| scholarly article | Q13442814 |
| P356 | DOI | 10.1083/JCB.201002097 |
| P8608 | Fatcat ID | release_3rtswxa6ibbqbn6wn6hy3gaegu |
| P932 | PMC publication ID | 2872902 |
| P698 | PubMed publication ID | 20479467 |
| P5875 | ResearchGate publication ID | 44608457 |
| P2093 | author name string | Ian G Macara | |
| Yi Hao | |||
| Yi Qin | |||
| Walter H Meisen | |||
| P2860 | cites work | The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 | Q22254751 |
| Direct interaction of two polarity complexes implicated in epithelial tight junction assembly | Q24293221 | ||
| Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6 | Q24296040 | ||
| Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins | Q24313402 | ||
| Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells | Q24678887 | ||
| Tuba, a Novel Protein Containing Bin/Amphiphysin/Rvs and Dbl Homology Domains, Links Dynamin to Regulation of the Actin Cytoskeleton | Q28204673 | ||
| A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells | Q28238594 | ||
| Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta | Q28583531 | ||
| Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration | Q28590412 | ||
| Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. | Q30436000 | ||
| The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis | Q30437640 | ||
| Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis | Q30484554 | ||
| Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans | Q30503202 | ||
| Bud-site selection and cell polarity in budding yeast. | Q34588867 | ||
| Similar requirements for CDC-42 and the PAR-3/PAR-6/PKC-3 complex in diverse cell types | Q35899515 | ||
| Insulin and PIP3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites | Q39423459 | ||
| Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. | Q39745580 | ||
| PTEN-mediated apical segregation of phosphoinositides controls epithelial morphogenesis through Cdc42. | Q40178894 | ||
| Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly | Q40782515 | ||
| PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex. | Q40782848 | ||
| A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity | Q40862977 | ||
| Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC. | Q41700895 | ||
| Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts. | Q43144220 | ||
| Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos | Q47069527 | ||
| Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. | Q47397341 | ||
| CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos. | Q52010283 | ||
| Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. | Q52100403 | ||
| Cdc42 is crucial for the establishment of epithelial polarity during early mammalian development | Q57510560 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cyst | Q193211 |
| P1104 | number of pages | 9 | |
| P304 | page(s) | 661-669 | |
| P577 | publication date | 2010-05-01 | |
| P1433 | published in | Journal of Cell Biology | Q1524550 |
| P1476 | title | Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation | |
| P478 | volume | 189 |
| Q58588103 | A Tuba/Cdc42/Par6A complex is required to ensure singularity in apical domain formation during enterocyte polarization |
| Q38722222 | A Two-Tiered Mechanism Enables Localized Cdc42 Signaling during Enterocyte Polarization |
| Q42116509 | A molecular network for de novo generation of the apical surface and lumen |
| Q89108028 | Aberrant endocytosis leads to the loss of normal mitotic spindle orientation during epithelial glandular morphogenesis |
| Q36981654 | An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium |
| Q36595837 | Apicobasal polarity of brain endothelial cells |
| Q38657529 | Arg kinase regulates epithelial cell polarity by targeting β1-integrin and small GTPase pathways |
| Q36547115 | Asymmetric cell divisions in the epidermis |
| Q90470133 | Autoactivation of small GTPases by the GEF-effector positive feedback modules |
| Q35780286 | Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice |
| Q37119933 | Cdc42 deficiency causes ciliary abnormalities and cystic kidneys. |
| Q38677606 | Cell adhesion molecule control of planar spindle orientation. |
| Q38033611 | Cell polarity as a regulator of cancer cell behavior plasticity |
| Q35679252 | Cell shape impacts on the positioning of the mitotic spindle with respect to the substratum. |
| Q34533478 | Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structure |
| Q42240156 | Control of Rho GTPase function by BAR-domains |
| Q39038189 | Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation |
| Q35041609 | Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation |
| Q36884672 | Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo |
| Q64100845 | Dynamin Binding Protein Is Required for Kidney Development |
| Q30525035 | Dynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation |
| Q38827611 | Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells. |
| Q37968480 | Epithelial cell polarity, stem cells and cancer |
| Q26825041 | Epithelial polarity--generating and integrating signals from the ECM with integrins |
| Q33980507 | Establishment of epithelial polarity--GEF who's minding the GAP? |
| Q43159984 | Host endoplasmic reticulum COPII proteins control cell-to-cell spread of the bacterial pathogen Listeria monocytogenes |
| Q38284377 | I'm coming to GEF you: Regulation of RhoGEFs during cell migration |
| Q97522672 | IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules |
| Q88688776 | Insane in the apical membrane: Trafficking events mediating apicobasal epithelial polarity during tube morphogenesis |
| Q36030193 | JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. |
| Q92020476 | Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment |
| Q34294183 | Listeria monocytogenes antagonizes the human GTPase Cdc42 to promote bacterial spread |
| Q64929103 | Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1-Tea4-Pom1 axis. |
| Q64971000 | Mechanistic Insights into Colorectal Cancer Phenomics from Fundamental and Organotypic Model Studies. |
| Q90854375 | Mesenchymal-epithelial transition in development and reprogramming |
| Q37863911 | Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting |
| Q27006985 | Molecular mechanism of protrusion formation during cell-to-cell spread of Listeria |
| Q37837188 | Molecular regulation of lumen morphogenesis. |
| Q30581661 | Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease |
| Q30513859 | Myosin-X functions in polarized epithelial cells |
| Q36234461 | Nonredundant roles of cytoplasmic β- and γ-actin isoforms in regulation of epithelial apical junctions |
| Q27015094 | Normal morphogenesis of epithelial tissues and progression of epithelial tumors |
| Q44027425 | Opening ahead: early steps in lumen formation revealed |
| Q38197884 | Organization and execution of the epithelial polarity programme |
| Q37382529 | PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system |
| Q37267940 | Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes. |
| Q30430174 | Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins |
| Q30499299 | Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis |
| Q35119240 | Phosphoinositides in cell architecture. |
| Q26830318 | Polarity in mammalian epithelial morphogenesis |
| Q37267919 | Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures |
| Q37453807 | Rab14 specifies the apical membrane through Arf6-mediated regulation of lipid domains and Cdc42. |
| Q37903873 | Regulation of small GTPases at epithelial cell-cell junctions |
| Q42326441 | Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. |
| Q38196268 | Rewiring cell polarity signaling in cancer |
| Q26992281 | Rho GAPs and GEFs: controling switches in endothelial cell adhesion |
| Q26865752 | Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking |
| Q42505499 | Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis |
| Q93086454 | SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility |
| Q34216354 | Spindle orientation: what if it goes wrong? |
| Q39409518 | Suppression of Rac1 activity at the apical membrane of MDCK cells is essential for cyst structure maintenance. |
| Q34345692 | The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells |
| Q35693836 | The Rho GTPase Cdc42 is required for primary mammary epithelial cell morphogenesis in vitro |
| Q34313436 | The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. |
| Q36528106 | The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42 |
| Q30009264 | The interdependence of the Rho GTPases and apicobasal cell polarity |
| Q35063130 | The small GTPase Cdc42 is necessary for primary ciliogenesis in renal tubular epithelial cells |
| Q30613021 | The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion |
| Q35534085 | Tuba and N-WASP function cooperatively to position the central lumen during epithelial cyst morphogenesis |
| Q27343136 | Two distinct integrin-mediated mechanisms contribute to apical lumen formation in epithelial cells |
| Q37580163 | Vitamin D3 suppresses morphological evolution of the cribriform cancerous phenotype |
| Q38734544 | ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. |
| Q36462440 | p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK-myosin-II pathway |
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