Cell-cell adhesion in lung endothelium

scientific article published on 3 November 2006

Cell-cell adhesion in lung endothelium is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPLUNG.00386.2006
P698PubMed publication ID17085518
P5875ResearchGate publication ID6710657

P2093author name stringD Michael Shasby
P2860cites workHakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complexQ24292279
Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinityQ24295448
Segregation of receptor and ligand regulates activation of epithelial growth factor receptorQ24298164
The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1Q24299978
Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148Q24303092
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4Q24336334
VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of TiamQ24515256
Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cellsQ24515257
VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contactsQ24534512
p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin InteractionQ24551143
Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.Q24608988
Deconstructing the cadherin-catenin-actin complexQ24609677
A novel endothelial-specific membrane protein is a marker of cell-cell contactsQ24642987
DNAM-1 and PVR regulate monocyte migration through endothelial junctionsQ24647699
A novel role for p120 catenin in E-cadherin functionQ24674430
A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptideQ41498808
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblastsQ42796669
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filamentsQ42861316
Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.Q42915675
Regulation of beta-catenin structure and activity by tyrosine phosphorylation.Q43560193
Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylationQ43688548
Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesionQ44164981
Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strainsQ44239722
Targeted disruption of endothelial cell-selective adhesion molecule inhibits angiogenic processes in vitro and in vivoQ44486162
NADPH oxidase mediates vascular endothelial cadherin phosphorylation and endothelial dysfunctionQ44991524
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.Q45124238
Critical roles of CD146 in zebrafish vascular developmentQ45174391
MAPKs (ERK1/2, p38) and AKT can be phosphorylated by shear stress independently of platelet endothelial cell adhesion molecule-1 (CD31) in vascular endothelial cellsQ45236650
Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye.Q45537733
Pathophysiological consequences of VEGF-induced vascular permeabilityQ46349878
G alpha12 interaction with alphaSNAP induces VE-cadherin localization at endothelial junctions and regulates barrier functionQ46568458
Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammationQ46811079
Vasculogenesis, angiogenesis, and growth factors: ephrins enter the fray at the borderQ47964362
Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formationQ47996855
Loss of PECAM-1 function impairs alveolarization.Q51298778
Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin.Q52120808
Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.Q52537297
Identification of CD146 as a component of the endothelial junction involved in the control of cell-cell cohesion.Q52544714
Cdc42 regulates the restoration of endothelial barrier function.Q52552672
Rho1 regulates Drosophila adherens junctions independently of p120ctn.Q52661448
PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists.Q53621863
Effects of calcium on transendothelial albumin transfer and electrical resistance.Q54438005
Transference of recombinant VE-cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability.Q54513750
Cell-cell interactions in early embryogenesis: a molecular approach to the role of calcium.Q54529110
Importance of Junctional Adhesion Molecule-A for Neointimal Lesion Formation and Infiltration in Atherosclerosis-Prone MiceQ57574599
Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNAQ59064208
The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragilityQ24675378
Receptor protein tyrosine phosphatase micro regulates the paracellular pathway in human lung microvascular endotheliaQ24675717
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludinQ24682664
Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cellsQ24682677
The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctnQ24683225
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesionQ24683255
p120(ctn) acts as an inhibitory regulator of cadherin function in colon carcinoma cellsQ24684160
A new crystal structure, Ca2+ dependence and mutational analysis reveal molecular details of E-cadherin homoassociationQ27617935
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-cateninQ27631714
Untangling Desmosomal Knots with Electron TomographyQ27642269
p120(ctn) binds to the membrane-proximal region of the E-cadherin cytoplasmic domain and is involved in modulation of adhesion activityQ28139957
Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesisQ28140788
Cdc42 and Rac1 regulate the interaction of IQGAP1 with beta-cateninQ28143737
SHP2 association with VE-cadherin complexes in human endothelial cells is regulated by thrombinQ28145139
Role of claudin interactions in airway tight junctional permeabilityQ28156383
Size-selective loosening of the blood-brain barrier in claudin-5-deficient miceQ28203769
PECAM-1: old friend, new partnersQ28205886
The JAM family of junctional adhesion moleculesQ28205895
Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cellsQ28208656
Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cellsQ28216010
ROCK and Dia have opposing effects on adherens junctions downstream of RhoQ28216591
Histamine stimulates phosphorylation of adherens junction proteins and alters their link to vimentinQ28217128
High-throughput mapping of a dynamic signaling network in mammalian cellsQ28239249
IQGAP1: a key regulator of adhesion and migrationQ28250427
The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactionsQ28268648
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesionQ28278750
Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heartQ28293128
Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherinQ28294723
VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassemblyQ28298669
N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesisQ28505270
Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary glandQ28508350
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular developmentQ28508534
A monoclonal antibody disrupting calcium-dependent cell-cell adhesion of brain tissues: possible role of its target antigen in animal pattern formationQ37686036
Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytesQ38489431
Hyperosmolarity enhances the lung capillary barrierQ40156527
Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transductionQ40251249
Spatial control of actin organization at adherens junctions by a synaptotagmin-like protein BtszQ40252264
Loss of proline-rich tyrosine kinase 2 function induces spreading and motility of epithelial prostate cells.Q40265863
The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasisQ40303730
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.Q40535764
Histamine selectively interrupts VE-cadherin adhesion independently of capacitive calcium entryQ40541215
Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.Q40641504
Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarctionQ40643967
Melanoma progression-associated glycoprotein MUC18/MCAM mediates homotypic cell adhesion through interaction with a heterophilic ligandQ41076891
Polarized monolayers formed by epithelial cells on a permeable and translucent supportQ41233493
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesionQ28587829
Association of Csk to VE-cadherin and inhibition of cell proliferationQ28591299
The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnoverQ28910197
Calcium site mutations in cadherin: impact on adhesion and evidence of cooperativity.Q30354650
Junctional adhesion molecule-A-deficient polymorphonuclear cells show reduced diapedesis in peritonitis and heart ischemia-reperfusion injury.Q30476048
Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras.Q30477010
Outside-in signaling pathway linked to CD146 engagement in human endothelial cellsQ33921887
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherinQ34099519
Claudins create charge-selective channels in the paracellular pathway between epithelial cellsQ34132571
Nectin and afadin: novel organizers of intercellular junctions.Q34161446
Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.Q34220056
Turn-off, drop-out: functional state switching of cadherinsQ34621022
A cell surface molecule involved in aggregation of embryonic liver cellsQ34713985
Complex phenotype of mice lacking occludin, a component of tight junction strands.Q34781594
Cadherins as Modulators of Cellular PhenotypeQ35564806
Junctional adhesion molecules (JAMs): more molecules with dual functions?Q35600846
E-cadherin null mutant embryos fail to form a trophectoderm epitheliumQ35691712
Endothelial cell-cell junctions: happy togetherQ35741007
The cross-Rho'ds of cell-cell adhesionQ35767359
The tight junction: a multifunctional complexQ35777543
Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasisQ35842988
Protecting your tail: regulation of cadherin degradation by p120-cateninQ35885630
Vascular remodeling in the circulations of the lungQ35913844
The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-cateninQ36229078
The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin)Q36235299
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cellsQ36316586
Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?Q36325631
Identification of a Ca2(+)-dependent cell-cell adhesion molecule in endothelial cellsQ36383366
Claudins and epithelial paracellular transportQ36387912
Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivoQ36435638
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.Q36834868
Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptideQ36847632
Antibodies to liver cell adhesion molecule perturb inductive interactions and alter feather pattern and structureQ37405712
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient miceQ37486598
P433issue3
P921main subjectendotheliumQ111140
cell adhesionQ187640
P304page(s)L593-607
P577publication date2006-11-03
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titleCell-cell adhesion in lung endothelium
P478volume292