Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia

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Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E09-01-0023
P932PMC publication ID2777933
P698PubMed publication ID19553471

P50authorAlpha YapQ37377160
Nicole Den ElzenQ55298817
P2093author name stringGang Ren
Madhavi P Maddugoda
Carmen V Buttery
P2860cites workAMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membraneQ24297032
Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteinsQ24313402
APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignmentQ24536199
Actin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cellsQ28363074
Direct cadherin-activated cell signaling: a view from the plasma membraneQ28756060
Experimental and theoretical study of mitotic spindle orientationQ29396188
Morphogenetic roles of classic cadherinsQ29614941
Asymmetric cell divisions promote stratification and differentiation of mammalian skinQ29620393
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cellsQ30442081
Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contactsQ30476860
Mammalian spindle orientation and position respond to changes in cell shape in a dynein-dependent fashionQ30477500
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent mannerQ30479119
Cadherins in embryonic and neural morphogenesisQ33938474
Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contactsQ34117282
Asymmetric cell division: fly neuroblast meets worm zygoteQ34132774
Asymmetric cell division.Q34326914
Adhesion signaling: how beta-catenin interacts with its partnersQ34395476
Dynein at the cortexQ34495155
Asymmetric cell division: microtubule dynamics and spindle asymmetry.Q34634844
Control of cell polarity and mitotic spindle positioning in animal cellsQ35041105
Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebratesQ35868625
Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cellsQ36534977
Cell shape and cell divisionQ36625784
Cell regulation by the Apc protein Apc as master regulator of epithelia.Q37116480
The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin.Q37204309
Planar spindle orientation and asymmetric cytokinesis in the mouse small intestineQ38317735
Morphogenesis of the polarized epithelial cell phenotypeQ38684855
A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells.Q40811578
Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of beta -catenin signalingQ40889576
The role of DE-cadherin during cellularization, germ layer formation and early neurogenesis in the Drosophila embryoQ42462757
Adherens junctions inhibit asymmetric division in the Drosophila epitheliumQ42499987
Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineageQ42516585
Dynein binds to beta-catenin and may tether microtubules at adherens junctions.Q43754950
E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contactsQ43823908
Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesionQ47070048
The orientation of cell divisions determines the shape of Drosophila organs.Q47070632
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in DrosophilaQ47072837
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.Q52100403
Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells.Q52187841
Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.Q52591547
Spindle misorientation in tumors from APC(min/+) mice.Q53314237
The extracellular matrix guides the orientation of the cell division axis.Q53656268
Cytokinesis in animal cellsQ68760577
P433issue16
P304page(s)3740-3750
P577publication date2009-06-24
P1433published inMolecular Biology of the CellQ2338259
P1476titleCadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia
P478volume20

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cites work (P2860)
Q89108028Aberrant endocytosis leads to the loss of normal mitotic spindle orientation during epithelial glandular morphogenesis
Q60301609Actomyosin-Driven Tension at Compartmental Boundaries Orients Cell Division Independently of Cell Geometry In Vivo
Q38016773Adherens junctions and stem cells.
Q34122302Adherens junctions: from molecules to morphogenesis
Q35818227An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype
Q58067537Analysis of a vinculin homolog in a sponge (phylum Porifera) reveals that vertebrate-like cell adhesions emerged early in animal evolution
Q33769261Cadherins and Pak1 control contact inhibition of proliferation by Pak1-betaPIX-GIT complex-dependent regulation of cell-matrix signaling.
Q34168468Cell adhesion in regulation of asymmetric stem cell division
Q38677606Cell adhesion molecule control of planar spindle orientation.
Q26858973Cell division and the maintenance of epithelial order
Q37562683Cell division orientation is coupled to cell-cell adhesion by the E-cadherin/LGN complex
Q35679252Cell shape impacts on the positioning of the mitotic spindle with respect to the substratum.
Q42514755Cell-cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions.
Q38248934Centrosome positioning in polarized cells: common themes and variations.
Q36497518Centrosome positioning in vertebrate development
Q26785528Connections between cadherin-catenin proteins, spindle misorientation, and cancer
Q35041609Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation
Q41148057E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape
Q33687283E-cadherin is required for centrosome and spindle orientation in Drosophila male germline stem cells
Q27313451Effect of Cell Shape and Dimensionality on Spindle Orientation and Mitotic Timing
Q91942694Eph signaling controls mitotic spindle orientation and cell proliferation in neuroepithelial cells
Q30495669Epicardial spindle orientation controls cell entry into the myocardium
Q37968480Epithelial cell polarity, stem cells and cancer
Q26825041Epithelial polarity--generating and integrating signals from the ECM with integrins
Q64243670Evolution as a guide for experimental cell biology
Q50627126FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis.
Q27009493Force and the spindle: mechanical cues in mitotic spindle orientation
Q37725724Hereditary diffuse gastric cancer: translation of CDH1 germline mutations into clinical practice.
Q30427386Integrins and cadherins join forces to form adhesive networks
Q27313566Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1.
Q36030193JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis.
Q30434467LGN regulates mitotic spindle orientation during epithelial morphogenesis
Q38015243Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy
Q47132771Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells.
Q93019680MARK2/Par1b kinase present at centrosomes and retraction fibres corrects spindle off-centring induced by actin disassembly
Q39571912Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation
Q52623886Mechanisms of Trabecular Formation and Specification During Cardiogenesis.
Q34389292Mechanisms of regulating cell topology in proliferating epithelia: impact of division plane, mechanical forces, and cell memory
Q26781371Micro- and nanodevices integrated with biomolecular probes
Q33605145Miniaturized pre-clinical cancer models as research and diagnostic tools
Q27330120Mitosis in neurons: Roughex and APC/C maintain cell cycle exit to prevent cytokinetic and axonal defects in Drosophila photoreceptor neurons
Q36417737Mitotic cells contract actomyosin cortex and generate pressure to round against or escape epithelial confinement
Q36191191Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens
Q30513859Myosin-X functions in polarized epithelial cells
Q27004163Myosins in cell junctions
Q42428878PAR-6, but not E-cadherin and β-integrin, is necessary for epithelial polarization in C. elegans
Q37267940Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes.
Q36823704Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation.
Q38160892Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions.
Q38107433Random chromosome segregation in mouse intestinal epithelial stem cells.
Q62485079Role of adherens junctions and apical-basal polarity of neural stem/progenitor cells in the pathogenesis of neurodevelopmental disorders: a novel perspective on congenital Zika syndrome
Q27315980Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland
Q36784413Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification
Q35903531Spindle position in symmetric cell divisions during epiboly is controlled by opposing and dynamic apicobasal forces
Q52641939Structural centrosome aberrations promote non-cell-autonomous invasiveness.
Q39409518Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance.
Q42464662Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages
Q39242330Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division.
Q34692456Syntaxin 16 regulates lumen formation during epithelial morphogenesis.
Q28255263The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis
Q34345692The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells
Q39242277The Midbody and its Remnant in Cell Polarization and Asymmetric Cell Division
Q38869306The ins(ide) and outs(ide) of asymmetric stem cell division
Q58740977The last-born daughter cell contributes to division orientation of Drosophila larval neuroblasts
Q37405061The p38-interacting protein (p38IP) regulates G2/M progression by promoting α-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5.
Q39000953The special case of hepatocytes: unique tissue architecture calls for a distinct mode of cell division
Q35057143Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity
Q47365590Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells
Q37583348Type VII collagen regulates expression of OATP1B3, promotes front-to-rear polarity and increases structural organisation in 3D spheroid cultures of RDEB tumour keratinocytes.
Q38734544ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture.
Q43121393Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions
Q38271411p600/UBR4 in the central nervous system

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