The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton

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The Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CHOM.2012.09.011
P932PMC publication ID3510437
P698PubMed publication ID23159055
P5875ResearchGate publication ID233536421

P50authorPaul FreemontQ53150464
P2093author name stringMei Liu
Charlotte Odendall
John Poh
David W Holden
Andrew D Catling
Nathalie Rolhion
Douglas J Lamont
Andreas Förster
P2860cites workIdentification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1Q24596134
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Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitorsQ27653491
The MAPK signaling cascadeQ28292599
Nonmuscle myosin IIb is involved in the guidance of fibroblast migrationQ28513074
SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodellingQ28563583
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II familyQ28592899
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)Q28609825
Active and inactive protein kinases: structural basis for regulationQ29616320
A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosisQ30157714
Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective mannerQ30304130
MEK1 activation by PAK: a novel mechanismQ30441421
Dynamics of intracellular bacterial replication at the single cell level.Q30493738
Identification of a novel mitogen-activated protein kinase kinase activation domain recognized by the inhibitor PD 184352.Q31113651
Molecular characterization of a mammalian smooth muscle myosin light chain kinaseQ33283963
SpvC is a Salmonella effector with phosphothreonine lyase activity on host mitogen-activated protein kinasesQ33320330
Molecular mechanisms of nonmuscle myosin-II regulationQ33536501
Characterization of grvA, an antivirulence gene on the gifsy-2 phage in Salmonella enterica serovar typhimuriumQ33995341
Macrophage nitric oxide synthase associates with cortical actin but is not recruited to phagosomesQ34009419
Assembly and function of type III secretory systemsQ34052773
Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivoQ34469867
Salmonella maintains the integrity of its intracellular vacuole through the action of SifA.Q35114802
Targeting of Salmonella typhimurium to vesicles containing lysosomal membrane glycoproteins bypasses compartments with mannose 6-phosphate receptorsQ36235294
The MEK/ERK cascade: from signaling specificity to diverse functionsQ36656631
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.Q36710758
Salmonellae interplay with host cellsQ37008201
Leucine-responsive regulatory protein (Lrp) acts as a virulence repressor in Salmonella enterica serovar TyphimuriumQ37075381
Involvement of Salmonella pathogenicity island 2 in the up-regulation of interleukin-10 expression in macrophages: role of protein kinase A signal pathwayQ37116523
Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectorsQ37994160
The function of myosin and myosin light chain kinase phosphorylation in smooth muscleQ39494677
Salmonella enterica serovar Typhimurium response involved in attenuation of pathogen intracellular proliferationQ39522566
Activation of a RhoA/myosin II-dependent but Arp2/3 complex-independent pathway facilitates Salmonella invasion.Q39556866
Active ERK/MAP kinase is targeted to newly forming cell-matrix adhesions by integrin engagement and v-SrcQ39922817
Fusion between phagosomes, early and late endosomes: a role for actin in fusion between late, but not early endocytic organelles.Q40397311
Salmonella enterica serovar Typhimurium infection induces cyclooxygenase 2 expression in macrophages: involvement of Salmonella pathogenicity island 2.Q40423161
Domain movements in protein kinasesQ40504109
Microtubule motors control membrane dynamics of Salmonella-containing vacuolesQ40588868
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeletonQ40658475
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages.Q40669003
Macrophages inhibit Salmonella typhimurium replication through MEK/ERK kinase and phagocyte NADPH oxidase activitiesQ40753427
Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.Q41072512
The invasion-associated type III secretion system of Salmonella enterica serovar Typhimurium is necessary for intracellular proliferation and vacuole biogenesis in epithelial cells.Q41472950
Salmonella pathogenicity island 2-dependent expression of suppressor of cytokine signaling 3 in macrophagesQ41954125
The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cellsQ42008135
SCAMP3 is a component of the Salmonella-induced tubular network and reveals an interaction between bacterial effectors and post-Golgi trafficking.Q42170366
Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cellsQ42501977
ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxisQ42805578
SifA, a type III secreted effector of Salmonella typhimurium, directs Salmonella-induced filament (Sif) formation along microtubules.Q43993314
Analysis of the mechanisms of Salmonella-induced actin assembly during invasion of host cells and intracellular replicationQ44447381
Phosphorylation and activation of smooth muscle myosin light chain kinase by MAP kinase and cyclin-dependent kinase-1.Q49023739
Memorial: Emmanuelle Caron 1967-2009.Q49843738
Remodelling of the actin cytoskeleton is essential for replication of intravacuolar SalmonellaQ50114033
Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibitionQ50335943
Interdependent domains controlling the enzymatic activity of mitogen-activated protein kinase kinase 1.Q52198227
Myosin II is associated with Golgi membranes: identification of p200 as nonmuscle myosin II on Golgi-derived vesicles.Q52528123
Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex.Q55053004
Myosin IIA regulates cell motility and actomyosin–microtubule crosstalkQ58022519
Protein kinasesQ61640787
Selective inhibition of catalytic activity of smooth muscle myosin light chain kinaseQ70341558
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P304page(s)657-668
P577publication date2012-11-01
P1433published inCell Host & MicrobeQ5058153
P1476titleThe Salmonella kinase SteC targets the MAP kinase MEK to regulate the host actin cytoskeleton
P478volume12

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cites work (P2860)
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Q35620178The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway
Q60922200The Major RNA-Binding Protein ProQ Impacts Virulence Gene Expression in Salmonella enterica Serovar Typhimurium
Q39080527WASH-driven actin polymerization is required for efficient mycobacterial phagosome maturation arrest

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