Myosin-X functions in polarized epithelial cells

scientific article

Myosin-X functions in polarized epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E11-04-0358
P932PMC publication ID3338435
P698PubMed publication ID22419816

P50authorRichard CheneyQ42703433
P2093author name stringAlan S Fanning
Damon T Jacobs
Katy C Liu
Brian D Dunn
P2860cites workProteomic analysis of the enterocyte brush borderQ24293478
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesionQ24681681
Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domainQ27666969
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Myosin X is a downstream effector of PI(3)K during phagocytosisQ28114999
Mutations in the myosin VIIA gene cause non-syndromic recessive deafnessQ28239749
Physiology and function of the tight junctionQ28270069
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epitheliaQ28299935
Directed actin polymerization is the driving force for epithelial cell-cell adhesionQ29618861
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeletonQ30157199
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cellsQ30159938
Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical PinsQ30430174
Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formationQ30434136
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epitheliaQ30437856
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cellsQ30442081
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contactsQ30476214
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent mannerQ30479119
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.Q30480576
Myosin-10 and actin filaments are essential for mitotic spindle functionQ30482632
A myosin motor that selects bundled actin for motilityQ30482736
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesisQ30484554
Trafficking of Crumbs3 during cytokinesis is crucial for lumen formationQ30491662
The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.Q30493646
An unconventional myosin required for cell polarization and chemotaxisQ30494552
Interactions between actin filaments and between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick earQ30494584
Single-molecule stepping and structural dynamics of myosin X.Q30494681
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
Proteins of the kidney microvillus membrane. Identification of subunits after sodium dodecylsullphate/polyacrylamide-gel electrophoresisQ30988587
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctionsQ33292672
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodiaQ33840016
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.Q33917620
Aquaporins in the kidney: from molecules to medicineQ34107691
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
Adherens junctions: from molecules to morphogenesisQ34122302
Possible involvement of myosin‐X in intercellular adhesion: Importance of serial pleckstrin homology regions for intracellular localizationQ34197708
A gene for congenital, recessive deafness DFNB3 maps to the pericentromeric region of chromosome 17.Q34307634
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complexQ34359173
Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.Q34582966
Calmodulin-like protein increases filopodia-dependent cell motility via up-regulation of myosin-10.Q34585084
MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity.Q34812873
Sticky business: orchestrating cellular signals at adherens junctionsQ35071400
Myosin-X: a MyTH-FERM myosin at the tips of filopodiaQ35576442
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epitheliaQ35756679
The tight junction: a multifunctional complexQ35777543
Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cellsQ36119767
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherensQ36191191
Mechanism of brush border contractility studied by the quick-freeze, deep-etch methodQ36208203
Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane proteinQ36237286
Myosin-X: a molecular motor at the cell's fingertipsQ36248392
Tight Junction Pore and Leak Pathways: A Dynamic DuoQ36305755
PATJ regulates tight junction formation and polarity in mammalian epithelial cellsQ36321518
Claudins and epithelial paracellular transportQ36387912
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptorsQ36639095
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomesQ36843504
Adherens and tight junctions: structure, function and connections to the actin cytoskeletonQ36940193
Actin motors that drive formation and disassembly of epithelial apical junctionsQ37175764
The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblastsQ39674089
Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cellsQ39735805
The role of uvomorulin in the formation of epithelial occluding junctionsQ39761194
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
Mechanism of action of myosin X, a membrane-associated molecular motor.Q40459823
Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.Q40528997
Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cellsQ40855515
Polarized monolayers formed by epithelial cells on a permeable and translucent supportQ41233493
Quick-freeze, deep-etch visualization of the cytoskeleton beneath surface differentiations of intestinal epithelial cellsQ41367370
Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cellsQ41468891
Integrin expression and localization in normal MDCK cells and transformed MDCK cells lacking apical polarity.Q41492514
A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptideQ41498808
Regulation of the movement of solutes across tight junctionsQ41748263
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actinQ42459171
Planar polarization of the atypical myosin Dachs orients cell divisions in DrosophilaQ42573858
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.Q42953653
3D reconstruction of histological sections: Application to mammary gland tissueQ43627438
Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula OccludensQ43798217
Myosin II regulates the shape of three-dimensional intestinal epithelial cystsQ46609380
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
Tight junction formation in cultured epithelial cells (MDCK).Q54457086
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structureQ57179984
Hepatocyte Growth Factor Acutely Perturbs Actin Filament Anchorage at the Epithelial Zonula AdherensQ57728196
Actin at cell-cell junctions is composed of two dynamic and functional populationsQ63672364
Tube morphogenesisQ74644123
P4510describes a project that usesImageJQ1659584
P433issue9
P304page(s)1675-1687
P577publication date2012-03-14
P1433published inMolecular Biology of the CellQ2338259
P1476titleMyosin-X functions in polarized epithelial cells
P478volume23

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cites work (P2860)
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Q35964174Myosin X regulates neuronal radial migration through interacting with N-cadherin
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Q26825835Myosin-X and disease
Q30581595Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spread
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Q61444640Phenotypic analysis of Myo10 knockout (Myo10) mice lacking full-length (motorized) but not brain-specific headless myosin X
Q37221477Revisiting Myosin Families Through Large-scale Sequence Searches Leads to the Discovery of New Myosins
Q39242330Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division.
Q87954480The human cathelicidin LL-37 host defense peptide upregulates tight junction-related proteins and increases human epidermal keratinocyte barrier function