| scholarly article | Q13442814 |
| P50 | author | Yuko Fukata | Q57136371 |
| P2093 | author name string | M Ito | |
| T Nakano | |||
| K Chihara | |||
| Y Matsuura | |||
| K Kaibuchi | |||
| M Amano | |||
| K Kimura | |||
| P433 | issue | 34 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 20246-20249 | |
| P577 | publication date | 1996-08-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase) | |
| P478 | volume | 271 |
| Q37400854 | -Back-to-back mechanisms drive actomyosin ring closure during Drosophila embryo cleavage |
| Q33676489 | 1α,25-Dihydroxyvitamin D3 Ameliorates Seawater Aspiration-Induced Lung Injury By Inhibiting The Translocation Of NF-κB and RhoA |
| Q34042089 | 1α,25-dihydroxyvitamin D3 ameliorates seawater aspiration-induced acute lung injury via NF-κB and RhoA/Rho kinase pathways |
| Q48520087 | 2014 Williams Harvey Lecture: importance of coronary vasomotion abnormalities-from bench to bedside |
| Q42810876 | 5-HT7 receptor is coupled to G alpha subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology. |
| Q89565682 | A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts |
| Q35534618 | A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination |
| Q44323461 | A chemokine, SDF-1, reduces the effectiveness of multiple axonal repellents and is required for normal axon pathfinding. |
| Q92410553 | A current view of G protein-coupled receptor - mediated signaling in pulmonary hypertension: finding opportunities for therapeutic intervention |
| Q24536219 | A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability |
| Q36324190 | A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows |
| Q36825307 | A focal adhesion protein-based mechanochemical checkpoint regulates cleft progression during branching morphogenesis |
| Q34635299 | A force-activated kinase in a catch smooth muscle |
| Q30443946 | A major role for the rho-associated coiled coil forming protein kinase in G-protein-mediated Ca2+ sensitization through inhibition of myosin phosphatase in rabbit trachea |
| Q43210664 | A method for measuring Rho kinase activity in tissues and cells |
| Q46642481 | A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation |
| Q28270433 | A molecular ruler regulates cytoskeletal remodelling by the Rho kinases |
| Q36119672 | A molecular switch that controls cell spreading and retraction |
| Q45156955 | A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts |
| Q24321771 | A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion |
| Q53641554 | A novel DRAK inhibitor, SC82510, promotes axon branching of adult sensory neurons in vitro. |
| Q40971493 | A novel inhibitory effect of oxazol-5-one compounds on ROCKII signaling in human coronary artery vascular smooth muscle cells. |
| Q63395609 | A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration |
| Q28293294 | A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration |
| Q35163454 | A role for LIM kinase in cancer invasion. |
| Q64234976 | A role for actomyosin contractility in Notch signaling |
| Q36066631 | A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation |
| Q40269638 | A role of LIM kinase 1/cofilin pathway in regulating endocytic trafficking of EGF receptor in human breast cancer cells |
| Q24324544 | A single class II myosin modulates T cell motility and stopping, but not synapse formation |
| Q30556991 | A spindle-independent cleavage pathway controls germ cell formation in Drosophila |
| Q30490503 | A subset of signal transduction pathways is required for hippocampal growth cone collapse induced by ephrin-A5. |
| Q30524460 | A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells |
| Q57987065 | A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton |
| Q30483797 | ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells |
| Q49037118 | AMA0428, A Potent Rock Inhibitor, Attenuates Early and Late Experimental Diabetic Retinopathy |
| Q41870410 | ARF1 mediates paxillin recruitment to focal adhesions and potentiates Rho-stimulated stress fiber formation in intact and permeabilized Swiss 3T3 fibroblasts |
| Q30560783 | ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion |
| Q33960616 | ARF6 is required for growth factor- and rac-mediated membrane ruffling in macrophages at a stage distal to rac membrane targeting |
| Q37901431 | Aberrant activation of cell cycle regulators, centrosome amplification, and mitotic defects |
| Q49603114 | Aberrant endoplasmic reticulum stress mediates coronary artery spasm through regulating MLCK/MLC2 pathway |
| Q36057251 | Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency |
| Q29616027 | Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner |
| Q37641884 | Actin dynamics and competition for myosin monomer govern the sequential amplification of myosin filaments |
| Q36319839 | Actin-Cytoskeleton- and Rock-Mediated INM Are Required for Photoreceptor Regeneration in the Adult Zebrafish Retina |
| Q38337990 | Activated ROCK II by-passes the requirement of the CDK2 activity for centrosome duplication and amplification. |
| Q37252197 | Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation |
| Q42809055 | Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases |
| Q28587227 | Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets |
| Q24555685 | Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes |
| Q34712138 | Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation |
| Q28182396 | Activation of focal adhesion kinase by protein kinase C epsilon in neonatal rat ventricular myocytes |
| Q33815232 | Activation of moesin and adducin by Rho-kinase downstream of Rho. |
| Q34502458 | Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation |
| Q40606405 | Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42. |
| Q35364326 | Activin B antagonizes RhoA signaling to stimulate mesenchymal morphology and invasiveness of clear cell renal cell carcinomas |
| Q39042699 | Actomyosin Pulsing in Tissue Integrity Maintenance during Morphogenesis |
| Q39439075 | Actomyosin contractility and collective migration: may the force be with you. |
| Q49888527 | Acute compressive stress activates RHO/ROCK-mediated cellular processes. |
| Q35085307 | Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition |
| Q33843980 | Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src |
| Q34813646 | Albumin causes increased myosin light chain kinase expression in astrocytes via p38 mitogen-activated protein kinase |
| Q28588987 | Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling |
| Q35042997 | Alteration of the [Ca(2+)](i)-force relationship during the vasorelaxation induced by a Ca(2+) channel blocker SR33805 in the porcine coronary artery |
| Q29614737 | Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism |
| Q30496678 | An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments |
| Q37160941 | An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation |
| Q53426774 | An essential part for Rho-associated kinase in the transcellular invasion of tumor cells. |
| Q36118275 | An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling |
| Q33960909 | An integrated mathematical model of thrombin-, histamine-and VEGF-mediated signalling in endothelial permeability |
| Q28267048 | Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7 |
| Q42136527 | Analysis of pulmonary vasodilator responses to SB-772077-B [4-(7-((3-amino-1-pyrrolidinyl)carbonyl)-1-ethyl-1H-imidazo(4,5-c)pyridin-2-yl)-1,2,5-oxadiazol-3-amine], a novel aminofurazan-based Rho kinase inhibitor |
| Q46438925 | Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat. |
| Q33994877 | Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat |
| Q34089336 | Analysis of the role of Ser1/Ser2/Thr9 phosphorylation on myosin II assembly and function in live cells |
| Q33637557 | Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17. |
| Q24558666 | Anillin binds nonmuscle myosin II and regulates the contractile ring |
| Q31793833 | Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway. |
| Q90028607 | Apical Constriction Reversal upon Mitotic Entry Underlies Different Morphogenetic Outcomes of Cell Division |
| Q47145373 | Apical Sarcomere-like Actomyosin Contracts Nonmuscle Drosophila Epithelial Cells |
| Q36274919 | Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation |
| Q24336074 | Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase |
| Q30437811 | Assembly of MYPT1 with protein phosphatase-1 in fibroblasts redirects localization and reorganizes the actin cytoskeleton |
| Q38298722 | Association of N-cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons |
| Q36289185 | Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase |
| Q33762694 | Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction |
| Q52626028 | Atorvastatin preserves the integrity of endothelial adherens junctions by inhibiting vascular endothelial cadherin tyrosine phosphorylation. |
| Q41891381 | Augmented acetylcholine-induced, Rho-mediated Ca2+ sensitization of bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats |
| Q34948243 | Aurora B but not rho/MLCK signaling is required for localization of diphosphorylated myosin II regulatory light chain to the midzone in cytokinesis |
| Q37398180 | Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program |
| Q34756550 | Axon specification in hippocampal neurons. |
| Q30581117 | Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats |
| Q36639706 | BMP signaling and spadetail regulate exit of muscle precursors from the zebrafish tailbud |
| Q40915834 | Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments |
| Q35546873 | Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia |
| Q33597380 | Bidirectional signaling between the cytoskeleton and integrins |
| Q45163168 | Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin. |
| Q39155541 | CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling |
| Q28583123 | CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2- and CCL20-mediated restitution of colonic epithelial cells |
| Q34362792 | CD44-mediated oncogenic signaling and cytoskeleton activation during mammary tumor progression |
| Q44178394 | CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate (IP3) receptor-mediated Ca2+ signaling during hyaluronan (HA)-induced endothelial cell migration |
| Q40157234 | CUTL1 promotes tumor cell migration by decreasing proteasome-mediated Src degradation. |
| Q35987292 | CXCL16/CXCR6 chemokine signaling mediates breast cancer progression by pERK1/2-dependent mechanisms |
| Q50972674 | CYP2J2 metabolites, epoxyeicosatrienoic acids, attenuate Ang II-induced cardiac fibrotic response by targeting Gα12/13. |
| Q34937802 | Ca2+-dependent and Ca2+-independent regulation of smooth muscle contraction |
| Q77928592 | Ca2+-independent myosin II phosphorylation and contraction in chicken embryo fibroblasts |
| Q42470494 | Ca2+-independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments |
| Q26772115 | Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles |
| Q39192621 | Calcium Signaling Is Dispensable for Receptor Regulation of Endothelial Barrier Function |
| Q30479241 | Calyculin A, an enhancer of myosin, speeds up anaphase chromosome movement |
| Q90429712 | Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin-Dependent Mechano-Adaptation |
| Q42282668 | Cancer-associated fibroblasts support vascular growth through mechanical force. |
| Q35063893 | Canonical Wnt/β-catenin signalling is essential for optic cup formation |
| Q28210013 | Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing |
| Q41818131 | Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling. |
| Q39745580 | Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. |
| Q28236067 | Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion |
| Q34219436 | Cdk5: A regulator of epithelial cell adhesion and migration |
| Q92354769 | Cell Adhesion-Mediated Actomyosin Assembly Regulates the Activity of Cubitus Interruptus for Hematopoietic Progenitor Maintenance in Drosophila |
| Q38200137 | Cell adhesion in the assembly of the Drosophila eye. |
| Q30528961 | Cell elongation is an adaptive response for clearing long chromatid arms from the cleavage plane |
| Q26766248 | Cell polarity signaling in the plasticity of cancer cell invasiveness |
| Q40525937 | Cell type-specific regulation of RhoA activity during cytokinesis. |
| Q90354953 | Cell-Cell Mechanical Communication in Cancer |
| Q50422141 | Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. |
| Q90351944 | Cellular Mechanotransduction: From Tension to Function |
| Q36801514 | Cellular and molecular mechanisms regulating vascular tone. Part 2: regulatory mechanisms modulating Ca2+ mobilization and/or myofilament Ca2+ sensitivity in vascular smooth muscle cells |
| Q41750971 | Cellular control lies in the balance of forces |
| Q26828436 | Cellular mechanisms of the 5-HT7 receptor-mediated signaling |
| Q40732491 | Cellular regulation of extension and retraction of pseudopod-like blebs produced by nanosecond pulsed electric field (nsPEF). |
| Q73483178 | Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis |
| Q44193337 | Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin |
| Q34294435 | Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression |
| Q42277204 | Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion |
| Q41912140 | Characterization of a modified ROCK2 protein that allows use of N6-ATP analogs for the identification of novel substrates |
| Q56929332 | Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle |
| Q36980301 | Chlamydia trachomatis inclusion membrane protein CT228 recruits elements of the myosin phosphatase pathway to regulate release mechanisms |
| Q42524589 | Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries |
| Q34205231 | Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II |
| Q22004169 | Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron |
| Q28511633 | Cloning and identification of MYPT3: a prenylatable myosin targetting subunit of protein phosphatase 1 |
| Q46538773 | Clostridium difficile toxin B inhibits carbachol-induced force and myosin light chain phosphorylation in guinea-pig smooth muscle: role of Rho proteins |
| Q42791222 | Co-operative Cdc42 and Rho signalling mediates ephrinB-triggered endothelial cell retraction |
| Q54977101 | Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer. |
| Q30410743 | Combover/CG10732, a novel PCP effector for Drosophila wing hair formation |
| Q36169057 | Comparison of gel contraction mediated by airway smooth muscle cells from patients with and without asthma. |
| Q35164094 | Complement protein C1q modulates neurite outgrowth in vitro and spinal cord axon regeneration in vivo |
| Q30500161 | Completion of the epithelial to mesenchymal transition in zebrafish mesoderm requires Spadetail |
| Q47294328 | Computational modeling of single-cell mechanics and cytoskeletal mechanobiology. |
| Q27309190 | Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling |
| Q33211372 | Concentric zones of active RhoA and Cdc42 around single cell wounds |
| Q40317926 | Conditional regulation of a ROCK-estrogen receptor fusion protein |
| Q58125192 | Constriction of Retinal Venules to Endothelin-1: Obligatory Roles of ETA Receptors, Extracellular Calcium Entry, and Rho Kinase |
| Q34822720 | Contact guidance mediated three-dimensional cell migration is regulated by Rho/ROCK-dependent matrix reorganization |
| Q37093088 | Contractile forces in tumor cell migration |
| Q42477560 | Contribution of Rho kinase to the early phase of the calcium-contraction coupling in airway smooth muscle. |
| Q38943440 | Control of cell mechanics by RhoA and calcium fluxes during epithelial scattering |
| Q37224610 | Controversial effect of ethanol irrespective of kinases inhibition on the agonist-dependant vasoconstriction |
| Q39310262 | Conventional myosins - unconventional functions. |
| Q27312331 | Convergence and extrusion are required for normal fusion of the mammalian secondary palate |
| Q41712584 | Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II |
| Q36323662 | Cortical recruitment of nonmuscle myosin II in early syncytial Drosophila embryos: its role in nuclear axial expansion and its regulation by Cdc2 activity |
| Q35610507 | Creutzfeldt-Jakob Disease Subtype-Specific Regional and Temporal Regulation of ADP Ribosylation Factor-1-Dependent Rho/MLC Pathway at Pre-Clinical Stage. |
| Q28584193 | Cross-species genome wide expression analysis during pluripotent cell determination in mouse and rat preimplantation embryos |
| Q28079482 | Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability |
| Q28083749 | Crosstalk between intracellular and extracellular signals regulating interneuron production, migration and integration into the cortex |
| Q27667345 | Crystal Structure of a Coiled-Coil Domain from Human ROCK I |
| Q27749065 | Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue |
| Q40538780 | Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells |
| Q39081937 | Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells |
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| Q28265340 | Cytokinesis: IQGAPs find a function |
| Q77565690 | Cytomechanics of cadherin-mediated cell-cell adhesion |
| Q42834991 | Cytoplasmic p21Cip1 Is Involved in Ras-induced Inhibition of the ROCK/LIMK/Cofilin Pathway |
| Q35212825 | Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injury |
| Q40804659 | Cytoskeletal organization in tropomyosin-mediated reversion of ras-transformation: Evidence for Rho kinase pathway |
| Q38342846 | Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase. |
| Q36921010 | Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migration |
| Q42721563 | Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex |
| Q89604987 | Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells |
| Q27015713 | Cytoskeleton responses in wound repair |
| Q34325742 | Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21(Cip1/Waf1) in phorbol 12-myristate-13- acetate-induced apoptotic cells |
| Q39863905 | Cytotoxic necrotizing factor 1 of Escherichia coli stimulates Rho/Rho-kinase-dependent myosin light-chain phosphorylation without inactivating myosin light-chain phosphatase in endothelial cells. |
| Q47997547 | DAP-kinase-mediated morphological changes are localization dependent and involve myosin-II phosphorylation |
| Q36999751 | DEK depletion negatively regulates Rho/ROCK/MLC pathway in non-small cell lung cancer |
| Q30555216 | DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner |
| Q36631116 | DRhoGEF2 and diaphanous regulate contractile force during segmental groove morphogenesis in the Drosophila embryo |
| Q34026048 | Deficiency in myosin light-chain phosphorylation causes cytokinesis failure and multipolarity in cancer cells |
| Q33354161 | Deleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma |
| Q30435838 | Dendritic Spines: Similarities with Protrusions and Adhesions in Migrating Cells |
| Q40635065 | Dependence of metastatic cancer cell invasion on MLCK-catalyzed phosphorylation of myosin regulatory light chain |
| Q77366776 | Dephosphorylation of distinct sites on the 20 kDa myosin light chain by smooth muscle myosin phosphatase |
| Q43953881 | Dephosphorylation of the two regulatory components of myosin phosphatase, MBS and CPI17. |
| Q46460957 | Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells |
| Q38070804 | Development of cranial placodes: insights from studies in chick |
| Q36312219 | Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism |
| Q42837177 | Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis |
| Q46820326 | Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle. |
| Q44725602 | Differential effects of Rho-kinase inhibition on artery wall mass and remodeling |
| Q54559073 | Differential effects of myosin light chain kinase inhibition on contractility, force development and myosin light chain 20 phosphorylation of rat cervical and thoracic duct lymphatics. |
| Q38979479 | Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development |
| Q33644883 | Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets |
| Q28660856 | Differential protein expression between chondrogenic differentiated MSCs, undifferentiated MSCs and adult chondrocytes derived from Oryctolagus cuniculus in vitro |
| Q54327581 | Direct effects of Rho-kinase inhibitor on pial microvessels in rabbits. |
| Q57468222 | Disassembly of dying cells in diverse organisms |
| Q38584194 | Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising Directions |
| Q36146900 | Disrupting tumour blood vessels |
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| Q44884877 | Distinct kinases are involved in contraction of cat esophageal and lower esophageal sphincter smooth muscles |
| Q27304686 | Distinct predictive performance of Rac1 and Cdc42 in cell migration |
| Q37073549 | Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment |
| Q33849349 | Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress |
| Q36322203 | Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. |
| Q36328730 | Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts. |
| Q24299983 | Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. |
| Q33519066 | Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activation |
| Q47070036 | Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. |
| Q36825104 | Drosophila Rho-kinase (DRok) is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis |
| Q36236204 | Drosophila non-muscle myosin II motor activity determines the rate of tissue folding |
| Q42454045 | Drosophila nonmuscle myosin II promotes the asymmetric segregation of cell fate determinants by cortical exclusion rather than active transport |
| Q35138607 | Dual regulation of tumor necrosis factor-α on myosin light chain phosphorylation in vascular smooth muscle |
| Q44526847 | Duroquinone reduction during passage through the pulmonary circulation |
| Q47072853 | Dynamic analysis of actin cable function during Drosophila dorsal closure |
| Q34731335 | Dynamic analysis of dorsal closure in Drosophila: from genetics to cell biology |
| Q27304907 | Dynamic myosin activation promotes collective morphology and migration by locally balancing oppositional forces from surrounding tissue. |
| Q30585886 | Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis |
| Q34314357 | Dynamic regulation of myosin light chain phosphorylation by Rho-kinase. |
| Q58022582 | Dynamics and segregation of cell–matrix adhesions in cultured fibroblasts |
| Q36741254 | ERK5 promotes Src-induced podosome formation by limiting Rho activation |
| Q28483464 | Echovirus 30 induced neuronal cell death through TRIO-RhoA signaling activation |
| Q41778338 | Effect of age on the role of Rho-kinase in short-term partial bladder outlet obstruction |
| Q98245650 | Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion |
| Q57942456 | Effect of an oxytocin receptor antagonist and rho kinase inhibitor on the [Ca++]i sensitivity of human myometrium |
| Q44758277 | Effect of changes in pH on wall tension in isolated rat pulmonary artery: role of the RhoA/Rho-kinase pathway. |
| Q54582461 | Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries. |
| Q40470063 | Effects of S1P on myoblastic cell contraction: possible involvement of Ca-independent mechanisms. |
| Q37133948 | Effects of Y27632 on aqueous humor outflow facility with changes in hydrodynamic pattern and morphology in human eyes |
| Q34178276 | Effects of bladder function by early tamsulosin treatment in a spinal cord injury rat model |
| Q46334349 | Effects of eupatilin on the contractility of corpus cavernosal smooth muscle through nitric oxide-independent pathways |
| Q46973009 | Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils |
| Q36256216 | Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity |
| Q39756694 | Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases |
| Q41539692 | Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats |
| Q40861227 | Effects of the regulatory light chain phosphorylation of myosin II on mitosis and cytokinesis of mammalian cells |
| Q37792813 | Endothelial contractile cytoskeleton and microvascular permeability |
| Q52577774 | Endothelial cytoskeletal reorganization in response to PAR1 stimulation is mediated by membrane rafts but not caveolae. |
| Q37125689 | Endothelial signaling in paracellular and transcellular leukocyte transmigration |
| Q49488230 | Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta |
| Q30499138 | Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. |
| Q54083851 | Enhanced Ca(2+) mobilization in airway smooth muscle contributes to airway hyperresponsiveness in an inbred strain of rat. |
| Q34389888 | Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients |
| Q35037341 | Enhanced contractility and myosin phosphorylation induced by Ca(2+)-independent MLCK activity in hypertensive rats |
| Q41852828 | Epac as a novel effector of airway smooth muscle relaxation |
| Q91942694 | Eph signaling controls mitotic spindle orientation and cell proliferation in neuroepithelial cells |
| Q48203883 | Eph/ephrin reverse signalling induces axonal retraction through RhoA/ROCK pathway. |
| Q24303555 | EphA4-mediated Rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells |
| Q48209163 | Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system. |
| Q28647593 | Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase |
| Q30438563 | Epidermal growth factor-induced contraction regulates paxillin phosphorylation to temporally separate traction generation from de-adhesion |
| Q37044485 | Epigenetic repression of ribosomal RNA transcription by ROCK-dependent aberrant cytoskeletal organization |
| Q34014510 | Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo |
| Q28386966 | Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response |
| Q54979521 | Essential Role of Linx/Islr2 in the Development of the Forebrain Anterior Commissure. |
| Q47070828 | Essential roles of myosin phosphatase in the maintenance of epithelial cell integrity of Drosophila imaginal disc cells |
| Q42741243 | Establishment of the Muscle-Tendon Junction During Thorax Morphogenesis in Drosophila Requires the Rho-Kinase |
| Q35949988 | Estradiol modulates myosin regulatory light chain phosphorylation and contractility in skeletal muscle of female mice |
| Q48917184 | Evidence for involvement of ROCK signaling in bradykinin-induced increase in murine blood-tumor barrier permeability |
| Q41614989 | Evidence for the Involvement of RhoA Signaling in the Ethanol-Induced Increase in Intestinal Epithelial Barrier Permeability |
| Q33917823 | Evidence that actomyosin cross bridges contribute to "passive" tension in detrusor smooth muscle |
| Q46763613 | Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism. |
| Q49923465 | Evolving Mechanisms of Vascular Smooth Muscle Contraction Highlight Key Targets in Vascular Disease |
| Q57284424 | Ex vivo induction of regulatory T cells from conventional CD4 T cells is sensitive to substrate rigidity |
| Q35918917 | Excessive Myosin activity in mbs mutants causes photoreceptor movement out of the Drosophila eye disc epithelium. |
| Q92540403 | Expansion and contraction of the umbrella cell apical junctional ring in response to bladder filling and voiding |
| Q91737519 | Expression And Biological Interaction Network Of RHOC For Hepatic Carcinoma With Metastasis In PBMC Samples |
| Q53631077 | Expression of RND proteins in human myometrium. |
| Q38784164 | Expression of Tau Produces Aberrant Plasma Membrane Blebbing in Glial Cells Through RhoA-ROCK-Dependent F-Actin Remodeling. |
| Q28565083 | Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells |
| Q27005889 | Extracellular and Intracellular Signaling for Neuronal Polarity |
| Q51601402 | Extracellular matrix-dependent myosin dynamics during G1-S phase cell cycle progression in hepatocytes. |
| Q24299646 | Extracellular signal-regulated kinase mediates phosphorylation of tropomyosin-1 to promote cytoskeleton remodeling in response to oxidative stress: impact on membrane blebbing |
| Q24307808 | FERM domain-containing protein FRMD5 regulates cell motility via binding to integrin β5 subunit and ROCK1 |
| Q34007808 | FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway. |
| Q57167650 | Factors promoting vulnerability to dysregulated stress reactivity and stress-related disease |
| Q30511954 | Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy |
| Q50356583 | Fasudil inhibits proliferation and migration of Hep-2 laryngeal carcinoma cells |
| Q48455528 | Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability |
| Q50605109 | Fibroblast elongation and dendritic extensions in constrained versus unconstrained microtissues. |
| Q41332164 | Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness |
| Q28565264 | Fibronectin matrix assembly requires distinct contributions from Rho kinases I and -II |
| Q42480091 | Fibronectin's central cell-binding domain supports focal adhesion formation and Rho signal transduction |
| Q36866626 | Fixed-combination and emerging glaucoma therapies |
| Q33654206 | Fluidization and resolidification of the human bladder smooth muscle cell in response to transient stretch |
| Q26777662 | Focal adhesions, stress fibers and mechanical tension |
| Q34130640 | Focal loss of actin bundles causes microtubule redistribution and growth cone turning |
| Q61816278 | Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism |
| Q38513409 | Force transmission in epithelial tissues |
| Q26824081 | From mechanical force to RhoA activation |
| Q40444671 | From the Cover: Investigative Nonclinical Cardiovascular Safety and Toxicology Studies with BMS-986094, an NS5b RNA-Dependent RNA Polymerase Inhibitor |
| Q40648177 | Functional diversity between Rho-kinase- and MLCK-mediated cytoskeletal actions in a myofibroblast-like hepatic stellate cell line. |
| Q28141120 | Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization |
| Q30481848 | GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA. |
| Q48172315 | GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. |
| Q47445704 | GRAF3 serves as a blood volume-sensitive rheostat to control smooth muscle contractility and blood pressure |
| Q43730420 | Galpha11 induces caspase-mediated proteolytic activation of Rho-associated kinase, ROCK-I, in HeLa cells |
| Q41094488 | Gap junction-mediated regulation of endothelial cellular stiffness |
| Q40547065 | Gene delivery of l-caldesmon protects cytoskeletal cell membrane integrity against adenovirus infection independently of myosin ATPase and actin assembly. |
| Q92838602 | Gene silencing NMII promotes axonal regeneration against contusive spinal cord injury in rats |
| Q34609955 | Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis |
| Q34537585 | Genetic evidence for antagonism between Pak protein kinase and Rho1 small GTPase signaling in regulation of the actin cytoskeleton during Drosophila oogenesis |
| Q34618981 | Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis. |
| Q38108312 | Genetics of cerebral vasospasm |
| Q60960109 | Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet |
| Q37714904 | Ginsenoside Rb1 protects against ischemia/reperfusion-induced myocardial injury via energy metabolism regulation mediated by RhoA signaling pathway |
| Q39634449 | Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway |
| Q39680987 | Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway. |
| Q49499717 | Go with the flow: GEF-H1 mediated shear stress mechanotransduction in neutrophils. |
| Q37843684 | Good fences make good neighbors: Gastrointestinal mucosal structure |
| Q40035659 | Green tea polyphenol epigallocatechin-3-gallate signaling pathway through 67-kDa laminin receptor. |
| Q95721239 | Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization |
| Q42074534 | Growth factor regulation of corneal keratocyte mechanical phenotypes in 3-D collagen matrices |
| Q57072959 | Guidance Molecules in Vascular Smooth Muscle |
| Q84618098 | Guidelines for Diagnosis and Treatment of Patients With Vasospastic Angina (Coronary Spastic Angina) (JCS 2008) - Digest Version - |
| Q35795892 | Guiding neuronal growth cones using Ca2+ signals. |
| Q33716082 | H-series protein kinase inhibitors and potential clinical applications |
| Q39496498 | HAb18G/CD147 promotes cell motility by regulating annexin II-activated RhoA and Rac1 signaling pathways in hepatocellular carcinoma cells |
| Q43823830 | HSP27 modulates agonist-induced association of translocated RhoA and PKC-alpha in muscle cells of the colon |
| Q34704104 | Helicobacter pylori CagA disrupts epithelial patterning by activating myosin light chain |
| Q34559070 | Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension |
| Q34764587 | Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures |
| Q58769737 | Hippocampal Memory Recovery After Acute Stress: A Behavioral, Morphological and Molecular Study |
| Q51787397 | Human embryonic stem cells: caught between a ROCK inhibitor and a hard place. |
| Q24608189 | Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion |
| Q37152303 | Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression |
| Q53121132 | Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition. |
| Q47952764 | Hypoxia inhibits myosin phosphatase in pulmonary arterial smooth muscle cells: role of Rho-kinase |
| Q24613508 | Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells |
| Q57099542 | Hypoxic pulmonary vasoconstriction |
| Q33906406 | INSIGHTS INTO THE ROLES OF NON-MUSCLE MYOSIN IIA IN HUMAN KERATINOCYTE MIGRATION |
| Q47072662 | Identification and characterization of Drosophila homolog of Rho-kinase |
| Q41899573 | Identification and localization of myosin phosphatase in human platelets |
| Q36544368 | Identification by mass spectrometry of the phosphorylated residue responsible for activation of the catalytic domain of myosin I heavy chain kinase, a member of the PAK/STE20 family |
| Q48048185 | Identification of MAPKAPK Homolog (MAPKAPK-4) as a Myosin II Regulatory Light-Chain Kinase in Sea Urchin Egg Extracts |
| Q35244374 | Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis |
| Q35313440 | Identification of a negative regulatory region for the exchange activity and characterization of T332I mutant of Rho guanine nucleotide exchange factor 10 (ARHGEF10). |
| Q30725655 | Identification of myosin II kinase from sea urchin eggs as protein kinase CK2. |
| Q34604496 | Impaired coronary microvascular dilation correlates with enhanced vascular smooth muscle MLC phosphorylation in diabetes |
| Q39012623 | Increase in cell motility by carbon ion irradiation via the Rho signaling pathway and its inhibition by the ROCK inhibitor Y-27632 in lung adenocarcinoma A549 cells |
| Q44327827 | Increased contractility of diabetic rabbit corpora smooth muscle in response to endothelin is mediated via Rho-kinase beta |
| Q28571878 | Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus |
| Q34047215 | Induction and regulation of epithelial-mesenchymal transitions |
| Q36631468 | Inflammatory bowel disease and the apical junctional complex |
| Q42805239 | Inhibition of ROCK by RhoE. |
| Q36873446 | Inhibition of Rho is required for cAMP-induced melanoma cell differentiation. |
| Q33948775 | Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells |
| Q46878637 | Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum |
| Q53960749 | Inhibition of Rho-associated kinase relieves C5a-induced proteinuria in murine nephrotic syndrome. |
| Q30663201 | Inhibition of Rho-associated kinases disturbs the collective cell migration of stratified TE-10 cells |
| Q37113619 | Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection. |
| Q40337335 | Inhibition of motile and invasive properties of ovarian cancer cells by ASODN against Rho-associated protein kinase |
| Q40184462 | Inhibition of zipper-interacting protein kinase function in smooth muscle by a myosin light chain kinase pseudosubstrate peptide |
| Q37673277 | Inhibitor κB kinase 2 is a myosin light chain kinase in vascular smooth muscle |
| Q43780882 | Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells |
| Q36482254 | Insights into the role of focal adhesion modulation in myogenic differentiation of human mesenchymal stem cells |
| Q38703874 | Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix. |
| Q34931636 | Integration of pathways that signal cardiac growth with modulation of myofilament activity |
| Q92142838 | Integrin Mechano-chemical Signaling Generates Plasma Membrane Nanodomains that Promote Cell Spreading |
| Q42579182 | Integrin-linked kinase controls vascular wall formation by negatively regulating Rho/ROCK-mediated vascular smooth muscle cell contraction |
| Q40679163 | Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle |
| Q37878251 | Integrin-linked kinase: not so 'pseudo' after all. |
| Q36256316 | Integrin-mediated signals regulated by members of the rho family of GTPases |
| Q92598539 | Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix |
| Q30437361 | Integrins in cell migration--the actin connection |
| Q73797127 | Interaction between Cdc42Hs and RhoGDI is mediated through the Rho insert region |
| Q24305428 | Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication |
| Q29618086 | Intestinal mucosal barrier function in health and disease |
| Q57040333 | Into the breach: how cells cope with wounds |
| Q36065090 | Intracellular Ascorbate Prevents Endothelial Barrier Permeabilization by Thrombin |
| Q46618409 | Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation. |
| Q89606197 | Intracellular signaling dynamics and their role in coordinating tissue repair |
| Q34085621 | Intracellular signaling events at the leading edge of migrating cells |
| Q38423864 | Intracellular signaling of cardiac fibroblasts |
| Q34773995 | Intracellular signalling involved in modulating human endothelial barrier function |
| Q34634197 | Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions |
| Q52774602 | Involvement of ARHGEF10, GEF for RhoA, in Rab6/Rab8-mediating membrane traffic. |
| Q50710653 | IpaA targets beta1 integrins and rho to promote actin cytoskeleton rearrangements necessary for Shigella entry. |
| Q41216543 | Ivabradine reduces chemokine-induced CD4-positive lymphocyte migration |
| Q41649077 | Kinase-interacting substrate screening is a novel method to identify kinase substrates |
| Q31068587 | LDL-induced impairment of human vascular smooth muscle cells repair function is reversed by HMG-CoA reductase inhibition |
| Q42019507 | LIM kinase and Diaphanous cooperate to regulate serum response factor and actin dynamics |
| Q33563355 | LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration |
| Q42113269 | LPA-induced mutually exclusive subcellular localization of active RhoA and Arp2 mRNA revealed by sequential FRET and FISH. |
| Q36579308 | Lactoferrin promotes collagen gel contractile activity of fibroblasts mediated by lipoprotein receptors |
| Q47632836 | Lidocaine induces ROCK-dependent membrane blebbing and subsequent cell death in rabbit articular chondrocytes |
| Q103029076 | Ligand-induced conformational rearrangements regulate the switch between membrane-proximal and distal functions of Rho kinase 2 |
| Q64889423 | Linking Cell Polarity to Cortical Development and Malformations. |
| Q44501125 | Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK. |
| Q35889323 | Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila. |
| Q22001485 | Localization of the gene coding for ROCK II/Rho kinase on human chromosome 2p24 |
| Q38810077 | Locally excitable Cdc42 signals steer cells during chemotaxis. |
| Q54577063 | Loss of contraction force in dermal fibroblasts with aging due to decreases in myosin light chain phosphorylation enzymes. |
| Q37054265 | Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility |
| Q92554849 | Loss of ϐPix Causes Defects in Early Embryonic Development, and Cell Spreading and PlateletDerived Growth Factor-Induced Chemotaxis in Mouse Embryonic Fibroblasts |
| Q37386811 | Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction |
| Q73195444 | Lysophosphatidic acid-induced platelet shape change proceeds via Rho/Rho kinase-mediated myosin light-chain and moesin phosphorylation |
| Q64067988 | MASP-1 Increases Endothelial Permeability |
| Q36633933 | MLCK-A, an unconventional myosin light chain kinase from Dictyostelium, is activated by a cGMP-dependent pathway |
| Q47129661 | MLCK-independent phosphorylation of MLC20 and its regulation by MAP kinase pathway in human bladder smooth muscle cells |
| Q37201734 | MURC deficiency in smooth muscle attenuates pulmonary hypertension |
| Q39857118 | Made to measure - keeping Rho kinase at a distance. |
| Q34413051 | Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression |
| Q43082460 | Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides |
| Q39429587 | Matrix compliance and RhoA direct the differentiation of mammary progenitor cells |
| Q36586254 | Matrix rigidity differentially regulates invadopodia activity through ROCK1 and ROCK2. |
| Q37038773 | Maximal stimulation-induced in situ myosin light chain kinase activity is upregulated in fetal compared with adult ovine carotid arteries |
| Q28087361 | Mechanical interactions and crosstalk between corneal keratocytes and the extracellular matrix |
| Q52584929 | Mechanical strain induced phospho-proteomic signaling in uterine smooth muscle cells. |
| Q35171103 | Mechanical tension drives cell membrane fusion |
| Q34049874 | Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane |
| Q27652622 | Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure |
| Q38491064 | Mechanisms of cell height changes that mediate epithelial invagination. |
| Q93231149 | Mechanisms of contractile ring tension production and constriction |
| Q46697023 | Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats |
| Q53988320 | Mechanisms of sodium fluoride-induced endothelial cell barrier dysfunction: role of MLC phosphorylation. |
| Q36787465 | Mechano-coupling and regulation of contractility by the vinculin tail domain |
| Q37214440 | Mechano-reciprocity is maintained between physiological boundaries by tuning signal flux through the Rho-associated protein kinase. |
| Q35877893 | Mechanobiology of tumor invasion: engineering meets oncology |
| Q36748725 | Mechanoregulation of gene expression in fibroblasts |
| Q34186278 | Mechanotransduction in development: a growing role for contractility |
| Q92732473 | Mechanotransduction: from the cell surface to the nucleus via RhoA |
| Q36472971 | Melanoma-expressed CD70 is involved in invasion and metastasis. |
| Q33941102 | Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. |
| Q27305351 | Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β |
| Q41699698 | Metabolic Stress-Induced Activation of AMPK and Inhibition of Constitutive Phosphoproteins Controlling Smooth Muscle Contraction: Evidence for Smooth Muscle Fatigue? |
| Q38106675 | Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors. |
| Q38786730 | Mice lacking myosin IXb, an inflammatory bowel disease susceptibility gene, have impaired intestinal barrier function and superficial ulceration in the ileum |
| Q64055458 | MicroRNA-92a promotes vascular smooth muscle cell proliferation and migration through the ROCK/MLCK signalling pathway |
| Q35922924 | Microenvironmental control of the breast cancer cell cycle |
| Q30480680 | Microtubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture |
| Q30581023 | Microtubule-dependent transport of vimentin filament precursors is regulated by actin and by the concerted action of Rho- and p21-activated kinases |
| Q92947057 | Microtubules promote intercellular contractile force transmission during tissue folding |
| Q33828559 | Migrastatics-Anti-metastatic and Anti-invasion Drugs: Promises and Challenges. |
| Q73387598 | Mildly oxidised low density lipoprotein induces platelet shape change via Rho-kinase-dependent phosphorylation of myosin light chain and moesin |
| Q89344744 | Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension |
| Q46307154 | Models of convergent extension during morphogenesis |
| Q39085737 | Modes of invasion during tumour dissemination. |
| Q41421660 | Modulation of HSP27 alters hypoxia-induced endothelial permeability and related signaling pathways |
| Q47584927 | Modulation of microenvironment for controlling the fate of periodontal ligament cells: the role of Rho/ROCK signaling and cytoskeletal dynamics |
| Q40896655 | Molecular decipherment of Rho effector pathways regulating tight-junction permeability |
| Q42796987 | Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells |
| Q33536501 | Molecular mechanisms of nonmuscle myosin-II regulation |
| Q42078834 | More than a feeling: discovering, understanding, and influencing mechanosensing pathways |
| Q36961186 | Morphogenic signaling in neurons via neurotransmitter receptors and small GTPases |
| Q52625063 | Multi-layered hypertrophied MEE formation by microtubule disruption via GEF-H1/RhoA/ROCK signaling pathway. |
| Q92370258 | Multiple feedback mechanisms fine-tune Rho signaling to regulate morphogenetic outcomes |
| Q36513354 | Multiple mechanisms involved in oxytocin-induced modulation of myometrial contractility |
| Q40295965 | Multiple signaling pathways mediate compaction of collagen matrices by EGF-stimulated fibroblasts |
| Q34588005 | Mutational analysis of Stubble-stubbloid gene structure and function in Drosophila leg and bristle morphogenesis |
| Q36322042 | Mutations in sticky lead to defective organization of the contractile ring during cytokinesis and are enhanced by Rho and suppressed by Rac |
| Q28216468 | Myofibroblasts and mechano-regulation of connective tissue remodelling |
| Q30476214 | Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts |
| Q30486472 | Myosin 2 maintains an open exocytic fusion pore in secretory epithelial cells |
| Q80764458 | Myosin II and Rho kinase activity are required for melanosome aggregation in fish retinal pigment epithelial cells |
| Q35033655 | Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature |
| Q30515379 | Myosin II is a negative regulator of oligodendrocyte morphological differentiation |
| Q37200935 | Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. |
| Q48517897 | Myosin II-interacting guanine nucleotide exchange factor (MYOGEF) promotes bleb retraction via stimulating cortex reassembly at the bleb membrane |
| Q41230047 | Myosin activity drives actomyosin bundle formation and organization in contractile cells of the Caenorhabditis elegans spermatheca |
| Q38364920 | Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption |
| Q28366077 | Myosin ii light chain phosphorylation regulates membrane localization and apoptotic signaling of tumor necrosis factor receptor-1 |
| Q37235310 | Myosin light chain kinase (MLCK) gene disruption in Dictyostelium: a role for MLCK-A in cytokinesis and evidence for multiple MLCKs |
| Q30591181 | Myosin light chain kinase (MLCK) regulates cell migration in a myosin regulatory light chain phosphorylation-independent mechanism. |
| Q46419793 | Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer |
| Q30304130 | Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner |
| Q33954983 | Myosin light chain kinase in microvascular endothelial barrier function |
| Q73401434 | Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro |
| Q30492985 | Myosin light chain kinase mediates transcellular intravasation of breast cancer cells through the underlying endothelial cells: a three-dimensional FRET study |
| Q37852278 | Myosin light chain kinases and phosphatase in mitosis and cytokinesis |
| Q28274342 | Myosin light chain phosphatase: subunit composition, interactions and regulation |
| Q39908010 | Myosin light chains are not a physiological substrate of AMPK in the control of cell structure changes |
| Q39734290 | Myosin motors and not actin comets are mediators of the actin-based Golgi-to-endoplasmic reticulum protein transport |
| Q36194972 | Myosin phosphatase Fine-tunes Zebrafish Motoneuron Position during Axonogenesis |
| Q28260078 | Myosin phosphatase: structure, regulation and function |
| Q50287494 | Myosin regulatory light chain phosphorylation by ROCK |
| Q40604620 | Myosin-mediated cytoskeleton contraction and Rho GTPases regulate laminin-5 matrix assembly |
| Q33866577 | Myosins: a diverse superfamily |
| Q24317262 | Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization |
| Q45170189 | N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase. |
| Q36586279 | N-cadherin signaling in synapse formation and neuronal physiology |
| Q57801150 | N-terminal acetylation and methylation differentially affect the function of MYL9 |
| Q39281815 | NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway. |
| Q37687440 | NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction |
| Q33563090 | Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation. |
| Q30544951 | Nephrons require Rho-kinase for proximal-distal polarity development |
| Q52977344 | Neurite outgrowth resistance to rho kinase inhibitors in PC12 Adh cell. |
| Q30486884 | Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism |
| Q34759983 | Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family |
| Q43465628 | Neuronal responses to myelin are mediated by rho kinase |
| Q31104433 | New insights into the structure-function relationships of Rho-associated kinase: a thermodynamic and hydrodynamic study of the dimer-to-monomer transition and its kinetic implications |
| Q37676375 | Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module |
| Q28567180 | Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1 |
| Q26778962 | Non-muscle myosin II in disease: mechanisms and therapeutic opportunities |
| Q26771368 | Novel Insights into the Roles of Rho Kinase in Cancer |
| Q33422883 | Novel anti-metastatic action of cidofovir mediated by inhibition of E6/E7, CXCR4 and Rho/ROCK signaling in HPV tumor cells. |
| Q38165311 | Novel contributions of the smoothelin-like 1 protein in vascular smooth muscle contraction and its potential involvement in myogenic tone |
| Q30480993 | Novel functions of Ect2 in polar lamellipodia formation and polarity maintenance during "contractile ring-independent" cytokinesis in adherent cells. |
| Q36183689 | Novel role of stathmin in microtubule-dependent control of endothelial permeability |
| Q37671297 | Novel vasocontractile role of the P2Y₁₄ receptor: characterization of its signalling in porcine isolated pancreatic arteries. |
| Q24312395 | Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase |
| Q24310615 | Nuclear myosin II regulates the assembly of preinitiation complex for ICAM-1 gene transcription |
| Q37720173 | O-GlcNAcylation promotes migration and invasion in human ovarian cancer cells via the RhoA/ROCK/MLC pathway |
| Q48150013 | Oligophrenin-1 Connects Exocytotic Fusion to Compensatory Endocytosis in Neuroendocrine Cells |
| Q30837755 | Omega-3 and omega-6 DPA equally inhibit the sphingosylphosphorylcholine-induced Ca2+-sensitization of vascular smooth muscle contraction via inhibiting Rho-kinase activation and translocation |
| Q38974336 | Opportunities to Target Specific Contractile Abnormalities with Smooth Muscle Protein Kinase Inhibitors |
| Q38590564 | Osteogenic growth peptide and its use as a bio-conjugate in regenerative medicine applications |
| Q91813983 | Ovarian Cancer Dissemination-A Cell Biologist's Perspective |
| Q34819599 | Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblasts |
| Q34063807 | Overlapping roles of Drosophila Drak and Rok kinases in epithelial tissue morphogenesis |
| Q30524150 | Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion |
| Q39652825 | P-cadherin counteracts myosin II-B function: implications in melanoma progression. |
| Q42126544 | PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity |
| Q30585894 | PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction. |
| Q46635191 | PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle |
| Q43712800 | PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction |
| Q28142927 | Pak to the future |
| Q42260007 | Par-1 controls myosin-II activity through myosin phosphatase to regulate border cell migration. |
| Q27641956 | Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase |
| Q28476345 | Peptide substrates for Rho-associated kinase 2 (Rho-kinase 2/ROCK2) |
| Q34439465 | Pericyte contractility controls endothelial cell cycle progression and sprouting: insights into angiogenic switch mechanics |
| Q90043911 | Pharmaco-Genetic Screen To Uncover Actin Regulators Targeted by Prostaglandins During Drosophila Oogenesis |
| Q93023408 | Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against β-amyloid |
| Q35920703 | Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1). |
| Q37312216 | Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion |
| Q34124216 | Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones |
| Q28579151 | Phosphorylation of CPI17 and myosin binding subunit of type 1 protein phosphatase by p21-activated kinase |
| Q28144017 | Phosphorylation of ERM proteins at filopodia induced by Cdc42 |
| Q24682432 | Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility |
| Q28144738 | Phosphorylation of collapsin response mediator protein-2 by Rho-kinase. Evidence for two separate signaling pathways for growth cone collapse |
| Q55478553 | Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase. |
| Q41884314 | Phosphorylation of myosin II regulatory light chain is necessary for migration of HeLa cells but not for localization of myosin II at the leading edge |
| Q40915136 | Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo |
| Q28647572 | Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK) |
| Q41827565 | Phosphorylation of the myosin phosphatase target subunit by integrin-linked kinase |
| Q24657236 | Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle |
| Q36392528 | Physiological role of ROCKs in the cardiovascular system |
| Q37613679 | Physiology of endothelin and the kidney |
| Q35095249 | Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis. |
| Q47071637 | Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe. |
| Q37998537 | Plasminogen activation and thrombolysis for ischemic stroke |
| Q33178933 | Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change |
| Q33875835 | Polarized Distribution of Active Myosin II Regulates Directional Migration of Cultured Olfactory Ensheathing Cells |
| Q27310174 | Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair |
| Q33669233 | Polyamines transduce the nongenomic, androgen-induced calcium sensitization in intestinal smooth muscle |
| Q57464815 | Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle |
| Q33953392 | Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts |
| Q41573058 | Potential Role of Microtubule Stabilizing Agents in Neurodevelopmental Disorders |
| Q33720590 | Potential drug targets: small GTPases that regulate leukocyte function |
| Q46889534 | Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta |
| Q30487678 | Profilin 1 is required for abscission during late cytokinesis of chondrocytes |
| Q42455440 | Prostaglandin E(2)-dependent blockade of actomyosin and stress fibre formation is mediated through S1379 phosphorylation of ROCK2. |
| Q27315815 | Protective effects of the mTOR inhibitor everolimus on cytoskeletal injury in human podocytes are mediated by RhoA signaling |
| Q33992775 | Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis |
| Q42182450 | Protein kinase C-dependent and Ca2+-dependent mechanisms of secretion from streptolysin O-permeabilized platelets: effects of leakage of cytosolic proteins |
| Q35180862 | Protein kinase network in the regulation of phosphorylation and dephosphorylation of smooth muscle myosin light chain |
| Q94532928 | Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration |
| Q30845159 | Protein phosphorylation regulates actomyosin-driven vesicle movement in cell extracts isolated from the green algae, Chara corallina |
| Q55143856 | Proteomic analysis of adipose tissue during the last weeks of gestation in pure and crossbred Large White or Meishan fetuses gestated by sows of either breed. |
| Q34038821 | Provocative testing for coronary reactivity and spasm |
| Q73089650 | Purification and in vitro activity of Rho-associated kinase |
| Q33302971 | Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy |
| Q30480625 | Quantitative assessment of local collagen matrix remodeling in 3-D culture: the role of Rho kinase |
| Q33326183 | Quantitative high-throughput cell-based assays for inhibitors of ROCK kinases |
| Q34260423 | RAC1 activation mediates Twist1-induced cancer cell migration |
| Q45318309 | RHO GTPase Effectors |
| Q45318310 | RHO GTPases Activate ROCKs |
| Q92876607 | ROCK Inhibition Drives Resolution of Acute Inflammation by Enhancing Neutrophil Apoptosis |
| Q35093634 | ROCK inhibition activates MCF-7 cells |
| Q34103656 | ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets |
| Q50931770 | ROCK inhibition produces anxiety-related behaviors in mice. |
| Q30408828 | ROCK inhibition promotes microtentacles that enhance reattachment of breast cancer cells |
| Q48351814 | ROCK inhibition with Y27632 activates astrocytes and increases their expression of neurite growth-inhibitory chondroitin sulfate proteoglycans |
| Q36122896 | ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice |
| Q36324827 | ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix |
| Q95831986 | ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism |
| Q27309510 | ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity |
| Q33375734 | ROCK1 and LIMK2 interact in spread but not blebbing cancer cells |
| Q30834307 | ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens |
| Q33706377 | ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability |
| Q41191433 | ROCK1 is a novel Rac1 effector to regulate tubular endocytic membrane formation during clathrin-independent endocytosis. |
| Q40299040 | ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation |
| Q46532614 | ROCKII Ser1366 phosphorylation reflects the activation status. |
| Q37953906 | ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration. |
| Q36124892 | ROCKs as therapeutic targets in cardiovascular diseases |
| Q42517938 | ROK contribution to endothelin-mediated contraction in aorta and mesenteric arteries following intermittent hypoxia/hypercapnia in rats |
| Q46280873 | ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS). |
| Q39329836 | Rab7b at the intersection of intracellular trafficking and cell migration. |
| Q40915141 | Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior |
| Q40918517 | Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading |
| Q44898329 | Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells |
| Q30499365 | Rac/Rho pathway regulates actin depolymerization induced by aminoglycoside antibiotics |
| Q57370872 | Rac1 and RhoA GTPases have antagonistic functions during N-cadherin-dependent cell-cell contact formation in C2C12 myoblasts |
| Q50740752 | Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. |
| Q28592646 | Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading |
| Q37294930 | Raf-1 levels determine the migration rate of primary endometrial stromal cells of patients with endometriosis |
| Q41887999 | Raf-1 regulates Rho signaling and cell migration |
| Q39567425 | Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and growth of melanoma cells |
| Q40658383 | Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis |
| Q30506257 | Reassessing the role and dynamics of nonmuscle myosin II during furrow formation in early Drosophila embryos |
| Q73148752 | Reciprocal interactions between cells and extracellular matrix during remodeling of tissue constructs |
| Q39174495 | Redox regulation of the actin cytoskeleton and its role in the vascular system |
| Q43755008 | Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase |
| Q61797822 | Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment |
| Q36000501 | Regulating filopodial dynamics through actin-depolymerizing factor/cofilin |
| Q34018448 | Regulation and expression of metazoan unconventional myosins |
| Q54082274 | Regulation of Ca2+-independent smooth muscle contraction by alternative staurosporine-sensitive kinase. |
| Q37828684 | Regulation of Cytoskeleton and Cell Adhesions by the Small GTPase Rho and Its Targets. |
| Q35931375 | Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues |
| Q40612950 | Regulation of MDCK cell-substratum adhesion by RhoA and myosin light chain kinase after ATP depletion |
| Q33772560 | Regulation of NADPH oxidase in vascular endothelium: the role of phospholipases, protein kinases, and cytoskeletal proteins |
| Q27006554 | Regulation of ROCK activity in cancer |
| Q38182134 | Regulation of RhoA activity by adhesion molecules and mechanotransduction |
| Q24322588 | Regulation of RhoA-dependent ROCKII activation by Shp2 |
| Q48000569 | Regulation of TNF-alpha-induced reorganization of the actin cytoskeleton and cell-cell junctions by Rho, Rac, and Cdc42 in human endothelial cells |
| Q36111557 | Regulation of adherens junction dynamics by phosphorylation switches. |
| Q35609851 | Regulation of blood pressure and salt homeostasis by endothelin |
| Q52542273 | Regulation of endothelial barrier function by the cAMP-dependent protein kinase. |
| Q36978333 | Regulation of focal adhesion kinase activation, breast cancer cell motility, and amoeboid invasion by the RhoA guanine nucleotide exchange factor Net1. |
| Q37726377 | Regulation of immune function by G protein-coupled receptors, trimeric G proteins, and RGS proteins. |
| Q33921474 | Regulation of intermediate filament organization during cytokinesis: possible roles of Rho-associated kinase |
| Q36853200 | Regulation of invadopodia by mechanical signaling |
| Q30478915 | Regulation of myosin II dynamics by phosphorylation and dephosphorylation of its light chain in epithelial cells |
| Q38963349 | Regulation of pulmonary endothelial barrier function by kinases |
| Q45065479 | Regulation of pulmonary venous tone in response to muscarinic receptor activation |
| Q37649264 | Regulation of smooth muscle contraction by small GTPases |
| Q34855952 | Regulation of somatic myosin activity by protein phosphatase 1β controls Drosophila oocyte polarization |
| Q36909557 | Regulation of the actin cytoskeleton by thrombin in human endothelial cells: role of Rho proteins in endothelial barrier function |
| Q41052407 | Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase |
| Q29620156 | Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton |
| Q37847669 | Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis |
| Q38924290 | Regulatory Roles of Fluctuation-Driven Mechanotransduction in Cell Function |
| Q74539426 | Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle |
| Q40669649 | Relaxation-expansion model for self-driven retinal morphogenesis: a hypothesis from the perspective of biosystems dynamics at the multi-cellular level |
| Q92099830 | Remote ischemic post-conditioning protects against myocardial ischemia/reperfusion injury by inhibiting the Rho-kinase signaling pathway |
| Q37397720 | Reprint of "The role of cytoskeleton in the regulation of vascular endothelial barrier function" [Microvascular Research 76 (2008) 202-207]. |
| Q57470987 | Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models |
| Q38162898 | Review of companies and drug classes in the 2007-2011 antihypertensive patent literature |
| Q34612747 | Rho GTPase signalling pathways in the morphological changes associated with apoptosis. |
| Q30448193 | Rho GTPase-dependent signaling is required for macrophage migration inhibitory factor-mediated expression of cyclin D1. |
| Q34443037 | Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells |
| Q40623088 | Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites |
| Q35064607 | Rho GTPases and spermatogenesis. |
| Q29547740 | Rho GTPases and their effector proteins |
| Q53423587 | Rho GTPases are over-expressed in human tumors. |
| Q37860720 | Rho GTPases as regulators of morphological neuroplasticity |
| Q39241843 | Rho GTPases in ameloblast differentiation |
| Q38050708 | Rho GTPases in animal cell cytokinesis: an occupation by the one percent |
| Q28647606 | Rho GTPases in growth cone guidance |
| Q36624071 | Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters |
| Q29620432 | Rho GTPases in neuronal morphogenesis |
| Q54110980 | Rho Kinase (ROCK) collaborates with Pak to Regulate Actin Polymerization and Contraction in Airway Smooth Muscle. |
| Q52718506 | Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarinoma Invasion and Tumor Growth. |
| Q30497518 | Rho Kinase Regulation of Fibroblast Migratory Mechanics in Fibrillar Collagen Matrices |
| Q38260925 | Rho Kinase and Dopaminergic Degeneration: A Promising Therapeutic Target for Parkinson's Disease |
| Q38850635 | Rho Kinases and Cardiac Remodeling |
| Q40119156 | Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia. |
| Q28645748 | Rho and Rac take center stage |
| Q43651093 | Rho directs activation-associated changes in rat hepatic stellate cell morphology via regulation of the actin cytoskeleton |
| Q36897945 | Rho kinase (ROCK) inhibitors |
| Q24314744 | Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production |
| Q35352722 | Rho kinase as a therapeutic target in cardiovascular disease |
| Q36755421 | Rho kinase in the regulation of cell death and survival |
| Q51998298 | Rho kinase inhibitor Y27632 affects initial heart myofibrillogenesis in cultured chick blastoderm. |
| Q43209553 | Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells |
| Q80099166 | Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells |
| Q47717786 | Rho kinase regulates schwann cell myelination and formation of associated axonal domains. |
| Q30660037 | Rho kinase regulates the intracellular micromechanical response of adherent cells to rho activation |
| Q35994798 | Rho kinase signaling pathways during stretch in primary alveolar epithelia |
| Q41331100 | Rho kinase-2 activation in human endothelial cells drives lysophosphatidic acid-mediated expression of cell adhesion molecules via NF-kappaB p65. |
| Q40343774 | Rho kinases (ROCKs) in sepsis-induced acute lung injury |
| Q37450106 | Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil |
| Q81602815 | Rho kinases regulate endothelial invasion and migration during valvuloseptal endocardial cushion tissue formation |
| Q24323622 | Rho mediates endocytosis of epidermal growth factor receptor through phosphorylation of endophilin A1 by Rho-kinase |
| Q35974513 | Rho proteins, mental retardation and the neurobiological basis of intelligence |
| Q41542894 | Rho proteins: targets for bacterial toxins |
| Q37687727 | Rho signaling and tight junction functions |
| Q51889127 | Rho signaling pathway and apical constriction in the early lens placode. |
| Q41184119 | Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases |
| Q91775757 | Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation |
| Q41329130 | Rho-Associated Kinases and Non-muscle Myosin IIs Inhibit the Differentiation of Human iPSCs to Pancreatic Endoderm |
| Q30502216 | Rho-Kinase Directs Bazooka/Par-3 Planar Polarity during Drosophila Axis Elongation |
| Q42501327 | Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways |
| Q39488840 | Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells. |
| Q34133985 | Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells |
| Q33968841 | Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions |
| Q36481811 | Rho-associated coiled-coil kinase (ROCK) protein controls microtubule dynamics in a novel signaling pathway that regulates cell migration |
| Q38100279 | Rho-associated coiled-coil kinase (ROCK) signaling and disease |
| Q34823543 | Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease |
| Q36703612 | Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis |
| Q36078205 | Rho-associated kinase 2 polymorphism of vasospastic angina in korean population |
| Q91959468 | Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells |
| Q28295444 | Rho-associated kinase of chicken gizzard smooth muscle |
| Q37786442 | Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions |
| Q39583935 | Rho-dependent agonist-induced spatio-temporal change in myosin phosphorylation in smooth muscle cells |
| Q52096698 | Rho-dependent contractile responses in the neuronal growth cone are independent of classical peripheral retrograde actin flow. |
| Q38612581 | Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22. |
| Q37891679 | Rho-guanine nucleotide exchange factors during development: Force is nothing without control |
| Q78049861 | Rho-kinase (ROK) promotes CD44v(3,8-10)-ankyrin interaction and tumor cell migration in metastatic breast cancer cells |
| Q43802280 | Rho-kinase activation is involved in hypoxia-induced pulmonary vasoconstriction |
| Q40708723 | Rho-kinase and myosin-II control phagocytic cup formation during CR, but not FcgammaR, phagocytosis |
| Q44107653 | Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells |
| Q24685128 | Rho-kinase controls cell shape changes during cytokinesis |
| Q40126648 | Rho-kinase dependent organization of stress fibers and focal adhesions in cultured fibroblasts. |
| Q34893701 | Rho-kinase in development and heart failure: insights from genetic models |
| Q74589506 | Rho-kinase in human neutrophils: a role in signalling for myosin light chain phosphorylation and cell migration |
| Q37138832 | Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter |
| Q28264544 | Rho-kinase inhibitors as therapeutics: from pan inhibition to isoform selectivity |
| Q35370325 | Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells |
| Q24678197 | Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association |
| Q40775912 | Rho-kinase regulates myosin II activation in MDCK cells during recovery after ATP depletion |
| Q33252503 | Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development |
| Q28609762 | Rho-kinase--mediated contraction of isolated stress fibers |
| Q33663771 | Rho-kinase-mediated Ca2+-independent contraction in rat embryo fibroblasts |
| Q33930464 | Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow. |
| Q43134390 | Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction |
| Q37881804 | Rho-kinase: important new therapeutic target in cardiovascular diseases |
| Q38129373 | Rho-kinase: regulation, (dys)function, and inhibition |
| Q36945360 | Rho-stimulated contractility contributes to the fibroblastic phenotype of Ras-transformed epithelial cells |
| Q42823179 | Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy |
| Q34362144 | Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis |
| Q35949016 | Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions |
| Q45099267 | RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability |
| Q42639509 | RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. |
| Q34171845 | RhoA is required for cortical retraction and rigidity during mitotic cell rounding |
| Q34062480 | RhoA regulates calcium-independent periodic contractions of the cell cortex |
| Q39576430 | RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network |
| Q34252249 | RhoA-induced cytoskeletal tension controls adaptive cellular remodeling to mechanical signaling. |
| Q37091980 | RhoA-mediated MLC2 regulates actin dynamics for cytokinesis in meiosis |
| Q50477773 | RhoA/ROCK pathway activity is essential for the correct localization of the germ plasm mRNAs in zebrafish embryos. |
| Q34199993 | RhoA/Rho-kinase, vascular changes, and hypertension |
| Q34293372 | RhoA/Rho-kinase: a novel player in the regulation of penile erection |
| Q37636738 | RhoA/Rho-kinase: pathophysiologic and therapeutic implications in gastrointestinal smooth muscle tone and relaxation |
| Q33658160 | RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6. |
| Q39575625 | RhoE regulates actin cytoskeleton organization and cell migration. |
| Q37781319 | RhoGTPases and Rho-effectors in hepatocellular carcinoma metastasis: ROCK N' Rho move it |
| Q35045815 | Rho‐kinase inhibitor inhibits both myosin phosphorylation‐dependent and ‐independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery |
| Q24298069 | Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity |
| Q24303641 | Rocks: multifunctional kinases in cell behaviour |
| Q36710758 | Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication. |
| Q34274475 | Role of CRMP-2 in neuronal polarity. |
| Q35562739 | Role of Protease-activated Receptors in the Vascular System |
| Q38215424 | Role of Rho kinases in abnormal and normal hematopoiesis |
| Q40410714 | Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells |
| Q54584375 | Role of RhoA/ROCK signaling in endothelial-monocyte-activating polypeptide II opening of the blood-tumor barrier: role of RhoA/ROCK signaling in EMAP II opening of the BTB. |
| Q35083933 | Role of rho kinase in the functional and dysfunctional tonic smooth muscles |
| Q37428863 | Role of stress fibers and focal adhesions as a mediator for mechano-signal transduction in endothelial cells in situ |
| Q73066675 | Role of the N-terminal region of the regulatory light chain in the dephosphorylation of myosin by myosin light chain phosphatase |
| Q35709644 | Role of the cytoskeleton during leukocyte responses |
| Q43720111 | Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. |
| Q28364936 | Role of transglutaminase II in retinoic acid-induced activation of RhoA-associated kinase-2 |
| Q36887060 | Role of various kinases in muscarinic M3 receptor-mediated contraction of longitudinal muscle of rat colon |
| Q46863306 | Roles for Rho/ROCK and vinculin in parietal endoderm migration |
| Q39998835 | Roles of Necl-5/poliovirus receptor and Rho-associated kinase (ROCK) in the regulation of transformation of integrin alpha(V)beta(3)-based focal complexes into focal adhesions. |
| Q24682493 | Roles of Rho-associated kinase in cytokinesis; mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments |
| Q36673631 | S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis |
| Q57811399 | SB772077B, A New Rho Kinase Inhibitor Enhances Aqueous Humour Outflow Facility in Human Eyes |
| Q33648805 | STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry |
| Q36445367 | Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective. |
| Q42235621 | Seawater-drowning-induced acute lung injury: From molecular mechanisms to potential treatments |
| Q73889731 | Selective inhibition of collagen-induced arachidonic acid liberation by 1-(5-iodonaphthalene-1-sulphonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-7), a myosin light chain kinase inhibitor, in washed rabbit platelets |
| Q29616181 | Self-organizing optic-cup morphogenesis in three-dimensional culture |
| Q34242704 | Ser1333 phosphorylation indicates ROCKI activation |
| Q39175989 | Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination. |
| Q30234726 | Sex differences in cardiovascular disease - Impact on care and outcomes |
| Q34675234 | Shroom2 regulates contractility to control endothelial morphogenesis |
| Q30304611 | Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. |
| Q41790497 | Signal transduction pathway regulating prostaglandin EP3 receptor-induced neurite retraction: requirement for two different tyrosine kinases. |
| Q35873838 | Signaling pathways underlying eosinophil cell motility revealed by using caged peptides |
| Q37312315 | Signaling through Rho GTPase pathway as viable drug target |
| Q34168199 | Signalling and crosstalk of Rho GTPases in mediating axon guidance. |
| Q34057932 | Small G-protein networks: their crosstalk and signal cascades. |
| Q74230894 | Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells |
| Q47967575 | Small GTPase RhoD suppresses cell migration and cytokinesis. |
| Q81303651 | Smn depletion alters profilin II expression and leads to upregulation of the RhoA/ROCK pathway and defects in neuronal integrity |
| Q33668383 | Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle |
| Q28586097 | Smooth-muscle contraction without smooth-muscle myosin |
| Q35378307 | Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials |
| Q92661715 | Spatiotemporal Regulation of Rho GTPases in Neuronal Migration |
| Q77811817 | Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments |
| Q34033134 | Specific isoforms of drosophila shroom define spatial requirements for the induction of apical constriction |
| Q36254887 | Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells |
| Q24554294 | Specification of actin filament function and molecular composition by tropomyosin isoforms |
| Q38096841 | Sphingolipids in lung endothelial biology and regulation of vascular integrity |
| Q24671831 | Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement |
| Q52575439 | Stable expression of intracellular Notch suppresses v-Src-induced transformation in avian neural cells. |
| Q26776067 | Statins in Asthma: Potential Beneficial Effects and Limitations |
| Q40890101 | Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase. |
| Q39370524 | Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis |
| Q83338133 | Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity |
| Q36256190 | Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases |
| Q24301334 | Structural insights into the interaction of ROCKI with the switch regions of RhoA |
| Q27678438 | Structure of Shroom domain 2 reveals a three-segmented coiled-coil required for dimerization, Rock binding, and apical constriction |
| Q27680926 | Structure of a highly conserved domain of Rock1 required for Shroom-mediated regulation of cell morphology |
| Q39272424 | Structure of the Shroom-Rho Kinase Complex Reveals a Binding Interface with Monomeric Shroom That Regulates Cell Morphology and Stimulates Kinase Activity |
| Q30484812 | Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells. |
| Q47978419 | Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates |
| Q36816542 | Suppression of the Rho/Rho-kinase pathway and prevention of cerebral vasospasm by combination treatment with statin and fasudil after subarachnoid hemorrhage in rabbit. |
| Q44873838 | Sustained muscle contraction induced by agonists, growth factors, and Ca(2+) mediated by distinct PKC isozymes |
| Q44564952 | Synthesis and pharmacological study of Rho-kinase inhibitors: pharmacomodulations on the lead compound Fasudil |
| Q58587943 | TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10 |
| Q57559209 | Targeting cerebrovascular Rho-kinase in stroke |
| Q47355011 | Tension, contraction and tissue morphogenesis |
| Q39274901 | The Actin Cytoskeleton in SMA and ALS: How Does It Contribute to Motoneuron Degeneration? |
| Q30440328 | The C-terminal tail region of nonmuscle myosin II directs isoform-specific distribution in migrating cells |
| Q38008295 | The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines. |
| Q57462385 | The ERM family member Merlin is required for endometrial gland morphogenesis |
| Q26774795 | The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease |
| Q24652634 | The GTP binding proteins Gem and Rad are negative regulators of the Rho-Rho kinase pathway |
| Q35149334 | The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2. |
| Q33668166 | The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase! |
| Q38350096 | The Novel Rho GTPase-activating Protein Family Protein, Rga8, Provides a Potential Link between Cdc42/p21-activated Kinase and Rho Signaling Pathways in the Fission Yeast, Schizosaccharomyces pombe |
| Q28504703 | The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis |
| Q90051193 | The Physical Mechanisms of Drosophila Gastrulation: Mesoderm and Endoderm Invagination |
| Q35056143 | The RHOad less traveled: the myosin phosphorylation-independent path from Rho kinase to cell contraction. Focus on "Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation". |
| Q33614703 | The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus |
| Q47986063 | The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells. |
| Q36315901 | The Rap GTPase activator Drosophila PDZ-GEF regulates cell shape in epithelial migration and morphogenesis |
| Q50255148 | The Rho guanine exchange factor RHGF-2 acts through the Rho-binding kinase LET-502 to mediate embryonic elongation in C. elegans |
| Q43957399 | The Rho kinase inhibitor azaindole-1 has long-acting vasodilator activity in the pulmonary vascular bed of the intact chest rat. |
| Q36320914 | The Rho kinases I and II regulate different aspects of myosin II activity |
| Q27005980 | The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis |
| Q77315357 | The Rho-related protein Rnd1 inhibits Ca2+ sensitization of rat smooth muscle |
| Q33559599 | The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells. |
| Q28200945 | The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization |
| Q27314891 | The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility |
| Q35216552 | The Role of Thrombin and Cell Contractility in Regulating Clustering and Collective Migration of Corneal Fibroblasts in Different ECM Environments |
| Q36434923 | The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton |
| Q36528106 | The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42 |
| Q44420525 | The Site Where Newly Synthesized ATP Is Necessary for Tension Development in α-Toxin Permeabilized Preparations of Rat Proximal Colon |
| Q41478563 | The Yersinia protein kinase A is a host factor inducible RhoA/Rac-binding virulence factor |
| Q37170851 | The actin cytoskeleton in cancer cell motility |
| Q28543052 | The actomyosin machinery is required for Drosophila retinal lumen formation |
| Q44683576 | The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells |
| Q34576674 | The cytoskeleton and cell volume regulation |
| Q39034091 | The effect of Rho-associated kinase inhibition on the proteome pattern of dissociated human embryonic stem cells. |
| Q36685225 | The effect of including the C2 insert of nonmuscle myosin II-C on neuritogenesis |
| Q35568886 | The effects of knockdown of rho-associated kinase 1 and zipper-interacting protein kinase on gene expression and function in cultured human arterial smooth muscle cells |
| Q92022018 | The effects of oral administration of the novel muscarinic receptor antagonist DA-8010 on overactive bladder in rat with bladder outlet obstruction |
| Q38187336 | The emerging role of mTOR signalling in antibacterial immunity |
| Q30499201 | The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. |
| Q22008023 | The essential role of profilin in the assembly of actin for microspike formation |
| Q54564670 | The impact of Rho-kinase inhibitor, "Fasudil", intracoronary bolus administration to improve refractory coronary vasospasm. |
| Q36628790 | The inhibitory effect of eupatilin on the agonist-induced regulation of vascular contractility |
| Q39460559 | The insert region of RhoA is essential for Rho kinase activation and cellular transformation |
| Q42158161 | The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle |
| Q34670832 | The leukocyte cytoskeleton in cell migration and immune interactions |
| Q41678519 | The mechanism and control of cytokinesis |
| Q41777695 | The mechanism underlying the contractile effect of a chemotactic peptide, formyl-Met-Leu-Phe on the guinea-pig Taenia coli |
| Q37587029 | The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells. |
| Q47951201 | The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells |
| Q41691431 | The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo |
| Q26825105 | The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration |
| Q34501695 | The phosphorylation state of MRLC is polyamine dependent in intestinal epithelial cells |
| Q39869490 | The planar cell polarity pathway directs parietal endoderm migration |
| Q37942765 | The promise of inhibition of smooth muscle tone as a treatment for erectile dysfunction: where are we now? |
| Q37504826 | The protective role of MLCP-mediated ERM dephosphorylation in endotoxin-induced lung injury in vitro and in vivo |
| Q47326513 | The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ. |
| Q36814756 | The regulation of smooth muscle contractility by zipper-interacting protein kinase |
| Q35281262 | The role of Rho GTPase proteins in CNS neuronal migration |
| Q37832156 | The role of RhoA/Rho kinase pathway in endothelial dysfunction |
| Q36981292 | The role of cytoskeleton in the regulation of vascular endothelial barrier function |
| Q33622519 | The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review |
| Q58543979 | The role of integrin β1 in the heterogeneity of human embryonic stem cells culture |
| Q30482874 | The role of myosin II in glioma invasion of the brain |
| Q38717133 | The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers |
| Q37420016 | The role of the formin gene fhod-1 in C. elegans embryonic morphogenesis |
| Q36877329 | The role of the integrin LFA-1 in T-lymphocyte migration |
| Q36298301 | The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites |
| Q64121484 | The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly |
| Q39863613 | The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells |
| Q28505710 | The smooth muscle-selective RhoGAP GRAF3 is a critical regulator of vascular tone and hypertension |
| Q55340936 | The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats. |
| Q33772662 | The structural and mechanical complexity of cell-growth control |
| Q28279001 | The structure of dimeric ROCK I reveals the mechanism for ligand selectivity |
| Q36525640 | The tension mounts: stress fibers as force-generating mechanotransducers |
| Q30541086 | The tone of pulmonary smooth muscle: ROK and Rho music? |
| Q91287072 | The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration |
| Q35146603 | The ups and downs of Rho-kinase and penile erection: upstream regulators and downstream substrates of rho-kinase and their potential role in the erectile response |
| Q36756648 | The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts. |
| Q51167736 | The versatility of RhoA activities in neural differentiation. |
| Q47069469 | TheCaenorhabditis elegansnonmuscle myosin genesnmy-1andnmy-2function as redundant components of thelet-502/Rho-binding kinase andmel-11/myosin phosphatase pathway during embryonic morphogenesis |
| Q90529888 | Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms |
| Q28366906 | Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase |
| Q38629870 | Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways |
| Q37085734 | Timing is everything: Rac1 controls Net1A localization to regulate cell adhesion |
| Q91175753 | Tissue Fluidity Promotes Epithelial Wound Healing |
| Q42128424 | Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase |
| Q42819457 | Transformation mediated by RhoA requires activity of ROCK kinases |
| Q34441557 | Transgelin 2 participates in lovastatin-induced anti-angiogenic effects in endothelial cells through a phosphorylated myosin light chain-related mechanism |
| Q40698661 | Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells. |
| Q38144624 | Tubulin, actin and heterotrimeric G proteins: coordination of signaling and structure |
| Q24324864 | Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases |
| Q37008845 | Tumour targeting by microtubule-depolymerizing vascular disrupting agents |
| Q37801480 | Two Themes on the Assembly of the Drosophila Eye |
| Q50221540 | Two coffins and a funeral: early or late caspase activation determines two types of apoptosis induced by DNA damaging agents |
| Q27305022 | Two distinct myosin II populations coordinate ovulatory contraction of the myoepithelial sheath in the Caenorhabditis elegans somatic gonad |
| Q37071121 | Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway |
| Q47867509 | Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. |
| Q42834338 | Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase |
| Q41813846 | Uncoupling apical constriction from tissue invagination |
| Q42582162 | Unraveling the determinants of protrusion formation |
| Q50337065 | Up-regulation of myometrial RHO effector proteins (PKN1 and DIAPH1) and CPI-17 (PPP1R14A) phosphorylation in human pregnancy is associated with increased GTP-RHOA in spontaneous preterm labor |
| Q34381569 | Update on pulmonary edema: the role and regulation of endothelial barrier function |
| Q42834896 | Use and properties of ROCK-specific inhibitor Y-27632. |
| Q34272394 | Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain |
| Q37944602 | Vascular smooth muscle myosin light chain diphosphorylation: mechanism, function, and pathological implications |
| Q54561863 | Vasorelaxant effect of Cinnamomi ramulus ethanol extract via rho-kinase signaling pathway. |
| Q30529813 | Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells |
| Q34119907 | Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape |
| Q30553119 | Wounded cells drive rapid epidermal repair in the early Drosophila embryo |
| Q28200973 | XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC |
| Q22009929 | ZIP kinase identified as a novel myosin regulatory light chain kinase in HeLa cells |
| Q28588545 | ZIP kinase is responsible for the phosphorylation of myosin II and necessary for cell motility in mammalian fibroblasts |
| Q91145886 | ZIP kinase phosphorylated and activated by Rho kinase/ROCK contributes to cytokinesis in mammalian cultured cells |
| Q30157199 | ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton |
| Q30672001 | Zipper-interacting protein kinase induces Ca(2+)-free smooth muscle contraction via myosin light chain phosphorylation |
| Q48175937 | aPKC-mediated displacement and actomyosin-mediated retention polarize Miranda in Drosophila neuroblasts |
| Q39474004 | aPKCζ affects directed cell migration through the regulation of myosin light chain phosphorylation |
| Q42159586 | alpha1-Adrenoceptor-mediated phosphorylation of myosin in rat-tail arterial smooth muscle |
| Q38180763 | cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP). |
| Q34244951 | cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action |
| Q37386122 | eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases |
| Q30499352 | mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion |
| Q24315196 | p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA |
| Q33889306 | p160ROCK mediates RhoA activation of Na-H exchange |
| Q36256616 | p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts |
| Q35987694 | p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I |
| Q43821615 | p38 MAPK activation by TGF-beta1 increases MLC phosphorylation and endothelial monolayer permeability |
| Q34072697 | p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells |
| Q92355126 | p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration |
| Q38757132 | α-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling |
| Q35655628 | αE-catenin regulates cell-cell adhesion and membrane blebbing during zebrafish epiboly |
| Q35047466 | β-Arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration |
| Q47978916 | β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. |
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