Regulation of the movement of solutes across tight junctions

scientific article published on January 1998

Regulation of the movement of solutes across tight junctions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV.PHYSIOL.60.1.143
P698PubMed publication ID9558458

P2093author name stringMadara JL
P304page(s)143-159
P577publication date1998-01-01
P1433published inAnnual Review of PhysiologyQ567364
P1476titleRegulation of the movement of solutes across tight junctions
P478volume60

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cites work (P2860)
Q35980854A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis
Q30583837A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayers
Q64887581A microfluidic model of human brain (μHuB) for assessment of blood brain barrier.
Q33247000A novel tool to characterize paracellular transport: the APTS-dextran ladder
Q47584716A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells
Q33292672A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions
Q92794083ABC efflux transporters at blood-central nervous system barriers and their implications for treating spinal cord disorders
Q39588905Actin cytoskeleton role in the structural response of epithelial (MDCK) cells to low extracellular Ca2+.
Q42169093Activation of extracellular regulated kinases is required for the increase in airway epithelial permeability during leukocyte transmigration
Q37046775Acute effects of short-chain alkylglycerols on blood-brain barrier properties of cultured brain endothelial cells.
Q95270406Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors
Q38235506Advances in oral macromolecular drug delivery
Q34004746Afa/Dr diffusely adhering Escherichia coli C1845 infection promotes selective injuries in the junctional domain of polarized human intestinal Caco-2/TC7 cells
Q42656327Altered gene expression in cerebral capillaries of stroke-prone spontaneously hypertensive rats
Q34691888Ammonia production, excretion, toxicity, and defense in fish: a review
Q35890738Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens
Q36053132Antrum Mucosal Protein-18 Peptide Targets Tight Junctions to Protect and Heal Barrier Structure and Function in Models of Inflammatory Bowel Disease.
Q37714206Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells
Q49108715Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier
Q36314957Astrovirus increases epithelial barrier permeability independently of viral replication
Q35594445Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease
Q34270337Bin1 attenuation suppresses experimental colitis by enforcing intestinal barrier function
Q38853362Biology of the Sertoli Cell in the Fetal, Pubertal, and Adult Mammalian Testis
Q38696206Biphasic influence of Staphylococcus aureus on human epidermal tight junctions
Q26777279Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
Q37632407Challenges and advances in nanoparticle-based oral insulin delivery.
Q57109417Changes in the expression levels of tight junction components during reconstruction of tight junction from mucosal lesion by intestinal ischemia/reperfusion
Q33333563Changes produced by external radiation in parameters influencing intestinal permeability and microparticle uptake in vitro
Q38051015Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal?
Q51806899Chronic metabolic acidosis stimulated transcellular and solvent drag-induced calcium transport in the duodenum of female rats.
Q37725542Claudin expression in high-grade invasive ductal carcinoma of the breast: correlation with the molecular subtype
Q28287255Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study
Q46645578Claudin-based paracellular proton barrier in the stomach
Q42488651Claudins regulate the intestinal barrier in response to immune mediators
Q28212968Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha
Q33504574Clostridium perfringens epsilon toxin increases the small intestinal permeability in mice and rats
Q44970180Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers
Q24672615Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors
Q33701592Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism
Q39739247Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers
Q35865807Defences against ammonia toxicity in tropical air-breathing fishes exposed to high concentrations of environmental ammonia: a review
Q34902014Deoxynivalenol impairs hepatic and intestinal gene expression of selected oxidative stress, tight junction and inflammation proteins in broiler chickens, but addition of an adsorbing agent shifts the effects to the distal parts of the small intestin
Q35729154Development of immortalized rat conjunctival epithelial cell lines: an in vitro model to examine transepithelial antigen delivery
Q41436529Differential expression of claudin tight junction proteins in the human cortical nephron
Q61773593Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12
Q43506108Differential regulation of tight junction permeability during development of the retinal pigment epithelium
Q33841357Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex
Q24682136Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins
Q39714337Disruption of epithelial barrier integrity by Salmonella enterica serovar typhimurium requires geranylgeranylated proteins
Q39189861Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms
Q34148005Double gene deletion reveals lack of cooperation between claudin 11 and claudin 14 tight junction proteins.
Q39205763Drug discovery and regulatory considerations for improving in silico and in vitro predictions that use Caco-2 as a surrogate for human intestinal permeability measurements
Q37135563Dynamic purine signaling and metabolism during neutrophil-endothelial interactions
Q82313648Effect of a novel multipurpose contact lens solution on human corneal epithelial barrier function
Q42504208Effect of cholera toxin on passive transepithelial transport of 51Cr-ethylenediaminetetraacetic acid and 14C-mannitol in rat jejunum
Q33736548Effect of deoxynivalenol and other Type B trichothecenes on the intestine: a review
Q43042907Effect of electromagnetic field on endocytosis of cationic solid lipid nanoparticles by human brain-microvascular endothelial cells
Q42259565Effect of proinflammatory interleukins on jejunal nutrient transport
Q37682480Effects of aerobic exercise on lipid-effector molecules of the innate immune response
Q37375350Effects of soybean agglutinin on mechanical barrier function and tight junction protein expression in intestinal epithelial cells from piglets
Q34786013Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment
Q34409274Engineering of polarized tubular structures in a microfluidic device to study calcium phosphate stone formation
Q51369270Enhanced Oral Delivery of Bisphosphonate by Novel Absorption Enhancers: Improvement of Intestinal Absorption of Alendronate by N-Acyl Amino Acids and N-Acyl Taurates and Their Absorption-Enhancing Mechanisms.
Q42718449Enhancement of drug absorption through the blood-brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides.
Q40620861Epidermal Growth Factor Receptor Activation Differentially Regulates Claudin Expression and Enhances Transepithelial Resistance in Madin-Darby Canine Kidney Cells
Q34117779Establishment of an in vitro brain barrier epithelial transport system for pharmacological and toxicological study
Q46189163Estimate of the subepithelial hydrostatic pressure that drives inflammatory transudate into the airway lumen
Q40500275Ethanol increases the paracellular permeability of monolayers of CAPAN-1 pancreatic duct cells
Q40806595Etk/Bmx activation modulates barrier function in epithelial cells
Q39278921Europium complexes as novel indicators of paracellular diffusion
Q41614989Evidence for the Involvement of RhoA Signaling in the Ethanol-Induced Increase in Intestinal Epithelial Barrier Permeability
Q37215871Exploring tight junction alteration using double fluorescent probe combination of lanthanide complex with gold nanoclusters
Q39684300Expression of Claudin-2 in intestinal metaplastic mucosa of Cdx2-transgenic mouse stomach.
Q48031088Expression of occludin in human rectal carcinoid tumours as a possible marker for glandular differentiation
Q31113913Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model
Q34260814Fibronectin-facilitated invasion of T84 eukaryotic cells by Campylobacter jejuni occurs preferentially at the basolateral cell surface
Q44878257Fragilysin, the enterotoxin from Bacteroides fragilis, enhances the serum antibody response to antigen co-administered by the intranasal route
Q35150365Functional analysis of tight junctions
Q37080750Functional effectiveness of the blood-brain barrier to small water-soluble molecules in developing and adult opossum (Monodelphis domestica)
Q40794057Functional modeling of tight junctions in intestinal cell monolayers using polyethylene glycol oligomers
Q44428843Functional role of adenosine receptor subtypes in the regulation of blood-brain barrier permeability: possible implications for the design of synthetic adenosine derivatives
Q37783437Functions of Claudin Tight Junction Proteins and Their Complex Interactions in Various Physiological Systems
Q52536783Galactose transport inhibition by cytochalasin E in rat intestine in vitro.
Q45149497Gene expression profiles in rat intestine identify pathways for 1,25-dihydroxyvitamin D(3) stimulated calcium absorption and clarify its immunomodulatory properties
Q35154231Genetic analysis of genes related to tight junction function in the Korean population with non-syndromic hearing loss
Q46077153Glucocorticoid down-regulation of RhoA is required for the steroid-induced organization of the junctional complex and tight junction formation in rat mammary epithelial tumor cells
Q40019129Glucocorticoids increase VE-cadherin expression and cause cytoskeletal rearrangements in murine brain endothelial cEND cells
Q34304839Hyaluronan and layilin mediate loss of airway epithelial barrier function induced by cigarette smoke by decreasing E-cadherin
Q36369318Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
Q57179983IgG transport across mucosal barriers by neonatal Fc receptor for IgG and mucosal immunity
Q40792873Improving the selectivity of HAV-peptides in modulating E-cadherin-E-cadherin interactions in the intercellular junction of MDCK cell monolayers
Q40913549In vitro transepithelial drug transport by on-line measurement: cellular control of paracellular and transcellular transport
Q89975956In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation
Q40004097Increased basolateral sorting of carcinoembryonic antigen in a polarized colon carcinoma cell line after cholesterol depletion-Implications for treatment of inflammatory bowel disease
Q36631468Inflammatory bowel disease and the apical junctional complex
Q34371928Interaction of bacteria and bacterial toxins with intestinal epithelial cells
Q28139702Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin
Q44433329Interactions between endothelial cells and epithelial cells in a combined cell model of airway mucosa: effects on tight junction permeability
Q40790831Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctions
Q38481730Intestinal intraepithelial lymphocytes sustain the epithelial barrier function against Eimeria vermiformis infection
Q37647153Intestinal villous M cells: an antigen entry site in the mucosal epithelium
Q41744796Involvement of the helix-loop-helix protein Id-1 in the glucocorticoid regulation of tight junctions in mammary epithelial cells
Q73933474Iontophoresis-enhanced absorptive flux of polar molecules across intestinal tissue in vitro
Q79079253Junctional complex revisited by high‐resolution scanning electron microscopy
Q41849877Keratinocyte junctions and the epidermal barrier: how to make a skin-tight dress
Q33424095L. plantarum prevents enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells
Q40610671Leucokinin and the modulation of the shunt pathway in Malpighian tubules
Q84779796Loss of Claudin-15, but Not Claudin-2, Causes Na+ Deficiency and Glucose Malabsorption in Mouse Small Intestine
Q37130397Lymphocyte homing and its role in the pathogenesis of IBD.
Q52754261MOF@activated carbon: a new material for adsorption of aldicarb in biological systems.
Q40707982Maintenance of the epithelial barrier in a bronchial epithelial cell line is dependent on functional E-cadherin local to the tight junctions
Q34572139Man the barrier! Strategic defences in the intestinal mucosa
Q39671668Mechanical responses of single non-confluent epithelial cells to low extracellular calcium
Q51906247Mechanistic understanding of oral drug absorption enhancement of cromolyn sodium by an amino acid derivative.
Q30809823Microtubules regulate disassembly of epithelial apical junctions
Q34422518Minireview: Steroid/nuclear receptor-regulated dynamics of occluding and anchoring junctions
Q55055706Modeling and rescue of defective blood-brain barrier function of induced brain microvascular endothelial cells from childhood cerebral adrenoleukodystrophy patients.
Q47252155Modulation of Intestinal Epithelial Permeability in Differentiated Caco-2 Cells Exposed to Aflatoxin M1 and Ochratoxin A Individually or Collectively
Q40896655Molecular decipherment of Rho effector pathways regulating tight-junction permeability
Q28210051Multifunctional strands in tight junctions
Q30513859Myosin-X functions in polarized epithelial cells
Q44304821Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells
Q30391507Nanoparticles for oral delivery: targeted nanoparticles with peptidic ligands for oral protein delivery
Q24670040Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin
Q51397230Neural control of intestinal ion transport and paracellular permeability is altered by nutritional status.
Q35747165Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins
Q42096387Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis
Q73533349Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport
Q34486064Novel Colitis Immunotherapy Targets Bin1 and Improves Colon Cell Barrier Function.
Q24299350Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activity
Q40898868Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin
Q33999630Opposing effects of the angiopoietins on the thrombin-induced permeability of human pulmonary microvascular endothelial cells
Q40558305Oscillations of voltage and resistance in Malpighian tubules of Aedes aegypti.
Q37571326Paracellular Cl- permeability is regulated by WNK4 kinase: insight into normal physiology and hypertension
Q34600116Paracellular fluid transport by epithelia
Q41816894Passage of cell-penetrating peptides across a human epithelial cell layer in vitro
Q50116199Periscope, up! Monitoring microbes in the intestine
Q40619870Permeability characteristics of parental and clonal human intestinal Caco-2 cell lines differentiated in serum-supplemented and serum-free media
Q36166111Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.
Q37012935Poly(amido amine) dendrimers in oral delivery
Q33195763Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium
Q38199099Possible roles of LI-Cadherin in the formation and maintenance of the intestinal epithelial barrier
Q33389486Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells
Q38266101Proteins and peptides: The need to improve them as promising therapeutics for ulcerative colitis.
Q36370858Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung
Q28365900Regulated expression of claudin-4 decreases paracellular conductance through a selective decrease in sodium permeability
Q44508296Regulation of adherens junctions and epithelial paracellular permeability: a novel function for polyamines
Q38021500Regulation of epithelial proliferation by tight junction proteins
Q42488747Regulation of glucose transporters during development of the retinal pigment epithelium
Q51432430Regulation of paracellular absorption of cimetidine and 5-aminosalicylate in rat intestine.
Q78004420Regulation of the intestinal epithelial paracellular barrier
Q40832397Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms
Q42496777Relationship between permeability status of the blood-brain barrier and in vitro permeability coefficient of a drug
Q41700873Requirement for Ras and phosphatidylinositol 3-kinase signaling uncouples the glucocorticoid-induced junctional organization and transepithelial electrical resistance in mammary tumor cells
Q35849738Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE)
Q28534764Rk1, a ginsenoside, is a new blocker of vascular leakage acting through actin structure remodeling
Q34359173Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex
Q35187759Role of AMP-18 in oral mucositis
Q38862486Roles of Serine/Threonine Phosphatases in Low-Dose Endothelial Monocyte-Activating Polypeptide-II-Induced Opening of Blood-Tumor Barrier
Q46766045Roles of ZO-1, occludin, and actin in oxidant-induced barrier disruption
Q22001489SEMP1, a senescence-associated cDNA isolated from human mammary epithelial cells, is a member of an epithelial membrane protein superfamily
Q44896653Salmonella enterica serovar Typhimurium regulates intercellular junction proteins and facilitates transepithelial neutrophil and bacterial passage
Q39998597Selective decrease in paracellular conductance of tight junctions: role of the first extracellular domain of claudin-5.
Q35672399Selective glucocorticoid control of Rho kinase isoforms regulate cell-cell interactions
Q44528945Serum-derived factors weaken the barrier properties of cultured porcine brain capillary endothelial cells in vitro
Q34002866Shiga toxins 1 and 2 translocate differently across polarized intestinal epithelial cells
Q40178843Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.
Q34482900Sidestream smoke exposure increases the susceptibility of airway epithelia to adenoviral infection
Q39359239Signal mechanisms underlying low-dose endothelial monocyte-activating polypeptide-II-induced opening of the blood-tumor barrier
Q37305578Signaling to the apical membrane and to the paracellular pathway: changes in the cytosolic proteome of Aedes Malpighian tubules
Q36831206Skin hydration: a review on its molecular mechanisms
Q34136096Spectrin: the ghost in the machine
Q41854266Sphingosine-1-Phosphate Regulates the Expression of Adherens Junction Protein E-Cadherin and Enhances Intestinal Epithelial Cell Barrier Function
Q43600153Stimulation of non-sodium-dependent water, electrolyte, and glucose transport in rat small intestine by gum arabic
Q34585071Strategies for increasing drug delivery to the brain: focus on brain lymphoma
Q38125197Strategies to increase drug penetration in solid tumors
Q33914550Structural correlates of the transepithelial water transport
Q61451727The In Vitro Protective Role of Bovine Lactoferrin on Intestinal Epithelial Barrier
Q38134725The blood-brain barrier: an engineering perspective.
Q28218429The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions
Q42068888The claudin Megatrachea protein complex.
Q40744821The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line(1).
Q39338566The effect of various absorption enhancers on tight junction in the human intestinal Caco-2 cell line
Q80509891The evolution of multicellularity in animals as a shift in biological autonomy
Q37906815The gut: beyond immunology
Q28066693The microbiome: A key regulator of stress and neuroinflammation
Q38014991The role of biomarkers in evaluating human health concerns from fungal contaminants in food
Q33640010The role of cell adhesion molecules in ischemic acute renal failure
Q24299510The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial cells
Q35763162The suprabasal layer of corneal epithelial cells represents the major barrier site to the passive movement of small molecules and trafficking leukocytes
Q30175138The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression
Q28255715The transcription factor Snail downregulates the tight junction components independently of E-cadherin downregulation
Q34629278Tight junction defects in patients with atopic dermatitis.
Q34086502Tight junction, a platform for trafficking and signaling protein complexes
Q42576359Tight junction-related barrier contributes to the electrophysiological asymmetry across vocal fold epithelium
Q28145432Tight junctions of the blood-brain barrier
Q24292730Tight junctions of the blood-brain barrier: development, composition and regulation
Q36400271Tight junctions: molecular architecture and function
Q35549914Towards a quantitative theory of epidermal calcium profile formation in unwounded skin
Q33632862Transcellular uptake mechanisms of the intestinal epithelial barrier Part one.
Q43571875Translocation of ribosomal immunostimulant through an in vitro-reconstituted digestive barrier containing M-like cells
Q42135913Transport of Aflatoxin M(1) in Human Intestinal Caco-2/TC7 Cells.
Q81326881Trichomonas vaginalis perturbs the junctional complex in epithelial cells
Q50554366Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells.
Q33556272Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium
Q36523960Type I Interferon Response Limits Astrovirus Replication and Protects against Increased Barrier Permeability In Vitro and In Vivo
Q57435331Ultrastructural changes in the equine colonic mucosa after ischaemia and reperfusion
Q40851142Understanding tight junction clinical physiology at the molecular level
Q34105722Ups and downs of mucosal cellular immunity against protozoan parasites
Q38130285Uriniferous tubule: structural and functional organization
Q43759818Vaginal-cervical epithelial permeability decreases after menopause
Q43297260Vasoactive intestinal peptide ameliorates intestinal barrier disruption associated with Citrobacter rodentium-induced colitis
Q41602366Vasoactive intestinal peptide prevents PKCε-induced intestinal epithelial barrier disruption during EPEC infection.
Q38815133Water transport through the intestinal epithelial barrier under different osmotic conditions is dependent on LI-cadherin trans-interaction
Q48910034Wound healing: The power of the purse string
Q39642580Yersinia enterocolitica induces epithelial barrier dysfunction through regional tight junction changes in colonic HT-29/B6 cell monolayers
Q30157199ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton
Q80311375[Gastric permeability and Helicobacter pylori]
Q40240304aPKC-PAR complex dysfunction and tight junction disassembly in renal epithelial cells during ATP depletion
Q24548291claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing

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