A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide

scientific article published on February 1986

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide is …
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scholarly articleQ13442814

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P356DOI10.1083/JCB.102.2.457
P932PMC publication ID2114088
P698PubMed publication ID3511070
P5875ResearchGate publication ID19650991

P50authorKai SimonsQ880181
P2093author name stringGumbiner B
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Cell surface polarity in epithelia.Q34195966
Experimental modulation of occluding junctions in a cultured transporting epitheliumQ36202025
Occluding junctions and cytoskeletal components in a cultured transporting epitheliumQ36202080
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Twenty-first Bowditch lecture. The epithelial junction: bridge, gate, and fenceQ36320057
Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cellsQ36398123
Structure of tight junctions in epithelia with different permeabilityQ37460393
Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cellsQ37604054
Anomalous interaction of the acetylcholine receptor protein with the nonionic detergent Triton X-114Q37677551
Isolation of a cDNA clone for the liver cell adhesion molecule (L-CAM).Q37686111
Redistribution of surface macromolecules in dissociated epithelial cellsQ39408257
Modulation of Cell Adhesion during Induction, Histogenesis, and Perinatal Development of the Nervous SystemQ40109682
EFFECTS OF CALCIUM DEPLETION ON THE JUNCTIONAL COMPLEX BETWEEN OXYNTIC CELLS OF GASTRIC GLANDSQ41060743
A technique for ultracryotomy of cell suspensions and tissuesQ41169027
Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugsQ41238934
A monoclonal antibody against a 135-K Golgi membrane protein.Q41321939
Different modes of internalization of proteins associated with adhaerens junctions and desmosomes: experimental separation of lateral contacts induces endocytosis of desmosomal plaque materialQ41323428
Structural integrity of hepatocyte tight junctionsQ41403595
Infectious entry pathway of influenza virus in a canine kidney cell lineQ41439180
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cellsQ41468891
Vesicular stomatitis virus infects and matures only through the basolateral surface of the polarized epithelial cell line, MDCK.Q41527546
Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationshipsQ41577366
Development of cell surface polarity in the epithelial Madin-Darby canine kidney (MDCK) cell line.Q41584376
Identification of two strains of MDCK cells which resemble separate nephron tubule segmentsQ42445987
Ontogenetic expression of cell adhesion molecules: L-CAM is found in epithelia derived from the three primary germ layersQ42455341
Identification of desmosomal surface components (desmocollins) and inhibition of desmosome formation by specific Fab'.Q42456021
Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula OccludensQ43798217
Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissueQ44798802
Cell-cell interactions in early embryogenesis: a molecular approach to the role of calcium.Q54529110
Cell-cell interaction and polarity of epithelial cells: specific perturbation using a monoclonal antibody.Q55062706
Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylationQ57960257
A specific glycoprotein as the target site of adhesion blocking Fab in aggregating Dictyostelium cellsQ67015884
A simple method for producing antibody specific to a single selected diffusible antigenQ70070094
Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamineQ70669685
Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibodyQ71259159
Preparation of Fab fragments from IgGs of different animal speciesQ71518920
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages12
P304page(s)457-468
P577publication date1986-02-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleA functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide
P478volume102

Reverse relations

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Q77983578Organ preservation solutions increase endothelial permeability and promote loss of junctional proteins
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Q35650728PALS1 regulates E-cadherin trafficking in mammalian epithelial cells
Q34886029PAR1b promotes cell-cell adhesion and inhibits dishevelled-mediated transformation of Madin-Darby canine kidney cells
Q33618346PLEKHA7 modulates epithelial tight junction barrier function
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Q28577856Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia
Q41456379Permeabilization of MDCK cells with cholesterol binding agents: dependence on substratum and confluency
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Q73718379Phorbol ester induced changes in tight and adherens junctions in the choroid plexus epithelium and in the ependyma
Q21296710Plakoglobin: role in tumorigenesis and metastasis
Q22009075Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions
Q41631117Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells
Q35694152Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane
Q30439491RNA interference techniques to study epithelial cell adhesion and polarity
Q28250836RalA and RalB differentially regulate development of epithelial tight junctions
Q54379074Regeneration of resistance and ion transport in rabbit corneal epithelium after induced surface cell exfoliation.
Q30445851Regulated synthesis and functions of laminin 5 in polarized madin-darby canine kidney epithelial cells
Q40642345Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions.
Q47370933Regulation of Kv1.4 potassium channels by PKC and AMPK kinases
Q36529642Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane
Q35612267Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
Q33306608Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2
Q42229415Regulation of tight junction assembly and epithelial polarity by a resident protein of apical endosomes
Q39602751Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.
Q38288755Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line.
Q34690508Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells
Q73409282Role of cadherins 5 and 13 in the aortic endothelial barrier
Q40700929Role of nectin in organization of tight junctions in epithelial cells
Q93086454SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility
Q41028549SNAP-23 requirement for transferrin recycling in Streptolysin-O-permeabilized Madin-Darby canine kidney cells
Q40826309SNARE protein trafficking in polarized MDCK cells
Q36828527Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions
Q36221176Selective anchoring in the specific plasma membrane domain: a role in epithelial cell polarity
Q34618292Sequence analysis of a cDNA clone encoding the liver cell adhesion molecule, L-CAM.
Q35073616Sertoli cell tight junction dynamics: their regulation during spermatogenesis
Q34180670Signalling to and from tight junctions
Q33655249Structure of the gene for the liver cell adhesion molecule, L-CAM
Q40224183Study of claudin function by RNA interference
Q41579925Surface binding and uptake of cadmium (Cd2+) by LLC-PK1 cells on permeable membrane supports
Q27310572Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation
Q34692456Syntaxin 16 regulates lumen formation during epithelial morphogenesis.
Q27680792TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration
Q36531120Temporal changes in the expression and distribution of adhesion molecules during liver development and regeneration
Q47724366Testin secreted by Sertoli cells is associated with the cell surface, and its expression correlates with the disruption of Sertoli-germ cell junctions but not the inter-Sertoli tight junction
Q35545759The Bacteroides fragilis toxin fragilysin disrupts the paracellular barrier of epithelial cells
Q33290801The E-cadherin promoter: functional analysis of a G.C-rich region and an epithelial cell-specific palindromic regulatory element
Q37824021The LKB1/AMPK polarity pathway
Q35944103The Staphylococcus aureus alpha-toxin perturbs the barrier function in Caco-2 epithelial cell monolayers by altering junctional integrity
Q33616743The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
Q37064013The blood-brain barrier in and out of cell culture
Q39758028The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.
Q39473606The cell biology of the nerve terminal
Q24567493The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species
Q36216831The effect of neutrophil migration on epithelial permeability
Q41523151The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions
Q39546381The epithelial tight junction: structure, function and preliminary biochemical characterization
Q36315068The formation of viroplasm-like structures by the rotavirus NSP5 protein is calcium regulated and directed by a C-terminal helical domain
Q42570947The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells
Q39947404The interaction of Streptococcus pneumoniae with plasmin mediates transmigration across endothelial and epithelial monolayers by intercellular junction cleavage
Q40903764The molecular organization of tight junctions
Q41272296The protein kinase C activator TPA modulates cellular levels and distribution of E‐cadherin in HT‐29 human intestinal epithelial cells
Q82263885The role of EFA6, exchange factor for Arf6, for tight junction assembly, functions, and interaction with the actin cytoskeleton
Q47797420The role of cadherin endocytosis in endothelial barrier regulation: involvement of protein kinase C and actin-cadherin interactions
Q40877521The role of cell adhesion molecules in cancer invasion and metastasis
Q28289033The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex
Q30431153The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell-ECM signaling
Q30654463The spatial organization of apical junctional complex-associated proteins in feline and human corneal endothelium
Q33929929The structure of cell adhesion molecule uvomorulin. Insights into the molecular mechanism of Ca2+-dependent cell adhesion
Q36222150The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium
Q47403727The temporospatial expression of peripheral myelin protein 22 at the developing blood-nerve and blood-brain barriers
Q57075871The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next
Q35777543The tight junction: a multifunctional complex
Q36531649The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties
Q36221153Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance
Q28145432Tight junctions of the blood-brain barrier
Q24292730Tight junctions of the blood-brain barrier: development, composition and regulation
Q36400271Tight junctions: molecular architecture and function
Q40933970Translocation of MARCKS and reorganization of the cytoskeleton by PMA correlates with the ion selectivity, the confluence, and transformation state of kidney epithelial cell lines
Q40835205Urea signaling to ERK phosphorylation in renal medullary cells requires extracellular calcium but not calcium entry
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