Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells

scientific article published on August 2004

Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.78.15.8047-8058.2004
P932PMC publication ID446122
P698PubMed publication ID15254176
P5875ResearchGate publication ID8455707

P2093author name stringRonald G Crystal
Ralf F Pettersson
Philip L Leopold
Theresa Vincent
P2860cites workCutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cellsQ22010225
Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sortingQ24291163
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junctionQ24291966
Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escapeQ24307684
HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackievirusesQ24312224
Fatty acid modification of the coxsackievirus and adenovirus receptorQ24537668
Receptor for the group B coxsackieviruses and adenoviruses: CARQ28210093
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5Q28303765
The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brainQ28584739
Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachmentQ29615852
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteriaQ29616614
Adhesion molecules and gene transferQ30958956
The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).Q33289422
Adenovirus internalization and infection require dynaminQ33783549
Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.Q33815931
Evolution of cell recognition by virusesQ34250512
NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.Q34720640
Cell physiology as a variable in gene transfer to endotheliumQ35095397
The p38 mitogen-activated protein kinase pathway and its role in interferon signalingQ35119367
Measurement of in vivo rectal mucosal cytokine and eicosanoid production in ulcerative colitis using filter paperQ35359745
The coxsackie-adenovirus receptor--a new receptor in the immunoglobulin family involved in cell adhesion.Q35607448
Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-alpha plus interferon-gamma Does not reduce leukocyte transmigratiQ35747154
Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayersQ35835763
Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization.Q36234671
Cytokines and endothelial cell biologyQ36565690
Mutations that alter an Arg-Gly-Asp (RGD) sequence in the adenovirus type 2 penton base protein abolish its cell-rounding activity and delay virus reproduction in flat cellsQ36651749
Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infectionQ37371791
Coxsackievirus and adenovirus receptor cytoplasmic and transmembrane domains are not essential for coxsackievirus and adenovirus infection.Q39552063
Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transferQ39582545
Expression of the coxsackievirus and adenovirus receptor in cultured human umbilical vein endothelial cells: regulation in response to cell densityQ39595626
Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapyQ39876759
Leukocyte-endothelial adhesion moleculesQ40392834
Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.Q40402637
Endothelial-leukocyte adhesion moleculesQ40898249
Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptorQ40971242
Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cellsQ41057879
Quantitation of cytokine levels in skin graft donor site wound fluidQ41066769
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epitheliumQ41644008
Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivoQ41894646
High bronchoalveolar levels of tumor necrosis factor and its inhibitors, interleukin-1, interferon, and elastase, in patients with adult respiratory distress syndrome after trauma, shock, or sepsisQ41909605
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferonQ42511354
Vascular endothelial platelet endothelial adhesion molecule-1 (PECAM-1) expression is decreased by TNF-alpha and IFN-gamma. Evidence for cytokine-induced destabilization of messenger ribonucleic acid transcripts in bovine endothelial cells.Q42513902
Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.Q42520814
Variation in adenovirus receptor expression and adenovirus vector-mediated transgene expression at defined stages of the cell cycleQ43687076
Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liverQ43884266
CAR is a cell-cell adhesion protein in human cancer cells and is expressionally modulated by dexamethasone, TNFalpha, and TGFbetaQ44155131
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.Q45858661
Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectinQ45862541
Modulation of gene expression after replication-deficient, recombinant adenovirus-mediated gene transfer by the product of a second adenovirus vector.Q45868852
Stimulatory and inhibitory action of cytokines on the regulation of hCMV-IE promoter activity in human endothelial cellsQ45869823
Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cellsQ48000569
Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epitheliaQ50109548
Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serumQ70399995
Inhibition of platelet endothelial cell adhesion molecule-1 synthesis and leukocyte transmigration in endothelial cells by the combined action of TNF-alpha and IFN-gammaQ71397441
Prolonged cytokine exposure causes a dynamic redistribution of endothelial cell adhesion molecules to intercellular junctionsQ71692853
IFN-gamma and TNF-alpha induce redistribution of PECAM-1 (CD31) on human endothelial cellsQ72260770
Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 alpha/beta, tumor necrosis factor-alpha and interferon-gammaQ72802695
The tumour necrosis factor-alpha induced vascular permeability is associated with a reduction of VE-cadherin expressionQ74097443
Levels of tumor necrosis factor-alpha (TNF-alpha) and soluble TNF receptors in chronic venous leg ulcers--correlations to healing statusQ74323419
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
AdenoviridaeQ193447
CoxsackievirusQ1138287
P304page(s)8047-8058
P577publication date2004-08-01
P1433published inJournal of VirologyQ1251128
P1476titleCytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cells
P478volume78

Reverse relations

cites work (P2860)
Q36419822Adenoviral vectors--how to use them in cancer gene therapy?
Q57016612Autoimmunity in Coxsackievirus B3 induced myocarditis: role of estrogen in suppressing autoimmunity
Q50032046CAR: A key regulator of adhesion and inflammation
Q91979893CEACAM-1 promotes myocardial injury following coxsackievirus infection by regulating the coxsackievirus-adenovirus receptor
Q36171460Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface
Q46247896Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro
Q36216936Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
Q40540158Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.
Q28505322Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testis
Q91496381Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress
Q37583568Cytokine determinants of viral tropism.
Q55499725Development of a Serum-free Suspension Process for the Production of a Conditionally Replicating Adenovirus using A549 Cells.
Q39594713E-selectin is a viable route of infection for polymer-coated adenovirus retargeting in TNF-α-activated human umbilical vein endothelial cells
Q41979690Ephrin-B2 expression critically influences Nipah virus infection independent of its cytoplasmic tail
Q35139196Fiber and penton base capsid modifications yield diminished adenovirus type 5 transduction and proinflammatory gene expression with retention of antigen-specific humoral immunity
Q33879907Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis.
Q36681507Influence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35.
Q45287872Interferon-gamma and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells
Q38199343JAM-related proteins in mucosal homeostasis and inflammation
Q33933004Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene
Q38751678Regulation of the Coxsackie and adenovirus receptor expression is dependent on cystic fibrosis transmembrane regulator in airway epithelial cells
Q92135701Secondary Placental Defects in Cxadr Mutant Mice
Q34765825Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins
Q40385648Targeting viral-mediated transduction to the lung airway epithelium with the anti-inflammatory cationic lipid dexamethasone-spermine.
Q40303730The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis
Q36831671The role of junctional adhesion molecules in vascular inflammation
Q36955901Therapeutic potential of replication-selective oncolytic adenoviruses on cells from familial and sporadic desmoid tumors
Q40208347What is CAR doing in the middle of the adult neurogenic road?

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