Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains

scientific article published on 21 July 2006

Junctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2006.07.004
P698PubMed publication ID16919624

P50authorDietmar VestweberQ98408
Klaus EbnetQ57092219
Sandra IdenQ59543270
P2093author name stringDaniela Rehder
Joachim Wegener
Ines Nasdala
Maria-Katharina Meyer Zu Brickwedde
P2860cites workPonsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctionsQ22009075
Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structuresQ24290938
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junctionQ24291966
The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs LostQ24293049
The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial cellsQ24299510
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)Q24534460
MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesionQ24540244
CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cellsQ24632780
Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctionsQ24669667
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionQ24678766
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cellsQ24679401
Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigrationQ24682572
X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motifQ27634027
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus bindingQ27640992
Rho GTPases in cell biologyQ27860969
Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludinQ28139702
Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cellsQ28140550
A transmembrane tight junction protein selectively expressed on endothelial cells and plateletsQ28201696
Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1)Q28202982
Multi-PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion moleculeQ28203316
Junction adhesion molecule is a receptor for reovirusQ28203704
Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development.Q52174756
Rap1 GTPase regulation of adherens junction positioning and cell adhesion.Q52545327
Involvement of the junctional adhesion molecule-1 (JAM1) homodimer interface in regulation of epithelial barrier function.Q52553035
Homophilic interaction of junctional adhesion molecule.Q52581140
Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization.Q52602094
Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight JunctionsQ58323630
aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarizationQ58323641
Junctional adhesion molecule (JAM) is phosphorylated by protein kinase C upon platelet activationQ73067244
Signaling through JAM-1 and αvβ3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and αvβ3 complexQ73400614
The JAM family of junctional adhesion moleculesQ28205895
The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cellsQ28207209
Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cellsQ28208656
Multifunctional strands in tight junctionsQ28210051
JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1Q28506613
Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-CQ28589240
Recognition of unique carboxyl-terminal motifs by distinct PDZ domainsQ29547580
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cellsQ30159938
Parsing the polarity codeQ30312126
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.Q30436000
The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complexQ30443412
Claudins in occluding junctions of humans and fliesQ33994147
Nectin and afadin: novel organizers of intercellular junctions.Q34161446
Opinion: Building epithelial architecture: insights from three-dimensional culture modelsQ34718096
Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cellsQ35034031
Epithelial polarity and tubulogenesis in vitro.Q35095561
Adaptation of core mechanisms to generate cell polarityQ35109711
Functional analysis of tight junctionsQ35150365
Junctional adhesion molecules (JAMs): more molecules with dual functions?Q35600846
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane proteinQ36237286
The Ras target AF-6 interacts with ZO-1 and serves as a peripheral component of tight junctions in epithelial cellsQ36276564
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesisQ36316682
PATJ regulates tight junction formation and polarity in mammalian epithelial cellsQ36321518
Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeabilityQ36324231
Claudins and epithelial paracellular transportQ36387912
Loss of PALS1 expression leads to tight junction and polarity defects.Q37221191
Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity.Q40464555
Expression of junctional adhesion molecule-A prevents spontaneous and random motility.Q40469611
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.Q40535764
PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.Q40782848
Characterization of huJAM: evidence for involvement in cell-cell contact and tight junction regulationQ40842464
Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cellsQ40941485
A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblastsQ42796669
Roles of immunoglobulin-like loops of junctional cell adhesion molecule 4; involvement in the subcellular localization and the cell adhesionQ43757423
JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytesQ43867713
Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cellsQ44186947
Integrated activity of PDZ protein complexes regulates epithelial polarityQ44268189
The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarityQ45001884
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.Q45124238
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.Q45249905
CLMP, a novel member of the CTX family and a new component of epithelial tight junctionsQ48222946
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)3389-3403
P577publication date2006-07-21
P1433published inExperimental Cell ResearchQ1524289
P1476titleJunctional adhesion molecule-a participates in the formation of apico-basal polarity through different domains
P478volume312

Reverse relations

cites work (P2860)
Q47214655Analysis of differential expression of tight junction proteins in cultured oral epithelial cells altered by Porphyromonas gingivalis, Porphyromonas gingivalis lipopolysaccharide, and extracellular adenosine triphosphate
Q92135537Cell junctions and oral health
Q38033611Cell polarity as a regulator of cancer cell behavior plasticity
Q36631107Cis-dimerization mediates function of junctional adhesion molecule A.
Q92993434Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity
Q46919125Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain
Q42502292Epithelial Membrane Protein 2 and β1 integrin signaling regulate APC-mediated processes
Q37866083Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment
Q37241585Epithelial junctions and polarity: complexes and kinases
Q37363476Expression, localization, and function of junctional adhesion molecule-C (JAM-C) in human retinal pigment epithelium
Q34066373From cells to organs: building polarized tissue.
Q28481395Genomic organisation, embryonic expression and biochemical interactions of the zebrafish junctional adhesion molecule family of receptors
Q37507256High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor
Q30373402Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurements
Q41847742JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells.
Q33534529JAM-A is a novel surface marker for NG2-Glia in the adult mouse brain
Q40032505JAM-A is both essential and inhibitory to development of hepatic polarity in WIF-B cells
Q36030193JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.
Q36294373JAM-A regulates permeability and inflammation in the intestine in vivo
Q28588755JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration
Q38199343JAM-related proteins in mucosal homeostasis and inflammation
Q47771280Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.
Q40108852Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells
Q37118549Organization of multiprotein complexes at cell-cell junctions
Q37591643Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesis
Q28573180Slit diaphragms contain tight junction proteins
Q39311689Tetraspanin CD9 links junctional adhesion molecule-A to αvβ3 integrin to mediate basic fibroblast growth factor-specific angiogenic signaling
Q92021865The mitochondrial outer membrane protein SYNJ2BP interacts with the cell adhesion molecule TMIGD1 and can recruit it to mitochondria
Q37118065Tight junction proteins: from barrier to tumorigenesis.
Q38637013Unconventional Functions of Mitotic Kinases in Kidney Tumorigenesis
Q39642580Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers
Q35839775aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation

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