Myosins in cell junctions

scientific article

Myosins in cell junctions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.4161/BIOA.21791
P932PMC publication ID3696060
P698PubMed publication ID22954512
P5875ResearchGate publication ID230809970

P50authorRichard CheneyQ42703433
P2093author name stringKaty C. Liu
P2860cites workThe localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulationQ22008538
Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cellsQ22008561
The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23Q22010266
Myosin VI is an actin-based motor that moves backwardsQ22010643
Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1DQ24290695
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell typesQ24313272
The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.Q24313482
Defective myosin VIIA gene responsible for Usher syndrome type 1BQ24314638
Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domainQ24323991
A novel gene for Usher syndrome type 2: mutations in the long isoform of whirlin are associated with retinitis pigmentosa and sensorineural hearing lossQ24337039
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundleQ24337137
Mutations of MYO6 are associated with recessive deafness, DFNB37Q24532041
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctionsQ35785344
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated miceQ35810540
Spindle position in symmetric cell divisions during epiboly is controlled by opposing and dynamic apicobasal forcesQ35903531
A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulationQ36066631
Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cellsQ36119767
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherensQ36191191
Mechanism of brush border contractility studied by the quick-freeze, deep-etch methodQ36208203
Myosin VI is a processive motor with a large step sizeQ24555089
Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1BQ24562934
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complexQ24597349
Deconstructing the cadherin-catenin-actin complexQ24609677
Regulation of cell-cell adhesion by the cadherin-catenin complexQ24609784
A millennial myosin censusQ24633678
Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosinQ24670442
Myosin XVA expression in the pituitary and in other neuroendocrine tissues and tumorsQ24685752
Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherensQ27330739
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargoQ27666702
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Rho GTPases: biochemistry and biologyQ27860645
Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2Q28115357
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenanceQ28155879
Myosin VI: two distinct roles in endocytosisQ28191412
A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctionsQ28211256
Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasionQ28236067
Non-muscle myosin II takes centre stage in cell adhesion and migrationQ28262326
Mechanism of blebbistatin inhibition of myosin IIQ28267628
Genetic variation in myosin IXB is associated with ulcerative colitisQ28272638
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defectQ28281383
Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomesQ28286152
Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1BQ28294301
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Q28504869
Disruption of Myosin 1e promotes podocyte injuryQ28509726
Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cellsQ28509764
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctionsQ28511375
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in miceQ28511656
Myosin-1a is critical for normal brush border structure and compositionQ28512472
A type VII myosin encoded by the mouse deafness gene shaker-1Q28512902
The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization.Q28513273
Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargosQ47070932
Myosin VI is required for structural integrity of the apical surface of sensory hair cells in zebrafishQ47073856
Unconventional myosin VIIa and vezatin, two proteins crucial for Listeria entry into epithelial cellsQ47748177
Myr 7 is a novel myosin IX-RhoGAP expressed in rat brainQ48348573
Expression of myosin VIIA during mouse embryogenesis.Q48647067
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
Identification and phylogenetic analysis of Drosophila melanogaster myosins.Q52597252
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
Cell adhesion molecule Echinoid associates with unconventional myosin VI/Jaguar motor to regulate cell morphology during dorsal closure in Drosophila.Q52684724
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structureQ57179984
Hepatocyte Growth Factor Acutely Perturbs Actin Filament Anchorage at the Epithelial Zonula AdherensQ57728196
Mechanical tugging force regulates the size of cell-cell junctionsQ33933194
The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X.Q33940427
Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner.Q33950292
Cadherin-actin interactions at adherens junctionsQ33977929
Myosin VI, a new force in clathrin mediated endocytosisQ34103649
Adherens junctions: from molecules to morphogenesisQ34122302
Possible involvement of myosin‐X in intercellular adhesion: Importance of serial pleckstrin homology regions for intracellular localizationQ34197708
Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.Q34212201
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complexQ34359173
Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3.Q34469642
Myosin VI stabilizes an actin network during Drosophila spermatid individualizationQ34662188
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cellsQ34680349
The kinetic mechanism of mouse myosin VIIAQ34685505
Unconventional Myosins, Actin Dynamics and Endocytosis: A Ménage à Trois?Q35130021
A porous defense: the leaky epithelial barrier in intestinal disease.Q35651435
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epitheliaQ35756679
The tight junction: a multifunctional complexQ35777543
The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cellsQ28513409
The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: essential role of arginine 1695Q28578515
A novel type of myosin implicated in signalling by rho family GTPasesQ28583175
Role of myosin VI in the differentiation of cochlear hair cellsQ28585164
Mutations in Cdh23, encoding a new type of cadherin, cause stereocilia disorganization in waltzer, the mouse model for Usher syndrome type 1DQ28589238
Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cellsQ28592402
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motilityQ28592732
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II familyQ28592899
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaQ28593953
Directed actin polymerization is the driving force for epithelial cell-cell adhesionQ29618861
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cellsQ30159938
Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA.Q30160385
LGN regulates mitotic spindle orientation during epithelial morphogenesisQ30434467
Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epitheliaQ30437856
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cellsQ30442081
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contactsQ30476214
Dimerized Drosophila myosin VIIa: a processive motorQ30477237
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent mannerQ30479119
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipidsQ30479852
Myosin-10 and actin filaments are essential for mitotic spindle functionQ30482632
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesisQ30484554
Pulsed contractions of an actin-myosin network drive apical constrictionQ30493161
Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundleQ30493544
The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.Q30493646
Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filamentsQ30495863
Cargo binding activates myosin VIIA motor function in cellsQ30499937
Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in DrosophilaQ30500423
Triggering a cell shape change by exploiting preexisting actomyosin contractionsQ30509509
Myosin-X functions in polarized epithelial cellsQ30513859
MYO1E mutations and childhood familial focal segmental glomerulosclerosisQ30541167
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctionsQ33292672
alpha-Catenin as a tension transducer that induces adherens junction developmentQ33572769
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complexQ33841357
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.Q33917620
Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivityQ36215124
Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosisQ36236243
The challenges of abundance: epithelial junctions and small GTPase signalling.Q36236326
Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functionsQ36236763
Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocationQ36273905
Claudins and epithelial paracellular transportQ36387912
Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope studyQ36455660
Molecular components of the adherens junction.Q36511711
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomesQ36843504
Unconventional myosins acting unconventionally.Q36929781
Actin up: regulation of podocyte structure and function by components of the actin cytoskeletonQ36931220
Morphogen control of wing growth through the Fat signaling pathway.Q37036018
Actin motors that drive formation and disassembly of epithelial apical junctionsQ37175764
The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIAQ37208900
Cargo binding induces dimerization of myosin VI.Q37366472
Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctionsQ37524262
Principles of unconventional myosin function and targetingQ37884613
Productive tension: force-sensing and homeostasis of cell-cell junctionsQ37901693
Cellular functions of class IX myosins in epithelia and immune cells.Q37936482
Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping.Q38256361
Myosin VI plays a role in cell-cell adhesion during epithelial morphogenesisQ38449026
Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesisQ39604115
Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cellsQ39735805
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
Basal-to-apical cadherin flow at cell junctionsQ40198145
Mechanism of nucleotide binding to actomyosin VI: evidence for allosteric head-head communicationQ40536919
Differential behavior of E-cadherin and occludin in their colocalization with ZO-1 during the establishment of epithelial cell polarityQ40961328
Polarized monolayers formed by epithelial cells on a permeable and translucent supportQ41233493
Rho: theme and variationsQ41238352
Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cellQ42192580
Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.Q42455765
Planar polarization of the atypical myosin Dachs orients cell divisions in DrosophilaQ42573858
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.Q42953653
The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamilyQ43709450
Association between genetic variants in myosin IXB and Crohn's disease.Q43981539
Intestinal absorptive cell tight junctions are linked to cytoskeletonQ46186998
Drosophila myosin VIIA is a high duty ratio motor with a unique kinetic mechanismQ46895770
Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesionQ47070048
A targeted gene silencing technique shows that Drosophila myosin VI is required for egg chamber and imaginal disc morphogenesis.Q47070149
Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in DrosophilaQ47070249
Mechanical control of morphogenesis by Fat/Dachsous/Four-jointed planar cell polarity pathwayQ47070449
Myosin VI is required for E-cadherin-mediated border cell migrationQ47070917
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcellQ7868
enzymeQ8047
cytoskeletal proteinsQ66563066
contractile proteinsQ69633297
macromolecular substanceQ75174158
P304page(s)158-70
P577publication date2012-01-01
2012-09-01
P1433published inBioarchitectureQ26841885
P1476titleMyosins in cell junctions
P478volume2

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cites work (P2860)
Q26785540Alterations of the apical junctional complex and actin cytoskeleton and their role in colorectal cancer progression
Q40251223Anillin regulates cell-cell junction integrity by organizing junctional accumulation of Rho-GTP and actomyosin
Q34624331Architecture of tight junctions and principles of molecular composition
Q36479371Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila.
Q92035705FABP7 is a key metabolic regulator in HER2+ breast cancer brain metastasis
Q90563988Functional roles of Grainyhead-like transcription factors in renal development and disease
Q39654406Maintenance of the Epithelial Barrier and Remodeling of Cell-Cell Junctions during Cytokinesis
Q36340660Modelling apical columnar epithelium mechanics from circumferential contractile fibres.
Q30009836Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes
Q42770464Myosin transcellular networks regulate epithelial apical geometry
Q92596369Roles of Myosin-Mediated Membrane Trafficking in TGF-β Signaling
Q60919526Target Proteins in the Dorsal Hippocampal Formation Sustain the Memory-Enhancing and Neuroprotective Effects of

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