Tight junction dynamics: the role of junctional adhesion molecules (JAMs).

scientific article published on 05 March 2014

Tight junction dynamics: the role of junctional adhesion molecules (JAMs). is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1025497057
P356DOI10.1007/S00441-014-1820-1
P698PubMed publication ID24595739
P5875ResearchGate publication ID260527762

P2093author name stringB A Imhof
P F Bradfield
S Garrido-Urbani
P2860cites workCTX, a Xenopus thymocyte receptor, defines a molecular family conserved throughout vertebratesQ22008576
Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cellsQ22253974
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structuresQ24290938
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junctionQ24291966
Tight junctions of the blood-brain barrier: development, composition and regulationQ24292730
Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophilsQ24299261
A role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growthQ24301014
The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junctionQ24303832
JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cellsQ24309293
JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier functionQ24311647
Role of junctional adhesion molecule-like protein in mediating monocyte transendothelial migrationQ24336989
Junctional adhesion molecule-C is a soluble mediator of angiogenesisQ24337026
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Q24534460
Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cellsQ44186947
JAM-C induces endothelial cell permeability through its association and regulation of {beta}3 integrins.Q46001649
Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammationQ46811079
Duplication and MHC linkage of the CTX family of genes in Xenopus and in mammalsQ47715242
Differences in expression of junctional adhesion molecule-A and beta-catenin in multiple sclerosis brain tissue: increasing evidence for the role of tight junction pathology.Q48402886
Antibody blockade of junctional adhesion molecule-A in rabbit corneal endothelial tight junctions produces corneal swellingQ50093150
JAM-A mediates neutrophil transmigration in a stimulus-specific manner in vivo: evidence for sequential roles for JAM-A and PECAM-1 in neutrophil transmigration.Q50335792
Relationship between the soluble F11 receptor and markers of inflammation in hemodialysis patients.Q51754166
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.Q51788052
Antibodies to the junctional adhesion molecule cause disruption of endothelial cells and do not prevent leukocyte influx into the meninges after viral or bacterial infection.Q52540557
Homophilic interaction of junctional adhesion molecule.Q52581140
Human Coxsackie-Adenovirus Receptor Is Colocalized With Integrins αvβ3and αvβ5on the Cardiomyocyte Sarcolemma and Upregulated in Dilated CardiomyopathyQ56567622
Inactivation of Junctional Adhesion Molecule-A Enhances Antitumoral Immune Response by Promoting Dendritic Cell and T Lymphocyte InfiltrationQ56942466
aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarizationQ58323641
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctionsQ24669667
The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1Q24673214
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
Junctions between intimately apposed cell membranes in the vertebrate brainQ24682725
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motifQ27634027
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus bindingQ27640992
Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cellsQ28139380
Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cellsQ28140550
A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactionsQ28143886
Expression of the adenovirus receptor and its interaction with the fiber knobQ28144371
Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriersQ28144562
Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptorQ28190701
A transmembrane tight junction protein selectively expressed on endothelial cells and plateletsQ28201696
Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding propertiesQ28202099
Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migrationQ28202579
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion moleculeQ28203316
Junction adhesion molecule is a receptor for reovirusQ28203704
The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarityQ28204763
JAM2 interacts with alpha4beta1. Facilitation by JAM3Q28205206
Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cellsQ28208656
Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family membersQ28209920
Multifunctional strands in tight junctionsQ28210051
Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3Q28217178
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeletonQ28287040
The immunoglobulin superfamily--domains for cell surface recognitionQ28294978
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5Q28303765
Coxsackievirus and adenovirus receptor (CAR) is expressed in male germ cells and forms a complex with the differentiation factor JAM-C in mouse testisQ28505322
JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1Q28506613
Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesionQ28587829
JAM-C regulates tight junctions and integrin-mediated cell adhesion and migrationQ28588755
Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-CQ28589240
Lymphocyte homing and homeostasisQ29619924
Junctional complexes in various epitheliaQ29620435
JAM-C regulates unidirectional monocyte transendothelial migration in inflammationQ30480098
The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivoQ30502906
The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).Q33289422
Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivoQ33501329
Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartmentQ33591084
Claudins in occluding junctions of humans and fliesQ33994147
Fracture faces of zonulae occludentes from "tight" and "leaky" epitheliaQ34051800
Fine structural localization of a blood-brain barrier to exogenous peroxidaseQ34054533
A homozygous mutation in the tight-junction protein JAM3 causes hemorrhagic destruction of the brain, subependymal calcification, and congenital cataractsQ34151916
Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalusQ34429627
Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in miceQ34571265
JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cellsQ34646874
The JAM family of proteinsQ34650444
The cytoplasmic plaque of tight junctions: a scaffolding and signalling centerQ34761497
Complex phenotype of mice lacking occludin, a component of tight junction strands.Q34781594
Mechanisms of HIV entry into the CNS: increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in diapedesisQ34902401
A CTX family cell adhesion molecule, JAM4, is expressed in stem cell and progenitor cell populations of both male germ cell and hematopoietic cell lineagesQ35131498
Forging the endothelium during inflammation: pushing at a half-open door?Q35211628
Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-alpha plus interferon-gamma Does not reduce leukocyte transmigratiQ35747154
aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formationQ35839775
Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasisQ35842988
Junctional adhesion molecule-C regulates vascular endothelial permeability by modulating VE-cadherin-mediated cell-cell contactsQ36228150
ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeabilityQ36228711
JAM-A regulates permeability and inflammation in the intestine in vivoQ36294373
Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM).Q36375485
Claudins and epithelial paracellular transportQ36387912
Coordinated redistribution of leukocyte LFA-1 and endothelial cell ICAM-1 accompany neutrophil transmigrationQ36399827
The PAR-aPKC system: lessons in polarityQ36416725
Effects of JAM-A deficiency or blocking antibodies on neutrophil migration and lung injury in a murine model of ALIQ36454409
Compromised intestinal epithelial barrier induces adaptive immune compensation that protects from colitisQ36588077
Mechanisms of Leukocyte Transendothelial MigrationQ36772665
JAM family and related proteins in leukocyte migration (Vestweber series).Q36872202
Biology of claudins.Q36956748
JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activationQ37010686
Vascular and epithelial junctions: a barrier for leucocyte migrationQ37117935
Junctional adhesion molecule-C mediates leukocyte infiltration in response to ischemia reperfusion injury.Q37353304
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A-deficient miceQ37486598
Capture, crawl, cross: the T cell code to breach the blood-brain barriersQ38038445
Endothelial cell-selective adhesion molecule modulates atherosclerosis through plaque angiogenesis and monocyte-endothelial interactionQ39712763
Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity.Q40464555
Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contactsQ40512855
Role of nectin in organization of tight junctions in epithelial cellsQ40700929
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.Q40782848
Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.Q41322935
Molecular architecture of tight junctionsQ41748256
Junctional adhesion molecule C mediates leukocyte adhesion to rheumatoid arthritis synoviumQ41911122
A cell culture model of the blood-brain barrierQ42006322
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblastsQ42796669
Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrinQ43279071
Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula OccludensQ43798217
JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytesQ43867713
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)701-715
P577publication date2014-03-05
P1433published inCell and Tissue ResearchQ1524113
P1476titleTight junction dynamics: the role of junctional adhesion molecules (JAMs).
P478volume355

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cites work (P2860)
Q28551147ADAM10 Is Involved in Cell Junction Assembly in Early Porcine Embryo Development
Q90619843Alterations in Tight- and Adherens-Junction Proteins Related to Glaucoma Mimicked in the Organotypically Cultivated Mouse Retina Under Elevated Pressure
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Q99238065Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders
Q28083498Brain barriers: Crosstalk between complex tight junctions and adherens junctions
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Q92460653Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro
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Q47771280Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Q50214650KirrelL, a member of the Ig-domain superfamily of adhesion proteins, is essential for fusion of primary mesenchyme cells in the sea urchin embryo
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Q55263349Maternal and early-life vitamin D deficiency enhances allergic reaction in an ovalbumin-sensitized BALB/c mouse model.
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