Role of nectin in organization of tight junctions in epithelial cells

scientific article published on October 2002

Role of nectin in organization of tight junctions in epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1365-2443.2002.00578.X
P698PubMed publication ID12354099
P5875ResearchGate publication ID11103486

P2093author name stringYoshimi Takai
Kenji Irie
Hiroyuki Nakanishi
Atsunori Fukuhara
Kazuya Shimizu
Akio Yamada
Tomoyuki Honda
Tatsuo Katata
P2860cites workPonsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctionsQ22009075
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing proteinQ22009475
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cellsQ22253974
Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasiaQ22254749
A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies virusQ24313102
The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctionsQ24316928
Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptorQ24322090
alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsQ24322872
The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopyQ24336066
Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein DQ24524264
Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB)Q24524818
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Q24534460
The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein DQ24658082
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctionsQ24669667
Regulation of cadherin adhesive activityQ24669932
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctionsQ24672971
Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin FilamentsQ24678389
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionQ24678766
Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudinsQ24682136
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludinQ24682664
ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludinQ24683294
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Localization of mLin-7 at nectin-based cell-cell junctionsQ40736232
Exogenous expression of the amino-terminal half of the tight junction protein ZO-3 perturbs junctional complex assemblyQ40842719
Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cellsQ41075647
A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptideQ41498808
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblastsQ42796669
Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion mediumQ43107902
Nectin Couples Cell-Cell Adhesion and the Actin Scaffold at Heterotypic Testicular JunctionsQ58549929
Role of the second immunoglobulin-like loop of nectin in cell–cell adhesionQ58549993
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and alpha cateninQ28137655
Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3Q28138745
Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cellsQ28139380
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludinQ28139702
Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activitiesQ28140327
Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interactionQ28141669
Cell adhesion: the molecular basis of tissue architecture and morphogenesisQ28276573
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complexQ28289033
The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH geneQ28294076
Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding geneQ28300125
The 102 kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expressionQ28302135
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsQ28511190
Nectin: an adhesion molecule involved in formation of synapsesQ28577101
Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interactionQ28592530
Cadherin cell adhesion receptors as a morphogenetic regulatorQ29620503
Occludin and claudins in tight-junction strands: leading or supporting players?Q33659718
Structural and signalling molecules come together at tight junctionsQ33744924
The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells.Q34051754
Three classes of cell surface receptors for alphaherpesvirus entryQ34052577
Regulated assembly of tight junctions by protein kinase CQ34182877
Sorting of membrane and fluid at the apical pole of polarized Madin-Darby canine kidney cellsQ34727037
Molecular linkage between cadherins and actin filaments in cell-cell adherens junctionsQ35455510
Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. I. Biochemical analysisQ36218695
Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. II. Morphological analysisQ36218723
Localization of the tight junction protein, ZO-1, is modulated by extracellular calcium and cell-cell contact in Madin-Darby canine kidney epithelial cellsQ36221082
Assembly of the tight junction: the role of diacylglycerolQ36233397
Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma lineQ36234689
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane proteinQ36237286
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesisQ36316682
The cytoplasmic domain of adherens-type junctionsQ36848306
alpha-catenin-independent recruitment of ZO-1 to nectin-based cell-cell adhesion sites through afadinQ38761856
Requirement of interaction of nectin-1alpha/HveC with afadin for efficient cell-cell spread of herpes simplex virus type 1.Q39602751
P433issue10
P304page(s)1059-1072
P577publication date2002-10-01
P1433published inGenes to CellsQ1524078
P1476titleRole of nectin in organization of tight junctions in epithelial cells
P478volume7

Reverse relations

cites work (P2860)
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Q24320219ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions
Q35185942Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells
Q36316720Advances in nasal drug delivery through tight junction technology
Q24311876Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection
Q28575716Contacts between the commissural axons and the floor plate cells are mediated by nectins
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Q36752961De novo lumen formation and elongation in the developing nephron: a central role for afadin in apical polarity
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Q34786013Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment
Q54943207Fc engineering of anti-Nectin-2 antibody improved thrombocytopenic adverse event in monkey.
Q39897873Generation of herpesvirus entry mediator (HVEM)-restricted herpes simplex virus type 1 mutant viruses: resistance of HVEM-expressing cells and identification of mutations that rescue nectin-1 recognition
Q35043947Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain
Q36955176In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa
Q36823573Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects
Q42802396Interaction of integrin alpha(v)beta3 with nectin. Implication in cross-talk between cell-matrix and cell-cell junctions
Q40126640Involvement of integrin-induced activation of protein kinase C in the formation of adherens junctions.
Q52550111Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells.
Q40485882Involvement of the annexin II-S100A10 complex in the formation of E-cadherin-based adherens junctions in Madin-Darby canine kidney cells
Q30157022Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells
Q93079977Long Non-Coding RNAs Modulate Sjögren's Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease
Q24293475Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact
Q39083230Nectin and junctional adhesion molecule are critical cell adhesion molecules for the apico-basal alignment of adherens and tight junctions in epithelial cells.
Q37138803Nectin proteins are expressed at early stages of nephrogenesis and play a role in renal epithelial cell morphogenesis.
Q24294932Nectin-2 is a potential target for antibody therapy of breast and ovarian cancers
Q44419574Nectin-dependent localization of ZO-1 at puncta adhaerentia junctions between the mossy fiber terminals and the dendrites of the pyramidal cells in the CA3 area of adult mouse hippocampus.
Q34220056Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization.
Q28513978PERP regulates enamel formation via effects on cell-cell adhesion and gene expression
Q34520797PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins
Q43109201Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules
Q40642345Regulation by nectin of the velocity of the formation of adherens junctions and tight junctions.
Q33863571Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.
Q40338912Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells
Q40293957Requirement of nectin, but not cadherin, for formation of claudin-based tight junctions in annexin II-knockdown MDCK cells
Q40522184Requirement of the actin cytoskeleton for the association of nectins with other cell adhesion molecules at adherens and tight junctions in MDCK cells.
Q34359173Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex
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Q37267715The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.
Q28512798The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice
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