scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M512374200 |
P698 | PubMed publication ID | 16699172 |
P50 | author | Stefan Bonn | Q47152931 |
P2093 | author name string | Christine B Breitenlechner | |
Dirk Bossemeyer | |||
Michael Gassel | |||
Richard A Engh | |||
Saturnino Herrero | |||
Andrea Erlbruch | |||
Wolf Lehmann | |||
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Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity | Q27642704 | ||
Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity | Q27733449 | ||
Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential | Q27748804 | ||
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains | Q27860528 | ||
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction | Q27860958 | ||
Regulation and functions of Rho-associated kinase | Q28138022 | ||
The structure of dimeric ROCK I reveals the mechanism for ligand selectivity | Q28279001 | ||
Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase) | Q28609825 | ||
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension | Q29614247 | ||
Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling | Q29617453 | ||
Creation and characterization of a new, non-redundant fragment data bank | Q30428274 | ||
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Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells | Q34133985 | ||
The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. | Q34302668 | ||
The phosphorylation of proteins: a major mechanism for biological regulation. Fourteenth Sir Frederick Gowland Hopkins memorial lecture | Q34564853 | ||
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases | Q34684562 | ||
The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway | Q34792910 | ||
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Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. | Q40724768 | ||
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Anti-anginal effect of fasudil, a Rho-kinase inhibitor, in patients with stable effort angina: a multicenter study | Q44200627 | ||
Essential role of rho kinase in the Ca2+ sensitization of prostaglandin F(2alpha)-induced contraction of rabbit aortae | Q44300294 | ||
Identification of electrostatic interactions that determine the phosphorylation site specificity of the cAMP-dependent protein kinase | Q44364227 | ||
Structure-based optimization of novel azepane derivatives as PKB inhibitors | Q44784861 | ||
Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants | Q45212813 | ||
Non-proline cis peptide bonds in proteins. | Q52225116 | ||
Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit | Q67253716 | ||
Signal transduction and growth control in normal and cancer cells | Q72455779 | ||
Purification and in vitro activity of Rho-associated kinase | Q73089650 | ||
P433 | issue | 34 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 24818-24830 | |
P577 | publication date | 2006-05-12 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity | |
P478 | volume | 281 |
Q46642481 | A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation |
Q38552068 | Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases |
Q93137403 | Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity |
Q46273820 | Design and synthesis of potent and selective azaindole-based Rho kinase (ROCK) inhibitors |
Q91198095 | Diamondoid Amino Acid-Based Peptide Kinase A Inhibitor Analogues |
Q27667904 | Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors |
Q30363018 | Outliers in SAR and QSAR: 2. Is a flexible binding site a possible source of outliers? |
Q47675076 | PAK4 crystal structures suggest unusual kinase conformational movements |
Q33387038 | Prediction of specificity-determining residues for small-molecule kinase inhibitors |
Q37139305 | Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease |
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