| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1019226312 |
| P356 | DOI | 10.1038/258427A0 |
| P953 | full work available at URL | http://www.nature.com/articles/258427a0 |
| http://www.nature.com/articles/258427a0.pdf | ||
| P698 | PubMed publication ID | 1196376 |
| P2093 | author name string | A. R. Lehmann | |
| B. A. Bridges | |||
| S. Stevens | |||
| C. F. Arlett | |||
| S. A. Harcourt | |||
| D. G. Harnden | |||
| A. M. Taylor | |||
| P2860 | cites work | Postreplication repair of DNA in ultraviolet-irradiated mammalian cells | Q44587841 |
| Repair of x-ray damage in DNA of cultivated cells from patients having xeroderma pigmentosum | Q44938011 | ||
| Radiosensitivity in ataxia-telangiectasia | Q44997480 | ||
| Double-strand breaks in the DNA of a mammalian cell after X-irradiation | Q64390853 | ||
| In vitro chromosomal radiosensitivity in "chromosomal breakage syndromes" | Q69558534 | ||
| Ataxia-telangiectasia | Q70392723 | ||
| Ataxia telangiectasia. Neoplasia, untoward response to x-irradiation, and tuberous sclerosis | Q72348085 | ||
| P433 | issue | 5534 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ataxia telangiectasia | Q387082 |
| P304 | page(s) | 427-429 | |
| P577 | publication date | 1975-12-01 | |
| 1975-12-04 | |||
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity | |
| P478 | volume | 258 |
| Q46675567 | A Human Subject with A New Defect in Repair of Ultraviolet Damage |
| Q38558566 | A New Era of Low-Dose Radiation Epidemiology |
| Q70683889 | A case of pure red cell aplasia with a high incidence of spontaneous chromosome breakage: a possible X-ray sensitive syndrome |
| Q33668827 | A clinical study of a family with Cockayne's syndrome |
| Q40763320 | A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells |
| Q45277010 | A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis |
| Q35882136 | A high frequency of distinct ATM gene mutations in ataxia-telangiectasia |
| Q36832587 | A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines |
| Q24323298 | A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene |
| Q34393856 | A precocious cerebellar ataxia and frequent Fever episodes in a 16-month-old infant revealing ataxia-telangiectasia syndrome. |
| Q40514077 | A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint |
| Q50920906 | A sensitive assay for detecting hypersensitivity to ionizing radiation in lymphoblastoid lines from patients with duchenne muscular dystrophy and primary neuronal degenerations |
| Q28486683 | ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells |
| Q48864956 | ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture |
| Q40631562 | ATM's leucine-rich domain and adjacent sequences are essential for ATM to regulate the DNA damage response |
| Q34425440 | ATM, a central controller of cellular responses to DNA damage. |
| Q39382156 | ATM, radiation, and the risk of second primary breast cancer |
| Q34142115 | ATM-NF-kappaB connection as a target for tumor radiosensitization |
| Q33722965 | ATM: the product of the gene mutated in ataxia-telangiectasia |
| Q40662922 | ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation |
| Q41135787 | Abrogation of radioresistance in glioblastoma stem-like cells by inhibition of ATM kinase |
| Q36431591 | Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy |
| Q40530947 | Accumulation of the common mitochondrial DNA deletion induced by ionizing radiation |
| Q40783205 | Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53. |
| Q73090152 | Altered apoptotic profiles in irradiated patients with increased toxicity |
| Q48649971 | Altered corticomotor-cerebellar integrity in young ataxia telangiectasia patients |
| Q33620910 | An ATM homologue from Arabidopsis thaliana: complete genomic organisation and expression analysis. |
| Q34996684 | An altered apurinic DNA endonuclease activity in group A and group D xeroderma pigmentosum fibroblasts |
| Q42151249 | An enzyme activity in normal and ataxia telangiectasia cell lines which is involved in the repair of gamma-irradiation-induced DNA damage |
| Q72518851 | An in vitro investigation of genetic susceptibility to cancer in diploid fibroblasts from retinoblastoma patients |
| Q41186496 | An instance of clinical radiation morbidity and cellular radiosensitivity, not associated with ataxia-telangiectasia |
| Q42806662 | An ionizing radiation-sensitive mutant of CHO cells: irs-20. III. Chromosome aberrations, DNA breaks and mitotic delay |
| Q70359030 | Analysis of CD3 antigen expression in patients with ataxia-telangiectasia |
| Q45868414 | Antisense ATM gene therapy: a strategy to increase the radiosensitivity of human tumors |
| Q40572699 | Apurinic DNA endonuclease activities in repair-deficient human cell lines |
| Q40200036 | Apurinic and/or apyrimidinic endonuclease activity in ataxia telangiectasia cell extracts |
| Q41928463 | Ataxia telangiectasia and lymphoma: an indication for individualized chemotherapy dosing--report of treatment in a highly inbred Arab family |
| Q36713937 | Ataxia telangiectasia-mutated dependent DNA damage checkpoint functions regulate gene expression in human fibroblasts. |
| Q38323889 | Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase |
| Q34986282 | Ataxia telangiectasia. Evaluation of radiosensitivity in cultured skin fibroblasts as a diagnostic test |
| Q66930380 | Ataxia telangiectasia: Further considerations of the evidence for single strand break repair |
| Q45254825 | Ataxia telangiectasia: The effects of chemical mutagens and x-rays on sister chromatid exchanges in blood lymphocytes |
| Q40495932 | Ataxia telangiectasia: an anomaly in DNA replication after irradiation |
| Q38390957 | Ataxia-telangiectasia or Louis-Bar syndrome. |
| Q33697357 | Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene |
| Q39761489 | Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect |
| Q35599431 | Ataxia-telangiectasia: diagnosis and treatment |
| Q37278036 | Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer |
| Q39187349 | Ataxia-telangiectasia: recommendations for multidisciplinary treatment |
| Q72651457 | Bleomycin induced inhibition of DNA synthesis in ataxia-telangiectasia cell lines |
| Q48784313 | Bryn Bridges and mutagenesis: exploring the intellectual space. |
| Q28393308 | Cancer risks associated with external radiation from diagnostic imaging procedures |
| Q40311640 | Cancer-associated human genetic diseases with defects in DNA repair |
| Q28483080 | Ccdc94 protects cells from ionizing radiation by inhibiting the expression of p53 |
| Q48249297 | Cell culture study on neurofibromatosis. |
| Q33918824 | Cell cycle dependent DNA break increase in ataxia telangiectasia lymphoblasts after radiation exposure |
| Q40442266 | Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective |
| Q38524035 | Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after x-irradiation |
| Q60300970 | Cell type-dependent bimodal p53 activation engenders a dynamic mechanism of chemoresistance |
| Q77954362 | Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase |
| Q42581823 | Cellular hypersensitivity to ionising radiation in Friedreich's ataxia |
| Q40580197 | Cellular radiosensitivity in ataxia-telangiectasia |
| Q37648742 | Cellular radiosensitivity: how much better do we understand it? |
| Q44032986 | Cellular studies on retinoblastoma |
| Q49144645 | Central nervous system dysmyelination in PIBI(D)S syndrome: a further case |
| Q33930435 | Cerebral abnormalities in adults with ataxia-telangiectasia |
| Q39997594 | Chemical mutagen hypersensitivity in ataxia telangiectasia |
| Q33382608 | Chemoimmunotherapy may overcome the adverse prognostic significance of 11q deletion in previously untreated patients with chronic lymphocytic leukemia |
| Q40976743 | Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells |
| Q41567794 | Chromatin modifiers and remodellers in DNA repair and signalling |
| Q40924881 | Chromosomal abnormalities in human neoplasia (author's transl) |
| Q72997932 | Chromosomal breakage correlates with delayed lethality in normal and ataxia telangiectasia cell lines treated with bleomycin |
| Q41525226 | Chromosomal breakage, endomitosis, endoreduplication, and hypersensitivity toward radiomimetric and alkylating agents: A possible new autosomal recessive mutation in a girl with craniosynostosis and microcephaly |
| Q38361598 | Chromosomal instability and radiosensitivity in myelodysplastic syndrome cells |
| Q66985287 | Chromosomal radiosensitivity of ataxia telangiectasia cells at different cell cycle stages |
| Q41110946 | Chromosome instability with bleomycin and X-ray hypersensitivity in a boy with Nijmegen breakage syndrome. |
| Q39849133 | Chromosomes and Neoplasia |
| Q38963019 | Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target? |
| Q38919291 | Classic ataxia-telangiectasia in a Sudanese boy: Case report and review of the literature |
| Q38367392 | Clinical interest in determinations of cellular radiation sensitivity. |
| Q40993982 | Comparison of high dose rate, low dose rate, and high dose rate fractionated radiation for optimizing differences in radiosensitivities in vitro |
| Q52429391 | Comparison of survival and unscheduled DNA synthesis between an insect and a mammalian cell line following x-ray treatments |
| Q41638580 | Complementation of a DNA repair deficiency in six human tumor cell lines by chromosome 11 |
| Q30408244 | Comprehensive profiling of radiosensitive human cell lines with DNA damage response assays identifies the neutral comet assay as a potential surrogate for clonogenic survival |
| Q37656781 | Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells |
| Q35405693 | Creative blocks: cell-cycle checkpoints and feedback controls |
| Q35885502 | Cultured diploid fibroblasts from patients with the nevoid basal cell carcinoma syndrome are hypersensitive to killing by ionizing radiation. |
| Q42490454 | Cultured skin keratinocytes from both normal individuals and basal cell naevus syndrome patients are more resistant to gamma-rays and UV light compared with cultured skin fibroblasts. |
| Q45962060 | Cytogenetic investigations in a family with ataxia telangiectasia. |
| Q40437588 | DNA Repair Defects and Chromosome Instability Disorders |
| Q35340166 | DNA Repair and Human Disease |
| Q40712025 | DNA Single-strand Break Repair in Cultured Insect and Mammalian Cells after X-irradiation |
| Q40719929 | DNA damage response pathway in radioadaptive response |
| Q94474304 | DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer |
| Q33763235 | DNA damage responses in central nervous system and age-associated neurodegeneration |
| Q39766011 | DNA damage, DNA repair and the genetic basis of Alzheimer's disease |
| Q40457853 | DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM. |
| Q40573478 | DNA polymerases alpha beta and gamma in inherited diseases affecting DNA repair |
| Q70160564 | DNA repair |
| Q36492818 | DNA repair and mutagenesis in mammalian cells |
| Q37368873 | DNA repair deficiency and neurological disease |
| Q40294412 | DNA repair in human diseases |
| Q29615572 | DNA repair pathways as targets for cancer therapy |
| Q47883620 | DNA repair, genome stability and cancer: a historical perspective |
| Q72924091 | DNA-repair synthesis in ataxia telangiectasia lymphoblastoid cells |
| Q30759422 | Damage and repair of nerve cell DNA in toxic stress |
| Q47672774 | Defect in Radiation Signal Transduction in Ataxia-telangiectasia |
| Q71521989 | Defective DNA repair and increased lethality in ataxia telangiectasia cells exposed to 4-nitroquinoline-1-oxide |
| Q43789777 | Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts |
| Q42823396 | Defective recovery from potentially lethal damage in some human fibroblast cell strains |
| Q41945129 | Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains |
| Q59058272 | Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum |
| Q35821428 | Defining molecular and cellular responses after low and high linear energy transfer radiations to develop biomarkers of carcinogenic risk or therapeutic outcome |
| Q36292970 | Demonstration of increased collagen synthesis in irradiated human skin in vivo |
| Q28590967 | Detection of Acute Radiation Sickness: A Feasibility Study in Non-Human Primates Circulating miRNAs for Triage in Radiological Events |
| Q37295779 | Development of a prediction model for radiosensitivity using the expression values of genes and long non-coding RNAs. |
| Q69873393 | Diagnosis of ataxia-telangiectasia by T-lymphocyte cloning assay |
| Q36953970 | Differences in DNA Repair Capacity, Cell Death and Transcriptional Response after Irradiation between a Radiosensitive and a Radioresistant Cell Line. |
| Q41564882 | Different cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid cell lines derived from a single donor |
| Q41931896 | Differential level of DSB repair fidelity effected by nuclear protein extracts derived from radiosensitive and radioresistant human tumour cells |
| Q37692283 | Differential radiosensitivity phenotypes of DNA-PKcs mutations affecting NHEJ and HRR systems following irradiation with gamma-rays or very low fluences of alpha particles |
| Q40842085 | Differential responses of Chinese hamster mutagen sensitive cell lines to low and high concentrations of calicheamicin and neocarzinostatin |
| Q35202965 | Disorders of B cells and helper T cells in the pathogenesis of the immunoglobulin deficiency of patients with ataxia telangiectasia |
| Q40296821 | Dna repair: pathways and defects |
| Q40212424 | Dominant susceptibility to cancer in man. |
| Q35730250 | Drosophila ATR in double-strand break repair |
| Q74812598 | Editorial radiotherapy and oncology 2002: predictive assays for normal tissue damage |
| Q52640780 | Effect of DNA Repair on Aging of Transgenic Drosophila melanogaster: I. mei-41 Locus |
| Q40726132 | Effect of Ionizing Radiations on the Life Span of Non-transformed Human Fibroblasts |
| Q70588725 | Effect of caffeine in G2 on X-ray-induced chromosomal aberrations and mitotic inhibition in ataxia telangiectasia fibroblast and lymphoblastoid cells |
| Q40482010 | Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells. |
| Q52552301 | Effect ofAtmDisruption on Spontaneously Arising and Radiation-Induced Deletion Mutations in Mouse Liver |
| Q89723258 | Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency |
| Q66982061 | Endonucleolytic activity for γ-irradiated DNA in normal and ataxia telangiectasia fibroblast cell extracts |
| Q40672836 | Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration |
| Q41420971 | Enhanced chromosomal response of ataxia-telangiectasia cells to specific types of DNA double-strand breaks |
| Q43978558 | Enhanced expression of procollagenase in ataxia-telangiectasia and xeroderma pigmentosum fibroblasts |
| Q41361584 | Enzymatic restriction of mammalian cell DNA: evidence for double-strand breaks as potentially lethal lesions |
| Q38306307 | Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia. |
| Q44445334 | Erythrocyte superoxide dismutase in ataxia telangiectasia and Fanconi's anaemia |
| Q41713439 | Establishment of a novel immortalized cell line from ataxia telangiectasia fibroblasts and its use for the chromosomal assignment of radiosensitivity gene |
| Q37061745 | Estrogen protects against radiation-induced cataractogenesis |
| Q33330300 | Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation |
| Q57618644 | Evidence for a Positive Correlation between in Vitro Radiosensitivity of Normal Human Skin Fibroblasts and the Occurrence of Subcutaneous Fibrosis after Radiotherapy |
| Q41588382 | Evidence of different complementation groups amongst human genetic disorders characterized by radiosensitivity |
| Q42784530 | Familial susceptibility to cancer. |
| Q33478170 | Familial thrombocytopenia associated with platelet autoantibodies and chromosome breakage |
| Q44277817 | Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis |
| Q35853237 | Fine mapping of the chromosome 11q22-23 region using PFGE, linkage and haplotype analysis; localization of the gene for ataxia telangiectasia to a 5cM region flanked by NCAM/DRD2 and STMY/CJ52.75, phi 2.22 |
| Q34071802 | Four radiation hypersensitivity cases and their implications for clinical radiotherapy |
| Q41659051 | Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress |
| Q72628463 | Gamma-ray induced inhibition of DNA synthesis in ataxia telangiectasia fibroblasts is a function of excision repair capacity |
| Q36541173 | Gastrointestinal radiation injury: symptoms, risk factors and mechanisms |
| Q58348309 | Gene Carrier Detection in Retinoblastoma |
| Q33923372 | Genetic and biochemical studies with ataxia telangiectasia. A review |
| Q44620958 | Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study |
| Q45803483 | Genetic recombination of Herpes simplex virus, the role of the host cell and UV-irradiation of the virus |
| Q37782809 | Genetics and Etiology of Human Cancer |
| Q21183971 | Genetics and genomics of radiotherapy toxicity: towards prediction |
| Q30500345 | Genetics of neoplasia--impact of ecogenetics on oncogenesis. A review |
| Q47148140 | Genome integrity and disease prevention in the nervous system |
| Q37705828 | Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM. |
| Q41838838 | HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition. |
| Q24548232 | HRAD1 and MRAD1 encode mammalian homologues of the fission yeast rad1(+) cell cycle checkpoint control gene |
| Q34038406 | HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses |
| Q34390257 | Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer? |
| Q23915190 | Heterogeneity in the clastogenic response to X-rays in lymphocytes from ataxia-telangiectasia heterozygotes and controls |
| Q72785292 | Heterogeneity of immunological abnormalities in ataxia-telangiectasia |
| Q43849854 | Heterotopic Purkinje cells in ataxia-telangiectasia |
| Q36115517 | Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients |
| Q38348222 | Heterozygous ATM mutations do not contribute to early onset of breast cancer |
| Q34379090 | High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines |
| Q40767831 | High frequency of deletions at the hypoxanthine-guanine phosphoribosyltransferase locus in an ataxia-telangiectasia lymphoblastoid cell line irradiated with gamma-rays |
| Q30413950 | Homozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks |
| Q45292967 | Host cell reactivation of sunlamp-exposed adenovirus in fibroblasts from patients with Bloom's syndrome, ataxia telangiectasia, and Huntington's disease |
| Q45102274 | Host cell reactivation of uv- and X-ray-damaged herpes simplex virus by epstein-barr virus (EBV)-transformed lymphoblastoid cell lines |
| Q43483188 | Human DNA replication: fiber autoradiographic analysis of diploid cells from normal adults and from Fanconi's anemia and ataxia telangiectasia |
| Q24562757 | Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint |
| Q70497043 | Human chromosome 11 complements ataxia-telangiectasia cells but does not complement the defect in AT-like Chinese hamster cell mutants |
| Q37096936 | Human fibroblasts for large-scale "omics" investigations of ATM gene function |
| Q42551964 | Hypersensitivity of ataxia-telangiectasia fibroblasts to a nitric oxide donor |
| Q33619660 | Hypersensitivity to DNA-damaging agents in cultured cells from patients with Usher's syndrome and Duchenne muscular dystrophy |
| Q36561981 | ISG15 deregulates autophagy in genotoxin-treated ataxia telangiectasia cells |
| Q97519186 | Identification of Two Novel Mutations in the ATM Gene from Patients with Ataxia-Telangiectasia by Whole Exome Sequencing |
| Q44028462 | Identification of ataxia telangiectasia heterozygotes, a cancer prone population |
| Q40946661 | Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts |
| Q64387799 | Immunodeficiency, radiosensitivity, and the XCIND syndrome |
| Q34994580 | Immunological disorders and DNA repair |
| Q47621936 | In vitro radiosensitivity of primary human fibroblasts. Lack of correlation with acute radiation toxicity in patients with head and neck cancer |
| Q53184648 | In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy. |
| Q72693436 | Increased clastogenicity and decreased inhibition of DNA synthesis by neocarzinostatin and tallysomycin in ataxia telangiectasia lymphoid cells |
| Q38367382 | Increased radiosensitivity and the basic defect in ataxia telangiectasia |
| Q33894252 | Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency |
| Q40852425 | Increased sensitivity to chromatid aberration induction by bleomycin and neocarzinostatin results from alterations in a DNA damage response pathway |
| Q66704068 | Increased sensitivity to gamma irradiation of skin fibroblasts in Friedreich's ataxia |
| Q36861633 | Induced pluripotent stem cells from ataxia-telangiectasia recapitulate the cellular phenotype |
| Q40124888 | Induction of base damages representing a high risk site for double-strand DNA break formation in genomic DNA by exposure of cells to DNA damaging agents |
| Q24316119 | Induction of inositol 1,4,5 trisphosphate receptor genes by ionizing radiation |
| Q84586133 | Influence of environmental and genetic factors on variation in human response to DNA damaging agents |
| Q40762968 | Influence of interferon-gamma on radiation-induced apoptosis in normal and ataxia-telangiectasia fibroblast cell lines |
| Q37541006 | Inherently radioresistant cells exist in some human tumors |
| Q37122690 | Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer |
| Q44646967 | Inhibition of ATR kinase with the selective inhibitor VE-821 results in radiosensitization of cells of promyelocytic leukaemia (HL-60). |
| Q28239339 | Interaction between ATM protein and c-Abl in response to DNA damage |
| Q79124462 | Intrinsic susceptibility to radiation-induced apoptosis of human lymphocyte subpopulations |
| Q69939514 | Investigation of the cytotoxic effects of DNA damaging agents on neurofibromatosis cells |
| Q40075924 | Involvement of Poly (ADP-ribose) in the Radiation Response of Mammalian Cells |
| Q72468864 | Ionising radiation sensitivity in multiple sclerosis |
| Q38162722 | Ionizing radiation-induced responses in human cells with differing TP53 status |
| Q41811917 | Is chromatid-type damage in ataxia telangiectasia after irradiation at G0 a consequence of defective repair? |
| Q36300473 | Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype |
| Q40116737 | Karyotypic progression in human tumors |
| Q48812659 | Living history autobiography: clinical genetics: key to cancer etiology |
| Q28137625 | MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks |
| Q38766191 | Management of Cerebral Radiation Necrosis: A Retrospective Study of 12 Patients |
| Q37283218 | Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer |
| Q49099528 | Micronucleus induction by 60Co gamma-rays and fast neutrons in ataxia telangiectasia lymphocytes |
| Q37986682 | Molecular nature of radiation injury and DNA repair disorders associated with radiosensitivity. |
| Q36033084 | Motor pathway degeneration in young ataxia telangiectasia patients: A diffusion tractography study. |
| Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
| Q34395458 | Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia. |
| Q74355482 | Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest |
| Q59065543 | Neoplastic transformation induced by a direct perturbation of DNA |
| Q34037422 | New mutations in the ATM gene and clinical data of 25 AT patients |
| Q72468856 | Non-A, non-B hepatitis |
| Q37162103 | Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype |
| Q40215408 | Ocular manifestations of the neurocutaneous syndromes |
| Q40832206 | Oncogenic basis of radiation resistance. |
| Q33588436 | Osteosarcoma in a patient with Hutchinson-Gilford progeria |
| Q40521741 | Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant |
| Q33621450 | Parkinson's disease and Alzheimer's disease: hypersensitivity to X rays in cultured cell lines |
| Q27025786 | Pathogenesis of ataxia-telangiectasia: the next generation of ATM functions |
| Q57618664 | Patient-to-patient variability in the expression of radiation-induced normal tissue injury |
| Q45304998 | Perturbations of cell-cycle progression in γ-irradiated ataxia telangiectasia and Huntington's disease cells detected by DNA flow cytometric analysis |
| Q26749099 | Phenotypes and genotypes of the chromosomal instability syndromes |
| Q39414954 | Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer |
| Q24523941 | Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response |
| Q41506937 | Potential clinical impact of normal-tissue intrinsic radiosensitivity testing. |
| Q90319999 | Potential of serum microRNAs as biomarkers of radiation injury and tools for individualization of radiotherapy |
| Q38916634 | Prediction of radiation-induced toxicity by in vitro radiosensitivity of lymphocytes in prostate cancer patients |
| Q37417903 | Prevalence of ATM Sequence Variants in Northern Plains American Indian Cancer Patients. |
| Q34560071 | Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology |
| Q44403743 | Proceedings of The British Institute of Radiology Xeroradiography: some new applications October 16, 1975 |
| Q41001607 | Progress in radiotherapy |
| Q64390698 | Quantitation of the repair of gamma-radiation-induced double-strand DNA breaks in human fibroblasts |
| Q40821957 | Quantitative clinical radiobiology |
| Q42440648 | Quantitative replicon analysis of dna synthesis in cancer-prone conditions and the defects in bloom’s syndrome |
| Q33658791 | Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice |
| Q72897020 | Radiation Effects on Cultured Human Lymphoid Cells Analysis using the growth extrapolation method |
| Q89060421 | Radiation biology and oncology in the genomic era |
| Q30432746 | Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study |
| Q55038981 | Radiation oncology: a century of achievements. |
| Q38521237 | Radiation sensitivity and cancer in ataxia-telangiectasia |
| Q38484258 | Radiation-Induced Chromosome Aberrations in Ataxia Telangiectasia Cells: High Frequency of Deletions and Misrejoining Detected by FluorescenceIn SituHybridization |
| Q41065090 | Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: a closer look |
| Q26800196 | Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic |
| Q42482406 | Radiobiological studies in the naevoid basal cell carcinoma syndrome |
| Q38665620 | Radiogenomics and radiotherapy response modeling. |
| Q35135300 | Radiological imaging in ataxia telangiectasia: a review. |
| Q38523742 | Radioresistant DNA synthesis: an intrinsic feature of ataxia telangiectasia |
| Q47770267 | Radiosensitivity and oxidative signalling in ataxia telangiectasia: an update |
| Q36419108 | Radiosensitivity in ataxia-telangiectasia: a new explanation |
| Q77737374 | Radiosensitivity of normal tissues in ataxia-telangiectasia heterozygotes |
| Q26864434 | Radiosensitivity: evidence of an individual factor |
| Q50946282 | Rapid assay of intrinsic radiosensitivity based on apoptosis in human CD4 and CD8 T-lymphocytes. |
| Q28214575 | Recombinational DNA repair and human disease |
| Q59791546 | Reconstitution of the Ataxia-Telangiectasia Cellular Phenotype With Lentiviral Vectors |
| Q36002680 | Reduced DNA topoisomerase II activity in ataxia-telangiectasia cells |
| Q47376043 | Reduced DNA-dependent protein kinase activity in two cell lines derived from adult cancer patients with late radionecrosis |
| Q36797925 | Regulation of the cell cycle following DNA damage in normal and Ataxia telangiectasia cells |
| Q64388536 | Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase |
| Q28141152 | Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase |
| Q64390720 | Rejoining of DNA double‐strand breaks in human fibroblasts and its impairment in one ataxia telangiectasia and two fanconi strains |
| Q42125116 | Rejoining of double strand breaks in normal human and ataxia-telangiectasia fibroblasts after exposure to 60Co gamma-rays, 241Am alpha-particles or bleomycin |
| Q39382792 | Relation of D.N.A. repair processes to pathological ageing of the nervous system in xeroderma pigmentosum |
| Q42619834 | Relationship of cataract to radiation sensitivity |
| Q40930004 | Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase |
| Q39717161 | Repair deficient human disorders and cancer |
| Q39646472 | Repair of DNA damage induced by ionizing radiation and benzo[α]pyrene in mammalian cells |
| Q36203362 | Repair of ionizing radiation induced DNA damage In human lymphocytes |
| Q31031598 | Replication protein A is sequentially phosphorylated during meiosis |
| Q41502832 | Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions |
| Q36290269 | Response of sensitive human ataxia and resistant T-1 cell lines to accelerated heavy ions. |
| Q45304032 | Responses of huntington's disease and ataxia telangiectasia lymphoblastoid cells to bleomycin |
| Q55112653 | Role of Ionizing Radiation in Neurodegenerative Diseases. |
| Q36427460 | Sarcoma risk after radiation exposure |
| Q69620422 | Screening for interindividual differences in radiosensitivity by means of the micronucleus assay in human lymphocytes |
| Q43954989 | Self-treatment of cold sores with ice. |
| Q24309516 | Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage |
| Q33669532 | Sensitivity to ionising radiation of lymphocytes from Huntington's chorea patients compared to controls |
| Q40804276 | Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects |
| Q40527127 | Short term screening tests for carcinogens |
| Q33862705 | Signal Transduction and Cellular Responses to Ionizing Radiation |
| Q33192335 | Simultaneous measurement, using flow cytometry, of radiosensitivity and defective mitogen response in ataxia telangiectasia and related syndromes. |
| Q36179545 | Single strand breakage and repair in eukaryotic DNA as assayed by S1 nuclease |
| Q59064409 | Skin fibroblasts from a D-deletion type retinoblastoma patient are abnormally X-ray sensitive |
| Q40084829 | Some DNA-repair-deficient human syndromes and their implications for human health |
| Q42521072 | Some aspects of glutathione metabolism in ataxia-telangiectasia fibroblasts |
| Q66973383 | Specific cellular defects in patients with Fanconi anemia |
| Q63383725 | Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia |
| Q33670866 | Spontaneous and mutagen induced sister chromatid exchange in multiple sclerosis |
| Q36351344 | Spontaneous loss and alteration of antigen receptor expression in mature CD4+ T cells |
| Q35908249 | Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase |
| Q35570998 | Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells |
| Q52827047 | Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts. |
| Q37028705 | Studies of cellular hypersensitivity to ionising radiation in Friedreich's ataxia |
| Q37030751 | Studies of cellular radiosensitivity in hereditary disorders of nervous system and muscle |
| Q40638608 | Studies on the radiosensitivity of cells from patients with basal cell naevus syndrome. |
| Q41028783 | Superoxide dismutase and catalase activities in Ataxia telangiectasia and normal fibroblast cell extracts |
| Q44279949 | Survival of human diploid skin fibroblasts from normal individuals after X-irradiation |
| Q39172554 | Systemic effects of ionizing radiation at the proteome and metabolome levels in the blood of cancer patients treated with radiotherapy: the influence of inflammation and radiation toxicity |
| Q39034471 | T lymphocytes to predict radiation-induced late effects in normal tissues. |
| Q36840988 | The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast |
| Q38088935 | The ATM protein kinase: regulating the cellular response to genotoxic stress, and more |
| Q40715321 | The Oxygen Enhancement Ratio for Radiation Lethality in Ataxia Telangiectasia Cells |
| Q39595329 | The arrangement of immunoglobulin and T cell receptor genes in human lymphoproliferative disorders. |
| Q24304499 | The ataxia-oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4 |
| Q40372170 | The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer |
| Q34379020 | The breakpoint of an inversion of chromosome 14 in a T-cell leukemia: sequences downstream of the immunoglobulin heavy chain locus are implicated in tumorigenesis |
| Q40386992 | The controlling role of ATM in homologous recombinational repair of DNA damage |
| Q40141698 | The current state of research with peripheral tissues in Huntington disease |
| Q72662748 | The effect of bleomycin on DNA synthesis in ataxia telangiectasia lymphoid cells |
| Q40873279 | The gene as theme in the paradigm of cancer |
| Q34061457 | The human LINE-1 retrotransposon creates DNA double-strand breaks. |
| Q37606136 | The human intra-S checkpoint response to UVC-induced DNA damage |
| Q35202474 | The identification of fanconi anemia genotypes by clastogenic stress |
| Q41514196 | The induction of gamma-endonuclease-susceptible sites by γ-rays in cho cells and their cellular repair are not affected by the presence of thiol compounds during irradiation |
| Q39469689 | The molecular genetics of the incision step in the DNA excision repair process |
| Q24685932 | The molecular pathology of primary immunodeficiencies |
| Q40580160 | The nature of ataxia-telangiectasia: problems and perspectives |
| Q34195541 | The pathogenesis of ataxia-telangiectasia. Learning from a Rosetta Stone |
| Q37603650 | The proteasome activator PA200 regulates tumor cell responsiveness to glutamine and resistance to ionizing radiation. |
| Q41021472 | The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks. |
| Q40525439 | The rejoining of double-strand breaks in DNA by human cell extracts |
| Q53615579 | The relative biological effectiveness of densely ionizing heavy-ion radiation for inducing ocular cataracts in wild type versus mice heterozygous for the ATM gene. |
| Q53722671 | The repair of potentially lethal damage in x-irradiated cultures of normal and ataxia telangiectasia human fibroblasts. |
| Q39551828 | The response of ataxia telangiectasia cells to bleomycin |
| Q45304270 | The response of cells from patients with Huntington's chorea to mutagen-induced chromosome damage |
| Q43602331 | The response of normal and ataxia-telangiectasia human fibroblasts to the lethal effects of far, mid and near ultraviolet radiations |
| Q38598900 | The role of repair in radiobiology |
| Q36267279 | The spectrum of ATM missense variants and their contribution to contralateral breast cancer |
| Q42857103 | The use of recombinant DNA plasmids for the determination of DNA-repair and recombination in cultured mammalian cells. |
| Q40905943 | Theory and practice of predictive assays in radiation therapy |
| Q59198405 | Therapeutic targets and investigated treatments for Ataxia-Telangiectasia |
| Q33489522 | Thrombocytopenia with absent radii (TAR) syndrome: a new increased cellular radiosensitivity syndrome |
| Q40790692 | Transcriptional downregulation of ATM by EGF is defective in ataxia-telangiectasia cells expressing mutant protein. |
| Q48710739 | Unfinished business: an essay on finally leaving the bench |
| Q44200828 | Unusual levels of (ADP-ribose)n and DNA synthesis in ataxia telangiectasia cells following gamma-ray irradiation |
| Q52548762 | Upregulation of FasL and apoptosis in thymic lymphomas in Atm knock-in mice. |
| Q38227296 | Uracil-DNA glycosylases and DNA uracil repair |
| Q72018295 | Use of Fluorescencein SituHybridization to Determine the Relationship between Chromosome Aberrations and Cell Survival in Eight Human Fibroblast Strains |
| Q59139067 | Use of Low-dose Rate Irradiation to Measure the Intrinsic Radiosensitivity of Human T-lymphocytes |
| Q59139064 | Use of an Internal Standard in Comparative Measurements of the Intrinsic Radiosensitivities of Human T-lymphocytes |
| Q37486208 | Use of cytokine therapy in primary immunodeficiency |
| Q69870456 | Use of rapid tests of cellular radiosensitivity in radiotherapeutic practice |
| Q98781888 | Use of the cell division assay to diagnose Fanconi anemia patients' hypersensitivity to mitomycin C |
| Q40519651 | V(D)J recombination and double-strand break repair |
| Q48829986 | Validation of a flow cytometry-based detection of γ-H2AX, to measure DNA damage for clinical applications. |
| Q40710240 | Weiss Lecture. Effects of radiations of different qualities on cells: molecular mechanisms of damage and repair |
| Q55474923 | Wortmannin sensitizes human glioblastoma cell lines carrying mutant and wild type TP53 gene to radiation. |
| Q89688838 | Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, induces accumulation of DNA double-strand breaks |
| Q40796094 | X-irradiation induces up-regulation of ATM gene expression in wild-type lymphoblastoid cell lines, but not in their heterozygous or homozygous ataxia-telangiectasia counterparts |
| Q35065706 | X-ray radiation and the risk of multiple sclerosis: Do the site and dose of exposure matter? |
| Q34250062 | X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents |
| Q73812894 | [Genetic predisposition and radiation sensitivity of tumors] |
| Q36638226 | p53 centrosomal localization diagnoses ataxia-telangiectasia homozygotes and heterozygotes |
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