Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes

scientific article published on 12 June 2013

Myosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1152/AJPRENAL.00223.2013
P3181OpenCitations bibliographic resource ID3897191
P932PMC publication ID3891261
P698PubMed publication ID23761676
P5875ResearchGate publication ID237200286

P50authorMira KrendelQ56863465
P2093author name stringA S Fanning
H Kurihara
J Bi
S E Chase
C D Pellenz
P2860cites workHuman brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cellsQ22008561
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosisQ24294756
Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membraneQ24297240
Myo1e binds anionic phospholipids with high affinityQ24300535
Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndromeQ24314612
Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domainQ24323991
Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrinQ24670040
Myosins in cell junctionsQ27004163
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndromeQ28116208
Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosisQ28145757
CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibilityQ28206197
A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctionsQ28211256
The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeletonQ28287040
Vezatin, a protein associated to adherens junctions, is required for mouse blastocyst morphogenesisQ28505350
Modulation of cell adhesion and motility in the immune system by Myo1fQ28508243
Disruption of Myosin 1e promotes podocyte injuryQ28509726
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctionsQ28511375
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in miceQ28511656
Slit diaphragms contain tight junction proteinsQ28573180
Lifeact: a versatile marker to visualize F-actinQ29547604
Targeting of the myosin-I myr 3 to intercellular adherens type junctions induced by dominant active Cdc42 in HeLa cells.Q30176076
A novel mammalian myosin I from rat with an SH3 domain localizes to Con A-inducible, F-actin-rich structures at cell-cell contactsQ30193460
The GPQ-rich segment of Dictyostelium myosin IB contains an actin binding siteQ30194483
Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contactsQ30476214
Myosin-X functions in polarized epithelial cellsQ30513859
Molecular basis of dynamic relocalization of Dictyostelium myosin IBQ30513892
Role of dynamin, synaptojanin, and endophilin in podocyte foot processesQ30530966
MYO1E mutations and childhood familial focal segmental glomerulosclerosisQ30541167
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctionsQ33292672
Leveraging the membrane - cytoskeleton interface with myosin-1.Q33965456
Cadherin-actin interactions at adherens junctionsQ33977929
Alteration of epithelial structure and function associated with PtdIns(4,5)P2 degradation by a bacterial phosphataseQ34612727
Cell biology of the glomerular podocyteQ35035937
Marker expression, behaviors, and responses vary in different lines of conditionally immortalized cultured podocytesQ35216791
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epitheliaQ35756679
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctionsQ35785344
A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulationQ36066631
Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cellsQ36119767
Podocyte-specific knockout of myosin 1e disrupts glomerular filtrationQ36312646
Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation.Q36425571
Diversity among tight junctions in rat kidney: glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1Q37135383
Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouseQ37530481
Signaling from the podocyte intercellular junction to the actin cytoskeletonQ38041666
The actin binding site in the tail domain of Dictyostelium myosin IC (myoC) resides within the glycine- and proline-rich sequence (tail homology region 2).Q38309336
PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42.Q40178894
Mechanical force-activated phospholipase D is mediated by Galpha12/13-Rho and calmodulin-dependent kinase in renal epithelial cellsQ40417640
Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formationQ40432728
Stable expression of nephrin and localization to cell-cell contacts in novel murine podocyte cell linesQ40544739
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.Q41084039
Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and functionQ41196444
The MDCK epithelial cell line expresses a cell surface antigen of the kidney distal tubuleQ41440988
SIRP-alpha-CD47 system functions as an intercellular signal in the renal glomerulusQ43017126
A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families.Q51063406
Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndromeQ57980301
Ontogenetic development of the filtration barrierQ80482293
P433issue4
P304page(s)F532-44
P577publication date2013-06-12
P1433published inAmerican Journal of Physiology - Renal PhysiologyQ2610177
P1476titleMyosin 1e is a component of the glomerular slit diaphragm complex that regulates actin reorganization during cell-cell contact formation in podocytes
P478volume305

Reverse relations

cites work (P2860)
Q43104723Class I myosin Myo1e regulates TLR4-triggered macrophage spreading, chemokine release, and antigen presentation via MHC class II.
Q37202510Development of a Functional Glomerulus at the Organ Level on a Chip to Mimic Hypertensive Nephropathy
Q35923475Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast
Q64119419Effects of Xiaoyaosan on the Hippocampal Gene Expression Profile in Rats Subjected to Chronic Immobilization Stress
Q34674987Genetic causes of proteinuria and nephrotic syndrome: impact on podocyte pathobiology
Q38819528Glomerular pathology and the progression of chronic kidney disease
Q90201440Human myosin 1e tail but not motor domain replaces fission yeast Myo1 domains to support myosin-I function during endocytosis
Q42038185Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy
Q92357066Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background
Q33604005Myosin 1e is a component of the invadosome core that contributes to regulation of invadosome dynamics
Q37564758Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation
Q37120373Myosin-I molecular motors at a glance
Q34207052Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis
Q57471573Phosphoinositides in the kidney
Q27004073Podocyte endocytosis in the regulation of the glomerular filtration barrier
Q34361995Visualization of cytoskeletal dynamics in podocytes using adenoviral vectors

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