Molecular decipherment of Rho effector pathways regulating tight-junction permeability

scientific article

Molecular decipherment of Rho effector pathways regulating tight-junction permeability is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/0264-6021:3460617
P932PMC publication ID1220893
P698PubMed publication ID10698687
P5875ResearchGate publication ID12616357

P2093author name stringFujita H
Aoki J
Katoh H
Negishi M
Yamaguchi Y
Hasegawa H
Yasui H
P2860cites workp140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilinQ24316148
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)Q24319737
Rho protein regulates tight junctions and perijunctional actin organization in polarized epitheliaQ24563849
Occludin: a novel integral membrane protein localizing at tight junctionsQ24657666
Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludinQ24682664
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinaseQ28117594
Identification of a putative target for Rho as the serine-threonine kinase protein kinase NQ28273890
Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domainQ28281838
The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRFQ28292490
The small GTPase Rho: cellular functions and signal transductionQ28294633
Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epitheliaQ28299935
Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase RhoQ28511023
Small GTP-binding proteins and the regulation of the actin cytoskeletonQ28586463
Cooperation between mDia1 and ROCK in Rho-induced actin reorganizationQ28587275
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)Q28609825
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertensionQ29614247
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein RhoQ29614250
Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor proteinQ36233880
Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cellsQ38612666
Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cellsQ40941485
Effector domain mutants of Rho dissociate cytoskeletal changes from nuclear signaling and cellular transformationQ41007143
Two isoforms of prostaglandin EP3 receptor exhibiting constitutive activity and agonist-dependent activity in Rho-mediated stress fiber formationQ41109106
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinaseQ41126637
Rho effectors and reorganization of actin cytoskeletonQ41554078
Tight junctions.Q41695880
Molecular architecture of tight junctionsQ41748256
Regulation of the movement of solutes across tight junctionsQ41748263
RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.Q42639509
Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cellsQ42796987
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranesQ42819347
A general method for introducing a series of mutations into cloned DNA using the polymerase chain reactionQ43919784
Asparagine residue in the rho gene product is the modification site for botulinum ADP-ribosyltransferase.Q44186823
Establishment of tight junctions between cells from different animal species and different sealing capacitiesQ44556091
Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction.Q53872589
In vitro binding assay for interactions of Rho and Rac with GTPase-activating proteins and effectorsQ71521868
Regulation of vascular endothelial barrier functionQ72761942
p160 RhoA-binding kinase ROKalpha induces neurite retractionQ74105700
P407language of work or nameEnglishQ1860
P304page(s)617-622
P577publication date2000-03-01
P1433published inBiochemical JournalQ864221
P1476titleMolecular decipherment of Rho effector pathways regulating tight-junction permeability
P478volume346 Pt 3

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cites work (P2860)
Q89554714A New Rho(d) Map to Diffuse Gastric Cancer
Q45753289Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro
Q41614989Evidence for the Involvement of RhoA Signaling in the Ethanol-Induced Increase in Intestinal Epithelial Barrier Permeability
Q36324231Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability
Q39568460MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells.
Q39281815NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.
Q39726620RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones
Q35064607Rho GTPases and spermatogenesis.
Q33878942S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.
Q44489012WF-536 inhibits metastatic invasion by enhancing the host cell barrier and inhibiting tumour cell motility
Q30157199ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton