| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1009446789 |
| P356 | DOI | 10.1038/NRM2514 |
| P698 | PubMed publication ID | 18813293 |
| P5875 | ResearchGate publication ID | 23279288 |
| P2093 | author name string | Martin F Lavin | |
| P2860 | cites work | ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway | Q22253899 |
| ATM-dependent phosphorylation of nibrin in response to radiation exposure | Q22254062 | ||
| Chk2 activation dependence on Nbs1 after DNA damage | Q24291406 | ||
| Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay | Q24291647 | ||
| SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint | Q24292395 | ||
| The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells | Q24294881 | ||
| ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex | Q24298863 | ||
| RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins | Q24300411 | ||
| RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly | Q24300428 | ||
| Large-scale characterization of HeLa cell nuclear phosphoproteins | Q24300834 | ||
| Extreme insulin resistance in ataxia telangiectasia: defect in affinity of insulin receptors | Q54584966 | ||
| FAT: a novel domain in PIK-related kinases | Q57444244 | ||
| Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity | Q59066708 | ||
| Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo | Q59098643 | ||
| Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways | Q61849111 | ||
| Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors | Q64387467 | ||
| No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation | Q64388457 | ||
| Incidence of cancer in 161 families affected by ataxia-telangiectasia | Q68073205 | ||
| On the nature of a defect in cells from individuals with ataxia-telangiectasia | Q70065595 | ||
| An unusual form of diabetes mellitus in ataxia telangiectasia | Q70135672 | ||
| Abnormal levels of UV-induced unscheduled DNA synthesis in ataxia telangiectasia cells after exposure to ionizing radiation | Q70379550 | ||
| Genomic Organization of the ATM gene | Q71139418 | ||
| Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis | Q72348085 | ||
| Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay | Q72670297 | ||
| ATAXIA-TELANGIECTASIA. ITS ASSOCIATION WITH A DEFECTIVE THYMUS, IMMUNOLOGICAL-DEFICIENCY DISEASE, AND MALIGNANCY | Q76773624 | ||
| The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair | Q24303369 | ||
| ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
| The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks | Q24311761 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome | Q24316811 | ||
| The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response | Q24316950 | ||
| A single ataxia telangiectasia gene with a product similar to PI-3 kinase | Q24323579 | ||
| Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage | Q24336328 | ||
| Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention | Q24563397 | ||
| Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex | Q24604459 | ||
| Immunoglobulin class switch recombination is impaired in Atm-deficient mice | Q24647660 | ||
| Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase | Q24653776 | ||
| ATM binds to beta-adaptin in cytoplasmic vesicles | Q24671480 | ||
| A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. | Q27919669 | ||
| The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder | Q28115238 | ||
| Substrate specificities and identification of putative substrates of ATM kinase family members | Q28141080 | ||
| Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products | Q28145751 | ||
| DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
| Human Rad50/Mre11 is a flexible complex that can tether DNA ends | Q28210390 | ||
| Interaction of FANCD2 and NBS1 in the DNA damage response | Q28215923 | ||
| Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks | Q28235091 | ||
| Interaction between ATM protein and c-Abl in response to DNA damage | Q28239339 | ||
| A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM | Q28270543 | ||
| Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA | Q28272303 | ||
| MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes | Q28274268 | ||
| The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species | Q28275116 | ||
| MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals | Q28292900 | ||
| Enhanced phosphorylation of p53 by ATM in response to DNA damage | Q28609838 | ||
| Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Q29614216 | ||
| Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
| A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia | Q29615437 | ||
| Activation of the cellular DNA damage response in the absence of DNA lesions | Q36953953 | ||
| Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres | Q37031809 | ||
| The DNA damage response pathways: at the crossroad of protein modifications | Q37034923 | ||
| Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. | Q37605239 | ||
| ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome | Q38307931 | ||
| Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species | Q38335343 | ||
| Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair | Q40135858 | ||
| Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. | Q40482010 | ||
| Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm. | Q40538990 | ||
| The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways | Q40750310 | ||
| Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. | Q40833566 | ||
| ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response | Q40875819 | ||
| Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway | Q40916856 | ||
| Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks | Q41090992 | ||
| The genetic defect in ataxia-telangiectasia | Q41464274 | ||
| Positional cloning of the gene for Nijmegen breakage syndrome | Q41926361 | ||
| Identification of ataxia telangiectasia heterozygotes, a cancer prone population | Q44028462 | ||
| Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation | Q44317026 | ||
| Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes. | Q47635097 | ||
| ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes. | Q52003055 | ||
| ATM-mediated response to DNA double strand breaks in human neurons derived from stem cells. | Q53582010 | ||
| The ATM-mediated DNA-damage response: taking shape. | Q53618038 | ||
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints | Q29617405 | ||
| Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation | Q29871427 | ||
| Systematic Discovery of In Vivo Phosphorylation Networks | Q30002403 | ||
| ATM associates with and phosphorylates p53: mapping the region of interaction | Q30175960 | ||
| Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase | Q30845708 | ||
| Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. | Q30868748 | ||
| Nijmegen breakage syndrome: consequences of defective DNA double strand break repair | Q33707289 | ||
| Localization of a portion of extranuclear ATM to peroxisomes | Q33880845 | ||
| Localization of an ataxia-telangiectasia gene to chromosome 11q22-23. | Q34169664 | ||
| Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage | Q34179079 | ||
| The MRN complex: coordinating and mediating the response to broken chromosomes | Q34250399 | ||
| Ataxia telangiectasia mutated expression and activation in the testis | Q34284463 | ||
| Active role for nibrin in the kinetics of atm activation | Q34519762 | ||
| ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. | Q34541828 | ||
| ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles | Q34546389 | ||
| Analysis of the ataxia telangiectasia mutated-mediated DNA damage response in murine cerebellar neurons. | Q34549273 | ||
| Rapid activation of ATM on DNA flanking double-strand breaks | Q34704848 | ||
| ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks | Q34722732 | ||
| An oncogene-induced DNA damage model for cancer development | Q34759268 | ||
| ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin | Q34801409 | ||
| Involvement of novel autophosphorylation sites in ATM activation | Q34972885 | ||
| ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. | Q34980532 | ||
| Sensing of intermediates in V(D)J recombination by ATM. | Q35005088 | ||
| Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM. | Q35640429 | ||
| ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks | Q35748584 | ||
| Ataxia-telangiectasia, an evolving phenotype | Q35848556 | ||
| Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis | Q35848561 | ||
| Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation | Q36057263 | ||
| Requirement of the MRN complex for ATM activation by DNA damage | Q36267304 | ||
| DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity | Q36316482 | ||
| Radiosensitivity in ataxia-telangiectasia: a new explanation | Q36419108 | ||
| H2AX haploinsufficiency modifies genomic stability and tumor susceptibility | Q36533572 | ||
| Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin | Q36562894 | ||
| Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin | Q36562899 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 759-769 | |
| P577 | publication date | 2008-10-01 | |
| P1433 | published in | Nature Reviews Molecular Cell Biology | Q1573120 |
| P1476 | title | Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer | |
| P478 | volume | 9 |
| Q42535570 | 'A mover and a shaker': 53BP1 allows DNA doublestrand breaks a chance to dance and unite |
| Q36129160 | 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells |
| Q37684399 | 53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation |
| Q39593027 | 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress |
| Q39352316 | 53BP1 promotes ATM activity through direct interactions with the MRN complex |
| Q39750906 | 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair |
| Q35038107 | A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase |
| Q52872513 | A Patient-Specific Stem Cell Model to Investigate the Neurological Phenotype Observed in Ataxia-Telangiectasia. |
| Q29614275 | A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations |
| Q42793623 | A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage |
| Q42234881 | A differential autophagy-dependent response to DNA double-strand breaks in bone marrow mesenchymal stem cells from sporadic ALS patients |
| Q24298271 | A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability |
| Q90592289 | A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers |
| Q34760557 | A mammalian functional-genetic approach to characterizing cancer therapeutics |
| Q33553010 | A novel and simple micro-irradiation technique for creating localized DNA double-strand breaks |
| Q30273849 | A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype. |
| Q42869599 | A role for vascular deficiency in retinal pathology in a mouse model of ataxia-telangiectasia |
| Q35842448 | A sensitive and quantitative polymerase chain reaction-based cell free in vitro non-homologous end joining assay for hematopoietic stem cells |
| Q34619774 | ATM activation in the presence of oxidative stress |
| Q39337933 | ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53. |
| Q53359826 | ATM and p53 are essential in the cell-cycle containment of DNA breaks during V(D)J recombination in vivo. |
| Q37059580 | ATM deficiency sensitizes mantle cell lymphoma cells to poly(ADP-ribose) polymerase-1 inhibitors |
| Q35893600 | ATM facilitates mouse gammaherpesvirus reactivation from myeloid cells during chronic infection |
| Q58804970 | ATM in breast and brain tumors: a comprehensive review |
| Q34692873 | ATM influences the efficiency of TCRβ rearrangement, subsequent TCRβ-dependent T cell development, and generation of the pre-selection TCRβ CDR3 repertoire |
| Q52727619 | ATM inhibition induces synthetic lethality and enhances sensitivity of PTEN-deficient breast cancer cells to cisplatin. |
| Q33667539 | ATM is down-regulated by N-Myc-regulated microRNA-421. |
| Q36941509 | ATM kinase inhibition preferentially sensitizes p53-mutant glioma to ionizing radiation |
| Q38886304 | ATM kinase sustains HER2 tumorigenicity in breast cancer |
| Q36913473 | ATM mutations in patients with hereditary pancreatic cancer |
| Q35279815 | ATM prevents DSB formation by coordinating SSB repair and cell cycle progression |
| Q39525325 | ATM protects against oxidative stress induced by oxidized low-density lipoprotein |
| Q37870855 | ATM protein kinase: the linchpin of cellular defenses to stress |
| Q35874528 | ATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis |
| Q35213158 | ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control |
| Q39766802 | ATM regulates a RASSF1A-dependent DNA damage response |
| Q34917270 | ATM release at resected double-strand breaks provides heterochromatin reconstitution to facilitate homologous recombination |
| Q41913571 | ATM specifically mediates repair of double-strand breaks with blocked DNA ends |
| Q39382156 | ATM, radiation, and the risk of second primary breast cancer |
| Q39189002 | ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair |
| Q34620780 | ATM- and NEMO-Dependent ELKS Ubiquitination Coordinates TAK1-Mediated IKK Activation in Response to Genotoxic Stress |
| Q26777987 | ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor |
| Q97522900 | ATM-associated signalling triggers the unfolded protein response and cell death in response to stress |
| Q38109386 | ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration. |
| Q33979941 | ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification |
| Q28488177 | ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response |
| Q24321489 | ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks |
| Q52087842 | ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses. |
| Q34249365 | ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition |
| Q24305338 | ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair |
| Q39035352 | ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair |
| Q38248933 | ATM: expanding roles as a chief guardian of genome stability |
| Q42742811 | ATMIN: a new tumor suppressor in developing B cells |
| Q41767755 | ATR maintains select progenitors during nervous system development |
| Q35533606 | Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency |
| Q33816985 | Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes |
| Q35403658 | Absence of Wip1 partially rescues Atm deficiency phenotypes in mice |
| Q34302728 | Activation of ATM-Chk2 by 16-dehydropregnenolone induces G1 phase arrest and apoptosis in HeLa cells |
| Q36297899 | Activation of the ATM-Snail pathway promotes breast cancer metastasis |
| Q64989893 | Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer. |
| Q35841601 | All stressed out without ATM kinase |
| Q28485299 | Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin |
| Q48649971 | Altered corticomotor-cerebellar integrity in young ataxia telangiectasia patients |
| Q35177611 | Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia |
| Q51017469 | Analyzing ATM Function by Electroporation of Endonucleases and Immunofluorescence Microscopy. |
| Q41823310 | Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements |
| Q34070170 | Apelin is required for non-neovascular remodeling in the retina. |
| Q35119681 | Arginine-rich cell-penetrating peptide dramatically enhances AMO-mediated ATM aberrant splicing correction and enables delivery to brain and cerebellum. |
| Q35134888 | Assessment of targeted and non-targeted responses in cells deficient in ATM function following exposure to low and high dose X-rays |
| Q58544582 | Association between ATM rs1801516 polymorphism and cancer susceptibility: a meta-analysis involving 12,879 cases and 18,054 controls |
| Q34438260 | Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients. |
| Q33800169 | Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells |
| Q39678828 | Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence |
| Q34659740 | Ataxia telangiectasia mutated influences cytochrome c oxidase activity |
| Q36397423 | Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection |
| Q47649609 | Ataxia telangiectasia syndrome: moonlighting ATM. |
| Q52620125 | Ataxia-telangiectasia: A new remitting form with a peculiar transcriptome signature. |
| Q33699336 | Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation |
| Q39526815 | Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spindle checkpoint |
| Q30498797 | Autophosphorylation and ATM activation: additional sites add to the complexity |
| Q40125358 | B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection |
| Q37336408 | Baculovirus F-box protein LEF-7 modifies the host DNA damage response to enhance virus multiplication |
| Q36414608 | Baculoviruses modulate a proapoptotic DNA damage response to promote virus multiplication |
| Q48320051 | Bone marrow transplantation improves the outcome of Atm-deficient mice through the migration of ATM-competent cells. |
| Q39813754 | CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines. |
| Q24622357 | CHK1 inhibitors in combination chemotherapy: thinking beyond the cell cycle |
| Q92890458 | CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition |
| Q58080400 | Cancer Diagnosis and Immunotherapy in the age of CRISPR |
| Q37627556 | Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more? |
| Q36084491 | Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability |
| Q42677506 | Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage |
| Q28250447 | Cell cycle kinases as therapeutic targets for cancer |
| Q24314465 | Cell cycle, CDKs and cancer: a changing paradigm |
| Q39631718 | Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21 |
| Q37351727 | Cell-free Xenopus egg extracts for studying DNA damage response pathways. |
| Q37648742 | Cellular radiosensitivity: how much better do we understand it? |
| Q38075860 | Cellular-signaling pathways unveil the carcinogenic potential of chemicals |
| Q36084372 | Changes in leukocyte gene expression profiles induced by antineoplastic chemotherapy. |
| Q47136901 | Characteristic Eye Movements in Ataxia-Telangiectasia-Like Disorder: An Explanatory Hypothesis |
| Q37500906 | Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance. |
| Q36626055 | Characterization of the role of Fhit in suppression of DNA damage |
| Q35089499 | Chfr and RNF8 synergistically regulate ATM activation |
| Q39550369 | Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional. |
| Q36754793 | Chloroquine increases phosphorylation of AMPK and Akt in myotubes. |
| Q41567794 | Chromatin modifiers and remodellers in DNA repair and signalling |
| Q38090114 | Chromatin remodeling at DNA double-strand breaks |
| Q37128128 | Chromatin remodeling finds its place in the DNA double-strand break response |
| Q41888460 | Chromosome instability and oxidative stress markers in patients with ataxia telangiectasia and their parents |
| Q37165291 | Chromosomes and cancer cells. |
| Q39286560 | Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation |
| Q88661083 | Clinically Applicable Inhibitors Impacting Genome Stability |
| Q38751436 | Co-inhibition of pol θ and HR genes efficiently synergize with cisplatin to suppress cisplatin-resistant lung cancer cells survival |
| Q34539510 | Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes |
| Q37291187 | Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass |
| Q26744443 | Connecting Malfunctioning Glial Cells and Brain Degenerative Disorders |
| Q35971460 | Coordinate to guard: crosstalk of phosphorylation, sumoylation, and ubiquitylation in DNA damage response. |
| Q42757411 | CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts |
| Q34184627 | Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages |
| Q24647070 | Cytoplasmic ATM in neurons modulates synaptic function |
| Q39210873 | DMAP1 is an essential regulator of ATM activity and function |
| Q45058549 | DNA Damage Response in Human Stem Cells and Neural Descendants |
| Q26743371 | DNA Damage and Repair in Schizophrenia and Autism: Implications for Cancer Comorbidity and Beyond |
| Q38118223 | DNA damage response: three levels of DNA repair regulation |
| Q38134064 | DNA damage sensing by the ATM and ATR kinases. |
| Q37995692 | DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. |
| Q88337377 | DNA damage-induced nuclear factor-kappa B activation and its roles in cancer progression |
| Q24314513 | DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger |
| Q37855947 | DNA double-strand break repair, immunodeficiency and the RIDDLE syndrome |
| Q34360500 | DNA double-strand break signaling and human disorders |
| Q90640801 | DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells |
| Q37630542 | DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis. |
| Q46267279 | DNM1L Variant Alters Baseline Mitochondrial Function and Response to Stress in a Patient with Severe Neurological Dysfunction |
| Q47659090 | Danger signals: Chemotherapy enhancers? |
| Q36608587 | Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer |
| Q34015533 | Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance |
| Q39261802 | Dexamethasone partially rescues ataxia telangiectasia-mutated (ATM) deficiency in ataxia telangiectasia by promoting a shortened protein variant retaining kinase activity |
| Q98178337 | Diabetes in Patients With Ataxia Telangiectasia: A National Cohort Study |
| Q37111110 | Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS |
| Q26997852 | Diseases associated with defective responses to DNA damage |
| Q37579636 | Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2. |
| Q54355658 | Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia. |
| Q39828855 | Downregulation of ATM Gene and Protein Expression in Canine Mammary Tumors. |
| Q37461477 | Doxorubicin induces the persistent activation of intracellular transglutaminase 2 that protects from cell death |
| Q39389281 | Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control |
| Q31090728 | Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention |
| Q33602897 | Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks |
| Q42325839 | Early B-cell-specific inactivation of ATM synergizes with ectopic CyclinD1 expression to promote pre-germinal center B-cell lymphomas in mice |
| Q28569081 | Effect of ionizing radiation in sensory ganglion neurons: organization and dynamics of nuclear compartments of DNA damage/repair and their relationship with transcription and cell cycle |
| Q53388774 | Effects of p21 deletion in mouse models of premature aging. |
| Q37525988 | Emerging connection between centrosome and DNA repair machinery |
| Q89723258 | Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency |
| Q34186270 | Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair |
| Q36238650 | Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53 |
| Q60920702 | Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle? |
| Q37185232 | Estrogen receptor α regulates ATM Expression through miRNAs in breast cancer |
| Q35881106 | Evaluation of fetal cell transplantation safety in treatment of diabetes: a three-year follow-up |
| Q42510070 | Evidence for the Deregulation of Protein Turnover Pathways in Atm-Deficient Mouse Cerebellum: An Organotypic Study |
| Q39492329 | Evidence of aberrant DNA damage response signalling but normal rates of DNA repair in dividing lymphoblasts from patients with schizophrenia |
| Q33572789 | Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells |
| Q27015719 | Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents |
| Q83572053 | Fanconi anemia |
| Q54218308 | Forward subtractive libraries containing genes transactivated by dexamethasone in ataxia-telangiectasia lymphoblastoid cells. |
| Q84218211 | From molecules and cells to diseases: West meets East for medical research in Tianjin |
| Q37643423 | From pathogenesis to treatment of chronic lymphocytic leukaemia |
| Q34977317 | From the rarest to the most common: insights from progeroid syndromes into skin cancer and aging. |
| Q21145799 | Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response |
| Q38221703 | Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress. |
| Q38199848 | Functional overlaps between XLF and the ATM-dependent DNA double strand break response |
| Q34995646 | Functional proteomics analysis to study ATM dependent signaling in response to ionizing radiation |
| Q33640584 | G2-phase chromosomal radiosensitivity of primary fibroblasts from hereditary retinoblastoma family members and some apparently normal controls |
| Q37454962 | GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny. |
| Q64388085 | GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells |
| Q42208604 | Generating SM(a)RTer compounds for translation termination suppression in A-T and other genetic disorders |
| Q38714822 | Genetically engineered livestock for biomedical models |
| Q47148140 | Genome integrity and disease prevention in the nervous system |
| Q38084862 | Genome maintenance and transcription integrity in aging and disease |
| Q52757700 | Genome maintenance functions of the INO80 chromatin remodeller. |
| Q29416994 | Genome-wide association study identifies three new melanoma susceptibility loci |
| Q36840576 | Genome-wide sequencing to identify the cause of hereditary cancer syndromes: with examples from familial pancreatic cancer |
| Q33892356 | Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome |
| Q45271940 | Growth hormone supplementation increased latency to tumourigenesis in Atm-deficient mice |
| Q49833263 | Growth hormone treatment in patients with ataxia telangiectasia |
| Q39588354 | HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents |
| Q33731091 | HMGNs, DNA repair and cancer |
| Q42403664 | Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas |
| Q37684554 | Having pancreatic cancer with tumoral loss of ATM and normal TP53 protein expression is associated with a poorer prognosis. |
| Q58323591 | Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex |
| Q92072154 | Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia |
| Q33711869 | Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis |
| Q92538283 | Hepatitis C Virus Mediated Inhibition of miR-181c Activates ATM Signaling and Promotes Hepatocyte Growth |
| Q33851085 | Hereditary pancreatic cancer: related syndromes and clinical perspective |
| Q43849854 | Heterotopic Purkinje cells in ataxia-telangiectasia |
| Q35823810 | High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX. |
| Q33692500 | High-resolution melting curve analysis for rapid detection of mutations in a Medaka TILLING library |
| Q37929048 | Histone deacetylase inhibitor: antineoplastic agent and radiation modulator |
| Q58796734 | Homeodomain Proteins Directly Regulate ATM Kinase Activity |
| Q28118451 | Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion |
| Q24302481 | IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway |
| Q35909521 | INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells |
| Q28487720 | Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential |
| Q97519186 | Identification of Two Novel Mutations in the ATM Gene from Patients with Ataxia-Telangiectasia by Whole Exome Sequencing |
| Q35002331 | Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven |
| Q36364721 | Image-Based High Content Screening: Automating the Quantification Process for DNA Damage-Induced Foci |
| Q26750420 | Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment |
| Q37439146 | Impaired DNA damage response--an Achilles' heel sensitizing cancer to chemotherapy and radiotherapy |
| Q37776824 | Importance of DNA damage checkpoints in the pathogenesis of human cancers |
| Q30434675 | Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion |
| Q34292978 | Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non-invasive breast cancer |
| Q38430674 | In vivo effects of dexamethasone on blood gene expression in ataxia telangiectasia. |
| Q33924107 | Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence |
| Q41135252 | Increased sensitivity to ionizing radiation by targeting the homologous recombination pathway in glioma initiating cells. |
| Q64116048 | Increased susceptibility of airway epithelial cells from ataxia-telangiectasia to S. pneumoniae infection due to oxidative damage and impaired innate immunity |
| Q30571118 | Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data |
| Q36861633 | Induced pluripotent stem cells from ataxia-telangiectasia recapitulate the cellular phenotype |
| Q51759185 | Inflammation, a significant player of Ataxia-Telangiectasia pathogenesis? |
| Q37861028 | Inherited mutations in breast cancer genes--risk and response |
| Q38005990 | Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2. |
| Q36190208 | Interaction between polymorphisms of DNA repair genes significantly modulated bladder cancer risk |
| Q30499891 | Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum |
| Q35737515 | Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks |
| Q54389409 | Iron loading and oxidative stress in the Atm-/- mouse liver. |
| Q39142926 | Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation |
| Q36145724 | Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice |
| Q37119667 | Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors |
| Q37384107 | Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance. |
| Q39080585 | LmHus1 is required for the DNA damage response in Leishmania major and forms a complex with an unusual Rad9 homologue. |
| Q47973030 | Loss of ATM in Airway Epithelial Cells Is Associated with Susceptibility to Oxidative Stress |
| Q34368454 | Loss of ATM kinase activity leads to embryonic lethality in mice |
| Q37281335 | Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas |
| Q38413284 | Loss of ataxia-telangiectasia-mutated protein expression correlates with poor prognosis but benefits from anthracycline-containing adjuvant chemotherapy in breast cancer |
| Q27853007 | Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines |
| Q35676851 | Low ATM protein expression in malignant tumor as well as cancer-associated stroma are independent prognostic factors in a retrospective study of early-stage hormone-negative breast cancer |
| Q38864825 | Low-dose radiation may be a novel approach to enhance the effectiveness of cancer therapeutics |
| Q37666955 | MET signaling promotes DNA repair and radiation resistance in glioblastoma stem-like cells |
| Q47938130 | MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress |
| Q92730744 | Maintenance BEZ235 Treatment Prolongs the Therapeutic Effect of the Combination of BEZ235 and Radiotherapy for Colorectal Cancer |
| Q48895419 | Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain |
| Q33661490 | Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control |
| Q34181806 | Mechanism-based screen establishes signalling framework for DNA damage-associated G1 checkpoint response |
| Q34224906 | Metastasis of neuroendocrine tumors are characterized by increased cell proliferation and reduced expression of the ATM gene |
| Q35645149 | Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer |
| Q45961719 | Metformin: a cheap and well-tolerated drug that provides benefits for viral infections. |
| Q61450646 | Methodologies for Improving HDR Efficiency |
| Q38085906 | MicroRNAs in the ionizing radiation response and in radiotherapy |
| Q37823782 | MicroRNAs: new players in the DNA damage response |
| Q34824191 | Microarray analysis of XOPS-mCFP zebrafish retina identifies genes associated with rod photoreceptor degeneration and regeneration. |
| Q24630465 | Mitochondrial dysfunction in ataxia-telangiectasia |
| Q28117038 | Molecular and Functional Characterization of a Cohort of Spanish Patients with Ataxia-Telangiectasia |
| Q86483631 | Molecular basis of chronic lymphocytic leukemia diagnosis and prognosis |
| Q39825566 | Molecular genetic characterization of Drosophila ATM conserved functional domains. |
| Q37009650 | Molecular imaging of the ATM kinase activity |
| Q38224260 | Molecular mechanisms of low dose ionizing radiation-induced hormesis, adaptive responses, radioresistance, bystander effects, and genomic instability |
| Q34990657 | Molecular parameters of hyperthermia for radiosensitization |
| Q52772554 | Monitoring DNA Repair Consequences of ATM Signaling Using Simultaneous Fluorescent Readouts. |
| Q51017410 | Monitoring the ATM-Mediated DNA Damage Response in the Cerebellum Using Organotypic Cultures. |
| Q42094650 | Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors |
| Q36033084 | Motor pathway degeneration in young ataxia telangiectasia patients: A diffusion tractography study. |
| Q34447472 | Mouse models of inherited cancer syndromes |
| Q55052114 | Mre11: roles in DNA repair beyond homologous recombination. |
| Q92120656 | Multiparametric cerebellar imaging and clinical phenotype in childhood ataxia telangiectasia |
| Q36438934 | Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development |
| Q24594847 | Multiple roles of ATM in monitoring and maintaining DNA integrity |
| Q51062791 | Myosin 16 levels fluctuate during the cell cycle and are downregulated in response to DNA replication stress. |
| Q34015940 | NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes |
| Q41477550 | NF-κB-dependent DNA damage-signaling differentially regulates DNA double-strand break repair mechanisms in immature and mature human hematopoietic cells |
| Q38759129 | New agents on the horizon in gastric cancer |
| Q34037422 | New mutations in the ATM gene and clinical data of 25 AT patients |
| Q38184454 | Next-generation sequencing for inherited breast cancer risk: counseling through the complexity |
| Q33854272 | Non-homologous end joining: emerging themes and unanswered questions |
| Q26801745 | Not All Next Generation Sequencing Diagnostics are Created Equal: Understanding the Nuances of Solid Tumor Assay Design for Somatic Mutation Detection |
| Q37746495 | Nuclear ataxias. |
| Q39270104 | Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response |
| Q50602552 | Nutritional status of patients with ataxia-telangiectasia: A case for early and ongoing nutrition support and intervention. |
| Q37018223 | Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. |
| Q39231616 | Oral-facial-digital syndrome type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network |
| Q55457072 | Orally bioavailable and blood-brain-barrier penetrating ATM inhibitor (AZ32) radiosensitizes intracranial gliomas in mice. |
| Q36347755 | Orphan nuclear receptor small heterodimer partner negatively regulates growth hormone-mediated induction of hepatic gluconeogenesis through inhibition of signal transducer and activator of transcription 5 (STAT5) transactivation |
| Q36589947 | Ovarian cancer: in search of better marker systems based on DNA repair defects |
| Q35844884 | Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development |
| Q37132896 | Oxidants, metabolism, and stem cell biology |
| Q35816507 | Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation |
| Q82475941 | Oxidative stress: ATM bonds under stress |
| Q97533420 | Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation |
| Q28741688 | PARP inhibitor treatment in ovarian and breast cancer |
| Q47803583 | PIKKing a way to regulate inflammation |
| Q93187672 | PKI-587 enhances chemosensitivity of oxaliplatin in hepatocellular carcinoma through suppressing DNA damage repair pathway (NHEJ and HR) and PI3K/AKT/mTOR pathway |
| Q36706631 | Panel testing reveals nonsense and missense CDH1 mutations in families without hereditary diffuse gastric cancer |
| Q90208185 | Pharmacological inhibition of ataxia-telangiectasia mutated exacerbates acute kidney injury by activating p53 signaling in mice |
| Q51017418 | Phenotypic Analysis of ATM Protein Kinase in DNA Double-Strand Break Formation and Repair. |
| Q39414954 | Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer |
| Q37505495 | Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation |
| Q34308770 | Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer |
| Q31163246 | Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss |
| Q38137764 | Predictive biomarkers for cancer therapy with PARP inhibitors. |
| Q43809547 | Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study |
| Q36562231 | Prevalence of deleterious ATM germline mutations in gastric cancer patients |
| Q49184571 | Promoter Hypermethylation of the ATM Gene as a Novel Biomarker for Breast Cancer |
| Q34762217 | Promoter methylation of tumor suppressor genes in pre-neoplastic lesions; potential marker of disease recurrence. |
| Q38125901 | Proteasome-dependent degradation of replisome components regulates faithful DNA replication |
| Q33705076 | Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX. |
| Q36186917 | Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity. |
| Q30498312 | Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice |
| Q38434020 | Quantitative Analysis of Cellular Senescence in Culture and In Vivo |
| Q27318630 | R-loops in proliferating cells but not in the brain: implications for AOA2 and other autosomal recessive ataxias |
| Q39008812 | RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. |
| Q37914341 | RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response. |
| Q33658791 | Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice |
| Q42109676 | Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice |
| Q34300733 | Radiation therapy and adjuvant chemotherapy in a patient with a malignant glioneuronal tumor and underlying ataxia telangiectasia: a case report and review of the literature |
| Q92525683 | Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase |
| Q36280683 | Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase |
| Q36269199 | Radiation-sensitive severe combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation--what to do? |
| Q37694756 | Radiosensitizing effect of lapatinib in human epidermal growth factor receptor 2-positive breast cancer cells |
| Q39814876 | Re-sensitization of radiation resistant colorectal cancer cells to radiation through inhibition of AMPK pathway |
| Q36745078 | Reactive Oxygen Species (ROS)-Activated ATM-Dependent Phosphorylation of Cytoplasmic Substrates Identified by Large-Scale Phosphoproteomics Screen |
| Q36929407 | Recent progress in mouse models for tumor suppressor genes and its implications in human cancer |
| Q59791546 | Reconstitution of the Ataxia-Telangiectasia Cellular Phenotype With Lentiviral Vectors |
| Q42801717 | Reconstitution of the cellular response to DNA damage in vitro using damage-activated extracts from mammalian cells |
| Q38771420 | Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress |
| Q37607081 | Rejuvenating the immune system in rheumatoid arthritis |
| Q37993652 | Replication fork dynamics and the DNA damage response. |
| Q36095690 | Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks |
| Q42717522 | Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases |
| Q41229658 | Requirement of the ATM/p53 tumor suppressor pathway for glucose homeostasis |
| Q35911163 | Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts |
| Q33871983 | Role of ataxia telangiectasia mutated in insulin signalling of muscle-derived cell lines and mouse soleus |
| Q36997722 | Role of leukemia inhibitory factor in nasopharyngeal carcinogenesis |
| Q55613070 | Role of the DNA Damage Response in Human Papillomavirus RNA Splicing and Polyadenylation. |
| Q90360119 | SMG1 heterozygosity exacerbates haematopoietic cancer development in Atm null mice by increasing persistent DNA damage and oxidative stress |
| Q33870712 | SUMOylation and de-SUMOylation in response to DNA damage. |
| Q24301299 | SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death |
| Q34909319 | SV40 DNA replication: from the A gene to a nanomachine |
| Q55223567 | Second-line therapy in advanced upper gastrointestinal cancers: current status and new prospects. |
| Q28088672 | Senescence from G2 arrest, revisited |
| Q33824877 | Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair |
| Q37407122 | Sensitization strategies in lung cancer |
| Q35682034 | Severe reaction to radiotherapy for breast cancer as the presenting feature of ataxia telangiectasia |
| Q42155621 | Site promiscuity of coliphage HK022 integrase as a tool for gene therapy |
| Q33883063 | Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response |
| Q36455995 | Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1. |
| Q53031706 | Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair. |
| Q35908249 | Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase |
| Q51017436 | Statistical Analysis of ATM-Dependent Signaling in Quantitative Mass Spectrometry Phosphoproteomics. |
| Q34685564 | Stem cells: the pursuit of genomic stability |
| Q92003387 | Structural insights into the activation of ATM kinase |
| Q33779587 | Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin |
| Q35051154 | Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations |
| Q36579126 | TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q. |
| Q43553683 | TCTP directly regulates ATM activity to control genome stability and organ development in Drosophila melanogaster. |
| Q37389151 | Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours |
| Q28287476 | Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation |
| Q34138796 | Targeting nonhomologous end-joining through epidermal growth factor receptor inhibition: rationale and strategies for radiosensitization |
| Q40972934 | Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants |
| Q36062088 | Targeting the ataxia telangiectasia mutated pathway for effective therapy against hirsutine-resistant breast cancer cells |
| Q43149067 | Tdp1 protects against oxidative DNA damage in non-dividing fission yeast |
| Q34051060 | Telomeres and immunological diseases of aging |
| Q36781235 | Tetraploidization or autophagy: The ultimate fate of senescent human endometrial stem cells under ATM or p53 inhibition |
| Q39776763 | The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation |
| Q37955496 | The ATM protein kinase and cellular redox signaling: beyond the DNA damage response |
| Q38088935 | The ATM protein kinase: regulating the cellular response to genotoxic stress, and more |
| Q44132170 | The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells |
| Q36664049 | The ATR barrier to replication-born DNA damage. |
| Q42601412 | The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect |
| Q35635008 | The DNA damage response induces IFN. |
| Q34009427 | The DNA-damage response: new molecular insights and new approaches to cancer therapy |
| Q40497616 | The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover |
| Q35679564 | The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. |
| Q92404685 | The German National Registry of Primary Immunodeficiencies (2012-2017) |
| Q35962395 | The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation |
| Q37782351 | The Role of the DNA Damage Response Mechanisms after Low-Dose Radiation Exposure and a Consideration of Potentially Sensitive Individuals |
| Q42565688 | The atm-1 gene is required for genome stability in Caenorhabditis elegans |
| Q34707456 | The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double-strand break repair. |
| Q38868502 | The cell cycle checkpoint inhibitors in the treatment of leukemias. |
| Q84743172 | The dark side of the oxidative force in angiogenesis |
| Q35763894 | The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses |
| Q37971870 | The dynamic interplay in chromatin remodeling factors polycomb and trithorax proteins in response to DNA damage |
| Q42552591 | The effect of ATM knockdown on ionizing radiation-induced neuronal cell cycle reentry in Drosophila |
| Q39084654 | The epithelium specific cell cycle regulator 14-3-3sigma is required for preventing entry into mitosis following ultraviolet B. |
| Q41891513 | The genomics of lung adenocarcinoma: opportunities for targeted therapies |
| Q38056496 | The heterochromatic barrier to DNA double strand break repair: how to get the entry visa |
| Q41375377 | The mef/elf4 transcription factor fine tunes the DNA damage response |
| Q50017359 | The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy |
| Q34025989 | The phenotypic radiation resistance of CD44+/CD24(-or low) breast cancer cells is mediated through the enhanced activation of ATM signaling |
| Q34444598 | The tumor-immune microenvironment and response to radiation therapy |
| Q34061440 | The versatile functions of ATM kinase |
| Q59198405 | Therapeutic targets and investigated treatments for Ataxia-Telangiectasia |
| Q37693590 | Tip60: connecting chromatin to DNA damage signaling |
| Q36335123 | Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion |
| Q37906909 | Transcriptional modulation induced by ionizing radiation: p53 remains a central player |
| Q57073720 | Treatment of Granulomas in Patients With Ataxia Telangiectasia |
| Q26745686 | Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy |
| Q35134937 | Tug of war between survival and death: exploring ATM function in cancer |
| Q35410801 | Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses |
| Q53529113 | Tumor suppressor miR-145 reverses drug resistance by directly targeting DNA damage-related gene RAD18 in colorectal cancer. |
| Q36293358 | Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response |
| Q88564382 | Tyrosyl-DNA Phosphodiesterase I a critical survival factor for neuronal development and homeostasis |
| Q64081710 | UFL1 promotes histone H4 ufmylation and ATM activation |
| Q36599308 | USP-11 as a predictive and prognostic factor following neoadjuvant therapy in women with breast cancer |
| Q35768395 | Underexpression and abnormal localization of ATM products in ataxia telangiectasia patients bearing ATM missense mutations |
| Q43061574 | Update on the management of the immunodeficiency in ataxia-telangiectasia |
| Q43596090 | Variant ataxia telangiectasia: clinical and molecular findings and evaluation of radiosensitive phenotypes in a patient and relatives |
| Q30423128 | Variants in activators and downstream targets of ATM, radiation exposure, and contralateral breast cancer risk in the WECARE study |
| Q33760096 | Variants in the ATM-CHEK2-BRCA1 axis determine genetic predisposition and clinical presentation of papillary thyroid carcinoma |
| Q34335765 | WEE1 tyrosine kinase, a novel epigenetic modifier |
| Q64260753 | as a Model to Study the Multiple Phenotypes, Related to Genome Stability of the Fragile-X Syndrome |
| Q42790602 | c-Abl tyrosine kinase in the DNA damage response: cell death and more |
| Q37697004 | miR-151-5p, targeting chromatin remodeler SMARCA5, as a marker for the BRCAness phenotype |
| Q36729533 | miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. |
| Q34269240 | microRNA expression and biogenesis in cellular response to ionizing radiation |
| Q34991379 | p38MAPK and MK2 pathways are important for the differentiation-dependent human papillomavirus life cycle |
| Q36638226 | p53 centrosomal localization diagnoses ataxia-telangiectasia homozygotes and heterozygotes |
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