Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3.

scientific article published on 24 August 2001

Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M106724200
P698PubMed publication ID11522794

P50authorJohn OrlowskiQ67912494
P2093author name stringGrinstein S
Kaibuchi K
Kurashima K
Szászi K
P2860cites workActivation of protein kinase A acutely inhibits and phosphorylates Na/H exchanger NHE-3Q35765899
Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinaseQ36218877
A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pHQ37561464
Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situQ39251346
Acute regulation of Na+/H+ exchanger NHE3 by parathyroid hormone via NHE3 phosphorylation and dynamin-dependent endocytosisQ40871739
Acute inhibition of Na/H exchanger NHE-3 by cAMP. Role of protein kinase a and NHE-3 phosphoserines 552 and 605.Q40975237
cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalphaQ41014721
Subcellular redistribution is involved in acute regulation of the brush border Na+/H+ exchanger isoform 3 in human colon adenocarcinoma cell line Caco-2. Protein kinase C-mediated inhibition of the exchangerQ41043721
Formation of actin stress fibers and focal adhesions enhanced by Rho-kinaseQ41126637
Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1Q41283042
Na+/H+ exchangers of mammalian cells.Q41581776
Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanismsQ42446313
Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinaseQ42484860
Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.Q47724641
Cyclic AMP-induced shape changes of astrocytes are accompanied by rapid depolymerization of actinQ48892793
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase triggers acute morphological changes in thyroid epithelial cells.Q52488275
Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi networkQ24291060
NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrinQ24315976
Identification of a mitochondrial Na+/H+ exchangerQ24318319
cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory proteinQ24569613
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail associationQ24678197
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)Q28609825
The expanding family of eucaryotic Na(+)/H(+) exchangersQ33807152
Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observationsQ33889753
Regulation of the epithelial Na(+) /H(+) exchanger isoform by the cytoskeletonQ34110078
Na+/H+ exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localizationQ34119293
Stabilization of F-actin prevents cAMP-elicited Cl- secretion in T84 cellsQ34264344
P433issue44
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P1104number of pages8
P304page(s)40761-40768
P577publication date2001-08-24
P1433published inJournal of Biological ChemistryQ867727
P1476titleRole of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3
P478volume276

Reverse relations

cites work (P2860)
Q44633089A C-Terminal PDZ Motif in NHE3 Binds NHERF-1 and Enhances cAMP Inhibition of Sodium−Hydrogen Exchange
Q30420969A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.
Q46187912Actin cytoskeletal and functional studies of the proximal convoluted tubules after preservation.
Q36717682Actin cytoskeleton-dependent dynamics of the human serotonin1A receptor correlates with receptor signaling
Q35000919Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells
Q28219753Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton
Q24323099Coexpression of MAST205 inhibits the activity of Na+/H+ exchanger NHE3.
Q46321862Differential traffic of proximal tubule Na+ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes
Q28185218Diversity of the mammalian sodium/proton exchanger SLC9 gene family
Q40026907Ezrin promotes functional expression and parathyroid hormone-mediated regulation of the sodium-phosphate cotransporter 2a in LLC-PK1 cells
Q33818285Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis
Q57364667Mechanisms of Ion Transport Regulation by Microfilaments
Q45182655Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling
Q26823086Molecular mechanisms and regulation of urinary acidification
Q36059428NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.
Q51796458NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors.
Q44217777NKCC activity restores muscle water during hyperosmotic challenge independent of insulin, ERK, and p38 MAPK.
Q35086788Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells
Q28579273Regulation of the rat brain Na+ -driven Cl-/HCO3 - exchanger involves protein kinase A and a multiprotein signaling complex
Q40096439RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3.
Q34803046Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells
Q42833405Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif
Q44601450cAMP inhibition of murine intestinal Na/H exchange requires CFTR-mediated cell shrinkage of villus epithelium

Search more.