ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation

scientific article published on 2 November 2015

ROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/TACG.S90215
P932PMC publication ID4636093
P698PubMed publication ID26586960

P2093author name stringYogendra Singh
M A Qadar Pasha
Priyanka Pandey
Ghulam Mohammad
P2860cites workThe genetic architecture of adaptations to high altitude in EthiopiaQ21563365
Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)Q24319737
Folding free energies of 5'-UTRs impact post-transcriptional regulation on a genomic scale in yeastQ24815888
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The structure of haplotype blocks in the human genomeQ27860500
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Interactions among vascular-tone modulators contribute to high altitude pulmonary edema and augmented vasoreactivity in highlandersQ28483668
c-Jun decreases voltage-gated K(+) channel activity in pulmonary artery smooth muscle cellsQ28573461
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)Q28609825
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High-altitude illnessQ57109395
Hypoxia activates jun-N-terminal kinase, extracellular signal-regulated protein kinase, and p38 kinase in pulmonary arteriesQ73149687
An intronic MYLK variant associated with inflammatory lung disease regulates promoter activity of the smooth muscle myosin light chain kinase isoformQ82125863
Sympathetic neural overactivity in healthy humans after prolonged exposure to hypobaric hypoxiaQ33426416
High-altitude illnessQ33431682
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Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cellsQ33818132
Acetyl-l-carnitine (ALCAR) prevents hypobaric hypoxia-induced spatial memory impairment through extracellular related kinase-mediated nuclear factor erythroid 2-related factor 2 phosphorylationQ34016707
Calmodulin and the regulation of smooth muscle contractionQ34315595
Hypoxic activation of adventitial fibroblasts: role in vascular remodelingQ35022227
Activation of JNK/c-Jun is required for the proliferation, survival, and angiogenesis induced by EET in pulmonary artery endothelial cellsQ35958442
Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFβ receptor-JNK1 signallingQ36104454
Physiological role of ROCKs in the cardiovascular systemQ36392528
Role of ion channels in acute and chronic responses of the pulmonary vasculature to hypoxiaQ36530890
Phosphorylation of myosin regulatory light chain by myosin light chain kinase, and muscle contractionQ37358773
Silent (synonymous) SNPs: should we care about them?Q37600712
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c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosisQ37684175
Gene polymorphisms and high-altitude pulmonary edema susceptibility: a 2011 updateQ38003079
Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in ratsQ42105103
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Reactive oxygen species stimulate central and peripheral sympathetic nervous system activityQ44995341
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P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P921main subjecthypoxiaQ105688
pulmonary edemaQ857667
high altitudeQ59775044
P304page(s)257-267
P577publication date2015-11-02
P1433published inThe Application of Clinical GeneticsQ15817525
P1476titleROCK2 and MYLK variants under hypobaric hypoxic environment of high altitude associate with high altitude pulmonary edema and adaptation
P478volume8