Claudins and epithelial paracellular transport

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Claudins and epithelial paracellular transport is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV.PHYSIOL.68.040104.131404
P698PubMed publication ID16460278

P2093author name stringJames M Anderson
Christina M Van Itallie
P304page(s)403-429
P577publication date2006-01-01
P1433published inAnnual Review of PhysiologyQ567364
P1476titleClaudins and epithelial paracellular transport
P478volume68

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cites work (P2860)
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Q46243652Evidence for a role of tight junctions in regulating sodium permeability in zebrafish (Danio rerio) acclimated to ion-poor water
Q37710221Evidence for intestinal chloride secretion
Q45366167Examination of claudin-1 expression in patients undergoing liver transplantation owing to hepatitis C virus cirrhosis
Q44934388Exogenous GDF9 but not Activin A, BMP15 or TGFβ alters tight junction protein transcript abundance in zebrafish ovarian follicles
Q28506564Expression of TM4SF10, a Claudin/EMP/PMP22 family cell junction protein, during mouse kidney development and podocyte differentiation
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Q36095370Expression of claudin-5, -7, -8 and -9 in cervical carcinoma tissues and adjacent non-neoplastic tissues
Q36619284Expression of claudins -2 and -4 and cingulin is coordinated with the start of stratification and differentiation in corneal epithelial cells: retinoic acid reversibly disrupts epithelial barrier.
Q79680779Expression patterns of claudin family of tight-junction proteins in the mouse prostate
Q42037705Extracellular matrix influences alveolar epithelial claudin expression and barrier function
Q37445720FACS-assisted microarray profiling implicates novel genes and pathways in zebrafish gastrointestinal tract development
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Q37545188FigA, a putative homolog of low-affinity calcium system member Fig1 in Saccharomyces cerevisiae, is involved in growth and asexual and sexual development in Aspergillus nidulans.
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Q37151668Function and regulation of claudins in the thick ascending limb of Henle
Q38274629Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells
Q35950310Functional characterization and localization of a gill-specific claudin isoform in Atlantic salmon
Q37783437Functions of Claudin Tight Junction Proteins and Their Complex Interactions in Various Physiological Systems
Q35247591Further analysis of the lens phenotype in Lim2-deficient mice
Q36858886Gap junction communication influences intercellular protein distribution in the lens
Q36824309Gap junctional proteins of animals: the innexin/pannexin superfamily
Q40458744Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury.
Q53336830Gene expression analysis of early and advanced gastric cancers.
Q36284736Gene expression plasticity in response to salinity acclimation in threespine stickleback ecotypes from different salinity habitats
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Q28731289Genetic divergence between freshwater and marine morphs of alewife (Alosa pseudoharengus): a 'next-generation' sequencing analysis
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Q42486132Glucagon-Like Peptide-1 Strengthens the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells Under Basal and Hyperglycemia Conditions.
Q45743243Glucocorticoids regulate barrier function and claudin expression in intestinal epithelial cells via MKP-1.
Q35616074Gut microbiome, gut function, and probiotics: Implications for health.
Q36764934High Expression of the Newly Found Long Noncoding RNA Z38 Promotes Cell Proliferation and Oncogenic Activity in Breast Cancer
Q26768428Homeostatic Signaling by Cell-Cell Junctions and Its Dysregulation during Cancer Progression
Q54368244Host defense (Antimicrobial) peptide, human β-defensin-3, improves the function of the epithelial tight-junction barrier in human keratinocytes.
Q36551884Human claudin-8 and -14 are receptors capable of conveying the cytotoxic effects of Clostridium perfringens enterotoxin
Q24312952Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway
Q36949030Hypertonic stress increases claudin-4 expression and tight junction integrity in association with MUPP1 in IMCD3 cells
Q40153022Hypoxia disrupts the barrier function of neural blood vessels through changes in the expression of claudin-5 in endothelial cells
Q35126950IQGAP1 controls tight junction formation through differential regulation of claudin recruitment
Q24293163Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family
Q33557833Identification of a claudin-4 residue important for mediating the host cell binding and action of Clostridium perfringens enterotoxin
Q42590043Immunohistochemical profiles of claudin-3 in primary and metastatic prostatic adenocarcinoma.
Q92372570Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650
Q53697270In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases.
Q28577922Increase in the tight junction protein claudin-1 in intestinal inflammation
Q46335134Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis
Q35705366Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice
Q28550435Inhibition of Matriptase Activity Results in Decreased Intestinal Epithelial Monolayer Integrity In Vitro
Q39824870Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
Q52598001Inhibition of hepatitis C virus infection by anti-claudin-1 antibodies is mediated by neutralization of E2-CD81-claudin-1 associations.
Q39379865Inhibition of matrix metalloproteinase activities and tightening of tight junctions by diallyl disulfide in AGS human gastric carcinoma cells
Q38013747Innate Immunity in the Small Intestine of the Preterm Infant
Q92594507Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis
Q27660107Insights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase Module
Q35646965Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex
Q39371803Interferon-gamma signals via an ERK1/2-ARF6 pathway to promote bacterial internalization by gut epithelia.
Q34357091Interleukin-13-induced mucous metaplasia increases susceptibility of human airway epithelium to rhinovirus infection.
Q39217461Interplay between tight junctions & adherens junctions.
Q38757951Intestinal Barrier Disturbances in Haemodialysis Patients: Mechanisms, Consequences, and Therapeutic Options.
Q89886066Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development
Q92356819Intestinal barrier dysfunction in severe burn injury
Q28250081Intestinal barrier function: molecular regulation and disease pathogenesis
Q50600432Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice.
Q39298268Intestinal epithelial claudins: expression and regulation in homeostasis and inflammation
Q47104884Intestinal epithelium, intraepithelial lymphocytes and the gut microbiota - Key players in the pathogenesis of celiac disease.
Q36285527Intestinal fluid absorption in anadromous salmonids: importance of tight junctions and aquaporins
Q24629228Intestinal permeability defects: is it time to treat?
Q26859272Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases
Q39036430Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit.
Q37859562Ion regulation in fish gills: recent progress in the cellular and molecular mechanisms
Q80726768It takes guts to make a single lumen
Q41847742JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells.
Q36294373JAM-A regulates permeability and inflammation in the intestine in vivo
Q38199343JAM-related proteins in mucosal homeostasis and inflammation
Q47771280Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Q42085912Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus
Q40241931Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains
Q34426070Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells
Q39904783Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells
Q34103720Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis
Q57027399Lack of Vitamin D Receptor Leads to Hyperfunction of Claudin-2 in Intestinal Inflammatory Responses
Q48112535Lactobacillus plantarum Restores Intestinal Permeability Disrupted by Salmonella Infection in Newly-hatched Chicks.
Q34587671Lactobacillus rhamnosus strain GG prevents enterohemorrhagic Escherichia coli O157:H7-induced changes in epithelial barrier function
Q38002767Lecture: New light on the role of claudins in the kidney
Q84804457Long-term swimming in an inescapable stressful environment attenuates the stimulatory effect of endurance swimming on duodenal calcium absorption in rats
Q84779796Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
Q50197299Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo
Q24338226MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival
Q33732689Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine
Q50521398Methods to examine tight junction physiology in cancer stem cells: TEER, paracellular permeability, and dilution potential measurements.
Q35595622MicroRNA-204/211 alters epithelial physiology
Q38328002MicroRNAs regulate tight junction proteins and modulate epithelial/endothelial barrier functions.
Q38219024MicroRNAs: New therapeutic targets for intestinal barrier dysfunction
Q92544141Microbe and host interaction in gastrointestinal homeostasis
Q33913522Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse.
Q33938278Minimal effects of VEGF and anti-VEGF drugs on the permeability or selectivity of RPE tight junctions.
Q37982360Modulation of tight junction structure and function by kinases and phosphatases targeting occludin
Q35919870Molecular and cellular mechanisms of tight junction dysfunction in the irritable bowel syndrome
Q37023274Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site
Q33685399Molecular basis of the core structure of tight junctions
Q37123833Molecular determinants of magnesium homeostasis: insights from human disease
Q89143916Molecular determination of claudin-15 organization and channel selectivity
Q33983087Molecular organization of tricellular tight junctions
Q37810004Morphology and Properties of Brain Endothelial Cells
Q34886111Multiple signaling pathways regulate yeast cell death during the response to mating pheromones
Q24672137Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure, and severe ocular involvement
Q30432116Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules
Q30581661Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease
Q30513859Myosin-X functions in polarized epithelial cells
Q27004163Myosins in cell junctions
Q40234364Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells
Q36235912Necrotizing enterocolitis in a mouse model leads to widespread renal inflammation, acute kidney injury, and disruption of renal tight junction proteins
Q37360580New diagnostic and molecular characteristics of malignant mesothelioma
Q30489770New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8.
Q27935146New regulators of a high affinity Ca2+ influx system revealed through a genome-wide screen in yeast
Q37107696New ways of thinking about (and teaching about) intestinal epithelial function
Q92820010Newly synthesized claudins but not occludin are added to the basal side of the tight junction
Q39587450Non-proteolytic house dust mite allergen, Der p 2, upregulated expression of tight junction molecule claudin-2 associated with Akt/GSK-3β/β-catenin signaling pathway.
Q38333207Normalization genes for quantitative RT-PCR in differentiated Caco-2 cells used for food exposure studies
Q39027079Novel pharmacologic targeting of tight junctions and focal adhesions in prostate cancer cells
Q34305517Nucleofection disrupts tight junction fence function to alter membrane polarity of renal epithelial cells
Q42674517Observation of the middle intestinal tight junction structure, cloning and studying tissue distribution of the four Claudin genes of the grass carp (Ctenopharyngodon idellus).
Q36647390Occludin deficiency promotes ethanol-induced disruption of colonic epithelial junctions, gut barrier dysfunction and liver damage in mice
Q34043395Occludin is required for cytokine-induced regulation of tight junction barriers
Q35057031Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier
Q39852938Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells
Q40145744Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions
Q52723966Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes.
Q34009441Organization and function of the blood-brain barrier in Drosophila.
Q37118549Organization of multiprotein complexes at cell-cell junctions
Q33336226Organization of the pronephric kidney revealed by large-scale gene expression mapping.
Q37898569Osmoregulation and epithelial water transport: lessons from the intestine of marine teleost fish
Q38203222Osmoregulation and excretion
Q93186070Osmoregulation in Barnacles: An Evolutionary Perspective of Potential Mechanisms and Future Research Directions
Q80951780Osteoblasts express claudins and tight junction-associated proteins
Q46570774Oxidative stress-induced disruption of epithelial and endothelial tight junctions.
Q24643377Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctions
Q57129163Parathyroid hormone (PTH) rapidly enhances CFTR-mediated HCO₃⁻ secretion in intestinal epithelium-like Caco-2 monolayer: a novel ion regulatory action of PTH
Q39723716Participation of the second extracellular loop of claudin-5 in paracellular tightening against ions, small and large molecules
Q26852773Pathways and progress in improving drug delivery through the intestinal mucosa and blood-brain barriers
Q28270069Physiology and function of the tight junction
Q43176433Pitavastatin strengthens the barrier integrity in primary cultures of rat brain endothelial cells
Q37967680Possible involvement of tight junctions, extracellular matrix and nuclear receptors in epithelial differentiation
Q54312616Potential mechanisms explaining why hydrolyzed casein-based diets outclass single amino acid-based diets in the prevention of autoimmune diabetes in diabetes-prone BB rats.
Q37248478Potentiometric-scanning ion conductance microscopy for measurement at tight junctions
Q37620365Preclinical models for pulmonary drug delivery
Q28513418Predicted expansion of the claudin multigene family
Q51567089Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction.
Q58186380Probing effects of pH change on dynamic response of Claudin-2 mediated adhesion using single molecule force spectroscopy
Q33410108Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis
Q47584454Process of tight junction recovery in the injured vocal fold epithelium: Morphological and paracellular permeability analysis.
Q36815936Progress in absorption enhancers based on tight junction
Q36933197Prolactin is an important regulator of intestinal calcium transport
Q40000478Prolactin stimulates transepithelial calcium transport and modulates paracellular permselectivity in Caco-2 monolayer: mediation by PKC and ROCK pathways
Q38021496Proof of concept for claudin-targeted drug development
Q34081941Protein kinase C activation has distinct effects on the localization, phosphorylation and detergent solubility of the claudin protein family in tight and leaky epithelial cells
Q37415698Protein kinase D promotes airway epithelial barrier dysfunction and permeability through down-regulation of claudin-1
Q38265533Protein kinases are potential targets to treat inflammatory bowel disease
Q58438267Protein myozap — a late addition to the molecular ensembles of various kinds of adherens junctions
Q36680569Rab25 regulates integrin expression in polarized colonic epithelial cells
Q28250836RalA and RalB differentially regulate development of epithelial tight junctions
Q35919800Recent advances in our understanding of 1,25-dihydroxyvitamin D(3) regulation of intestinal calcium absorption
Q38190079Recent progress in tight junction modulation for improving bioavailability
Q38003426Recent trends in oral transmucosal drug delivery systems: an emphasis on the soft palatal route
Q37423257Regulation and roles for claudin-family tight junction proteins
Q37389718Regulation of Endothelial Permeability in the Corpus Luteum: A Review of the Literature
Q91994983Regulation of Epithelial Cell Functions by the Osmolality and Hydrostatic Pressure Gradients: A Possible Role of the Tight Junction as a Sensor
Q24609784Regulation of cell-cell adhesion by the cadherin-catenin complex
Q47879381Regulation of claudin-4 via p63 in human epithelial cells
Q34287155Regulation of intestinal epithelial permeability by tight junctions.
Q39454371Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b.
Q37903873Regulation of small GTPases at epithelial cell-cell junctions
Q90705632Regulation of the intestinal barrier by nutrients: The role of tight junctions
Q39336324Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cells
Q36450027Regulation of transport in the connecting tubule and cortical collecting duct
Q37438622Remodeling of the tight junction during recovery from exposure to hydrogen peroxide in kidney epithelial cells
Q33589127Renal salt wasting and chronic dehydration in claudin-7-deficient mice
Q27488396Residues in a Highly Conserved Claudin-1 Motif Are Required for Hepatitis C Virus Entry and Mediate the Formation of Cell-Cell Contacts
Q34283907Restoration of impaired intestinal barrier function by the hydrolysed casein diet contributes to the prevention of type 1 diabetes in the diabetes-prone BioBreeding rat
Q40120136Restriction of sulfur-containing amino acids alters claudin composition and improves tight junction barrier function
Q37800133Review: Molecular pathogenesis of blood–brain barrier breakdown in acute brain injury
Q93053740Review: Peering through a keyhole: liquid biopsy in primary and metastatic central nervous system tumours
Q37687727Rho signaling and tight junction functions
Q34468725Role of Glutamine in Protection of Intestinal Epithelial Tight Junctions
Q64095835Role of Low-Affinity Calcium System Member Fig1 Homologous Proteins in Conidiation and Trap-Formation of Nematode-trapping Fungus Arthrobotrys oligospora
Q34888133Role of claudin species-specific dynamics in reconstitution and remodeling of the zonula occludens
Q34236962Role of microRNAs in controlling gene expression in different segments of the human epididymis
Q53159348Role of post translational modifications and novel crosstalk between phosphorylation and O-beta-GlcNAc modifications in human claudin-1, -3 and -4.
Q38407509Role of the Cldn6 cytoplasmic tail domain in membrane targeting and epidermal differentiation in vivo
Q35006945SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.
Q28269524SUMOylation of claudin-2
Q44872574Salinity regulates claudin mRNA and protein expression in the teleost gill.
Q40092371Scaffolding protein GOPC regulates tight junction structure.
Q36828527Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions
Q36541724Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot-Marie-Tooth disease).
Q36483860Segmental Differences in Radiation-Induced Alterations of Tight Junction-Related Proteins in Non-Human Primate Jejunum, Ileum and Colon
Q37295746Sequential biphasic changes in claudin1 and claudin4 expression are correlated to colorectal cancer progression and liver metastasis
Q43884308Serine proteases decrease intestinal epithelial ion permeability by activation of protein kinase Czeta
Q36060658Spatial distributions of phosphorylated membrane proteins aquaporin 0 and MP20 across young and aged human lenses
Q35111744Specialized metabolites from the microbiome in health and disease
Q35155903Specificity of interaction between clostridium perfringens enterotoxin and claudin-family tight junction proteins
Q38898593Strengthening of the intestinal epithelial tight junction by Bifidobacterium bifidum
Q37419733Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling
Q27671708Structure of the Food-Poisoning Clostridium perfringens Enterotoxin Reveals Similarity to the Aerolysin-Like Pore-Forming Toxins
Q37431293Structure-function studies of claudin extracellular domains by cysteine-scanning mutagenesis.
Q40224183Study of claudin function by RNA interference
Q34079643Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.
Q33664419Symplekin promotes tumorigenicity by up-regulating claudin-2 expression
Q36012269Synapses: sites of cell recognition, adhesion, and functional specification.
Q37756991Systemic delivery of therapeutics to neuronal tissues: a barrier modulation approach
Q28271194Systems Proteomics View of the Endogenous Human Claudin Protein Family
Q37699264Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer
Q38242808Targeting tight junctions during epithelial to mesenchymal transition in human pancreatic cancer.
Q90461439Temporal Effects of Quercetin on Tight Junction Barrier Properties and Claudin Expression and Localization in MDCK II Cells
Q92286639Testosterone Reduces Tight Junction Complexity and Down-regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-steroid Replacement Rats
Q55428227The Claudin Family Protein FigA Mediates Ca2+ Homeostasis in Response to Extracellular Stimuli in Aspergillus nidulans and Aspergillus fumigatus.
Q58795929The Claudin-like Protein HPO-30 Is Required to Maintain LAChRs at the Neuromuscular Junction
Q34007920The Drosophila Claudin Kune-kune is required for septate junction organization and tracheal tube size control.
Q61451727The In Vitro Protective Role of Bovine Lactoferrin on Intestinal Epithelial Barrier
Q91762443The Kiwifruit Allergen Act d 1 Activates NF-κB Signaling and Affects mRNA Expression of TJ Proteins and Innate Pro-Allergenic Cytokines
Q37123846The Na⁺/H⁺ exchanger isoform 3 is required for active paracellular and transcellular Ca²⁺ transport across murine cecum
Q27939681The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans
Q33740929The Yin and Yang of bile acid action on tight junctions in a model colonic epithelium
Q46220466The antimicrobial protein S100A7/psoriasin enhances the expression of keratinocyte differentiation markers and strengthens the skin's tight junction barrier
Q33619070The apical junctional complex in respiratory diseases
Q39407129The barrier hypothesis and Oncostatin M: Restoration of epithelial barrier function as a novel therapeutic strategy for the treatment of type 2 inflammatory disease
Q34931170The blood-brain barrier
Q38594314The blood-epididymis barrier and inflammation
Q39044859The choroid plexus as a sex hormone target: Functional implications
Q37350823The claudins
Q37813173The diagnostic and molecular characteristics of malignant mesothelioma and ovarian/peritoneal serous carcinoma
Q40383479The four-transmembrane protein IP39 of Euglena forms strands by a trimeric unit repeat.
Q87954480The human cathelicidin LL-37 host defense peptide upregulates tight junction-related proteins and increases human epidermal keratinocyte barrier function
Q39090532The interaction between claudin-1 and dengue viral prM/M protein for its entry
Q39009998The intestinal epithelial barrier: a therapeutic target?
Q37738570The landscape of extreme genomic variation in the highly adaptable Atlantic killifish
Q37986624The matriptase-prostasin proteolytic cascade in epithelial development and pathology
Q41995604The peripheral neuropathy-linked Trembler and Trembler-J mutant forms of peripheral myelin protein 22 are folding-destabilized
Q89440743The regulation of junctional actin dynamics by cell adhesion receptors
Q27007776The role of Haptoglobin and its related protein, Zonulin, in inflammatory bowel disease
Q34962777The role of aquaporin and tight junction proteins in the regulation of water movement in larval zebrafish (Danio rerio)
Q27026767The role of claudin in hypercalciuric nephrolithiasis
Q40052094The role of transcriptional factor p63 in regulation of epithelial barrier and ciliogenesis of human nasal epithelial cells
Q30487542The stratified syncytium of the vertebrate lens.
Q42519731The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities
Q37457219The tight junction in inflammatory disease: communication breakdown
Q39503554The tight junction protein claudin-3 shows conserved expression in the nephric duct and ureteric bud and promotes tubulogenesis in vitro
Q30538920The tight junction protein claudin-b regulates epithelial permeability and sodium handling in larval zebrafish, Danio rerio
Q35962975The tight junction protein, MUPP1, is up-regulated by hypertonicity and is important in the osmotic stress response in kidney cells
Q24652906The tight junction proteins claudin-1, -6, and -9 are entry cofactors for hepatitis C virus
Q35014381The tight-junction protein claudin-6 induces epithelial differentiation from mouse F9 and embryonic stem cells
Q43240827The two-membrane model of epithelial transport: Koefoed-Johnsen and Ussing (1958).
Q37557245Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N,N'-bis-2-
Q54446299Thymic stromal lymphopoietin induces tight junction protein claudin-7 via NF-kappaB in dendritic cells.
Q28073886Tight Junction Disruption Induced by Type 3 Secretion System Effectors Injected by Enteropathogenic and Enterohemorrhagic Escherichia coli
Q36305755Tight Junction Pore and Leak Pathways: A Dynamic Duo
Q60952879Tight Junction in the Intestinal Epithelium: Its Association with Diseases and Regulation by Phytochemicals
Q92354281Tight Junctions of the Outer Blood Retina Barrier
Q36293734Tight junction CLDN2 gene is a direct target of the vitamin D receptor
Q37038324Tight junction composition is altered in the epithelium of polycystic kidneys
Q34629278Tight junction defects in patients with atopic dermatitis.
Q38193357Tight junction dynamics: the role of junctional adhesion molecules (JAMs).
Q27012765Tight junction proteins and oxidative stress in heavy metals-induced nephrotoxicity
Q42985802Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.
Q43018186Tight junction proteins in zebrafish ovarian follicles: stage specific mRNA abundance and response to 17beta-estradiol, human chorionic gonadotropin, and maturation inducing hormone
Q37333599Tight junction-based epithelial microenvironment and cell proliferation
Q38077200Tight junction-related human diseases
Q51973279Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.
Q46779417Tight junctions in Gerbil von Ebner's gland: horseradish peroxidase and freeze-fracture studies
Q27012318Tight junctions in human pancreatic duct epithelial cells
Q33674271Tight junctions in salivary epithelium
Q37733955Tight junctions in the testis: new perspectives.
Q37420725Tight junctions: a barrier to the initiation and progression of breast cancer?
Q47073598Tjp3/zo-3 is critical for epidermal barrier function in zebrafish embryos
Q89744172Total Flavonoid Extract from Hawthorn (Crataegus pinnatifida) Improves Inflammatory Cytokines-Evoked Epithelial Barrier Deficit
Q36890396Toxin plasmids of Clostridium perfringens.
Q40046453Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells
Q34033442Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells
Q36095797Transcriptional modulation of genes encoding structural characteristics of differentiating enterocytes during development of a polarized epithelium in vitro
Q42440926Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes.
Q28511757Tricellulin deficiency affects tight junction architecture and cochlear hair cells.
Q24337885Tricellulin is a tight-junction protein necessary for hearing
Q48157550Tumor Necrosis Factor-α Increases Claudin-1, 4, and 7 Expression in Tubular Cells: Role in Permeability Changes
Q41460133Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions
Q40262405Two splice variants of claudin-10 in the kidney create paracellular pores with different ion selectivities.
Q54735441Two-step stimulation of intestinal Ca(2+) absorption during lactation by long-term prolactin exposure and suckling-induced prolactin surge.
Q42362918Up-regulation of claudin-2 expression by aldosterone in colonic epithelial cells of mice fed with NaCl-depleted diets.
Q89862050Upregulation of Claudin-7 Expression by Angiotensin II in Colonic Epithelial Cells of Mice Fed with NaCl-Depleted Diets
Q38130285Uriniferous tubule: structural and functional organization
Q51062851Value of claudin-4 immunostaining in the diagnosis of mesothelioma.
Q41602366Vasoactive intestinal peptide prevents PKCε-induced intestinal epithelial barrier disruption during EPEC infection.
Q34367448Whole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation.
Q38730627Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis
Q38734544ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture.
Q30157199ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton
Q46067401Zinc supplementation modifies tight junctions and alters barrier function of CACO-2 human intestinal epithelial layers
Q37387966Zona occludens-2 is critical for blood-testis barrier integrity and male fertility
Q37239701[6]-Gingerol Prevents Disassembly of Cell Junctions and Activities of MMPs in Invasive Human Pancreas Cancer Cells through ERK/NF- κ B/Snail Signal Transduction Pathway
Q61798329gene knockout causes destruction of intestinal structure and animal death in mice
Q38110520miRNA in the regulation of ion channel/transporter expression

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