
Q37672541 | FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance |
Q26864654 | FOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistance |
Q37341109 | Family cancer syndromes: inherited deficiencies in systems for the maintenance of genomic integrity |
Q33859206 | Functional deficiency of NBN, the Nijmegen breakage syndrome protein, in a p.R215W mutant breast cancer cell line |
Q24298691 | Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit |
Q36735336 | Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodeling |
Q37196316 | Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients |
Q47148140 | Genome integrity and disease prevention in the nervous system |
Q34003794 | Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells |
Q33818028 | Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1. |
Q94686254 | Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response |
Q34034221 | Glioblastoma cells containing mutations in the cohesin component STAG2 are sensitive to PARP inhibition |
Q24814467 | Global gene expression profiling of cells overexpressing SMC3. |
Q54525472 | Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1). |
Q37291739 | Histone deacetylase regulation of ATM-mediated DNA damage signaling |
Q30413950 | Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks |
Q24305756 | Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation |
Q50026021 | Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification. |
Q37189141 | Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder |
Q35601883 | Human papillomaviruses activate and recruit SMC1 cohesin proteins for the differentiation-dependent life cycle through association with CTCF insulators |
Q28476215 | Human papillomaviruses activate the ATM DNA damage pathway for viral genome amplification upon differentiation |
Q37439146 | Impaired DNA damage response--an Achilles' heel sensitizing cancer to chemotherapy and radiotherapy |
Q42109796 | Induction and utilization of an ATM signaling pathway by polyomavirus |
Q33431359 | Induction of DNA damage response by the supravital probes of nucleic acids |
Q37068656 | Induction of genetic instability by gain-of-function p53 cancer mutants |
Q38270775 | Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance. |
Q39532051 | Killing of chronic lymphocytic leukemia by the combination of fludarabine and oxaliplatin is dependent on the activity of XPF endonuclease |
Q33331904 | Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase |
Q35907435 | Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium |
Q38310324 | Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction |
Q26861558 | Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies |
Q91864633 | Mechanistic link between DNA damage sensing, repairing and signaling factors and immune signaling |
Q24630465 | Mitochondrial dysfunction in ataxia-telangiectasia |
Q24672363 | Molecular pathology of ataxia telangiectasia |
Q34161464 | More forks on the road to replication stress recovery |
Q40264840 | Mre11-Rad50-Nbs1 complex is activated by hypertonicity. |
Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
Q24594847 | Multiple roles of ATM in monitoring and maintaining DNA integrity |
Q53030454 | Mutant cohesin drives chromosomal instability in early colorectal adenomas. |
Q34491545 | Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining |
Q34657712 | Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair |
Q30414341 | NBN phosphorylation regulates the accumulation of MRN and ATM at sites of DNA double-strand breaks |
Q34919494 | Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye. |
Q41920309 | Nijmegen breakage syndrome (NBS) with neurological abnormalities and without chromosomal instability |
Q37377461 | Nonaminoglycoside compounds induce readthrough of nonsense mutations |
Q35165183 | Nuclear GIT2 is an ATM substrate and promotes DNA repair |
Q41693676 | Our cells get stressed too! Implications for human disease |
Q64079819 | Overexpression of the cohesin-core subunit SMC1A contributes to colorectal cancer development |
Q36909835 | Oxidative stress, DNA damage and repair in heart failure patients after implantation of continuous flow left ventricular assist devices |
Q39827885 | PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. |
Q28243398 | PALB2: the hub of a network of tumor suppressors involved in DNA damage responses |
Q37258492 | PTIP regulates 53BP1 and SMC1 at the DNA damage sites |
Q28583434 | Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death |
Q55513225 | Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration. |
Q37950942 | Primary immunodeficiency diseases associated with neurologic manifestations |
Q34057826 | Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1. |
Q37190148 | RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites |
Q33658791 | Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice |
Q36542150 | Rad50S alleles of the Mre11 complex: questions answered and questions raised |
Q34307085 | Rapid flow cytometry-based structural maintenance of chromosomes 1 (SMC1) phosphorylation assay for identification of ataxia-telangiectasia homozygotes and heterozygotes |
Q36791604 | Rapid induction of chromatin-associated DNA mismatch repair proteins after MNNG treatment |
Q37120275 | Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network |
Q34972834 | Regulation of ATM/DNA-PKcs Phosphorylation by BRCA1-Associated BAAT1. |
Q34771336 | Regulation of DNA damage responses and cell cycle progression by hMOB2. |
Q39680532 | Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3. |
Q33886979 | Regulation of the DNA Damage Response to DSBs by Post-Translational Modifications |
Q37633137 | Regulation of the life cycle of HPVs by differentiation and the DNA damage response |
Q53549095 | Reoxygenation following hypoxia activates DNA-damage checkpoint signaling pathways that suppress cell-cycle progression in cultured human lymphocytes. |
Q41833935 | Repair versus Checkpoint Functions of BRCA1 Are Differentially Regulated by Site of Chromatin Binding |
Q37340387 | Replicating damaged DNA in eukaryotes |
Q34632186 | Requirement for NBS1 in the S phase checkpoint response to DNA methylation combined with PARP inhibition |
Q33725442 | Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences |
Q40292461 | Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. |
Q38018051 | Research on plants for the understanding of diseases of nuclear and mitochondrial origin |
Q35004980 | Ribosomal S6 Kinase 2 (RSK2) maintains genomic stability by activating the Atm/p53-dependent DNA damage pathway |
Q34427548 | Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models |
Q35155536 | Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancer |
Q40135858 | Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair |
Q39852067 | Roles of human AND-1 in chromosome transactions in S phase |
Q90119575 | SMC1 promotes proliferation and inhibits apoptosis through the NF‑κB signaling pathway in colorectal cancer |
Q36759739 | SMC1-mediated intra-S-phase arrest facilitates bocavirus DNA replication |
Q41876194 | SMC1A knockdown induces growth suppression of human lung adenocarcinoma cells through G1/S cell cycle phase arrest and apoptosis pathways in vitro |
Q40206464 | SMC1B is present in mammalian somatic cells and interacts with mitotic cohesin proteins. |
Q39104508 | SMC3 knockdown triggers genomic instability and p53-dependent apoptosis in human and zebrafish cells |
Q34709237 | SMRT compounds abrogate cellular phenotypes of ataxia telangiectasia in neural derivatives of patient-specific hiPSCs |
Q33870712 | SUMOylation and de-SUMOylation in response to DNA damage. |
Q28742198 | Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice |
Q48262221 | Sex differences in the late first trimester human placenta transcriptome |
Q42021074 | Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks |
Q45107461 | Sodium tungstate modulates ATM function upon DNA damage |
Q24300250 | Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates |
Q28235091 | Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks |
Q41035828 | Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis |
Q30480882 | Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis |
Q35597009 | Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells |
Q36712849 | The ATM signaling network in development and disease |
Q36547714 | The ATM-dependent DNA damage signaling pathway |
Q60932044 | The Emerging Role of Cohesin in the DNA Damage Response |
Q37526483 | The MRE11 complex: starting from the ends. |
Q34127693 | The MRN complex in double-strand break repair and telomere maintenance |
Q59360866 | The Major Tegument Protein of Bovine Herpesvirus 1, VP8, Interacts with DNA Damage Response Proteins and Induces Apoptosis |
Q33288787 | The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A. |
Q34227095 | The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor. |
Q37988601 | The Smc complexes in DNA damage response |
Q36178244 | The Use of Laser Microirradiation to Investigate the Roles of Cohesins in DNA Repair |
Q27014855 | The ancient and evolving roles of cohesin in gene expression and DNA repair |
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Q34110993 | The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage |
Q24317260 | The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells |
Q37761724 | The expanding universe of cohesin functions: a new genome stability caretaker involved in human disease and cancer. |
Q35831519 | The roles of cohesins in mitosis, meiosis, and human health and disease |
Q51029952 | The torments of the cohesin ring |
Q24652479 | The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response |
Q33369693 | Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation |
Q35966216 | Translational initiation regulated by ATM in dendritic cells development |
Q53626941 | Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. |
Q36293358 | Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response |
Q41888313 | Unwind and slow down: checkpoint activation by helicase and polymerase uncoupling |
Q36854964 | WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks |
Q37194235 | miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells |
Q39141299 | siRNA-mediated knockdown of SMC1A expression suppresses the proliferation of glioblastoma cells |
Q36258783 | γH2Ax Expression as a Potential Biomarker Differentiating between Low and High Grade Cervical Squamous Intraepithelial Lesions (SIL) and High Risk HPV Related SIL. |
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