Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells

scientific article

Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.200612042
P932PMC publication ID2064848
P698PubMed publication ID17664339
P5875ResearchGate publication ID6175498

P50authorAlpha YapQ37377160
Annette M ShewanQ58828273
P2093author name stringMadhavi P Maddugoda
Matthew S Crampton
P2860cites workThe localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulationQ22008538
Myosin VI is an actin-based motor that moves backwardsQ22010643
Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosisQ24291429
Myo6 facilitates the translocation of endocytic vesicles from cell peripheriesQ24307920
F-actin binding site masked by the intramolecular association of vinculin head and tail domainsQ24309102
alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsQ24322872
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complexQ24597349
Deconstructing the cadherin-catenin-actin complexQ24609677
Myosin VI: two distinct roles in endocytosisQ28191412
The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complexQ28289033
Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganizationQ30443460
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contactsQ30476214
Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contactsQ30476860
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complexQ33841357
Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contactsQ34117282
The ins and outs of E-cadherin traffickingQ34340762
folded gastrulation, cell shape change and the control of myosin localization.Q34445867
Myosin VI stabilizes an actin network during Drosophila spermatid individualizationQ34662188
Myosin VI, an actin motor for membrane traffic and cell migrationQ35009595
Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formationQ35362231
Vinculin is part of the cadherin-catenin junctional complex: complex formation between alpha-catenin and vinculinQ36255361
Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent proteinQ36255689
Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranesQ36398107
Regulation of cell-cell junctions by the cytoskeleton.Q36564376
Characterization of two F-actin-binding and oligomerization sites in the cell-contact protein vinculinQ38343794
Myosin VI plays a role in cell-cell adhesion during epithelial morphogenesisQ38449026
Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer miceQ39698975
Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cellsQ39735805
Rac-WAVE-mediated actin reorganization is required for organization and maintenance of cell-cell adhesion.Q40197369
Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contactsQ40293778
Characterization of an F-actin-binding domain in the cytoskeletal protein vinculinQ42770908
Three-dimensional structure of vinculin bound to actin filamentsQ44718700
The mechanism of myosin VI translocation and its load-induced anchoringQ44790017
Myosin VI altered at threonine 406 stabilizes actin filaments in vivoQ46044406
Myosin VI is required for E-cadherin-mediated border cell migrationQ47070917
Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contactsQ47438183
Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formationQ47996855
Two-headed binding of a processive myosin to F-actin.Q52863984
Actin activates a cryptic dimerization potential of the vinculin tail domainQ73316721
A role for myosin VII in dynamic cell adhesionQ73670214
Actin cable dynamics and Rho/Rock orchestrate a polarized cytoskeletal architecture in the early steps of assembling a stratified epitheliumQ78319031
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P1104number of pages12
P304page(s)529-540
P577publication date2007-07-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleMyosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells
P478volume178

Reverse relations

cites work (P2860)
Q33373673A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells
Q36433801A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.
Q53148839A bigger picture: classical cadherins and the dynamic actin cytoskeleton.
Q37159012A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton
Q42085205A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells
Q38991878Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions
Q88547133Adherens junctions influence tight junction formation via changes in membrane lipid composition
Q35642916An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization
Q35195321Apical protein transport and lumen morphogenesis in polarized epithelial cells
Q33675805Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion
Q36588911Balancing forces: architectural control of mechanotransduction
Q37333596Cadherins and cancer: how does cadherin dysfunction promote tumor progression?
Q40641225Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA.
Q30499464Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing.
Q30438289Cell adhesion receptors in mechanotransduction
Q37035184Coiled-coil-mediated dimerization is not required for myosin VI to stabilize actin during spermatid individualization in Drosophila melanogaster
Q37781561Conserved F-actin dynamics and force transmission at cell adhesions
Q37135682Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain
Q38211486Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling.
Q38449977E-cadherin junctions as active mechanical integrators in tissue dynamics
Q36423364EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt
Q47749975Epithelial Monolayers Coalesce on a Viscoelastic Substrate through Redistribution of Vinculin
Q38206254Force measurement tools to explore cadherin mechanotransduction
Q36665969Genetic characterization of the Drosophila jaguar322 mutant reveals that complete myosin VI loss of function is not lethal
Q37857739Intercellular and extracellular mechanotransduction in cardiac myocytes
Q34147630Intercellular mechanotransduction during multicellular morphodynamics
Q35747240Involvement of unconventional myosin VI in myoblast function and myotube formation.
Q27330739Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens
Q30009836Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes
Q34067428Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion
Q36191191Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens
Q34575273Myosin VI and optineurin are required for polarized EGFR delivery and directed migration
Q33957293Myosin VI contributes to synaptic transmission and development at the Drosophila neuromuscular junction.
Q34094507Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners
Q50502817Myosin VI regulates actin dynamics and melanosome biogenesis.
Q27329752Myosin VI regulates actin structure specialization through conserved cargo-binding domain sites
Q38088529Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics.
Q30416190Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells.
Q30513859Myosin-X functions in polarized epithelial cells
Q26749344Myosins as fundamental components during tumorigenesis: diverse and indispensable
Q27004163Myosins in cell junctions
Q37768293Neighborly relations: cadherins and mechanotransduction.
Q35591684New insights into vinculin function and regulation
Q83230501Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration
Q34207052Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis
Q52321911Nonmuscle myosin IIA is involved in recruitment of apical junction components through activation of α-catenin.
Q27015094Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Q39783600Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis
Q38160892Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions.
Q50436014Phospholipase Cδ3 is a novel binding partner of myosin VI and functions as anchoring of myosin VI on plasma membrane
Q37597342Potential roles of myosin VI in cell motility
Q37671129Rap1, a mercenary among the Ras-like GTPases
Q39665584Role for Traf4 in polarizing adherens junctions as a prerequisite for efficient cell shape changes
Q38747970Role of vinculin in cellular mechanotransduction
Q34036844SAX-7/L1CAM and HMR-1/cadherin function redundantly in blastomere compaction and non-muscle myosin accumulation during Caenorhabditis elegans gastrulation
Q50539828Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment.
Q37780682Spatial organization of adhesion: force-dependent regulation and function in tissue morphogenesis
Q35534690Spectrin-adducin membrane skeleton: A missing link between epithelial junctions and the actin cytoskeletion?
Q33647855Strength dependence of cadherin-mediated adhesions
Q37406209Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens
Q27678448The Cytoskeletal Protein  -Catenin Unfurls upon Binding to Vinculin
Q37267715The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.
Q97520547The Expressions and Mechanisms of Sarcomeric Proteins in Cancers
Q38155160The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane
Q36965073The juxtamembrane domain of the E-cadherin cytoplasmic tail contributes to its interaction with Myosin VI.
Q30493646The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.
Q36567245Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation
Q92156441Unconventional Myosins: How Regulation Meets Function
Q36929781Unconventional myosins acting unconventionally.
Q38946365VERO cells harbor a poly-ADP-ribose belt partnering their epithelial adhesion belt.
Q35099507Vinculin activators target integrins from within the cell to increase melanoma sensitivity to chemotherapy.
Q27009352Vinculin and metavinculin: oligomerization and interactions with F-actin
Q35839771Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
Q30577227Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions
Q33950292Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner.
Q24296424Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin
Q37775233Vinculin, an adapter protein in control of cell adhesion signalling
Q38070294Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions
Q36425571Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation.
Q36620828α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength
Q35801858α-Catenin uses a novel mechanism to activate vinculin

Search more.