The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis

scientific article published on 15 March 2006

The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2006.01.025
P8608Fatcat IDrelease_zpw3mybs4ndsfpb5knm52ueoqu
P698PubMed publication ID16542650

P50authorLennart PhilipsonQ6048280
Jonas FuxeQ54250889
P2093author name stringRalf F Pettersson
Johan Thyberg
Sven Pettersson
Elisabeth Raschperger
P2860cites workCTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebratesQ22008576
Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sortingQ24291163
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junctionQ24291966
Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophilsQ24299261
A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growthQ24301014
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junctionQ24303832
Blood clearance rates of adenovirus type 5 in miceQ45871684
CTX, a novel molecule specifically expressed on the surface of cortical thymocytes in Xenopus.Q48065352
CLMP, a novel member of the CTX family and a new component of epithelial tight junctionsQ48222946
Structure and chromosomal localization of the murine coxsackievirus and adenovirus receptor geneQ50102512
Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditisQ50108244
Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epitheliaQ50109548
Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escapeQ24307684
HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackievirusesQ24312224
Isoform-specific expression of the Coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discsQ24313029
The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamilyQ24316074
Expression of the adenovirus receptor and its interaction with the fiber knobQ28144371
A transmembrane tight junction protein selectively expressed on endothelial cells and plateletsQ28201696
The JAM family of junctional adhesion moleculesQ28205895
Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cellsQ28208656
Tight junction proteinsQ28217124
Coxsackievirus and adenovirus receptor is essential for cardiomyocyte developmentQ28247971
Coxsackievirus-adenovirus receptor (CAR) is essential for early embryonic cardiac developmentQ28265595
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondriaQ28285347
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5Q28303765
Molecular cloning of a novel immunoglobulin superfamily gene preferentially expressed by brain and testisQ28506184
Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesityQ28568508
The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brainQ28584739
Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-CQ28589240
The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2)Q28592551
The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).Q33289422
CAR: a virus receptor within the tight junctionQ33986342
The JAM family of proteinsQ34650444
A new look at viruses in type 1 diabetes.Q35068487
Molecular perspective on tight-junction assembly and epithelial polarityQ36093742
A mouse model for adenovirus gene deliveryQ36529815
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient miceQ37486598
Junctional complexes and cell polarity in the urinary tubuleQ39545895
Targeting of a short peptide derived from the cytoplasmic tail of the G1 membrane glycoprotein of Uukuniemi virus (Bunyaviridae) to the Golgi complexQ39582889
Apical localization of the coxsackie-adenovirus receptor by glycosyl-phosphatidylinositol modification is sufficient for adenovirus-mediated gene transfer through the apical surface of human airway epitheliaQ39606560
BT-IgSF, a novel immunoglobulin superfamily protein, functions as a cell adhesion moleculeQ40441831
Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectorsQ40815226
Expression of the primary coxsackie and adenovirus receptor is downregulated during skeletal muscle maturation and limits the efficacy of adenovirus-mediated gene delivery to muscle cellsQ40957513
Cytokine-mediated downregulation of coxsackievirus-adenovirus receptor in endothelial cellsQ41039128
Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivoQ44486162
Efficient gene transfer into retinal cells using adenoviral vectors: dependence on receptor expressionQ44909595
Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous systemQ45723474
Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus- and adenovirus-mediated intracerebral gene transfer in vivoQ45856841
Expression of the coxsackie and adenovirus receptor in human astrocytic tumors and xenograftsQ45857617
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectAdenoviridaeQ193447
tissue homeostasisQ14873636
P304page(s)1566-1580
P577publication date2006-03-15
P1433published inExperimental Cell ResearchQ1524289
P1476titleThe coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis
P478volume312

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cites work (P2860)
Q21129349"You Shall Not Pass"-tight junctions of the blood brain barrier
Q643778661. Alternative splicing of viral receptors: A review of the diverse morphologies and physiologies of adenoviral receptors
Q37162704A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition
Q33994011Adenovirus receptors and their implications in gene delivery
Q38723135Adenovirus transduction: More complicated than receptor expression
Q34701038Adrenal gland infection by serotype 5 adenovirus requires coagulation factors
Q39238492Anti-coxsackievirus B4 (CV-B4) enhancing activity of serum associated with increased viral load and pathology in mice reinfected with CV-B4.
Q37027899Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis
Q64102673Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology
Q33995638CAR modulates E-cadherin dynamics in the presence of adenovirus type 5.
Q37420781CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter
Q35880139Cell adhesion molecules in chemically-induced renal injury
Q36645364Cell-cell adhesion in lung endothelium
Q64063299Cisplatin Synergistically Enhances Antitumor Potency of Conditionally Replicating Adenovirus via p53 Dependent or Independent Pathways in Human Lung Carcinoma
Q35029152Connections matter--how viruses use cell–cell adhesion components
Q39837761Coxsackie adenovirus receptor (CAR) regulates integrin function through activation of p44/42 MAPK.
Q36171460Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface
Q46247896Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro
Q36216936Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes
Q38435764Coxsackievirus and adenovirus receptor expression in non-malignant lung tissues and clinical lung cancers
Q33841456Cross-talk between tight and anchoring junctions-lesson from the testis
Q64075738Data on localization of coxsackievirus and adenovirus receptor (CAR) in prenatal and adult rat olfactory, intestine, pancreas, liver, ovary, and testis
Q92356999Data on localization of coxsackievirus and adenovirus receptor (CAR) in the embryonic rat brain
Q47408707Defenders and Challengers of Endothelial Barrier Function
Q37278421Diabetic albuminuria is due to a small fraction of nephrons distinguished by albumin-stained tubules and glomerular adhesions.
Q43915607Differential expression of coxsackievirus and adenovirus receptor on alveolar epithelial cells between fetal and adult mice determines their different susceptibility to coxsackievirus B infection
Q50061615Down-regulation of coxsakie and adenovirus receptor during embryo implantation
Q39826803Downregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1alpha.
Q41947416Enhanced Gene Delivery to Human Primary Endothelial Cells Using Tropism-Modified Adenovirus Vectors
Q38403637Epithelial adhesion molecules and the regulation of intestinal homeostasis during neutrophil transepithelial migration
Q21134565Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice
Q52600112Evaluation of adenovirus 19a as a novel vector for mucosal vaccination against influenza A viruses.
Q44106635Expression and function of the coxsackie and adenovirus receptor in Barrett's esophagus and associated neoplasia
Q28590625Expression of coxsackievirus and adenovirus receptor isoforms in developing mouse bladder uroepithelium
Q35641009Expression of human decay-accelerating factor on intestinal epithelium of transgenic mice does not facilitate infection by the enteral route
Q33674054Extracellular matrix and its role in spermatogenesis
Q37954393Gene expression profile of lymphatic endothelial cells
Q37967602Genetic approaches to study glial cells in the rodent brain.
Q88622719Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells
Q30660209Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease
Q42935421Hepatic tight junctions: from viral entry to cancer metastasis
Q24613509Homeostasis and inflammation in the intestine
Q36968335Human enterovirus species B in ileocecal Crohn's disease
Q37116929Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.
Q54360931Hypertonic stress promotes the upregulation and phosphorylation of zonula occludens 1.
Q33317834Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.
Q35006897Impact of the coxsackievirus and adenovirus receptor on the adenoma-carcinoma sequence of colon cancer
Q28513161Interaction of the Coxsackie and adenovirus receptor (CAR) with the cytoskeleton: binding to actin
Q39208267Interspecies differences in virus uptake versus cardiac function of the coxsackievirus and adenovirus receptor
Q24305441Isoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epithelia
Q38199343JAM-related proteins in mucosal homeostasis and inflammation
Q48139196KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation.
Q37081112Loss of the coxsackie and adenovirus receptor contributes to gastric cancer progression
Q33933004Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene
Q39016237Neutrophil-derived JAML inhibits repair of intestinal epithelial injury during acute inflammation.
Q39571698Novel splice variant CAR 4/6 of the coxsackie adenovirus receptor is differentially expressed in cervical carcinogenesis
Q34163593Pregnancy loss following coxsackievirus b3 infection in mice during early gestation due to high expression of coxsackievirus-adenovirus receptor (CAR) in uterus and embryo
Q37214268Presence of the coxsackievirus and adenovirus receptor (CAR) in human neoplasms: a multitumour array analysis
Q58792876Protective Role of Coxsackie-Adenovirus Receptor in the Pathogenesis of Inflammatory Bowel Diseases
Q38751678Regulation of the Coxsackie and adenovirus receptor expression is dependent on cystic fibrosis transmembrane regulator in airway epithelial cells
Q36312788Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor
Q33869656Secretion and organization of a cornea-like tissue in vitro by stem cells from human corneal stroma
Q33559484Sertoli-germ cell junctions in the testis: a review of recent data
Q43253468Sodium butyrate increases expression of the coxsackie and adenovirus receptor in colon cancer cells
Q50091770Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor.
Q39824366Suppression of ovarian cancer growth via systemic administration with liposome-encapsulated adenovirus-encoding endostatin
Q36799390Systemically administered liposome-encapsulated Ad-PEDF potentiates the anti-cancer effects in mouse lung metastasis melanoma
Q41927259TNFalpha shedding and epidermal inflammation are controlled by Jun proteins
Q36914535TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.
Q40185489The Coxsackie and adenovirus receptor binds microtubules and plays a role in cell migration
Q34981717The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
Q28088573The Mammalian Blood-Testis Barrier: Its Biology and Regulation
Q47074232The coxsackie and adenovirus receptor (CAR) is required for renal epithelial differentiation within the zebrafish pronephros
Q38223244The role of epithelial tight junctions involved in pathogen infections
Q37733955Tight junctions in the testis: new perspectives.
Q37420725Tight junctions: a barrier to the initiation and progression of breast cancer?
Q40819406Tropism Analysis of Two Coxsackie B5 Strains Reveals Virus Growth in Human Primary Pancreatic Islets but not in Exocrine Cell Clusters In Vitro
Q35568762Two types of functionally distinct fiber containing structural protein complexes are produced during infection of adenovirus serotype 5
Q57920489Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells
Q38929867miR-466 is putative negative regulator of Coxsackie virus and Adenovirus Receptor

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